hydralazine has been researched along with Brain Hemorrhage, Cerebral in 13 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a single-center, retrospective chart review of individuals diagnosed with spontaneous intracerebral hemorrhage (ICH) receiving labetalol, hydralazine, and/or nicardipine within 24 h of hospital admission to assess the primary endpoint of BPV, defined as the standard deviation of systolic BP, with labetalol and/or hydralazine compared to nicardipine ± labetalol and/or hydralazine." | 7.91 | Nicardipine Reduces Blood Pressure Variability After Spontaneous Intracerebral Hemorrhage. ( Dierkhising, RA; Kuper, PJ; Mara, KC; Poyant, JO; Rabinstein, AA; Ritchie, BM; Wijdicks, EFM, 2019) |
| " The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 7.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
| "We conducted a single-center, retrospective chart review of individuals diagnosed with spontaneous intracerebral hemorrhage (ICH) receiving labetalol, hydralazine, and/or nicardipine within 24 h of hospital admission to assess the primary endpoint of BPV, defined as the standard deviation of systolic BP, with labetalol and/or hydralazine compared to nicardipine ± labetalol and/or hydralazine." | 3.91 | Nicardipine Reduces Blood Pressure Variability After Spontaneous Intracerebral Hemorrhage. ( Dierkhising, RA; Kuper, PJ; Mara, KC; Poyant, JO; Rabinstein, AA; Ritchie, BM; Wijdicks, EFM, 2019) |
| " The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 3.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
| " Initial dosing with nicardipine lowered acute diastolic BP than labetalol (least square mean difference (labetalol-nicardipine)=5." | 3.11 | Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage. ( Behymer, TP; Bettin, M; Christianson, T; Coleman, ER; Divani, A; Flaherty, ML; Gilkerson, LA; James, ML; King, NKK; Krishnamoorthy, V; Langefeld, CD; McCauley, JL; Ng, Y; Qi, W; Shah, S; Testai, FD; Walsh, KB; Woo, D, 2022) |
| "Blood pressure (BP) reduction after intracerebral hemorrhage (ICH) is controversial, because of concerns that this may cause critical reductions in perihematoma perfusion and thereby precipitate tissue damage." | 2.79 | Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study. ( Buck, BH; Butcher, KS; Choi, V; Coutts, SB; Demchuk, AM; Dowlatshahi, D; Emery, DJ; Gould, BE; Hansen, MB; Hill, MD; Kate, MP; McCourt, R; Mouridsen, K; Østergaard, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Ng, Y | 1 |
| Qi, W | 1 |
| King, NKK | 1 |
| Christianson, T | 1 |
| Krishnamoorthy, V | 1 |
| Shah, S | 1 |
| Divani, A | 1 |
| Bettin, M | 1 |
| Coleman, ER | 1 |
| Flaherty, ML | 1 |
| Walsh, KB | 1 |
| Testai, FD | 1 |
| McCauley, JL | 1 |
| Gilkerson, LA | 1 |
| Langefeld, CD | 1 |
| Behymer, TP | 1 |
| Woo, D | 1 |
| James, ML | 1 |
| Poyant, JO | 1 |
| Kuper, PJ | 1 |
| Mara, KC | 1 |
| Dierkhising, RA | 1 |
| Rabinstein, AA | 1 |
| Wijdicks, EFM | 1 |
| Ritchie, BM | 1 |
| Kate, MP | 1 |
| Hansen, MB | 1 |
| Mouridsen, K | 1 |
| Østergaard, L | 1 |
| Choi, V | 1 |
| Gould, BE | 1 |
| McCourt, R | 1 |
| Hill, MD | 1 |
| Demchuk, AM | 1 |
| Coutts, SB | 1 |
| Dowlatshahi, D | 1 |
| Emery, DJ | 1 |
| Buck, BH | 1 |
| Butcher, KS | 1 |
| TAKEUCHI, J | 1 |
| TAKEDA, T | 1 |
| UCHIDA, E | 1 |
| OKADA, R | 1 |
| SHINTANI, F | 1 |
| WERKOE, L | 1 |
| Smeda, J | 1 |
| Vasdev, S | 1 |
| King, SR | 1 |
| Tejima, E | 1 |
| Katayama, Y | 1 |
| Suzuki, Y | 1 |
| Kano, T | 1 |
| Lo, EH | 1 |
| Romankiewicz, JA | 1 |
| Derham, RJ | 1 |
| Hawkins, DF | 1 |
| De Vries, LS | 1 |
| Aber, VR | 1 |
| Elder, MG | 1 |
| Freis, ED | 1 |
| Bock, KD | 1 |
| Milhorat, TH | 1 |
| Kojimahara, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)[NCT01202864] | 6,000 participants (Actual) | Observational | 2010-08-01 | Completed | |||
| Clinical Study of the Safety and Efficacy of Analgesia-first Minimal Sedation as an Early Antihypertensive Treatment for Spontaneous Intracerebral Hemorrhage[NCT03207100] | 338 participants (Actual) | Interventional | 2017-12-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydralazine and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Pharmacology and clinical use of drugs in hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox | 1977 |
2 trials available for hydralazine and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage.
Topics: Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Humans; Hydralazine; Hypertension; Lab | 2022 |
Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Female; Hematoma; Humans; Hydral | 2014 |
10 other studies available for hydralazine and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Nicardipine Reduces Blood Pressure Variability After Spontaneous Intracerebral Hemorrhage.
Topics: Administration, Intravenous; Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrha | 2019 |
Vascular lesions in experimental renal hypertension, with special reference to effect of hypotensive treatment.
Topics: Arteries; Cerebral Hemorrhage; Coronary Vessels; Guanethidine; Humans; Hydralazine; Hydrochlorothiaz | 1963 |
[HYPERTENSION].
Topics: Cerebral Hemorrhage; Diuretics; Ganglionic Blockers; Heart Arrest; Hydralazine; Hypertension; Kidney | 1963 |
Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Captopril; | 1999 |
Hemorrhagic transformation after fibrinolysis with tissue plasminogen activator: evaluation of role of hypertension with rat thromboembolic stroke model.
Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Brain; Cerebral Hemorrhage; Cerebr | 2001 |
Outcome of pregnancies complicated by severe hypertension and delivered before 34 weeks; stepwise logistic regression analysis of prognostic factors.
Topics: Adult; Birth Weight; Cerebral Hemorrhage; Cesarean Section; Female; Fetal Growth Retardation; Gestat | 1989 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
[What is reliable in the therapy of hypertension?].
Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health | 1970 |
Intracerebral hemorrhage, acute hydrocephalus, and systemic hypertension.
Topics: Arteriovenous Malformations; Carotid Arteries; Cerebral Hemorrhage; Cerebral Ventriculography; Cereb | 1971 |
Healing and exacerbation of arterial lesions in rats with experimental hypertension, with special reference to effects of antihypertensive drugs on arterial lesions.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Cerebral Arteries; Cerebral Hemorrhage; | 1967 |