Page last updated: 2024-10-28

hydralazine and Cardiomyopathy, Dilated

hydralazine has been researched along with Cardiomyopathy, Dilated in 15 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.

Research Excerpts

ExcerptRelevanceReference
" Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril."9.07Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991)
"The mechanism by which hydralazine improves cardiac function in patients with heart failure is not well characterized."7.67Effects of hydralazine on pressure-volume and stress-volume relations in congestive heart failure secondary to idiopathic dilated cardiomyopathy. ( Lipscomb, KM; Sanford, CF; Smucker, ML, 1985)
" Fifty patients with symptoms due to chronic heart failure despite diuretic therapy were randomised to receive additional treatment with either hydralazine or captopril."5.07Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine. ( Brooks, NH; Lawrence, GP; Schofield, PM; Testa, HJ; Ward, C, 1991)
"We evaluated long-term combined vasodilator therapy (hydralazine or ecarazine + isosorbide dinitrate) in 29 patients with chronic congestive heart failure resistant to the optimal conventional therapy."3.67Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response. ( Hatano, M; Hibiya, K; Ichikawa, M; Nagasawa, M; Ozawa, Y; Saito, S; Tamura, Y; Tomobe, K; Yumikura, S, 1984)
"The effect of long-term vasodilator therapy (hydralazine, ecarazine or budralazine + isosorbide dinitrate) were evaluated for 20 patients with chronic congestive heart failure due to dilated cardiomyopathy (DCM) resistant to conventional therapy."3.67[Long-term vasodilator therapy of chronic refractory heart failure in patients with dilated cardiomyopathy]. ( Hatano, M; Hibiya, K; Kaseda, N; Moriuchi, M; Ozawa, Y; Saito, S; Tamura, Y; Tokutake, E; Tsuji, M; Yumikura, S, 1986)
"The mechanism by which hydralazine improves cardiac function in patients with heart failure is not well characterized."3.67Effects of hydralazine on pressure-volume and stress-volume relations in congestive heart failure secondary to idiopathic dilated cardiomyopathy. ( Lipscomb, KM; Sanford, CF; Smucker, ML, 1985)
"Heart failure is an established predictor of primary cardiac events during pregnancy."1.40Treatment of pre-existing cardiomyopathy during pregnancy. ( Ascoop, AK; De Backer, J; De Pauw, M; Gevaert, S; Roelens, K; Tromp, F, 2014)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gevaert, S1
De Pauw, M1
Tromp, F1
Ascoop, AK1
Roelens, K1
De Backer, J1
Gori, T1
Münzel, T1
Kopecky, SL1
Litin, SC1
Saito, S2
Ichikawa, M1
Ozawa, Y2
Yumikura, S2
Nagasawa, M1
Hibiya, K2
Tamura, Y2
Tomobe, K1
Hatano, M2
Martins, S1
do Rosário, L1
Soares, RM1
Sequeira, A1
Sousa, MJ1
Sousa, L1
Oliveira, M1
Ferreira, R1
Branco, L1
Ferreira, L1
Ramos, S1
Antunes, AM1
Schofield, PM1
Brooks, NH1
Lawrence, GP1
Testa, HJ1
Ward, C1
Schofer, J2
Mathey, DG1
Polster, J1
Bode, V1
Dietlein, G1
Ktsoeva, TV1
Moriuchi, M1
Kaseda, N1
Tsuji, M1
Tokutake, E1
Bleifeld, W1
Chopra, A1
Chib, P1
Singh, RP1
Prabhakaran, SN1
Dighero, H1
Zepeda, F1
Gómez, G1
Ruksin, VV1
Krzyś, T1
Kalawski, R1
Flaczyński, K1
Lenartowicz, I1
Smucker, ML1
Sanford, CF1
Lipscomb, KM1

Trials

3 trials available for hydralazine and Cardiomyopathy, Dilated

ArticleYear
Which vasodilator drug in patients with chronic heart failure? A randomised comparison of captopril and hydralazine.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Chronic Disease; Coronary Disease; Exercise Test; F

