hydralazine has been researched along with Collagen Diseases in 25 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Collagen Diseases: Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that collagen was equivalent to connective tissue, but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term collagen diseases now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The collagen-like syndrome was induced in rats by hydralazine application during 5 months." | 7.67 | Glucose tolerance in rats with hydralazine-induced collagen-like syndrome. ( Jendryczko, A; Kucharz, E, 1984) |
| "LE-positive collagen-like syndrome was produced in rats with chronic hydralazine treatment." | 7.67 | Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication. ( Jendryczko, A; Kucharz, E, 1984) |
| "The excretion of the two hydroxylysine glycosides hydroxylysine-galactose-glucose and hydroxylysine-galactose was studied in the urine of normal healthy and experimental rats chronically treated with collagen-like syndrome inductors, hydralazine or binazine." | 7.67 | Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome. ( Drozdz, M; Jendryczko, A; Magner, K, 1985) |
| "The collagen-like syndrome was induced in rats by hydralazine application during 5 months." | 3.67 | Glucose tolerance in rats with hydralazine-induced collagen-like syndrome. ( Jendryczko, A; Kucharz, E, 1984) |
| "LE-positive collagen-like syndrome was produced in rats with chronic hydralazine treatment." | 3.67 | Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication. ( Jendryczko, A; Kucharz, E, 1984) |
| "The excretion of the two hydroxylysine glycosides hydroxylysine-galactose-glucose and hydroxylysine-galactose was studied in the urine of normal healthy and experimental rats chronically treated with collagen-like syndrome inductors, hydralazine or binazine." | 3.67 | Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome. ( Drozdz, M; Jendryczko, A; Magner, K, 1985) |
| "An increase of soluble fractions of collagen and a decrease of insoluble ones was found in the skin of guinea pigs with collagen disease-like syndrome, produced by prolonged treatment with hydralazine." | 3.66 | Increased solubility of collagen. A biochemical defect in the experimental hydralizine-induced collagen disease-like syndrome. ( Drózdz, M; Kucharz, E, 1978) |
| "A collagen-like syndrome was produced by a long-term administration of 1-hydrazinophthalazine (hydralazine) to guinea pigs." | 3.65 | Serum glycoproteins level and urinary glycosaminoglycans excretion in drug induced collagen-like syndrome in guinea pigs. ( Drózdz, M; Kucharz, E, 1976) |
| " It has been stated that the long-term administration of hydralazine caused the lowering of the retinol level in the serum and liver progressing according to the time of the drug use." | 1.28 | [Retinol level, superoxide dismutase activity and the degree of lipid peroxidation in rats with drug-induced collagenosis]. ( Drózdz, M; Magner-Wróbel, K, 1990) |
| " Changes in hydrazinophthalazine-treated rats after dosing them with isoprenaline had a similar tendency but they were significantly lower than those found in healthy animals receiving isoprenaline only." | 1.27 | Effect of isoprenaline on tissue elastin content and serum elastolytic activity in normal and hydrazinophthalazine-treated rats. ( Drózdz, M; Kucharz, E; Olczyk, K; Wieczorek, M, 1987) |
| " It was found that long-term administration of hydralazine caused a decrease of erythrocyte count, a decrease of haemoglobin concentration and a decrease of haemoglobin content in individual red blood cell as well as a decrease of a single erythrocyte volume." | 1.26 | Haematological changes in experimental hydralazine-induced collagen-like syndrome in guinea pigs. ( Dróźdź, M; Kucharz, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (92.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PERRY, HM | 1 |
| SCHROEDER, HA | 1 |
| MULLER, JC | 1 |
| RAST, CL | 1 |
| PRYOR, WW | 1 |
| ORGAIN, ES | 1 |
| REYNOLDS, H | 1 |
| CALDWELL, JR | 1 |
| MONIER, JC | 1 |
| OSHIMA, Y | 1 |
| HAZAMA, T | 1 |
| Alarcón-Segovia, D | 1 |
| Wakim, KG | 1 |
| Worthington, JW | 1 |
| Ward, LE | 1 |
| Jendryczko, A | 6 |
| Kucharz, E | 9 |
| Drózdz, M | 14 |
| Piwowarczyk, B | 1 |
| Olczyk, K | 3 |
| Feluś, E | 1 |
| Wieczorek, M | 3 |
| Głowacki, A | 1 |
| Kucharz, EJ | 1 |
| Podymov, VK | 1 |
| Gladkikh, SP | 1 |
| Piruzian, LA | 1 |
| Magner-Wróbel, K | 1 |
| Magner, K | 2 |
| Kula, B | 1 |
| Wardas, M | 1 |
| Weglarz, L | 1 |
| Skop, B | 1 |
25 other studies available for hydralazine and Collagen Diseases
| Article | Year |
|---|---|
Syndrome simulating collagen disease caused by hydralazine (Apresoline).
Topics: Collagen; Collagen Diseases; Hydralazine; Hypertension; Sympatholytics; Syndrome | 1954 |
Late systemic complications of hydralazine (apresoline) therapy.
Topics: Collagen; Collagen Diseases; Hydralazine; Sympatholytics | 1955 |
Hydralazine syndrome; hypersensitivity or toxicity? its significance in understanding of collagen disease.
