hydralazine has been researched along with Blood Pressure, Low in 78 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both intravenous hydralazine and oral nifedipine are equally effective in lowering of blood pressure in acute hypertensive emergency of pregnancy." | 9.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "We previously reported that the fixed-dose combination of isosorbide dinitrate and hydralazine hydrochloride (FDC I/H) significantly decreased the risk of all-cause death and first hospitalization for heart failure (HF) and improved quality of life in patients with New York Heart Association class III or IV heart failure in the African-American Heart Failure Trial (A-HeFT)." | 9.12 | Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial. ( Adams, K; Carson, P; Cohn, JN; Ferdinand, K; Ofili, E; Olukotun, AY; Sabolinski, ML; Tam, SW; Taylor, AL; Taylor, M; Worcel, M; Yancy, CW; Ziesche, S, 2007) |
| "To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia." | 8.31 | Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023) |
| "Our previous studies showed that chronic ethanol feeding attenuates centrally (clonidine) evoked and potentiates peripherally (hydralazine) evoked hypotension in female rats." | 7.77 | Bradykinin B2 receptor-dependent enhancement of enalapril-evoked hypotension in ethanol-fed female rats. ( Abdel-Rahman, AA; El-Mas, MM, 2011) |
| " Hydralazine (HDZ)-induced hypotension activates NK3R expressed by magnocellular neurons, increases plasma VP and OT levels, and induces c-Fos expression in VP and OT neurons." | 7.74 | Blockade of NK3R signaling in the PVN decreases vasopressin and oxytocin release and c-Fos expression in the magnocellular neurons in response to hypotension. ( Flynn, FW; Haley, GE, 2008) |
| "This study sought to assess the effect of baseline systolic blood pressure (SBP) and changes in SBP on the effectiveness of treatment with fixed-dose combination of isosorbide dinitrate and hydralazine (FDC I/H) in patients with heart failure (HF)." | 7.74 | Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial. ( Adams, KF; Anand, IS; Archambault, WT; Cohn, JN; Olukotun, AY; Rector, TS; Sabolinski, ML; Tam, SW; Taylor, AL; Worcel, M, 2007) |
| "Clonidine (a mixed alpha2-adrenoceptor and imidazoline I1 receptor agonist)-evoked hypotension was associated with dissimilar reductions in c-jun gene expression in the rostral ventrolateral medulla (RVLM) and the nucleus tractus solitarius (NTS) in normotensive rats." | 7.73 | Site-dependent inhibition of neuronal c-jun in the brainstem elicited by imidazoline I1 receptor activation: role in rilmenidine-evoked hypotension. ( Abdel-Rahman, AA; Li, G; Wang, X, 2005) |
| "Previous experiments have indicated that arterial hypotension increases plasma oxytocin (OT) levels in rats and that OT infused intravenously causes an increase in plasma renin activity (PRA)." | 7.71 | Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats. ( Huang, W; Sjöquist, M; Skott, O; Stricker, EM; Sved, AF, 2001) |
| "The oral angiotensin-converting enzyme inhibitor captopril (CPT) produces beneficial hemodynamic and clinical responses in patients with chronic congestive heart failure (CHF)." | 7.66 | Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982) |
| "The hemodynamic benefits and safety of combined therapy with captopril and hydralazine were studied during invasive hemodynamic monitoring in 14 patients with severe heart failure." | 7.66 | Hemodynamic responses to combined therapy with captopril and hydralazine in patients with severe heart failure. ( Combs, DT; Hanlon, JT; Massie, BM; Packer, M, 1983) |
| "Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats." | 5.25 | Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975) |
