Page last updated: 2024-10-28

hydralazine and Chronic Disease

hydralazine has been researched along with Chronic Disease in 105 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
" placebo (H-HeFT) and 2) if metformin reduces the incidence of death, worsening heart failure, acute myocardial infarction, and stroke vs."9.41The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr ( Abdulla, J; Barasa, A; Bibby, BM; Bruun, NE; Brønnum-Schou, J; Bøtker, HE; Bøttcher, M; Dodt, K; Eiskjær, H; Gislason, G; Gustafsson, F; Hansen, VB; Hassager, C; Hollingdal, M; Høfsten, DE; Jonczy, B; Knudsen, AS; Kristensen, SL; Køber, L; Larsen, AH; Lomholdt, J; Madsen, JS; Mahboubi, K; Mellemkjær, S; Mikkelsen, KV; Møller, J; Nielsen, G; Nielsen, OW; Nørrelund, H; Poenaru, MP; Poulsen, MK; Raymond, I; Refsgaard, J; Schou, M; Serup-Hansen, K; Sillesen, K; Steffensen, FH; Torp-Petersen, C; Vraa, S; Wiggers, H, 2021)
"The similar two-year mortality in the hydralazine-isosorbide dinitrate arms in our previous Vasodilator-Heart Failure Trial (26 percent) and in the present trial (25 percent), as compared with that in the placebo arm in the previous trial, (34 percent) and the further survival benefit with enalapril in the present trial (18 percent) strengthen the conclusion that vasodilator therapy should be included in the standard treatment for heart failure."9.07A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. ( Cobb, F; Cohn, JN; Dunkman, WB; Francis, G; Johnson, G; Loeb, H; Smith, R; Tristani, F; Wong, M; Ziesche, S, 1991)
" Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril."9.07Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991)
"Hydralazine (H) and nitrates (Ns), when combined, reduced morbidity and mortality in some trials of chronic heart failure (CHF)."8.91Hydralazine and nitrates alone or combined for the management of chronic heart failure: A systematic review. ( Clark, AL; Cleland, JG; Farag, M; Mabote, T; Nabhan, AF; Shoaib, A; Zhang, J, 2015)
"Nine male patients with stable chronic heart failure of different etiology and optimally treated with digoxine and diuretics were given hydralazine, 50 mg b."7.67Improved cardiac performance during exercise following hydralazine treatment in chronic heart failure. ( Conradson, TB; Rydén, L, 1984)
"In rats with large myocardial infarctions, we compared the effects of captopril, a presumed arterial and venous vasodilator, with hydralazine, which is thought primarily to be an arterial vasodilator."7.67Importance of venodilatation in prevention of left ventricular dilatation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine. ( Aguirre, M; Gay, RG; Goldman, S; Raya, TE, 1989)
"The comparative haemodynamic effects of oral prazosin hydrochloride and hydralazine were evaluated in 11 patients with chronic congestive heart failure."7.66Comparison of haemodynamic effects of oral hydralazine and prazosin hydrochloride in patients with chronic congestive heart failure. ( Arnold, S; Brundage, B; Chatterjee, K; Parmley, W; Ports, TA, 1979)
"Simultaneous hemodynamic and radionuclide angiographic assessment was made at rest and during exercise in nine patients with severe chronic congestive heart failure to determine the value of radionuclide left ventricular ejection fraction measurement in predicting the hemodynamic response to short-term treatment with oral hydralazine."7.66Hydralazine therapy in severe chronic heart failure: inability of radionuclide left ventricular ejection fraction measurement to predict the hemodynamic response. ( Franklin, BA; Goldberg, MJ; Kerin, NZ; Rubenfire, M; Ruskin, R; Willens, HJ, 1983)
"We studied the hemodynamic response to orally administered hydralazine (30 mg) and examined the changes in neurohumoral factors in 16 aged patients with chronic congestive heart failure."7.66Effect of orally administered hydralazine on neurohumoral factors and hemodynamic response in aged patients with chronic congestive heart failure. ( Kuwajima, I; Matsushita, S; Murakami, M; Sakai, M; Ueda, K, 1983)
"Several reports have suggested that because isosorbide dinitrate and hydralazine have different and additive haemodynamic effects at rest in patients with chronic heart failure, these agents should be administered in combination."7.66Vasodilator treatment with isosorbide dinitrate and hydralazine in chronic heart failure. ( Haughom, F; Kramer, B; Massie, BM; Shen, E, 1981)
"We studied the effect of vasodilator therapy on renal digoxin clearance in patients with chronic congestive heart failure."7.66Acute vasodilator therapy increases renal clearance of digoxin in patients with congestive heart failure. ( Benowitz, NL; Carlson, CJ; Cogan, JJ; Humphreys, MH; Rapaport, E, 1981)
"The haemodynamic effects of oral prazosin and hydralazine were evaluated in patients with refractory heart failure and compared with those of intravenous nitroprusside in the same patients."7.66Comparison of haemodynamic effects of oral prazosin, oral hydralazine, and intravenous nitroprusside in same patients with chronic heart failure. ( Conti, CR; Iacona, M; Mehta, J; Pepine, CJ, 1979)
"To examine the importance of left ventricular chamber size in determing the response to vasodilator therapy, we performed echocardiography in 40 patients with chronic refractory heart failure before they were treated with oral hydralazine."7.66Importance of left ventricular chamber size in determining the response to hydralazine in severe chronic heart failure. ( Gorlin, R; Herman, MV; Medina, N; Meller, J; Packer, M, 1980)
"The hemodynamic effects of oral hydralazine were investigated in ten patients (nine in NYHA Class IV and one in Class III) with chronic refractory heart failure."7.65Oral hydralazine therapy for chronic refractory heart failure. ( Chatterjee, K; Greenberg, B; Klausner, S; Massie, B; Norman, A; Parmley, WW; Werner, J, 1976)
"Congestive heart failure is accompanied by a number of compensatory mechanisms that may overshoot the mark."6.37Role of isosorbide dinitrate in management of chronic congestive heart failure. ( Parmley, WW, 1985)
