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hydralazine and Bradyarrhythmia

hydralazine has been researched along with Bradyarrhythmia in 16 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Research Excerpts

ExcerptRelevanceReference
"In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)."9.04[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978)
"To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy."8.82Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003)
"The positive chronotropic effect of hydralazine was studied in 9 patients with symptomatic sinus bradycardia."7.67Chronotropic effect of hydralazine and its mechanism of symptomatic sinus bradycardia. ( Halon, DA; Lewis, BS; Merdler, A; Rodeanu, ME; Rozenman, Y; Shefer, A, 1987)
"Hydralazine (Apresoline) was used to increase heart rate in 21 patients (14 hypertensive and 7 normotensive) suffering from symptomatic sinus bradycardia (SSB)."7.66Hydralazine in the management of symptomatic sinus bradycardia. ( Gotsman, MS; Lewis, BS; Rod, JL; Weiss, AT, 1981)
"In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)."5.04[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978)
"To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy."4.82Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003)
"Hydralazine (H) induces hypotension accompanied by cardiac stimulation due to activation of the arterial baroreflex."3.69Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats. ( Vidrio, H, 1996)
"The positive chronotropic effect of hydralazine was studied in 9 patients with symptomatic sinus bradycardia."3.67Chronotropic effect of hydralazine and its mechanism of symptomatic sinus bradycardia. ( Halon, DA; Lewis, BS; Merdler, A; Rodeanu, ME; Rozenman, Y; Shefer, A, 1987)
"Hydralazine (Apresoline) was used to increase heart rate in 21 patients (14 hypertensive and 7 normotensive) suffering from symptomatic sinus bradycardia (SSB)."3.66Hydralazine in the management of symptomatic sinus bradycardia. ( Gotsman, MS; Lewis, BS; Rod, JL; Weiss, AT, 1981)
"Since 1955 standardized treatment applied uniformly to all cases of eclampsia at Parkland Memorial Hospital has consisted of (1) magnesium sulfate intravenously and intramuscularly to control convulsions, (2) intravenous hydralazine intermittently to lower diastolic blood pressure when it exceeded 110 mm."3.65Standardized treatment of 154 consecutive cases of eclampsia. ( Pritchard, JA; Pritchard, SA, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sánchez-Salvatori, MA1
Vidrio, H2
Magee, LA1
Cham, C1
Waterman, EJ1
Ohlsson, A1
von Dadelszen, P1
Wehner, RJ1
Romanauskas, VS1
Krug, H1
Dziamski, R1
Piszczek, I1
Głuszek, J1
Been, M1
de Bono, DP1
Miller, HC1
Hillis, WS1
Weiss, AT1
Rod, JL1
Gotsman, MS1
Lewis, BS2
Mizroch, S1
Yurasek, M1
Ebel, H1
Lübke, H1
Klaus, D1
Zehner, J1
Witzgall, H1
Nakao, K1
Kato, H1
Takagi, K1
Mauro, B1
Savagnone, E1
Pritchard, JA1
Pritchard, SA1
Rozenman, Y1
Merdler, A1
Rodeanu, ME1
Shefer, A1
Halon, DA1
Belic, N1
Talano, JV1
Hoobler, SW1
Sagastume, E1
Ingenito, AJ1
Barrett, JP1
Procita, L1

Reviews

1 review available for hydralazine and Bradyarrhythmia

ArticleYear
Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis.
    BMJ (Clinical research ed.), 2003, Oct-25, Volume: 327, Issue:7421

    Topics: Antihypertensive Agents; Blood Pressure; Bradycardia; Female; Heart Rate, Fetal; Humans; Hydralazine

2003

Trials

3 trials available for hydralazine and Bradyarrhythmia

ArticleYear
[Dihydralazine in the treatment of bradycardia in the sick sinus syndrome].
    Kardiologia polska, 1984, Volume: 27, Issue:4