| "Both intravenous hydralazine and oral nifedipine are equally effective in lowering of blood pressure in acute hypertensive emergency of pregnancy." | 5.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "We previously reported that the fixed-dose combination of isosorbide dinitrate and hydralazine hydrochloride (FDC I/H) significantly decreased the risk of all-cause death and first hospitalization for heart failure (HF) and improved quality of life in patients with New York Heart Association class III or IV heart failure in the African-American Heart Failure Trial (A-HeFT)." | 5.12 | Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial. ( Adams, K; Carson, P; Cohn, JN; Ferdinand, K; Ofili, E; Olukotun, AY; Sabolinski, ML; Tam, SW; Taylor, AL; Taylor, M; Worcel, M; Yancy, CW; Ziesche, S, 2007) |
| " Glyceryl trinitrate and labetalol were associated with fewer incidences of tachycardia and palpitation respectively than hydralazine." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| "To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia." | 4.31 | Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023) |
| "To determine whether the incidence of hypotension or adverse fetal heart tracing (FHT) category change differed following antepartum administration of intravenous (IV) labetalol versus hydralazine." | 3.83 | Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low. ( Aghajanian, P; Greene, N; Kilpatrick, SJ; Rodriguez, M; Sharma, KJ, 2016) |
| "Our previous studies showed that chronic ethanol feeding attenuates centrally (clonidine) evoked and potentiates peripherally (hydralazine) evoked hypotension in female rats." | 3.77 | Bradykinin B2 receptor-dependent enhancement of enalapril-evoked hypotension in ethanol-fed female rats. ( Abdel-Rahman, AA; El-Mas, MM, 2011) |
| " Hydralazine (HDZ)-induced hypotension activates NK3R expressed by magnocellular neurons, increases plasma VP and OT levels, and induces c-Fos expression in VP and OT neurons." | 3.74 | Blockade of NK3R signaling in the PVN decreases vasopressin and oxytocin release and c-Fos expression in the magnocellular neurons in response to hypotension. ( Flynn, FW; Haley, GE, 2008) |
| "Activation of the neurokinin 3 receptor (NK3R) by a receptor agonist, hypotension, and hyperosmolarity results in the internalization of NK3R expressed by magnocellular neurons and the release of vasopressin (VP) and oxytocin (OT) into the circulation." | 3.74 | Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge. ( Flynn, FW; Haley, GE, 2007) |
| "This study sought to assess the effect of baseline systolic blood pressure (SBP) and changes in SBP on the effectiveness of treatment with fixed-dose combination of isosorbide dinitrate and hydralazine (FDC I/H) in patients with heart failure (HF)." | 3.74 | Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial. ( Adams, KF; Anand, IS; Archambault, WT; Cohn, JN; Olukotun, AY; Rector, TS; Sabolinski, ML; Tam, SW; Taylor, AL; Worcel, M, 2007) |
| "Clonidine (a mixed alpha2-adrenoceptor and imidazoline I1 receptor agonist)-evoked hypotension was associated with dissimilar reductions in c-jun gene expression in the rostral ventrolateral medulla (RVLM) and the nucleus tractus solitarius (NTS) in normotensive rats." | 3.73 | Site-dependent inhibition of neuronal c-jun in the brainstem elicited by imidazoline I1 receptor activation: role in rilmenidine-evoked hypotension. ( Abdel-Rahman, AA; Li, G; Wang, X, 2005) |
| " Because SP stimulates vasopressin (VP) and oxytocin release from explants of the hypothalamo-neurohypophyseal system (HNS), two hypotheses were tested: (1) SP-stimulated VP release is mediated by NK3-Rs, and (2) stimulation of the A1 pathway by hypotension activates SON NK3-Rs." | 3.72 | Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons. ( Howe, HE; Sladek, CD; Somponpun, SJ, 2004) |
| " The functional implications of this pathway in cardiovascular functions were verified using Fos protein induction in response to hypotension induced by continuous intravenous administration of hydralazine-hydrochloride." | 3.72 | Parabrachial inputs to Fos-immunoreactive neurons in the lateral central nucleus of amygdala activated by hypotension: a light and electron microscopic study in the rat. ( Gu, H; Li, HP; Matsumoto, Y; Miki, T; Satriotomo, I; Takeuchi, Y; Xie, Q, 2004) |
| "Previous experiments have indicated that arterial hypotension increases plasma oxytocin (OT) levels in rats and that OT infused intravenously causes an increase in plasma renin activity (PRA)." | 3.71 | Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats. ( Huang, W; Sjöquist, M; Skott, O; Stricker, EM; Sved, AF, 2001) |
| " The RVLM of six unanesthetized rats subjected to 2 hours of hydralazine-induced hypotension contained tenfold more c-Fos-ir DNPI/VGLUT2 neurons than that of six saline-treated controls." | 3.71 | Vesicular glutamate transporter DNPI/VGLUT2 is expressed by both C1 adrenergic and nonaminergic presympathetic vasomotor neurons of the rat medulla. ( Guyenet, PG; Rosin, DL; Schreihofer, AM; Sevigny, CP; Stornetta, RL, 2002) |
| " Plasma epinephrine and norepinephrine levels in response to hydralazine-induced hypotension were measured in these animals." | 3.69 | Modulatory effects of endogenous adenosine on epinephrine secretion from the adrenal medulla of the rat. ( Ho, WY; Kuan, CJ; Lin, HC; Tseng, CJ; Tung, CS, 1994) |
| "Hydralazine (H) induces hypotension accompanied by cardiac stimulation due to activation of the arterial baroreflex." | 3.69 | Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats. ( Vidrio, H, 1996) |
| "We evaluated the effect of different vasodilators on ventricular end-systolic stress by investigating the impact of sodium nitroprusside, nifedipine, and hydralazine on blood pressure, aortic stiffness, and wave reflection during drug-induced hypotension (to 80 mm Hg mean blood pressure) in normotensive (central aortic mean blood pressure, 116 to 119 mm Hg; systolic pressure, 133 to 137 mm Hg), nonanesthetized, unrestrained rats." | 3.69 | Vasodilators, aortic elasticity, and ventricular end-systolic stress in nonanesthetized unrestrained rats. ( Atkinson, J; Duvivier, C; Lartaud-Idjouadiene, I; Marque, V; Niederhoffer, N; Peslin, R, 1997) |
| "Sixteen patients (13-38 yr) undergoing spinal fusion for scoliosis under controlled hypotension were studied to determine the haemodynamic and neuroendocrine responses to IV dihydralazine (1." | 3.67 | Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. ( Bourreli, B; Drouet, JC; Gunst, JP; Passuti, N; Pinaud, M; Remi, JP, 1988) |
| "The oral angiotensin-converting enzyme inhibitor captopril (CPT) produces beneficial hemodynamic and clinical responses in patients with chronic congestive heart failure (CHF)." | 3.66 | Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost. ( Chatterjee, K; Parmley, WW; Rouleau, JL, 1982) |
| "The hemodynamic benefits and safety of combined therapy with captopril and hydralazine were studied during invasive hemodynamic monitoring in 14 patients with severe heart failure." | 3.66 | Hemodynamic responses to combined therapy with captopril and hydralazine in patients with severe heart failure. ( Combs, DT; Hanlon, JT; Massie, BM; Packer, M, 1983) |
| " Other reported effects are toxic confusional states and psychotic reactions." | 2.36 | Psychiatric side effects of antihypertensive drugs other than reserpine. ( Fleminger, R; Paykel, ES; Watson, JP, 1982) |
