hydralazine has been researched along with Cancer of Colon in 8 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied the influence of the peripheral vasodilator hydralazine (HDZ) on the vasculature and blood perfusion of two members of a series of subcutaneous murine adenocarcinomata of the colon (MAC tumours), and the influence of HDZ on the efficacy and/or toxicity of TCNU and melphalan." | 3.68 | The influence of hydralazine on the vasculature, blood perfusion and chemosensitivity of MAC tumours. ( Bibby, MC; Cox, JA; Crawford, SM; Quinn, PK, 1992) |
| "Hydralazine treatment markedly reduced (99m)Tc-MIBI and (201)Tl accumulation in LS180 xenografts; moreover, intratumoural pO(2) decreased from 14." | 1.31 | Hypoxia-induced alteration of tracer accumulation in cultured cancer cells and xenografts in mice: implications for pre-therapeutic prediction of treatment outcomes with (99m)Tc-sestamibi, (201)Tl chloride and (99m)Tc-HL91. ( Bai, J; Bunko, H; Kinuya, S; Li, XF; Michigishi, T; Shuke, N; Takayama, T; Tonami, N; Watanabe, N; Yokoyama, K, 2002) |
| "Hydralazine and isoniazid were also tested by the subcutaneous (sc) route at weekly dosages of 17 and 83 mg/kg, respectively, in both intact and partially hepatectomized rats, but many succumbed after 7 to 49 weeks of treatment." | 1.28 | Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats. ( Gershbein, LL; Rao, KC, 1992) |
| "When hydralazine was given 40 min after a dose of 800 mg/kg of MISO, without X-rays, growth delays in excess of 5 tumour volume doubling times resulted and fewer tumour cells were present in histological sections." | 1.28 | Manipulation of oxygenation in a human tumour xenograft with BW12C or hydralazine: effects on responses to radiation and to the bioreductive cytotoxicity of misonidazole or RSU-1069. ( Cole, S; Robbins, L, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinuya, S | 1 |
| Yokoyama, K | 1 |
| Li, XF | 1 |
| Bai, J | 1 |
| Watanabe, N | 1 |
| Shuke, N | 1 |
| Takayama, T | 1 |
| Bunko, H | 1 |
| Michigishi, T | 1 |
| Tonami, N | 1 |
| Cowen, SE | 1 |
| Bibby, MC | 2 |
| Double, JA | 1 |
| Zlotecki, RA | 1 |
| Baxter, LT | 1 |
| Boucher, Y | 1 |
| Jain, RK | 1 |
| Quinn, PK | 1 |
| Cox, JA | 1 |
| Crawford, SM | 1 |
| Gershbein, LL | 1 |
| Rao, KC | 1 |
| Bremner, JC | 1 |
| Counsell, CJ | 1 |
| Adams, GE | 1 |
| Stratford, IJ | 1 |
| Wood, PJ | 1 |
| Dunn, JF | 1 |
| Radda, GK | 1 |
| Cole, S | 1 |
| Robbins, L | 1 |
| Kaufman, DW | 1 |
| Kelly, JP | 1 |
| Rosenberg, L | 1 |
| Stolley, PD | 1 |
| Warshauer, ME | 1 |
| Shapiro, S | 1 |
8 other studies available for hydralazine and Cancer of Colon
| Article | Year |
|---|---|
Hypoxia-induced alteration of tracer accumulation in cultured cancer cells and xenografts in mice: implications for pre-therapeutic prediction of treatment outcomes with (99m)Tc-sestamibi, (201)Tl chloride and (99m)Tc-HL91.
Topics: Animals; Cell Hypoxia; Colonic Neoplasms; Female; Humans; Hydralazine; Mice; Mice, Inbred BALB C; Mi | 2002 |
Characterisation of the vasculature within a murine adenocarcinoma growing in different sites to evaluate the potential of vascular therapies.
Topics: Adenocarcinoma; Animals; Benzimidazoles; Cecal Neoplasms; Colonic Neoplasms; Fluorescent Dyes; Human | 1995 |
Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation.
Topics: Angiotensin II; Animals; Colonic Neoplasms; Epinephrine; Extracellular Space; Female; Humans; Hydral | 1995 |
The influence of hydralazine on the vasculature, blood perfusion and chemosensitivity of MAC tumours.
Topics: Adenocarcinoma; Animals; Bone Marrow; Cell Division; Cell Line; Colonic Neoplasms; Hydralazine; Male | 1992 |
Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms | 1992 |
In vivo 31P nuclear magnetic resonance spectroscopy of experimental murine tumours and human tumour xenografts: effects of blood flow modification.
Topics: Animals; Colonic Neoplasms; Humans; Hydralazine; Magnetic Resonance Spectroscopy; Melanoma, Experime | 1991 |
Manipulation of oxygenation in a human tumour xenograft with BW12C or hydralazine: effects on responses to radiation and to the bioreductive cytotoxicity of misonidazole or RSU-1069.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzaldehydes; Colonic Neop | 1989 |
Hydralazine use in relation to cancers of the lung, colon, and rectum.
Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Hydralazine; Lung Neoplasms; Male; Middle Aged; Rect | 1989 |