Topics: Arthritis; Arthritis, Rheumatoid; Collagen Diseases; Humans; Hydralazine; Hydrazines | 1957 |
[Collagenosis after hydrazine administration in the rat].
Topics: Animals; Collagen Diseases; Hydralazine; Hydrazines; Rats | 1960 |
[IMMUNOLOGICAL ASPECTS OF COLLAGEN DISEASES].
Topics: Agammaglobulinemia; Allergy and Immunology; Anticonvulsants; Antigens; Autoantibodies; Collagen Dise | 1964 |
[COLLAGEN DISEASES].
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Rheumatoid; Behcet Syndrome; Child; Collagen Disease | 1964 |
Clinical and experimental studies on the hydralazine syndrome and its relationship to systemic lupus erythematosus.
Topics: Adult; Aged; Animals; Collagen Diseases; Dogs; Female; Humans; Hydralazine; Lupus Erythematosus, Sys | 1967 |
Glucose tolerance in rats with hydralazine-induced collagen-like syndrome.
Topics: Animals; Blood Glucose; Collagen Diseases; Fasting; Glucose Tolerance Test; Hydralazine; Hyperglycem | 1984 |
Blood histamine level in rats with hydralazine-induced collagen-like syndrome. Short communication.
Topics: Animals; Collagen Diseases; Histamine; Hydralazine; Rats; Rats, Inbred Strains; Syndrome | 1984 |
Studies on collagenolytic cathepsin activity in rats with experimental collagen-like syndrome.
Topics: Animals; Cathepsins; Collagen; Collagen Diseases; Hydralazine; Kidney; Male; Rats; Rats, Inbred Stra | 1983 |
Antiglobulin antibodies in blood serum of rabbits hyperimmunized with bovine albumin and treated chronically with hydrazinophtalazines.
Topics: Animals; Antibodies, Anti-Idiotypic; Collagen Diseases; Female; Hydralazine; Immunization, Secondary | 1981 |
Histopathological changes in rabbits with long-term treatment with hydrazinophtalazines with or without hyperimmunization.
Topics: Animals; Collagen Diseases; Hydralazine; Immunization, Secondary; Kidney; Myocardium; Rabbits; Serum | 1981 |
Glycosaminoglycan-collagen interactions in vitro in the hydralazine-induced collagen disease-like syndrome.
Topics: Animals; Collagen; Collagen Diseases; Disease Models, Animal; Glycosaminoglycans; Hydralazine; Male; | 1993 |
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands].
Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; I | 1979 |
Haematological changes in experimental hydralazine-induced collagen-like syndrome in guinea pigs.
Topics: Animals; Cell Count; Collagen Diseases; Erythrocytes; Guinea Pigs; Hematocrit; Hemoglobins; Hydralaz | 1978 |
Histopathological changes in experimental drug-induced collagen disease-like syndrome.
Topics: Animals; Blood Vessels; Collagen Diseases; Connective Tissue; Guinea Pigs; Hydralazine; Inflammation | 1977 |
Increased solubility of collagen. A biochemical defect in the experimental hydralizine-induced collagen disease-like syndrome.
Topics: Animals; Chromatography; Collagen; Collagen Diseases; Hydralazine; Solubility; Swine; Syndrome | 1978 |
Serum glycoproteins level and urinary glycosaminoglycans excretion in drug induced collagen-like syndrome in guinea pigs.
Topics: Animals; Collagen Diseases; Disease Models, Animal; Glycoproteins; Glycosaminoglycans; Guinea Pigs; | 1976 |
[Retinol level, superoxide dismutase activity and the degree of lipid peroxidation in rats with drug-induced collagenosis].
Topics: Animals; Collagen Diseases; Disease Models, Animal; Female; Hydralazine; Lipid Peroxidation; Liver; | 1990 |
Antilupus activity of copper (II).
Topics: Animals; Collagen Diseases; Copper; Free Radicals; Hydralazine; Lupus Erythematosus, Systemic; Male; | 1985 |
Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome.
Topics: Animals; Collagen; Collagen Diseases; Glycosides; Hydralazine; Hydroxylysine; Male; Neutrophils; Rat | 1985 |
Hyaluronic acid content and hyaluronidase activity in liver and spleen of rats with hydralazine-induced collagen-like syndrome.
Topics: Animals; Collagen Diseases; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydralazine; Liver; Male; Rat | 1988 |
Serum lipid peroxide level and blood superoxide dismutase activity in rats with hydralazine-induced collagenosis-like syndrome.
Topics: Animals; Collagen Diseases; Hydralazine; Lipid Peroxides; Male; Rats; Rats, Inbred Strains; Superoxi | 1988 |
Cartilage degradation by neutral metalloproteases in experimental collagen-like syndrome.
Topics: Animals; Cartilage; Collagen Diseases; Hydralazine; Male; Metalloendopeptidases; Proteoglycans; Rats | 1988 |
Effect of isoprenaline on tissue elastin content and serum elastolytic activity in normal and hydrazinophthalazine-treated rats.
Topics: Animals; Cardiomyopathies; Collagen Diseases; Elastin; Hydralazine; Isoproterenol; Male; Pancreatic | 1987 |