hydralazine has been researched along with Cardiovascular Diseases in 19 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydralazine was administered to cohorts of 4 patients at the following dose levels: I) 50 mg/day, II) 75 mg/day, III) 100 mg/day and IV) 150 mg/day." | 2.71 | A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes. ( Angeles, E; Cabrera, G; Cetina, L; Chanona-Vilchis, J; Chavez-Blanco, A; Duenas-González, A; Perez-Cardenas, E; Revilla-Vazquez, A; Sandoval, K; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C; Zambrano, P, 2005) |
| "Hydralazine pretreatment reversed DE-induced TF, tPA, TNF-α, and MMP-2 expression but not eNOS, RAGE, and HMGB-1." | 1.39 | Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention. ( Andrews, D; Bass, V; Gilmour, MI; King, C; Kodavanti, UP; Krantz, QT; Ledbetter, AD; Nyska, A; Richards, JE; Schladweiler, MC; Thomas, RF, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kodavanti, UP | 1 |
| Thomas, RF | 1 |
| Ledbetter, AD | 1 |
| Schladweiler, MC | 1 |
| Bass, V | 1 |
| Krantz, QT | 1 |
| King, C | 1 |
| Nyska, A | 1 |
| Richards, JE | 1 |
| Andrews, D | 1 |
| Gilmour, MI | 1 |
| Burgueño, AL | 1 |
| Gianotti, TF | 1 |
| Mansilla, NG | 1 |
| Pirola, CJ | 1 |
| Sookoian, S | 1 |
| POLAK, F | 1 |
| MENCIK, Z | 1 |
| HUEGIN, W | 1 |
| TAKATSU, T | 1 |
| Zambrano, P | 1 |
| Segura-Pacheco, B | 1 |
| Perez-Cardenas, E | 1 |
| Cetina, L | 1 |
| Revilla-Vazquez, A | 1 |
| Taja-Chayeb, L | 1 |
| Chavez-Blanco, A | 1 |
| Angeles, E | 1 |
| Cabrera, G | 1 |
| Sandoval, K | 1 |
| Trejo-Becerril, C | 1 |
| Chanona-Vilchis, J | 1 |
| Duenas-González, A | 1 |
| Baumann, M | 1 |
| Janssen, BJ | 1 |
| Hermans, JJ | 1 |
| Peutz-Kootstra, C | 1 |
| Witzke, O | 1 |
| Smits, JF | 1 |
| Struijker Boudier, HA | 1 |
| Hoenig, MR | 1 |
| Bianchi, C | 1 |
| Sellke, FW | 1 |
| Kataoka, C | 1 |
| Egashira, K | 1 |
| Inoue, S | 1 |
| Takemoto, M | 1 |
| Ni, W | 1 |
| Koyanagi, M | 1 |
| Kitamoto, S | 1 |
| Usui, M | 1 |
| Kaibuchi, K | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Wilhelmsen, L | 1 |
| Berglund, G | 1 |
| Sannerstedt, R | 1 |
| Hansson, L | 1 |
| Andersson, O | 1 |
| Sievertsson, R | 1 |
| Wikstrand, J | 1 |
| Taguchi, J | 2 |
| Freis, ED | 4 |
| Danilevicius, Z | 1 |
| Franks, PJ | 1 |
| Hartley, K | 1 |
| Bulpitt, PF | 1 |
| Bulpitt, CJ | 1 |
| Sorkin, EM | 1 |
| Clissold, SP | 1 |
| Brogden, RN | 1 |
| Almeyda, J | 1 |
| Levantine, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Phase III Clinical Trial: Evaluation of the Combination of TRANSKRIP ® Plus Carboplatin and Paclitaxel as First Line Chemotherapy on Survival of Patients With Recurrent - Persistent Cervical Cancer"[NCT02446652] | Phase 3 | 230 participants (Anticipated) | Interventional | 2015-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for hydralazine and Cardiovascular Diseases
| Article | Year |
|---|---|
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
[DRUG THERAPY OF CIRCULATORY DISEASES].
Topics: Antihypertensive Agents; Arteriosclerosis; Bretylium Compounds; Cardiovascular Diseases; Chlorothiaz | 1964 |
Hypoxia inducible factor-1 alpha, endothelial progenitor cells, monocytes, cardiovascular risk, wound healing, cobalt and hydralazine: a unifying hypothesis.
Topics: Angiogenic Proteins; Animals; Cardiovascular Agents; Cardiovascular Diseases; Cell Hypoxia; Cell Mov | 2008 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Cutaneous reactions to cardiovascular drugs.
Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Debrisoquin; Digitalis Glycosides; | 1973 |
The treatment of hypertension. Why, when and how.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyd | 1972 |
4 trials available for hydralazine and Cardiovascular Diseases
| Article | Year |
|---|---|
A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes.
Topics: 5-Methylcytosine; Adult; Aged; Binding Sites; Biopsy; Cardiovascular Diseases; Cohort Studies; Cytos | 2005 |
Partial versus complete control of blood pressure in the prevention of hypertensive complications.
Topics: Atrial Fibrillation; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-Up St | 1975 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Partial reduction of blood pressure and prevention of complications in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-U | 1974 |
10 other studies available for hydralazine and Cardiovascular Diseases
| Article | Year |
|---|---|
Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention.
Topics: Albumins; Animals; Atherosclerosis; Cardiovascular Diseases; Hydralazine; Hypertension; Lung Disease | 2013 |
Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Blotting, Western; Cardiovascular Diseases; Die | 2013 |
[Content of isolated & combined short-term reserpine & dihydrazinophthalazine administration in circulatory hypertensive diseases].
Topics: Cardiovascular Diseases; Combined Modality Therapy; Hydralazine; Hypertension; Manipulation, Osteopa | 1958 |
Transient AT1 receptor-inhibition in prehypertensive spontaneously hypertensive rats results in maintained cardiac protection until advanced age.
Topics: Age Factors; Aging; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; C | 2007 |
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Topics: Actins; Amides; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases | 2002 |
Effect of treatment of hypertension in the primary preventive trial, Göteborg, Sweden.
Topics: Adrenergic beta-Antagonists; Bethanidine; Cardiovascular Diseases; Cerebrovascular Disorders; Corona | 1979 |
Editorial: Hypertension is worth treating.
Topics: Blood Pressure; Cardiovascular Diseases; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide | 1975 |
Risk of serious morbidity associated with hydralazine versus methyldopa treatment in hypertensive patients.
Topics: Cardiovascular Diseases; Female; Humans; Hydralazine; Hypertension; Kidney Diseases; Male; Medical R | 1991 |
Results of treatment of hypertension.
Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Hum | 1971 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |