Compounds > hydralazine
Page last updated: 2024-10-28

hydralazine and Cardiac Diseases

hydralazine has been researched along with Cardiac Diseases in 30 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
" Similarly, chronic congestive heart failure patients, irrespective of the etiology, improve hemodynamically after an infusion of phentolamine, nitroprusside or hydralazine."3.66Electrophysiologic properties of hydralazine in man. ( Becker, WH; Gould, L; Reddy, CV; Singh, BK; Zen, B, 1980)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199022 (73.33)18.7374
1990's2 (6.67)18.2507
2000's3 (10.00)29.6817
2010's3 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leelahavanichkul, A1
Yan, Q1
Hu, X1
Eisner, C1
Huang, Y1
Chen, R1
Mizel, D1
Zhou, H1
Wright, EC1
Kopp, JB1
Schnermann, J1
Yuen, PS1
Star, RA1
Nako, H1
Kataoka, K1
Koibuchi, N1
Dong, YF1
Toyama, K1
Yamamoto, E1
Yasuda, O1
Ichijo, H1
Ogawa, H1
Kim-Mitsuyama, S1
Collier, R1
AITCHISON, JD1
CRANSTON, WI1
PRIEST, EA1
SAMBHI, MP1
VENNING, EH1
BECK, JC1
WEAVER, KH1
SMITH, WM1
DAMATO, AN1
GALLUZZI, NJ1
GARFIELD, CF1
HANOWELL, EG1
STIMSON, WH1
THURM, RH1
WALSH, JJ1
BROMER, L1
Duster, T1
Margolis, KL1
Piller, LB1
Ford, CE1
Henriquez, MA1
Cushman, WC1
Einhorn, PT1
Colon, PJ1
Vidt, DG1
Christian, R1
Wong, ND1
Wright, JT1
Goff, DC1
Kahn, J1
Siegel, M1
Lee, SL1
Peress, NS1
Gould, L1
Reddy, CV1
Zen, B1
Singh, BK1
Becker, WH1
Hilliker, KS1
Roth, RA1
Artman, M2
Parrish, MD1
Graham, TP2
Blackwell, JN1
Castell, DO1
Jensen, T1
Kornerup, HJ1
Lederballe, O1
Videbaek, J1
Henningsen, P1
Francoual, M1
Nitenberg, A1
Rodrigues, B1
Grassby, PF1
Battell, ML1
Lee, SY1
McNeill, JH1
Knowlen, GG1
Kittleson, MD1
Nachreiner, RF1
Eyster, GE1
Schrey, A1
Becker, CE1
Benowitz, NL1
Drózdz, M1
Kucharz, E1
Wieczorek, M1
Buch, J1
Morand, P1
Lavigne, G1
Masson, D1
Latour, F1
Hanton, G1
Longeart, L1
Lodola, A1
Guyatt, GH1
Lauk, S1
Trott, KR1
Jasmin, G1
Slany, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000542]Phase 30 participants Interventional1993-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydralazine and Cardiac Diseases

ArticleYear
Congestive heart failure in childhood and adolescence: recognition and management.
    American heart journal, 1983, Volume: 105, Issue:3

    Topics: Adolescent; Captopril; Cardiomyopathies; Child; Digoxin; Dobutamine; Dopamine; Echocardiography; Ele

1983
The treatment of heart failure. A methodological review of the literature.
    Drugs, 1986, Volume: 32, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Digoxi

1986
[Cardiac complications in hypertension].
    Wiener klinische Wochenschrift, 1972, May-05, Volume: 84, Issue:18

    Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Diseas

1972

Trials

3 trials available for hydralazine and Cardiac Diseases

ArticleYear
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal

2007
Treatment with hydralazine in mild to moderate mitral or aortic incompetence.
    European heart journal, 1983, Volume: 4, Issue:5

    Topics: Adult; Aged; Aortic Valve; Blood Pressure; Female; Heart Diseases; Heart Rate; Heart Ventricles; Hem

1983
The treatment of heart failure. A methodological review of the literature.
    Drugs, 1986, Volume: 32, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Digoxi

1986

Other Studies

25 other studies available for hydralazine and Cardiac Diseases

ArticleYear
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
    Kidney international, 2010, Volume: 78, Issue:11

    Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens

2010
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blo

2012
A race-based detour to personalized medicine.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2012, Apr-17, Volume: 184, Issue:7

    Topics: Black People; Genetics, Medical; Heart Diseases; Humans; Hydralazine; Isosorbide Dinitrate; Pharmaco

2012
The effects of 1-hydrazinophthalazine on the pulmonary circulation in mitral disease.
    British heart journal, 1955, Volume: 17, Issue:4

    Topics: Disease; Heart Diseases; Heart Valve Diseases; Hydralazine; Lung; Mitral Valve; Pulmonary Circulatio

1955
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine;

1964
THE HEART AND ACUTE GLOMERULONEPHRITIS.
    Maryland state medical journal, 1964, Volume: 13

    Topics: Child; Diet, Sodium-Restricted; Digitalis Glycosides; Drug Therapy; Glomerulonephritis; Heart Diseas

1964
THE EVALUATION OF ANTIHYPERTENSIVE THERAPY COOPERATIVE CLINICAL TRIAL METHOD. I. DOUBLE-BLIND CONTROL COMPARISON OF CHLOROTHIAZIDE, RAUWOLFIA SERPENTINA, AND HYDRALAZINE.
    Annals of internal medicine, 1964, Volume: 61

    Topics: Antihypertensive Agents; Biomedical Research; Chlorothiazide; Double-Blind Method; Drug Therapy; Hea

1964
Medicine. Race and reification in science.
    Science (New York, N.Y.), 2005, Feb-18, Volume: 307, Issue:5712

    Topics: Bias; Cardiovascular Agents; Crime; Databases, Nucleic Acid; Drug Combinations; Forensic Sciences; G

2005
Race in a bottle. Drugmakers are eager to develop medicines targeted at ethnic groups, but so far they have made poor choices based on unsound science.
    Scientific American, 2007, Volume: 297, Issue:2

    Topics: Black or African American; Drug Combinations; Drug Design; Ethnicity; Heart Diseases; Heart Failure;

2007
The epidemiology of drug-induced systemic lupus erythematosus.
    Arthritis and rheumatism, 1967, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension;

1967
Electrophysiologic properties of hydralazine in man.
    Pacing and clinical electrophysiology : PACE, 1980, Volume: 3, Issue:5

    Topics: Aged; Bundle of His; Electrophysiology; Female; Heart Conduction System; Heart Diseases; Heart Failu

1980
Alteration of monocrotaline pyrrole-induced cardiopulmonary effects in rats by hydrallazine, dexamethasone or sulphinpyrazone.
    British journal of pharmacology, 1984, Volume: 82, Issue:2

    Topics: Animals; Body Weight; Cardiomegaly; Dexamethasone; Heart Diseases; Hydralazine; L-Lactate Dehydrogen

1984
Oesophageal chest pain: a point of view.
    Gut, 1984, Volume: 25, Issue:1

    Topics: Calcium Channel Blockers; Diagnosis, Differential; Esophageal Diseases; Heart Diseases; Humans; Hydr

1984
[Alteration in left ventricular function induced by dihydralazine in severe chronic congestive heart failure: limits of vasodilator therapy? (author's transl)].
    La Nouvelle presse medicale, 1980, Apr-26, Volume: 9, Issue:19

    Topics: Chronic Disease; Dihydralazine; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hydralazine

1980
Hypertriglyceridemia in experimental diabetes: relationship to cardiac dysfunction.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Glucose; Cholesterol; Clofibrate; Diabetes Mellitus, Experim

1994
Comparison of plasma aldosterone concentration among clinical status groups of dogs with chronic heart failure.
    Journal of the American Veterinary Medical Association, 1983, Nov-01, Volume: 183, Issue:9

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril;

1983
[New nitrate indications].
    Advances in clinical pharmacology, 1978, Volume: 17

    Topics: Dihydralazine; Drug Combinations; Heart Diseases; Humans; Hydralazine; Isosorbide Dinitrate; Myocard

1978
Hypertensive emergencies.
    The Medical clinics of North America, 1979, Volume: 63, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases

1979
Morphological changes observed after stimulation or inhibition of adrenic system in rats chronically treated with hydrazinophtalazines.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:6

    Topics: Animals; Catecholamines; Epinephrine; Heart; Heart Diseases; Hemorrhage; Hydralazine; Inflammation;

1979
[Vasodilation treatment of heart insufficiency].
    Ugeskrift for laeger, 1978, May-15, Volume: 140, Issue:20

    Topics: Heart Diseases; Humans; Hydralazine; Nitrites; Nitroprusside; Phentolamine; Prazosin; Vasodilator Ag

1978
[The treatment of severe chronic cardiac failure by dihydralazine].
    La Nouvelle presse medicale, 1978, Dec-23, Volume: 7, Issue:46

    Topics: Adult; Aged; Chronic Disease; Dihydralazine; Heart Diseases; Humans; Hydralazine; Male; Middle Aged

1978
Cardiotoxicity of hydralazine and minoxidil in the rat. Influence of age.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 71, Issue:2

    Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Rate; Hydralazine; Isoproterenol; Minoxidil; M

1991
Guidelines for vasodilator therapy of congestive heart failure in infants and children.
    American heart journal, 1987, Volume: 113, Issue:4

    Topics: Captopril; Child; Child, Preschool; Enalapril; Heart Diseases; Heart Failure; Heart Ventricles; Hemo

1987
Radiation induced heart disease in hypertensive rats.
    International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:1

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Radiation; Heart; Heart Diseases; Hydralazine;

1988
Factors influencing the production of cardiomyopathies by methoxamine and metaraminol.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Aortic Aneurysm; Blood Pressure; Diet; Edema; F

1969