| "A 31-year-old woman developed bilateral posterior ischemic optic neuropathy and infarctions of the cerebral arterial border zones and spinal cord after correction of malignant hypertension." | 1.35 | Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension. ( An, SJ; Choi, JH; Choi, KD; Kim, HJ; Kim, JS; Lee, JE, 2008) |
| "Hydroxylamine hypotension was enhanced by the SSAO inhibitor isoniazid and the SSAO substrate methylamine, a pattern shared by hydralazine." | 1.34 | Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor. ( Medina, M; Vidrio, H, 2007) |
| "The hypotension was caused by decreases in cardiac index and stroke volume because peripheral resistance did not change." | 1.30 | Role of cardiac output in ethanol-evoked attenuation of centrally mediated hypotension in conscious rats. ( Abdel-Rahman, AA; El-Mas, MM, 1997) |
| "Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats." | 1.25 | Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (55.13) | 18.7374 |
| 1990's | 9 (11.54) | 18.2507 |
| 2000's | 17 (21.79) | 29.6817 |
| 2010's | 8 (10.26) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Kausar, M | 1 |
| Husain, S | 1 |
| Hussain, R | 1 |
| Sharma, C | 1 |
| Soni, A | 1 |
| Gupta, A | 1 |
| Verma, A | 1 |
| Verma, S | 1 |
| Sridharan, K | 1 |
| Sequeira, RP | 1 |
| Nedoboy, PE | 1 |
| Mohammed, S | 1 |
| Kapoor, K | 1 |
| Bhandare, AM | 1 |
| Farnham, MM | 1 |
| Pilowsky, PM | 1 |
| Sharma, KJ | 1 |
| Rodriguez, M | 1 |
| Kilpatrick, SJ | 1 |
| Greene, N | 1 |
| Aghajanian, P | 1 |
| Parker, LM | 1 |
| Le, S | 1 |
| Wearne, TA | 1 |
| Hardwick, K | 1 |
| Kumar, NN | 1 |
| Robinson, KJ | 1 |
| McMullan, S | 1 |
| Goodchild, AK | 2 |
| Haley, GE | 2 |
| Flynn, FW | 3 |
| Choi, JH | 1 |
| Choi, KD | 1 |
| Kim, JS | 1 |
| Kim, HJ | 1 |
| Lee, JE | 1 |
| An, SJ | 1 |
| El-Mas, MM | 2 |
| Abdel-Rahman, AA | 3 |
| Sladek, CD | 2 |
| Stevens, W | 1 |
| Levinson, SR | 1 |
| Song, Z | 1 |
| Jensen, DD | 1 |
| Damanhuri, HA | 1 |
| Burke, PG | 1 |
| Ong, LK | 1 |
| Bobrovskaya, L | 1 |
| Dickson, PW | 1 |
| Dunkley, PR | 1 |
| Pelaez, NM | 1 |
| Schreihofer, AM | 2 |
| Guyenet, PG | 2 |
| Vidrio, H | 3 |
| Medina, M | 2 |
| González-Romo, P | 1 |
| Lorenzana-Jiménez, M | 1 |
| Díaz-Arista, P | 1 |
| Baeza, A | 1 |
| SHAPIRO, AP | 1 |
| GROLLMAN, A | 1 |
| BEIN, HJ | 2 |
| GROSS, F | 2 |
| TRIPOD, J | 3 |
| MEIER, R | 3 |
| SCHUMANN, H | 1 |
| GIAROLA, A | 1 |
| TUCHMANN-DUPLESSIS, H | 1 |
| VANDERKOLK, K | 1 |
| DONTAS, AS | 1 |
| HOOBLER, SW | 1 |
| SILVA MALTEZ, J | 1 |
| BRUNI, C | 1 |
| DRUEY, J | 1 |
| MARXER, A | 1 |
| ABE, T | 1 |
| SUGITA, M | 1 |
| OBATA, K | 1 |
| OGASAWARA, S | 1 |
| YOKOI, T | 1 |
| GARDNER, DL | 1 |
| TANGRI, KK | 1 |
| BHARGAVA, KP | 1 |
| BRICAUD, H | 1 |
| DALLOCCHIO, M | 1 |
| SAUTRON, J | 1 |
| BROUSTET, P | 1 |
| FRIGERIO, G | 1 |
| HUEGIN, W | 1 |
| BOETTIGER, LE | 1 |
| MALMBORG, RO | 1 |
| MICHAELI, EW | 1 |
| BELLUSCHI, A | 1 |
| VACCHINI, V | 1 |
| MORRIS, JA | 1 |
| SMITH, RW | 1 |
| ASSALI, NS | 1 |
| SKINNER, DG | 1 |
| HAYES, MA | 1 |
| SCHMITT, H | 1 |
| GICQUEL, J | 1 |
| CRAVER, BN | 1 |
| BARRETT, W | 1 |
| CAMERON, A | 1 |
| YONKMAN, FF | 1 |
| Takeuchi, Y | 1 |
| Xie, Q | 1 |
| Miki, T | 1 |
| Matsumoto, Y | 1 |
| Satriotomo, I | 1 |
| Li, HP | 1 |
| Gu, H | 1 |
| Howe, HE | 1 |
| Somponpun, SJ | 1 |
| Wang, X | 1 |
| Li, G | 1 |
| Kihara, M | 1 |
| Sato, K | 1 |
| Hashimoto, T | 1 |
| Imai, N | 1 |
| Toya, Y | 1 |
| Umemura, S | 1 |
| Anand, IS | 1 |
| Tam, SW | 2 |
| Rector, TS | 1 |
| Taylor, AL | 2 |
| Sabolinski, ML | 2 |
| Archambault, WT | 1 |
| Adams, KF | 1 |
| Olukotun, AY | 2 |
| Worcel, M | 2 |
| Cohn, JN | 3 |
| Ahlgren, J | 1 |
| Porter, K | 1 |
| Hayward, LF | 1 |
| Ziesche, S | 1 |
| Yancy, CW | 1 |
| Carson, P | 1 |
| Ferdinand, K | 1 |
| Taylor, M | 1 |
| Adams, K | 1 |
| Ofili, E | 1 |
| Lin, HC | 2 |
| Wan, FJ | 1 |
| Paykel, ES | 1 |
| Fleminger, R | 1 |
| Watson, JP | 1 |
| Chatterjee, K | 1 |
| Rouleau, JL | 1 |
| Parmley, WW | 1 |
| Rubin, LJ | 1 |
| Massie, BM | 1 |
| Packer, M | 1 |
| Hanlon, JT | 1 |
| Combs, DT | 1 |
| Baum, T | 1 |
| Sabin, C | 1 |
| Moran, RM | 1 |
| Kaplan, RP | 1 |
| Tseng, CJ | 1 |
| Ho, WY | 1 |
| Tung, CS | 1 |
| Kuan, CJ | 1 |
| Radulovacki, M | 1 |
| Trbovic, S | 1 |
| Carley, DW | 1 |
| Schiltz, JC | 1 |
| Hoffman, GE | 1 |
| Stricker, EM | 3 |
| Sved, AF | 3 |
| Niederhoffer, N | 1 |
| Marque, V | 1 |
| Lartaud-Idjouadiene, I | 1 |
| Duvivier, C | 1 |
| Peslin, R | 1 |
| Atkinson, J | 1 |
| Curtis, KS | 1 |
| Cunningham, JT | 1 |
| Heesch, CM | 1 |
| Stocker, SD | 1 |
| Huang, W | 1 |
| Sjöquist, M | 1 |
| Skott, O | 1 |
| Stornetta, RL | 1 |
| Sevigny, CP | 1 |
| Rosin, DL | 1 |
| Gant, NF | 1 |
| Madden, JD | 1 |
| Siiteri, PK | 1 |
| MacDonald, PC | 1 |
| Pettinger, WA | 1 |
| Keeton, K | 1 |
| Imhof, P | 1 |
| Haeusler, G | 1 |
| Gerold, M | 1 |
| Henrich, WL | 1 |
| Cronin, R | 1 |
| Miller, PD | 1 |
| Anderson, RJ | 1 |
| Mizroch, S | 1 |
| Yurasek, M | 1 |
| Zhang, C | 1 |
| Hsueh, W | 1 |
| Derham, RJ | 1 |
| Robinson, J | 1 |
| Hammond, TG | 1 |
| Mosesson, MW | 1 |
| Hubbard, JW | 1 |
| Buchholz, RA | 1 |
| Reed, K | 1 |
| Nathan, MA | 1 |
| Keeton, TK | 1 |
| Bourreli, B | 1 |
| Pinaud, M | 1 |
| Passuti, N | 1 |
| Gunst, JP | 1 |
| Drouet, JC | 1 |
| Remi, JP | 1 |
| Cummings, JR | 1 |
| Welter, AN | 1 |
| Grace, JL | 1 |
| Gray, WD | 1 |
| Tristani, FE | 1 |
| Dahr, AS | 1 |
| George, CF | 1 |
| Dollery, CT | 1 |
| Carstens, E | 1 |
| Balazs, T | 1 |
| Payne, BJ | 1 |
| Higgins, JT | 1 |
6 reviews available for hydralazine and Blood Pressure, Low
| Article | Year |
|---|---|
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
Psychiatric side effects of antihypertensive drugs other than reserpine.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin; | 1982 |
Cardiovascular effects of vasodilator therapy for pulmonary arterial hypertension.
Topics: Cardiac Output; Echocardiography; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Hypote | 1983 |
[Treatment of cardiac failure with vasodilators (author's transl)].
Topics: Cardiac Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; Hydralazine; Hypotension; I | 1978 |
Severe preeclampsia: is vasodilation therapy with hydralazine dangerous for the preterm fetus?
Topics: Female; Fetus; Humans; Hydralazine; Hypotension; Pre-Eclampsia; Pregnancy | 1990 |
3 trials available for hydralazine and Blood Pressure, Low
| Article | Year |
|---|---|
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd | 2017 |
Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial.
Topics: Adult; Aged; Arthralgia; Biomarkers; Black or African American; Cardiovascular Agents; Cause of Deat | 2007 |
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; | 1983 |
69 other studies available for hydralazine and Blood Pressure, Low
| Article | Year |
|---|---|
Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypotension; Lab | 2023 |
pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension.
Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hybrido | 2016 |
Risks of parenteral antihypertensive therapy for the treatment of severe maternal hypertension are low.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension, Pregnancy | 2016 |
Neurochemistry of neurons in the ventrolateral medulla activated by hypotension: Are the same neurons activated by glucoprivation?
Topics: Animals; Antihypertensive Agents; Catecholamines; Deoxyglucose; Enkephalins; Gene Expression Regulat | 2017 |
Blockade of NK3R signaling in the PVN decreases vasopressin and oxytocin release and c-Fos expression in the magnocellular neurons in response to hypotension.
Topics: Animals; Blood Pressure; Cell Nucleus; Hydralazine; Hypotension; Hypothalamus, Anterior; Immunohisto | 2008 |
Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Brain Stem Infarctions; C | 2008 |
Bradykinin B2 receptor-dependent enhancement of enalapril-evoked hypotension in ethanol-fed female rats.
Topics: Animals; Baroreflex; Bradykinin; Clonidine; Enalapril; Ethanol; Female; Hemodynamics; Hydralazine; H | 2011 |
Characterization of nuclear neurokinin 3 receptor expression in rat brain.
Topics: Animals; Brain; Cell Line, Transformed; Cell Nucleus; CHO Cells; Cricetinae; Cricetulus; Epitopes; G | 2011 |
Tyrosine hydroxylase phosphorylation in catecholaminergic brain regions: a marker of activation following acute hypotension and glucoprivation.
Topics: Animals; Brain; Catecholamines; Hydralazine; Hypotension; Male; Phosphorylation; Rats; Rats, Sprague | 2012 |
Decompensated hemorrhage activates serotonergic neurons in the subependymal parapyramidal region of the rat medulla.
Topics: Animals; Blood Pressure; Enkephalins; gamma-Aminobutyric Acid; Heart Rate; Hydralazine; Hypotension; | 2002 |
Semicarbazide-sensitive amine oxidase substrates potentiate hydralazine hypotension: possible role of hydrogen peroxide.
Topics: Amine Oxidase (Copper-Containing); Anesthesia; Animals; Aorta; Hydralazine; Hydrogen Peroxide; Hypot | 2003 |
A critical evaluation of the hypotensive asction of hydrallazine, hexamethonium, tetraethylammonium and dibenzyline salts in human and experimental hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypotension; Muscle Relaxants, Cent | 1953 |
[Experimental studies on the effects of the hypotension provoking hydrazinophthalazine derivatives apresoline and nepresol on blood circulation].
Topics: Antihypertensive Agents; Blood Circulation; Humans; Hydralazine; Hypotension; Mental Disorders; Symp | 1953 |
[Effect of hypotensive nepresol on heart volume and vascular resistance in hypertensive patients].
Topics: Blood Circulation; Cardiac Volume; Heart; Hydralazine; Hypertension; Hypotension; Sympatholytics; Va | 1953 |
[Clinico-experimental research on circulatory action of some hydrazinophthalazine derivatives with hypotensive action].
Topics: Antihypertensive Agents; Female; Hydralazine; Hypertension; Hypotension; Pregnancy; Pregnancy Compli | 1953 |
[Hypotensive and cardiovascular effect of two hydrazinophthalazines in animals].
Topics: Animals; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Humans; Hydralazine; H | 1954 |
Renal and hypotensive effects of acute and chronic oral treatment with 1-hydrazinophthalazine (apresoline) in hypertension.
Topics: Administration, Oral; Humans; Hydralazine; Hypertension; Hypotension; Kidney; Sympatholytics | 1954 |
[Clinical trial of a new hypotensive drug, 1-hydrazinophthalazine (apresoline)].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Hypotension; Sympatholytics | 1954 |
[The change of hypotensive effect of apresoline and nepresol by the reaction with serum components].
Topics: Blood Pressure; Blood Pressure Determination; Blood Proteins; Hydralazine; Hypotension; Serum; Sympa | 1954 |
Hypotensive hydrazinophthalazines and related compounds.
Topics: Hydralazine; Hypotension; Sympatholytics | 1959 |
[Hypotensive effect of combined treatment with esidres and serpasil-apresoline].
Topics: Chlorothiazide; Combined Modality Therapy; Hydralazine; Hydrazines; Hypotension; Manipulation, Osteo | 1961 |
The relationship between intermittent hypotension and the prevention by hydralazine of acute vascular disease in rats with steroid hypertension.
Topics: Animals; Hydralazine; Hypertension; Hypotension; Peripheral Vascular Diseases; Rats; Vascular Diseas | 1960 |
The central hypotensive action of 1-hydrazinophthalazine (C-5968).
Topics: Humans; Hydralazine; Hypotension | 1960 |
[A new hypotensive drug: guanethidine. Its association with the hydralazines].
Topics: Amidines; Antihypertensive Agents; Guanethidine; Hydralazine; Hypertension; Hypotension | 1961 |
[Controlled clinical research on a new hypotensive combination (mebutamate-hydralazine-reserpine)].
Topics: Antihypertensive Agents; Antipsychotic Agents; Carbamates; Hydralazine; Hypotension; Reserpine | 1963 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine | 1964 |
[CLINICAL EVALUATION OF A PHARMACOLOGIC ASSOCIATION WITH HYPOTENSIVE ACTION].
Topics: Antihypertensive Agents; Biomedical Research; Carbamates; Drug Therapy; Electric Impedance; Humans; | 1964 |
HEMODYNAMIC ACTION OF VASOPRESSOR AND VASODEPRESSOR AGENTS IN ENDOTOXIN SHOCK.
Topics: Angiotensins; Blood Circulation; Blood Pressure; Blood Pressure Determination; Cardiac Output; Dogs; | 1965 |
EFFECT OF STAPHYLOCOCCAL TOXIN ON RENAL FUNCTION: IRREVERSIBLE SHOCK.
Topics: Angiotensins; Antitoxins; Dogs; Hydralazine; Hypotension; Kidney Diseases; Kidney Function Tests; Pa | 1965 |
[Central origin of the hypotensive action of hydralazine].
Topics: Humans; Hydralazine; Hypotension; Sympatholytics | 1955 |
The activities of 1-hydrazinophthalazine (Ba-5968); a hypotensive agent.
Topics: Antihypertensive Agents; Hydralazine; Hypotension; Sympatholytics | 1951 |
Parabrachial inputs to Fos-immunoreactive neurons in the lateral central nucleus of amygdala activated by hypotension: a light and electron microscopic study in the rat.
Topics: Amygdala; Animals; Biotin; Dextrans; Horseradish Peroxidase; Hydralazine; Hypotension; Immunohistoch | 2004 |
Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons.
Topics: Acetates; Animals; Catecholamines; Cell Compartmentation; Cell Nucleus; Cytoplasm; Endosomes; Hydral | 2004 |
Site-dependent inhibition of neuronal c-jun in the brainstem elicited by imidazoline I1 receptor activation: role in rilmenidine-evoked hypotension.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 2005 |
Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Blotting, Western; Hydralazine; Hypotension; | 2006 |
Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial.
Topics: Adult; Aged; Antihypertensive Agents; Black or African American; Blood Pressure; Comorbidity; Drug C | 2007 |
Hemodynamic responses and c-Fos changes associated with hypotensive hemorrhage: standardizing a protocol for severe hemorrhage in conscious rats.
Topics: Animals; Blood Pressure; Blood Volume; Brain; Consciousness; Heart Rate; Hemorrhage; Hydralazine; Hy | 2007 |
Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor.
Topics: Amine Oxidase (Copper-Containing); Animals; Blood Pressure; Dose-Response Relationship, Drug; Enzyme | 2007 |
Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge.
Topics: Animals; Hydralazine; Hypotension; Hypothalamus; Infusions, Intravenous; Injections, Intraventricula | 2007 |
Hyperbaric oxygenation reduces overexpression of c-Fos and oxidative stress in the brain stem of experimental endotoxemic rats.
Topics: Analysis of Variance; Animals; Brain Stem; Guanidines; Hydralazine; Hyperbaric Oxygenation; Hypotens | 2008 |
Captopril in congestive heart failure: improved left ventricular function with decreased metabolic cost.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Heart Ventricles; Hemodynamics; | 1982 |
Hemodynamic responses to combined therapy with captopril and hydralazine in patients with severe heart failure.
Topics: Aged; Blood Pressure; Captopril; Cardiac Output; Drug Therapy, Combination; Female; Heart Failure; H | 1983 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd | 1981 |
When pruritus leads to hypotension.
Topics: Humans; Hydralazine; Hypotension; Medication Errors; Pruritus | 1980 |
Modulatory effects of endogenous adenosine on epinephrine secretion from the adrenal medulla of the rat.
Topics: Adenosine; Adrenal Medulla; Animals; Captopril; Epinephrine; Hydralazine; Hypotension; Male; Norepin | 1994 |
Patterns of heart rate responses to hydralazine in normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Bradycardia; Female; Heart Rate; Hydralazine; Hyperten | 1996 |
Hypotension reduces sleep apneas in Zucker lean and Zucker obese rats.
Topics: Animals; Electromyography; Hydralazine; Hypotension; Injections, Intraperitoneal; Male; Rats; Sleep | 1996 |
Role of cardiac output in ethanol-evoked attenuation of centrally mediated hypotension in conscious rats.
Topics: Animals; Antihypertensive Agents; Brain; Cardiac Output; Clonidine; Ethanol; Hemodynamics; Hydralazi | 1997 |
Decreases in arterial pressure activate oxytocin neurons in conscious rats.
Topics: Animals; Antihypertensive Agents; Avoidance Learning; Blood Pressure; Chlorisondamine; Conditioning, | 1997 |
Vasodilators, aortic elasticity, and ventricular end-systolic stress in nonanesthetized unrestrained rats.
Topics: Animals; Aorta; Blood Pressure; Elasticity; Hydralazine; Hypotension; Male; Nifedipine; Nitroprussid | 1997 |
Fos expression in brain stem nuclei of pregnant rats after hydralazine-induced hypotension.
Topics: Animals; Antihypertensive Agents; Brain Stem; Cerebral Ventricles; Female; Hydralazine; Hypotension; | 1999 |
Role of renin-angiotensin system in hypotension-evoked thirst: studies with hydralazine.
Topics: Animals; Diazoxide; Drinking; Drug Combinations; Hydralazine; Hypotension; Isoproterenol; Male; Poly | 2000 |
Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats.
Topics: Animals; Diazoxide; Heart Rate; Hormone Antagonists; Hydralazine; Hypotension; Kinetics; Male; Oxyto | 2001 |
Vesicular glutamate transporter DNPI/VGLUT2 is expressed by both C1 adrenergic and nonaminergic presympathetic vasomotor neurons of the rat medulla.
Topics: Amines; Animals; Carrier Proteins; Electrophysiology; Growth Inhibitors; Hydralazine; Hypotension; M | 2002 |
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazi | 1976 |
Altered renin release and propranolol potentiation of vasodilatory drug hypotension.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dose-Response | 1975 |
Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil.
Topics: Angiotensin II; Animals; Blood Pressure; Dihydralazine; Dogs; Female; Guinea Pigs; Hydralazine; Hypo | 1979 |
Hypotensive sequelae of diazoxide and hydralazine therapy.
Topics: Adult; Diazoxide; Drug Synergism; Female; Humans; Hydralazine; Hypotension; Male; Middle Aged; Pregn | 1977 |
Hypotension and bradycardia following diazoxide and hydralazine therapy.
Topics: Bradycardia; Diazoxide; Humans; Hydralazine; Hypertension; Hypotension; Male; Middle Aged | 1977 |
PAF-induced bowel necrosis. Effects of vasodilators.
Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Me | 1991 |
Fatal small-bowel necrosis and pulmonary hypertension in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Humans; Hydralazine; Hypertension, Pulmonary; Hypotension; Infarction; I | 1989 |
Changes in plasma catecholamines and plasma renin activity during hypotension in conscious rats with lesions of the nucleus tractus solitarii.
Topics: Animals; Atenolol; Blood Pressure; Cardiovascular System; Consciousness; Denervation; Electric Stimu | 1988 |
Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion.
Topics: Adolescent; Adult; Anesthesia; Anesthetics; Dihydralazine; Drug Synergism; Enflurane; Female; Humans | 1988 |
Angiotensin blocking actions of guancydine.
Topics: Angiotensin II; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Epinephrin | 1969 |
Studies in clinical shock and hypotension. VII. Renal hemodynamics before and during treatment.
Topics: Acetylcholine; Adult; Aged; Angiotensin II; Blood Flow Velocity; Blood Urea Nitrogen; Cardiac Output | 1970 |
The effect of selective cardiac adrenergic beta-blockade on the hypotensive effect of hydrallazine.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dogs; Drug Antagonism; Electrocardiography; He | 1971 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Myocardial papillary muscle necrosis induced by hypotensive agents in dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carboxylic Acids; Dogs; Electrocardiography; Femal | 1971 |
Escape from sodium-retaining effects of deoxycorticosterone in hypotensive and hypertensive dogs.
Topics: Aminohippuric Acids; Animals; Blood Pressure; Creatinine; Desoxycorticosterone; Dogs; Ephedrine; Fem | 1970 |