" placebo (H-HeFT) and 2) if metformin reduces the incidence of death, worsening heart failure, acute myocardial infarction, and stroke vs."5.41The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr ( Abdulla, J; Barasa, A; Bibby, BM; Bruun, NE; Brønnum-Schou, J; Bøtker, HE; Bøttcher, M; Dodt, K; Eiskjær, H; Gislason, G; Gustafsson, F; Hansen, VB; Hassager, C; Hollingdal, M; Høfsten, DE; Jonczy, B; Knudsen, AS; Kristensen, SL; Køber, L; Larsen, AH; Lomholdt, J; Madsen, JS; Mahboubi, K; Mellemkjær, S; Mikkelsen, KV; Møller, J; Nielsen, G; Nielsen, OW; Nørrelund, H; Poenaru, MP; Poulsen, MK; Raymond, I; Refsgaard, J; Schou, M; Serup-Hansen, K; Sillesen, K; Steffensen, FH; Torp-Petersen, C; Vraa, S; Wiggers, H, 2021)
"Prudence is indicated in patients with congestive heart failure due to coronary artery disease."5.27A review of the long-term effects of prazosin and hydralazine in chronic congestive heart failure. ( Rutishauser, W, 1983)
"The similar two-year mortality in the hydralazine-isosorbide dinitrate arms in our previous Vasodilator-Heart Failure Trial (26 percent) and in the present trial (25 percent), as compared with that in the placebo arm in the previous trial, (34 percent) and the further survival benefit with enalapril in the present trial (18 percent) strengthen the conclusion that vasodilator therapy should be included in the standard treatment for heart failure."5.07A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. ( Cobb, F; Cohn, JN; Dunkman, WB; Francis, G; Johnson, G; Loeb, H; Smith, R; Tristani, F; Wong, M; Ziesche, S, 1991)
"We compared the effects of Hydralazine and Isosorbide dinitrate (ISDN) with those of an angiotensin-converting-enzyme inhibitor, captopril on mortality in patients with chronic congestive heart failure (NYHA class III and IV)."5.07Effect of vasodilator therapy on mortality in chronic congestive heart failure. ( Bhandari, B; Chakraborty, S; Ghose, JC; Mondal, M, 1993)
" Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril."5.07Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991)
"Hydralazine (H) and nitrates (Ns), when combined, reduced morbidity and mortality in some trials of chronic heart failure (CHF)."4.91Hydralazine and nitrates alone or combined for the management of chronic heart failure: A systematic review. ( Clark, AL; Cleland, JG; Farag, M; Mabote, T; Nabhan, AF; Shoaib, A; Zhang, J, 2015)
" The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death."3.96Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020)
" One week after disease induction, animals were randomly assigned to chronic glomerulosclerosis, chronic glomerulosclerosis plus Bay 41-2272 (10 mg/kg body weight/day) or chronic glomerulosclerosis plus hydralazine (15 mg/kg body weight/day)."3.73Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis. ( Kawachi, H; Krämer, S; Kron, S; Loof, T; Martini, S; Neumayer, HH; Peters, H; Shimizu, F; Wang, Y, 2005)
"We evaluated long-term combined vasodilator therapy (hydralazine or ecarazine + isosorbide dinitrate) in 29 patients with chronic congestive heart failure resistant to the optimal conventional therapy."3.67Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response. ( Hatano, M; Hibiya, K; Ichikawa, M; Nagasawa, M; Ozawa, Y; Saito, S; Tamura, Y; Tomobe, K; Yumikura, S, 1984)
"Dihydralazine, sold under the name of Nepressol, is the derivative of the hydrazinophthalazines used in France for the treatment of severe cardiac failure."3.67[Role of dihydralazine in the treatment of chronic cardiac insufficiency]. ( Baudouy, M; Camous, JP; Gibelin, P; Leborgne, L; Morand, P, 1985)
"In rats with large myocardial infarctions, we compared the effects of captopril, a presumed arterial and venous vasodilator, with hydralazine, which is thought primarily to be an arterial vasodilator."3.67Importance of venodilatation in prevention of left ventricular dilatation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine. ( Aguirre, M; Gay, RG; Goldman, S; Raya, TE, 1989)
"The effect of long-term vasodilator therapy (hydralazine, ecarazine or budralazine + isosorbide dinitrate) were evaluated for 20 patients with chronic congestive heart failure due to dilated cardiomyopathy (DCM) resistant to conventional therapy."3.67[Long-term vasodilator therapy of chronic refractory heart failure in patients with dilated cardiomyopathy]. ( Hatano, M; Hibiya, K; Kaseda, N; Moriuchi, M; Ozawa, Y; Saito, S; Tamura, Y; Tokutake, E; Tsuji, M; Yumikura, S, 1986)
"Nine male patients with stable chronic heart failure of different etiology and optimally treated with digoxine and diuretics were given hydralazine, 50 mg b."3.67Improved cardiac performance during exercise following hydralazine treatment in chronic heart failure. ( Conradson, TB; Rydén, L, 1984)
"The haemodynamic effects of oral prazosin and hydralazine were evaluated in patients with refractory heart failure and compared with those of intravenous nitroprusside in the same patients."3.66Comparison of haemodynamic effects of oral prazosin, oral hydralazine, and intravenous nitroprusside in same patients with chronic heart failure. ( Conti, CR; Iacona, M; Mehta, J; Pepine, CJ, 1979)
"To examine the importance of left ventricular chamber size in determing the response to vasodilator therapy, we performed echocardiography in 40 patients with chronic refractory heart failure before they were treated with oral hydralazine."3.66Importance of left ventricular chamber size in determining the response to hydralazine in severe chronic heart failure. ( Gorlin, R; Herman, MV; Medina, N; Meller, J; Packer, M, 1980)
"We studied the effect of vasodilator therapy on renal digoxin clearance in patients with chronic congestive heart failure."3.66Acute vasodilator therapy increases renal clearance of digoxin in patients with congestive heart failure. ( Benowitz, NL; Carlson, CJ; Cogan, JJ; Humphreys, MH; Rapaport, E, 1981)
