hydralazine has been researched along with Brain Ischemia in 10 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 7.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| " Oral nifedipine is now considered an alternative first-line therapy, along with intravenous hydralazine and labetalol for women presenting with pre-eclampsia." | 4.98 | Focused Update on Pharmacologic Management of Hypertensive Emergencies. ( Broscious, R; Devabhakthuni, S; Noel, ZR; Watson, K, 2018) |
| "Results suggest that perfusion can be augmented in ischemic stroke with norepinephrine and hydralazine." | 4.31 | Augmentation of perfusion with simultaneous vasodilator and inotropic agents in experimental acute middle cerebral artery occlusion: a pilot study. ( Carroll, T; Christoforidis, GA; Jeong, YI; Liu, M; Niekrasz, M; Roth, S; Saadat, N, 2023) |
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 3.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| "Antihypertensive treatment with hydralazine for 10 weeks but not 6 weeks reduces infarct size in 13-week-old spontaneously hypertensive rats subjected to focal cerebral ischemia." | 3.68 | Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats. ( Slivka, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, M | 1 |
| Saadat, N | 1 |
| Jeong, YI | 1 |
| Roth, S | 1 |
| Niekrasz, M | 1 |
| Carroll, T | 1 |
| Christoforidis, GA | 1 |
| Watson, K | 1 |
| Broscious, R | 1 |
| Devabhakthuni, S | 1 |
| Noel, ZR | 1 |
| McKay, C | 1 |
| Hall, AB | 1 |
| Cortes, J | 1 |
| Elewa, HF | 1 |
| Kozak, A | 1 |
| Johnson, MH | 1 |
| Ergul, A | 1 |
| Fagan, SC | 1 |
| Slivka, A | 1 |
| Bednar, MM | 1 |
| Gross, CE | 1 |
| Howard, DB | 1 |
| Russell, SR | 1 |
| Ellenberger, C | 1 |
| Tamaki, K | 1 |
| Fujishima, M | 1 |
| Nakatomi, Y | 1 |
| Ishitsuka, T | 1 |
| Ogata, J | 1 |
| Omae, T | 1 |
| Bentahila, S | 1 |
| Atkinson, J | 1 |
| Capdeville, C | 1 |
| Tanaka, S | 1 |
| Ashida, S | 1 |
| Akashi, A | 1 |
1 review available for hydralazine and Brain Ischemia
| Article | Year |
|---|---|
Focused Update on Pharmacologic Management of Hypertensive Emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Emergencies; Enalapri | 2018 |
1 trial available for hydralazine and Brain Ischemia
| Article | Year |
|---|---|
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; | 1983 |
8 other studies available for hydralazine and Brain Ischemia
| Article | Year |
|---|---|
Augmentation of perfusion with simultaneous vasodilator and inotropic agents in experimental acute middle cerebral artery occlusion: a pilot study.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Dogs; Hydralazine; Infarction, Middle Cerebral | 2023 |
Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Female; Fib | 2015 |
Blood pressure lowering after experimental cerebral ischemia provides neurovascular protection.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Are | 2007 |
Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats.
Topics: Age Factors; Animals; Blood Pressure; Brain Ischemia; Drug Administration Schedule; Hydralazine; Hyp | 1993 |
The effect of vasodilators on aspirin-induced antagonism of t-PA thrombolysis.
Topics: Animals; Antihypertensive Agents; Aspirin; Atenolol; Brain Ischemia; Cerebrovascular Circulation; Dr | 2001 |
Effects of long-term antihypertensive treatment on brain metabolism after bilateral carotid artery occlusion in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain; Brain Ischemia; Carbon Dioxide; Energy Metab | 1979 |
Protective effects of antihypertensive treatment with isradipine on the consequences of cerebral ischaemia in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Brain Ischemia; Hydralazine; Hypertension; Isradipine; Male; Motor | 1991 |
Effects of antihypertensive drugs on experimental cerebral ischemia in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Brain Chemistry; Brain Ischemia; Carotid A | 1990 |