1991
Hemodynamic and neurohumoral response to hydralazine versus captopril: a controlled study in idiopathic dilated cardiomyopathy.
    Journal of cardiovascular pharmacology, 1987, Volume: 9 Suppl 2

    Topics: Adult; Captopril; Cardiomyopathy, Dilated; Clinical Trials as Topic; Female; Hemodynamics; Humans; H

1987
[Effect of long-term hydralazine in dilated myocardiopathies].
    Revista medica de Chile, 1985, Volume: 113, Issue:9

    Topics: Administration, Oral; Adult; Cardiomyopathy, Dilated; Clinical Trials as Topic; Female; Hemodynamics

1985

Other Studies

12 other studies available for hydralazine and Cardiomyopathy, Dilated

ArticleYear
Treatment of pre-existing cardiomyopathy during pregnancy.
    Acta cardiologica, 2014, Volume: 69, Issue:2

    Topics: Adult; Antihypertensive Agents; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Heart Failure; H

2014
Symptomatic and hemodynamic benefit of pentaerythrityl tetranitrate and hydralazine in a case of congestive heart failure.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2009, Volume: 98, Issue:10

    Topics: Aged; Cardiomyopathy, Dilated; Drug Therapy, Combination; Dyspnea; Heart Failure; Hemodynamics; Huma

2009
Clinical pearls in cardiology.
    Mayo Clinic proceedings, 2010, Volume: 85, Issue:5

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cardiomyopathy, Dilated; Diuretics; Female; Heart Failure

2010
Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response.
    Japanese circulation journal, 1984, Volume: 48, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Cardiac Catheterization; Cardiomyopathy, Dilated; Chronic Disease; Dru

1984
[The influence of therapy (sympathomimetic amines versus vasodilators) in the indexes of ejection fraction derived from an analysis of Doppler aortic flow].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1998, Volume: 17, Issue:6

    Topics: Captopril; Cardiomyopathy, Dilated; Dobutamine; Dopamine; Echocardiography, Doppler; Female; Humans;

1998
[Role of vasodilator agents in the complex treatment of circulatory insufficiency in patients with ischemic heart disease].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:5

    Topics: Aged; Blood Pressure; Blood Volume; Cardiomyopathy, Dilated; Coronary Disease; Delayed-Action Prepar

1986
[Long-term vasodilator therapy of chronic refractory heart failure in patients with dilated cardiomyopathy].
    Journal of cardiography. Supplement, 1986, Issue:9

    Topics: Adult; Aged; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Echocardiography;

1986
Sympathetic activity in idiopathic dilated cardiomyopathy. Influence of captopril and hydralazine.
    Cardiovascular drugs and therapy, 1987, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Captopril; Cardiomyopathy, Dilated; Catecholamines; Female; Humans; Hydralazine;

1987
Beta-blockade-vasodilator therapy in peripartum cardiomyopathy.
    The Journal of the Association of Physicians of India, 1986, Volume: 34, Issue:7

    Topics: Adolescent; Cardiomyopathy, Dilated; Female; Humans; Hydralazine; Pregnancy; Propranolol

1986
[Peripheral vasodilator in cardiac insufficiency in the acute period of myocardial infarction].
    Sovetskaia meditsina, 1985, Issue:2

    Topics: Cardiomyopathy, Dilated; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine

1985
[Combined use of isoprenaline and hydralazine in the treatment of chronic circulatory insufficiency].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Jan-15, Volume: 38, Issue:2

    Topics: Adult; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; H

1985
Effects of hydralazine on pressure-volume and stress-volume relations in congestive heart failure secondary to idiopathic dilated cardiomyopathy.
    The American journal of cardiology, 1985, Oct-01, Volume: 56, Issue:10

    Topics: Adult; Aged; Cardiomyopathy, Dilated; Heart; Heart Failure; Hemodynamics; Humans; Hydralazine; Middl

1985