"Several reports have suggested that because isosorbide dinitrate and hydralazine have different and additive haemodynamic effects at rest in patients with chronic heart failure, these agents should be administered in combination."3.66Vasodilator treatment with isosorbide dinitrate and hydralazine in chronic heart failure. ( Haughom, F; Kramer, B; Massie, BM; Shen, E, 1981)
"Simultaneous hemodynamic and radionuclide angiographic assessment was made at rest and during exercise in nine patients with severe chronic congestive heart failure to determine the value of radionuclide left ventricular ejection fraction measurement in predicting the hemodynamic response to short-term treatment with oral hydralazine."3.66Hydralazine therapy in severe chronic heart failure: inability of radionuclide left ventricular ejection fraction measurement to predict the hemodynamic response. ( Franklin, BA; Goldberg, MJ; Kerin, NZ; Rubenfire, M; Ruskin, R; Willens, HJ, 1983)
"We studied the hemodynamic response to orally administered hydralazine (30 mg) and examined the changes in neurohumoral factors in 16 aged patients with chronic congestive heart failure."3.66Effect of orally administered hydralazine on neurohumoral factors and hemodynamic response in aged patients with chronic congestive heart failure. ( Kuwajima, I; Matsushita, S; Murakami, M; Sakai, M; Ueda, K, 1983)
"In congestive heart failure, acute administration of the converting enzyme inhibitor captopril leads to a decrease in arterial pressure, systemic vascular resistance, left ventricular filling pressure, and the end-diastolic volumes of both ventricles, as well as to an increase in cardiac index, stroke volume index, right and left ventricular ejection fractions."3.66Converting-enzyme inhibitor therapy for chronic heart failure. ( Kramer, BL; Massie, BM; Topic, N, 1983)
" New drugs for the treatment of severe congestive heart failure include dopamine, which has a selective nonadrenergic dilator effect on the renal vascular bed, and dobutamine, which has potent inotropic effects, lowers the left ventricular filling pressure and does not increase the heart rate or the systemic vascular resistance."3.66Contributions of hemodynamic monitoring to the treatment of chronic congestive heart failure. ( Armstrong, PW, 1979)
"17 patients with severe chronic heart failure (class III and IV) were prescribed hydralazine, an arterial vasodilatator, orally at doses of 150 mg to 400 mg/day."3.66[Treatment of severe chronic cardiac insufficiency with dihydralazine. Short-and median-term results]. ( Alison, D; Latour, F; Lavigne, G; Masson, D; Morand, P, 1979)
"The comparative haemodynamic effects of oral prazosin hydrochloride and hydralazine were evaluated in 11 patients with chronic congestive heart failure."3.66Comparison of haemodynamic effects of oral hydralazine and prazosin hydrochloride in patients with chronic congestive heart failure. ( Arnold, S; Brundage, B; Chatterjee, K; Parmley, W; Ports, TA, 1979)
"A patient with severe, chronic congestive heart failure was unresponsive not only to conventional therapy, but also to nonparenteral nitroglycerin and isosorbide dinitrate; he became nitroprusside dependent."3.65Combination vasodilator therapy for severe chronic congestive heart failure. ( Chatterjee, K; Drew, D; Klausner, SC; Parmley, WW; Polansky, J; Zacherle, B, 1976)
"The hemodynamic effects of oral hydralazine were investigated in ten patients (nine in NYHA Class IV and one in Class III) with chronic refractory heart failure."3.65Oral hydralazine therapy for chronic refractory heart failure. ( Chatterjee, K; Greenberg, B; Klausner, S; Massie, B; Norman, A; Parmley, WW; Werner, J, 1976)
"Hydralazine-treated patients also had significant decreases in LV end-diastolic and end-systolic volume indexes, and a significant increase in ejection fraction."2.67Effects of long-term vasodilator therapy on electrocardiographic abnormalities in chronic aortic regurgitation. ( Bristow, JD; Cheitlin, M; Greenberg, B; Jacobson, N; Massie, B; Perlmutter, N; Siemienczuk, D; Szlachcic, J; Wilson, R, 1991)
"Congestive heart failure is accompanied by a number of compensatory mechanisms that may overshoot the mark."2.37Role of isosorbide dinitrate in management of chronic congestive heart failure. ( Parmley, WW, 1985)
"The effect on myocardial function and structure of long-term administration of quinapril (10-20 mg daily), an angiotensin-converting-enzyme (ACE) inhibitor, was investigated in 24 patients (18 men, 6 women; mean age 48 [20-65] years) with chronic isolated asymptomatic aortic or mitral regurgitation."1.29[Long-term treatment with quinapril in chronic aortic and mitral insufficiency]. ( Schömig, A; Schön, HR, 1995)
"In patients with congestive heart failure (CHF), overactivity of the sympathetic nervous system may be accompanied by an impairment of the baroreflex control mechanism."1.28Baroreceptor-mediated release of vasopressin in patients with chronic congestive heart failure and defective sympathetic responsiveness. ( Dietz, R; Kübler, W; Leinberger, H; Manthey, J; Opherk, D; Osterziel, KJ, 1992)
"Prudence is indicated in patients with congestive heart failure due to coronary artery disease."1.27A review of the long-term effects of prazosin and hydralazine in chronic congestive heart failure. ( Rutishauser, W, 1983)
"A total of 127 patients with bronchial asthma of infectious-allergic genesis and chronic obstructive bronchitis were examined for the central and regional hemodynamics as well as for the blood levels of serotonin and monoamine oxidase."1.27[Arterial hypertension in chronic bronchial obstruction and various problems of its treatment]. ( Bobrov, VA; Fushteĭ, IM; Ianushevskaia, TA; Polipova, SN, 1985)
"Symptomatic patients with chronic aortic regurgitation should undergo aortic valve replacement."1.27When to intervene in chronic aortic regurgitation. ( Gaasch, WH; Hoshino, PK, 1986)
"Propranolol was given to 10 hypertensive patients with CGN and hypotensive effect on renal function was observed."1.25Therapy and prognosis of hypertension in chronic nephritis. ( Kajiwara, N, 1975)