    Topics: Adult; Aged; Bradycardia; Clinical Trials as Topic; Dihydralazine; Female; Heart Rate; Humans; Hydra

1984
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Oct-20, Volume: 103, Issue:42

    Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydroch

1978
Clonidine hydrochloride in the treatment of hypertension.
    The American journal of cardiology, 1971, Volume: 28, Issue:1

    Topics: Antihypertensive Agents; Bradycardia; Central Nervous System; Chlorides; Diuretics; Drug Synergism;

1971

Other Studies

12 other studies available for hydralazine and Bradyarrhythmia

ArticleYear
Reflex bradycardia induced by hydralazine in sino-aortic deafferented conscious rats.
    Autonomic & autacoid pharmacology, 2003, Volume: 23, Issue:1

    Topics: Animals; Aorta; Baroreflex; Blood Pressure; Bradycardia; Carotid Sinus; Consciousness; Denervation;

2003
An adverse reaction with hydralazine: a case study.
    AANA journal, 1981, Volume: 49, Issue:3

    Topics: Blood Pressure; Bradycardia; Brain Neoplasms; Frontal Lobe; Glioblastoma; Humans; Hydralazine; Injec

1981
Effect of afterload reduction in patients with ventricular and physiological pacing.
    British heart journal, 1984, Volume: 51, Issue:3

    Topics: Adult; Aged; Blood Pressure; Bradycardia; Cardiac Output; Cardiac Pacing, Artificial; Female; Heart;

1984
Hydralazine in the management of symptomatic sinus bradycardia.
    European journal of cardiology, 1981, Volume: 12, Issue:5

    Topics: Adult; Aged; Blood Pressure; Bradycardia; Female; Heart Rate; Humans; Hydralazine; Male; Middle Aged

1981
Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats.
    Archives of medical research, 1996,Autumn, Volume: 27, Issue:3

    Topics: Animals; Antihypertensive Agents; Baroreflex; Bradycardia; Female; Heart Rate; Hydralazine; Hyperten

1996
Hypotension and bradycardia following diazoxide and hydralazine therapy.
    JAMA, 1977, Jun-06, Volume: 237, Issue:23

    Topics: Bradycardia; Diazoxide; Humans; Hydralazine; Hypertension; Hypotension; Male; Middle Aged

1977
Proceedings: Effects of prolonged oral administration of hydralazine on reflex bradycardia in conscious spontaneously hypertensive rats.
    Japanese heart journal, 1976, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Bradycardia; Disease Models, Animal; Hydralazine; Hypertension; Press

1976
[Clinical considerations on a group of patients with arterial hypertension treated with propranolol].
    Bollettino della Societa italiana di cardiologia, 1976, Volume: 21, Issue:7

    Topics: Bradycardia; Diuretics; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Propranolol

1976
Standardized treatment of 154 consecutive cases of eclampsia.
    American journal of obstetrics and gynecology, 1975, Nov-01, Volume: 123, Issue:5

    Topics: Abruptio Placentae; Anesthesia; Bradycardia; Delivery, Obstetric; Diuretics; Eclampsia; Female; Feta

1975
Chronotropic effect of hydralazine and its mechanism of symptomatic sinus bradycardia.
    The American journal of cardiology, 1987, Jan-01, Volume: 59, Issue:1

    Topics: Aged; Aged, 80 and over; Arrhythmia, Sinus; Autonomic Nerve Block; Biomechanical Phenomena; Bradycar

1987
Current concepts in sick sinus syndrome. II. ECG manifestation and diagnostic and therapeutic approaches.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Atrial Fibrillation; Atropine; Bradycardia; Cardiac Pacing, Artificial; Electric Stimulation; Electr

1985
Centrally mediated peripheral hypotensive effects of reserpine and hydralazine when perfused through the isolated in situ cat brain.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Bradycardia; Brain; Brain Chemistry; Carotid Sinus; Ca

1969