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199077 (73.33)18.7374
1990's14 (13.33)18.2507
2000's6 (5.71)29.6817
2010's5 (4.76)24.3611
2020's3 (2.86)2.80

Authors

AuthorsStudies
Kantorowska, A1
Heiselman, CJ1
Halpern, TA1
Akerman, MB1
Elsayad, A1
Muscat, JC1
Sicuranza, GB1
Vintzileos, AM1
Heo, HJ1
Li, Z1
Lindner, DP1
Bishop, NM1
Cipolla, MJ1
Wiggers, H1
Køber, L1
Gislason, G1
Schou, M1
Poulsen, MK1
Vraa, S1
Nielsen, OW1
Bruun, NE1
Nørrelund, H1
Hollingdal, M1
Barasa, A1
Bøttcher, M1
Dodt, K1
Hansen, VB1
Nielsen, G1
Knudsen, AS1
Lomholdt, J1
Mikkelsen, KV1
Jonczy, B1
Brønnum-Schou, J1
Poenaru, MP1
Abdulla, J1
Raymond, I1
Mahboubi, K1
Sillesen, K1
Serup-Hansen, K1
Madsen, JS1
Kristensen, SL1
Larsen, AH1
Bøtker, HE1
Torp-Petersen, C1
Eiskjær, H1
Møller, J1
Hassager, C1
Steffensen, FH1
Bibby, BM1
Refsgaard, J1
Høfsten, DE1
Mellemkjær, S1
Gustafsson, F1
Leavitt, K1
Običan, S1
Yankowitz, J1
Lim, WY1
Woldman, S1
Farag, M1
Mabote, T1
Shoaib, A1
Zhang, J1
Nabhan, AF1
Clark, AL1
Cleland, JG1
Olson-Chen, C1
Seligman, NS1
Leelahavanichkul, A1
Yan, Q1
Hu, X1
Eisner, C1
Huang, Y1
Chen, R1
Mizel, D1
Zhou, H1
Wright, EC1
Kopp, JB1
Schnermann, J1
Yuen, PS1
Star, RA1
Ahmed, A1
Anker, SD1
Negassa, A1
Coats, AJ1
Afzal, R1
Poole-Wilson, PA1
Cohn, JN2
Yusuf, S1
Massie, BM5
Wang, Y1
Krämer, S1
Loof, T1
Martini, S1
Kron, S1
Kawachi, H1
Shimizu, F1
Neumayer, HH1
Peters, H1
Crouch, MA1
Rosen, D1
Decaro, MV1
Graham, MG1
Opie, LH1
Novikov, SV1
Mareev, VIu1
Artese, D1
Albani, A1
Di Tomasso, E1
Mason, DT2
Awan, NA1
Joye, JA1
Lee, G1
DeMaria, AN1
Amsterdam, EA1
Goldberg, MJ1
Franklin, BA1
Rubenfire, M1
Kerin, NZ1
Willens, HJ1
Ruskin, R1
Kramer, BL1
Topic, N1
Schwartz, AB1
Chatterjee, K7
Ueda, K1
Sakai, M1
Matsushita, S1
Kuwajima, I1
Murakami, M1
Satinsky, JD1
Saito, S2
Ichikawa, M1
Ozawa, Y2
Yumikura, S2
Nagasawa, M1
Hibiya, K2
Tamura, Y2
Tomobe, K1
Hatano, M2
Magorien, RD1
Unverferth, DV1
Leier, CV1
Reifart, N1
Kaltenbach, M1
Bussmann, WD1
Conradson, TB2
Rydén, L2
Kothiala, A1
Ramnani, K1
Patel, HR2
Mehta, NC2
Shah, CP2
Eninia, GI1
Smeltere, ES1
Godlevska, MA1
Uzulinia, IP1
Ke, YN2
Parmley, WW4
Rutishauser, W1
Kittleson, MD2
Eyster, GE2
Olivier, NB1
Anderson, LK1
Shvedenko, LA1
Parashchak, AP1
Iurkevich, ST1
Neporadnyĭ, MD1
Bigar', PV1
Fried, R1
Steinherz, LJ1
Levin, AR1
Linday, L1
Tan, CT1
Miller, D1
Rouleau, JL1
Berkowitz, RL2
Packer, M4
Meller, J4
Medina, N3
Yushak, M1
Gorlin, R3
Kramer, B1
Shen, E1
Haughom, F1
Cogan, JJ1
Humphreys, MH1
Carlson, CJ1
Benowitz, NL1
Rapaport, E1
Herman, MV2
Cabaniss, CD1
Greenberg, BH2
DeMots, H1
Murphy, E1
Rahimtoola, S1
Francoual, M1
Nitenberg, A1
Ginks, WR1
Redwood, DR1
Schön, HR1
Schömig, A1
Volkova, LI1
Shteĭngart, IuN1
Lin, M1
Chiang, HT1
Lin, SL1
Chang, MS1
Chiang, BN1
Kuo, HW1
Cheitlin, MD1
Corbalán, R2
Kunstmann, S1
Jalil, J2
Ghose, JC1
Chakraborty, S1
Mondal, M1
Bhandari, B1
Roth, A1
Shotan, A1
Elkayam, U1
Knowlen, GG1
Nachreiner, RF1
Massie, B3
Rubin, S1
Gelberg, H1
Brundage, BH1
Ports, TA2
Morand, P3
Lavigne, G2
Masson, D2
Latour, F2
Alison, D1
Page, A1
Larnaudie, B1
Pic, A1
Videau, P1
Besse, P1
Lloyd, EA1
Curet, LB1
Olson, RW1
Arias, F1
Zamora, J1
Armstrong, PW1
Arnold, S1
Brundage, B1
Parmley, W1
Mehta, J1
Iacona, M1
Pepine, CJ1
Conti, CR1
Velasco, M1
Guevara, J1
Urbina-Quintana, A1
Hernández-Pieretti, O1
Koch-Weser, J1
Drew, D1
Klausner, SC1
Polansky, J1
Zacherle, B1
Greenberg, B2
Werner, J1
Klausner, S1
Norman, A1
Kajiwara, N1
Woods, JR1
Brinkman, CR1
Baumbach, GL1
Heistad, DD1
Manthey, J1
Dietz, R1
Opherk, D1
Osterziel, KJ1
Leinberger, H1
Kübler, W1
Wilson, R1
Perlmutter, N1
Jacobson, N1
Siemienczuk, D1
Szlachcic, J1
Bristow, JD1
Cheitlin, M1
Haeusslein, EA1
Schofield, PM1
Brooks, NH1
Lawrence, GP1
Testa, HJ1
Ward, C1
Johnson, G1
Ziesche, S1
Cobb, F1
Francis, G1
Tristani, F1
Smith, R1
Dunkman, WB1
Loeb, H1
Wong, M1
Zhilin, SV1
Vorob'ev, BI1
Kastanaian, AA1
Masalitinova, IV1
Rahimtoola, SH1
Raya, TE1
Gay, RG1
Aguirre, M1
Goldman, S1
Chervenak, FA1
Dékány, M1
Bányai, F1
Antalóczy, Z1
Moriuchi, M1
Kaseda, N1
Tsuji, M1
Tokutake, E1
Gavrisiuk, VK2
Iakhnitsa, TV2
Feshchenko, IuI1
Roschlau, G1
Hass, S1
Schmehl, V1
Kirichenko, LL1
Gaĭdukova, NI1
Solov'eva, FV1
Thorat, PB1
Patel, KH1
Bobrov, VA2
Fushteĭ, IM2
Polivoda, SN1
Arriagada, D1
Rodríguez, JA1
Chamorro, G1
Meleda, I1
Casanegra, P1
Valenzuela, P1
Polipova, SN1
Ianushevskaia, TA1
Escobar, E1
Thumala, A1
Domenech, R1
Venegas, P1
Hoshino, PK1
Gaasch, WH1
Geggel, RL1
Dozor, AJ1
Fyler, DC1
Reid, LM1
Krzyś, T1
Kalawski, R1
Flaczyński, K1
Lenartowicz, I1
Baudouy, M1
Camous, JP1
Gibelin, P1
Leborgne, L1
Maas, D1
Gilmore, HR1
Loggie, JM1
Ayers, CR1
Harris, RH1
Lefer, LG1
Vertes, V1
Cangiano, JL1
Berman, LB1
Gould, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-blind, Placebo Controlled Study (DANHEART): Hydralazine-ISDN in Patients With Chronic Heart Failure - Hydralazine Heart Failure Trial (H-HeFT) and Metformin in Patients With Chronic Heart Failure and Diabetes or Insulin Resistance - M[NCT03514108]Phase 41,500 participants (Anticipated)Interventional2018-03-01Recruiting
Innovative Strategies for Implementing New CHF Guideline Recommendations[NCT00012974]Phase 1/Phase 260 participants (Anticipated)Interventional2005-11-30Completed
Regional and Systemic Hemodynamic Effects of a Long-term Administration of Amlodipine in Patients With Chronic Heart Failure Treated With a Combination of Enalapril, Furosemide and Digoxin[NCT00151619]Phase 27 participants (Actual)Interventional1999-02-10Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

22 reviews available for hydralazine and Chronic Disease

ArticleYear
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis

2019
Pharmacological management of chronic heart failure: old drugs, new drugs and new indications.
    British journal of hospital medicine (London, England : 2005), 2013, Volume: 74, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2013
Hydralazine and nitrates alone or combined for the management of chronic heart failure: A systematic review.
    International journal of cardiology, 2015, Oct-01, Volume: 196

    Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Humans; Hydralazine; Mortality; Nitrates;

2015
Hypertensive Emergencies in Pregnancy.
    Critical care clinics, 2016, Volume: 32, Issue:1

    Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E

2016
Pharmacotherapy implications of revised chronic heart failure guidelines.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2006, Volume: 21, Issue:7

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
Evidence-based treatment of chronic heart failure.
    Comprehensive therapy, 2007,Spring, Volume: 33, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2007
[Adrenergic alpha-receptor blockaders and direct arteriolar vasodilators in treatment of chronic cardiac insufficiency].
    Terapevticheskii arkhiv, 1983, Volume: 55, Issue:5

    Topics: Adrenergic alpha-Antagonists; Arterioles; Cardiac Output, Low; Chronic Disease; Hemodynamics; Humans

1983
Vasodilator therapy in chronic congestive heart failure.
    Drugs, 1983, Volume: 26, Issue:2

    Topics: Captopril; Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralaz

1983
Vasodilator therapy for chronic heart failure.
    Annual review of pharmacology and toxicology, 1980, Volume: 20

    Topics: Captopril; Chronic Disease; Heart Failure; Hemodynamics; Humans; Hydralazine; Nitrates; Nitroglyceri

1980
Anti-hypertensive drugs in the pregnant patient.
    Obstetrical & gynecological survey, 1980, Volume: 35, Issue:4

    Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide

1980
[Vasodilator agents in chronic heart failure: which is the best option?].
    Revista medica de Chile, 1993, Volume: 121, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Clinical Trials as Topic; Drug Therapy, C

1993
Afterload reduction and cardiac performance. Physiologic basis of systemic vasodilators as a new approach in treatment of congestive heart failure.
    The American journal of medicine, 1978, Volume: 65, Issue:1

    Topics: Aorta; Cardiac Output; Chronic Disease; Heart; Heart Failure; Heart Ventricles; Hemodynamics; Humans

1978
The use of vasodilator agents in the treatment of heart failure.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Nov-10, Volume: 56, Issue:20

    Topics: Cardiac Output; Cardiomegaly; Catheterization; Chronic Disease; Coronary Vessels; Dose-Response Rela

1979
Oral vasodilator therapy for chronic heart failure: a plea for caution.
    The American journal of cardiology, 1978, Volume: 42, Issue:4

    Topics: Cardiac Output; Chronic Disease; Forecasting; Heart Failure; Humans; Hydralazine; Nitrates; Prazosin

1978
Drug therapy. Hydralazine.
    The New England journal of medicine, 1976, 08-05, Volume: 295, Issue:6

    Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Blood Pressure; Cardiac Output; Chronic Disease; Dru

1976
Drug-induced changes in mechanics and structure of cerebral arterioles.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1992, Volume: 10, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Brain; Chronic Disease; Compliance; H

1992
Vasodilator therapy in chronic severe aortic regurgitation.
    Journal of the American College of Cardiology, 1990, Volume: 16, Issue:2

    Topics: Aortic Valve Insufficiency; Chronic Disease; Digitalis Glycosides; Echocardiography; Hemodynamics; H

1990
Hypertension in pregnancy.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Clonidine; Diuretics; Female; Humans; Hydrala

1985
Role of isosorbide dinitrate in management of chronic congestive heart failure.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 2

    Topics: Administration, Oral; Chronic Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug

1985
[Antinuclear factors. Demonstration and clinico-diagnostic significance].
    Medizinische Klinik, 1969, Jul-18, Volume: 64, Issue:29

    Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Chronic Disease

1969
The treatment of chronic hypertension.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Adult; Blood Pressure Determination; Chronic Disease; Diuretics; Female; Ganglionic Blockers; Guanet

1971
Hypertension in children and adolescents. II. Drug therapy.
    The Journal of pediatrics, 1969, Volume: 74, Issue:4

    Topics: Age Factors; Antihypertensive Agents; Blood Pressure Determination; Child; Chlorothiazide; Chronic D

1969

Trials

11 trials available for hydralazine and Chronic Disease

ArticleYear
The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr
    American heart journal, 2021, Volume: 231

    Topics: Aged; Chronic Disease; Denmark; Diabetes Mellitus; Double-Blind Method; Drug Combinations; Female; H

2021
Hydralazine therapy in chronic congestive heart failure. Sustained central and regional hemodynamic responses.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Administration, Oral; Cardiac Output; Chronic Disease; Clinical Trials as Topic; Double-Blind Method

1984
Loss of effectiveness of dihydralazine in the long-term treatment of chronic heart failure.
    European heart journal, 1984, Volume: 5, Issue:7

    Topics: Adult; Aged; Cardiac Output; Chronic Disease; Coronary Circulation; Coronary Disease; Dihydralazine;

1984
Vasodilator therapy in chronic asymptomatic aortic regurgitation: enalapril versus hydralazine therapy.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:4

    Topics: Aged; Aortic Valve Insufficiency; Chronic Disease; Double-Blind Method; Echocardiography; Enalapril;

1994
Effect of vasodilator therapy on mortality in chronic congestive heart failure.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:5

    Topics: Adult; Aged; Captopril; Chi-Square Distribution; Chronic Disease; Double-Blind Method; Drug Therapy,

1993
A randomized comparison between the hemodynamic effects of hydralazine and nitroglycerin alone and in combination at rest and during isometric exercise in patients with chronic mitral regurgitation.
    American heart journal, 1993, Volume: 125, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Chronic Disease; Drug Therapy, Combination; Exercise;

1993
Effects of long-term vasodilator therapy on electrocardiographic abnormalities in chronic aortic regurgitation.
    The American journal of cardiology, 1991, Oct-01, Volume: 68, Issue:9

    Topics: Adult; Aortic Valve Insufficiency; Cardiac Volume; Chronic Disease; Double-Blind Method; Electrocard

1991
Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Chronic Disease; Coronary Disease; Exercise Test; F

1991
A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure.
    The New England journal of medicine, 1991, Aug-01, Volume: 325, Issue:5

    Topics: Adolescent; Adult; Aged; Chronic Disease; Death, Sudden; Double-Blind Method; Drug Administration Sc

1991
[Differential use of peripheral vasodilators in the treatment of chronic circulatory failure in patients with mitral valve insufficiency].
    Kardiologiia, 1990, Volume: 30, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Heart Failure; Hemodynamics; Humans; Hydralazine;

1990
Comparative study on the short-term effects of angiotensin converting enzyme inhibitors (Lopirin, SQUIBB and Tensiomin), and dihydralazine in chronic cardiac failure.
    Acta physiologica Hungarica, 1988, Volume: 72 Suppl

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cardiac Output, Lo

1988

Other Studies

72 other studies available for hydralazine and Chronic Disease

ArticleYear
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents;

2020
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compound

2020
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
    Kidney international, 2010, Volume: 78, Issue:11

    Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens

2010
American College of Cardiology/American Heart Association Chronic Heart Failure Evaluation and Management guidelines: relevance to the geriatric practice.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Echoca

2003
Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study.
    Lancet (London, England), 2003, Mar-29, Volume: 361, Issue:9363

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Data Interpretation, Statistical; D

2003
The year in heart failure: 2004.
    Journal of cardiac failure, 2005, Volume: 11, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Defibrillator

2005
Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis.
    Kidney international, 2005, Volume: 68, Issue:1

    Topics: Animals; Biomarkers; Blood Pressure; Body Weight; Chronic Disease; Disease Progression; Eating; Enzy

2005
Drugs and the heart. VI. Vasodilating drugs.
    Lancet (London, England), 1980, May-03, Volume: 1, Issue:8175

    Topics: Cardiotonic Agents; Chronic Disease; Heart Failure; Hemodynamics; Humans; Hydralazine; Hypertension;

1980
[Vasodilator drugs in the therapy of chronic congestive heart failure. Clinico-case contribution].
    Minerva medica, 1983, Mar-31, Volume: 74, Issue:13

    Topics: Blood Pressure; Cardiomegaly; Chronic Disease; Drug Evaluation; Heart; Heart Failure; Humans; Hydral

1983
Treatment of acute and chronic congestive heart failure by vasodilator-afterload reduction.
    Archives of internal medicine, 1980, Volume: 140, Issue:12

    Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Cardiac Output; Chronic Disease; Diastole; H

1980
Hydralazine therapy in severe chronic heart failure: inability of radionuclide left ventricular ejection fraction measurement to predict the hemodynamic response.
    Journal of the American College of Cardiology, 1983, Volume: 2, Issue:5

    Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output; Chronic Disease; Drug Evaluation; Female; Hear

1983
Converting-enzyme inhibitor therapy for chronic heart failure.
    Herz, 1983, Volume: 8, Issue:2

    Topics: Captopril; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Heart Fai

1983
Effect of orally administered hydralazine on neurohumoral factors and hemodynamic response in aged patients with chronic congestive heart failure.
    Japanese heart journal, 1983, Volume: 24, Issue:5

    Topics: Administration, Oral; Aged; Aldosterone; Chronic Disease; Epinephrine; Female; Heart Failure; Hemody

1983
Chronic heart failure in the elderly: vasodilator therapy.
    Angiology, 1983, Volume: 34, Issue:8

    Topics: Aged; Blood Pressure; Chronic Disease; Female; Follow-Up Studies; Heart Failure; Humans; Hydralazine

1983
Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response.
    Japanese circulation journal, 1984, Volume: 48, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Cardiac Catheterization; Cardiomyopathy, Dilated; Chronic Disease; Dru

1984
[Hydralazine in chronic heart failure].
    Lakartidningen, 1984, Sep-19, Volume: 81, Issue:38

    Topics: Chronic Disease; Heart Failure; Hemodynamics; Humans; Hydralazine

1984
Improved cardiac performance during exercise following hydralazine treatment in chronic heart failure.
    Acta medica Scandinavica, 1984, Volume: 216, Issue:1

    Topics: Aged; Chronic Disease; Digoxin; Diuretics; Exercise Test; Heart Failure; Hemodynamics; Humans; Hydra

1984
Adjuvant therapy of chronic refractory cardiac failure with oral hydralazine and isosorbide dinitrate.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Chronic Disease; Digoxin; Diuretics; Drug Therapy, Co

1983
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
    Klinicheskaia meditsina, 1984, Volume: 62, Issue:3

    Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disea

1984
[The changes in plasma catecholamine and hemodynamics in the treatment of chronic congestive heart failure with hydralazine].
    Zhonghua xin xue guan bing za zhi, 1984, Volume: 12, Issue:1

    Topics: Adult; Aged; Catecholamines; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Hydralazi

1984
A review of the long-term effects of prazosin and hydralazine in chronic congestive heart failure.
    European heart journal, 1983, Volume: 4 Suppl A

    Topics: Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Heart Failure; Humans; Hydralazine; N

1983
Oral hydralazine therapy for chronic mitral regurgitation in the dog.
    Journal of the American Veterinary Medical Association, 1983, Jun-01, Volume: 182, Issue:11

    Topics: Administration, Oral; Animals; Cardiac Output; Chronic Disease; Dog Diseases; Dogs; Female; Heart Ra

1983
[Changes in the hemodynamic indices of hypertension patients].
    Vrachebnoe delo, 1983, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Drug Evaluation; Female; H

1983
Use of hydralazine for intractable cardiac failure in childhood.
    The Journal of pediatrics, 1980, Volume: 97, Issue:6

    Topics: Antineoplastic Agents; Child; Chronic Disease; Female; Heart Failure; Humans; Hydralazine; Maxillary

1980
Hydralazine in chronic CHF.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 652

    Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com

1981
Hemodynamic characterization of tolerance to long-term hydralazine therapy in severe chronic heart failure.
    The New England journal of medicine, 1982, Jan-14, Volume: 306, Issue:2

    Topics: Adult; Blood Pressure; Chronic Disease; Drug Tolerance; Female; Heart Failure; Heart Rate; Hemodynam

1982
Vasodilator treatment with isosorbide dinitrate and hydralazine in chronic heart failure.
    British heart journal, 1981, Volume: 45, Issue:4

    Topics: Adult; Aged; Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydral

1981
Acute vasodilator therapy increases renal clearance of digoxin in patients with congestive heart failure.
    Circulation, 1981, Volume: 64, Issue:5

    Topics: Chronic Disease; Digoxin; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Humans; Hydralazi

1981
Dose requirements of hydralazine in patients with severe chronic congestive heart failure.
    The American journal of cardiology, 1980, Volume: 45, Issue:3

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Dose-Response Relationship, Drug; Female; Heart Failur

1980
Vasodilator therapy of chronic congestive heart failure.
    Journal of the Medical Association of Georgia, 1980, Volume: 69, Issue:2

    Topics: Ambulatory Care; Chronic Disease; Heart Failure; Humans; Hydralazine; Nitrates; Prazosin; Quinazolin

1980
Beneficial effects of hydralazine on rest and exercise hemodynamics in patients with chronic severe aortic insufficiency.
    Circulation, 1980, Volume: 62, Issue:1

    Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Chronic Disease; Exercise Test; Female; Hea

1980
Importance of left ventricular chamber size in determining the response to hydralazine in severe chronic heart failure.
    The New England journal of medicine, 1980, Jul-31, Volume: 303, Issue:5

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Volume; Chronic Disease; Echocardiography

1980
[Alteration in left ventricular function induced by dihydralazine in severe chronic congestive heart failure: limits of vasodilator therapy? (author's transl)].
    La Nouvelle presse medicale, 1980, Apr-26, Volume: 9, Issue:19

    Topics: Chronic Disease; Dihydralazine; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hydralazine

1980
Haemodynamic effects of hydralazine at rest and during exercise in patients with chronic heart failure.
    British heart journal, 1980, Volume: 44, Issue:3

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Hydralazi

1980
[Long-term treatment with quinapril in chronic aortic and mitral insufficiency].
    Deutsche medizinische Wochenschrift (1946), 1995, Mar-31, Volume: 120, Issue:13

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease;

1995
[Individual approach to vasodilator treatment of pulmonary hypertension in chronic bronchitis].
    Klinicheskaia meditsina, 1994, Volume: 72, Issue:6

    Topics: Adult; Aminophylline; Bronchitis; Chronic Disease; Humans; Hydralazine; Hypertension, Pulmonary; Mid

1994
Comparison of plasma aldosterone concentration among clinical status groups of dogs with chronic heart failure.
    Journal of the American Veterinary Medical Association, 1983, Nov-01, Volume: 183, Issue:9

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril;

1983
Long-term outpatient vasodilator therapy of congestive heart failure. Consideration of agents at rest and during exercise.
    The American journal of medicine, 1978, Volume: 65, Issue:1

    Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Heart Ventricles; Hemodynamics; Humans; H

1978
[Treatment of severe chronic cardiac insufficiency with dihydralazine. Short-and median-term results].
    Archives des maladies du coeur et des vaisseaux, 1979, Volume: 72, Issue:3

    Topics: Administration, Oral; Adult; Aged; Chronic Disease; Dihydralazine; Drug Evaluation; Female; Heart Fa

1979
[Hemodynamic effects of oral dihydralazine and sublingual isosorbide dinitrate, alone and in combination in chronic heart failure].
    Archives des maladies du coeur et des vaisseaux, 1979, Volume: 72, Issue:12

    Topics: Administration, Oral; Aged; Chronic Disease; Dihydralazine; Drug Therapy, Combination; Female; Heart

1979
Evaluation of a program of bed rest in the treatment of chronic hypertension in pregnancy.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:3

    Topics: Bed Rest; Birth Weight; Chronic Disease; Female; Fetal Death; Humans; Hydralazine; Hypertension; Inf

1979
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:4

    Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Hu

1979
Contributions of hemodynamic monitoring to the treatment of chronic congestive heart failure.
    Canadian Medical Association journal, 1979, Oct-06, Volume: 121, Issue:7

    Topics: Chronic Disease; Dobutamine; Dopamine; Heart; Heart Failure; Hemodynamics; Humans; Hydralazine; Moni

1979
Comparison of haemodynamic effects of oral hydralazine and prazosin hydrochloride in patients with chronic congestive heart failure.
    British heart journal, 1979, Volume: 42, Issue:6

    Topics: Adult; Aged; Cardiac Output; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Hydralazi

1979
Comparison of haemodynamic effects of oral prazosin, oral hydralazine, and intravenous nitroprusside in same patients with chronic heart failure.
    British heart journal, 1979, Volume: 42, Issue:6

    Topics: Adult; Aged; Chronic Disease; Ferricyanides; Heart Failure; Hemodynamics; Humans; Hydralazine; Male;

1979
Combined clonidine and hydralazine therapy in severe and refractory hypertension.
    Acta cientifica venezolana, 1977, Volume: 28, Issue:5

    Topics: Adult; Blood Pressure; Chronic Disease; Clonidine; Drug Evaluation; Drug Therapy, Combination; Femal

1977
[The treatment of severe chronic cardiac failure by dihydralazine].
    La Nouvelle presse medicale, 1978, Dec-23, Volume: 7, Issue:46

    Topics: Adult; Aged; Chronic Disease; Dihydralazine; Heart Diseases; Humans; Hydralazine; Male; Middle Aged

1978
Combination vasodilator therapy for severe chronic congestive heart failure.
    Annals of internal medicine, 1976, Volume: 85, Issue:4

    Topics: Chronic Disease; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosor

1976
Oral hydralazine therapy for chronic refractory heart failure.
    Circulation, 1976, Volume: 54, Issue:6

    Topics: Adult; Aged; Blood Pressure; Capillaries; Chronic Disease; Female; Heart Failure; Heart Rate; Hemody

1976
Therapy and prognosis of hypertension in chronic nephritis.
    Japanese circulation journal, 1975, Volume: 39, Issue:7

    Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extra

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
Baroreceptor-mediated release of vasopressin in patients with chronic congestive heart failure and defective sympathetic responsiveness.
    The American journal of cardiology, 1992, Jul-15, Volume: 70, Issue:2

    Topics: Adult; Aged; Cardiac Catheterization; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans;

1992
Does the magnitude of mitral regurgitation determine hemodynamic response to vasodilation in chronic congestive heart failure?
    Chest, 1991, Volume: 100, Issue:5

    Topics: Adult; Aged; Chronic Disease; Heart Failure; Heart Valve Prosthesis; Hemodynamics; Humans; Hydralazi

1991
Importance of venodilatation in prevention of left ventricular dilatation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine.
    Circulation research, 1989, Volume: 64, Issue:2

    Topics: Animals; Blood Volume; Captopril; Chronic Disease; Heart; Heart Ventricles; Hydralazine; Male; Myoca

1989
[Long-term vasodilator therapy of chronic refractory heart failure in patients with dilated cardiomyopathy].
    Journal of cardiography. Supplement, 1986, Issue:9

    Topics: Adult; Aged; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Echocardiography;

1986
[Effect of hydralazine on bronchial patency and blood gas composition in patients with chronic obstructive bronchitis].
    Vrachebnoe delo, 1987, Issue:12

    Topics: Adult; Bronchi; Bronchitis; Carbon Dioxide; Chronic Disease; Female; Humans; Hydralazine; Male; Midd

1987
[Effect of hydralazine on the respiratory function of the lungs and blood gas composition in patients with chronic obstructive bronchitis].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:8

    Topics: Adult; Airway Obstruction; Bronchitis; Bronchodilator Agents; Carbon Dioxide; Chronic Disease; Femal

1988
[Chronic drug-induced hepatitis caused by dihydralazine].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1988, Volume: 48, Issue:1

    Topics: Aged; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; Dihydralazine; Female

1988
[Effects of hydralazine therapy in patients with chronic congestive heart failure].
    Zhonghua nei ke za zhi, 1987, Volume: 26, Issue:3

    Topics: Adult; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Male; Middle Aged;

1987
[Effect of peripheral vasodilators on thrombocyte aggregation in chronic circulatory insufficiency].
    Sovetskaia meditsina, 1986, Issue:2

    Topics: Adult; Aged; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydralazine;

1986
Comparative efficacy of digoxin, hydralazine and combination therapy in chronic congestive heart failure.
    The Journal of the Association of Physicians of India, 1986, Volume: 34, Issue:6

    Topics: Adult; Chronic Disease; Digoxin; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydralazi

1986
[Regional hemodynamic function in chronic obstructive bronchitis with arterial hypertension].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:12

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bronchitis; Chronic Disease; Female; Hemodynamics;

1986
[Long-term effects of digoxin and hydralazine in patients with chronic cardiac insufficiency].
    Revista medica de Chile, 1985, Volume: 113, Issue:10

    Topics: Adult; Aged; Chronic Disease; Digoxin; Drug Administration Schedule; Drug Therapy, Combination; Fema

1985
[Arterial hypertension in chronic bronchial obstruction and various problems of its treatment].
    Kardiologiia, 1985, Volume: 25, Issue:6

    Topics: Adult; Asthma; Bronchitis; Chronic Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans;

1985
[Vasodilator agents in chronic asymptomatic aortic insufficiency: echocardiographic study].
    Revista medica de Chile, 1985, Volume: 113, Issue:8

    Topics: Adult; Aged; Aortic Valve Insufficiency; Captopril; Chronic Disease; Echocardiography; Female; Hemod

1985
When to intervene in chronic aortic regurgitation.
    Archives of internal medicine, 1986, Volume: 146, Issue:2

    Topics: Aortic Valve Insufficiency; Chronic Disease; Echocardiography; Heart Ventricles; Humans; Hydralazine

1986
Effect of vasodilators at rest and during exercise in young adults with cystic fibrosis and chronic cor pulmonale.
    The American review of respiratory disease, 1985, Volume: 131, Issue:4

    Topics: Adult; Chronic Disease; Cystic Fibrosis; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; M

1985
[Combined use of isoprenaline and hydralazine in the treatment of chronic circulatory insufficiency].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Jan-15, Volume: 38, Issue:2

    Topics: Adult; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; H

1985
[Role of dihydralazine in the treatment of chronic cardiac insufficiency].
    Annales de medecine interne, 1985, Volume: 136, Issue:3

    Topics: Aged; Arterioles; Cardiac Output; Chronic Disease; Dihydralazine; Follow-Up Studies; Heart Failure;

1985
Refractory hypertension.
    Lancet (London, England), 1973, Sep-01, Volume: 2, Issue:7827

    Topics: Administration, Oral; Antihypertensive Agents; Chronic Disease; Diazoxide; Drug Combinations; Drug R

1973
Control of renin release in experimental hypertension.
    Circulation research, 1969, Volume: 24, Issue:5 Suppl

    Topics: Acetylcholine; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Catheterization; Chronic Dise

1969
Hypertension in end-stage renal disease.
    The New England journal of medicine, 1969, May-01, Volume: 280, Issue:18

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Chronic

1969