hydralazine has been researched along with Blood Pressure, High in 1491 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objectives were to compare the efficacy and safety of intravenous hydralazine and labetalol for acutely lowering severe hypertension in pregnancy." | 9.51 | Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial. ( Bako, B; Dawha, YM; Muhammad, S; Usman, H; Yahya, A; Yekeen, A, 2022) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 9.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| "We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol." | 9.15 | Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 9.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "Although hydralazine has been the drug of choice for treating pregnancy-induced hypertension for some time owing to its effect on peripheral vascular tonus, its effects on utero- and feto-placental circulation are less well understood." | 9.08 | Effects of hydralazine on placental and renal circulation in pre-eclampsia. ( Gennser, G; Gudmundsson, S; Marsal, K, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 9.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| "In order to compare the long-term effects on ambulatory blood pressure and left ventricular hypertrophy of hydralazine and lisinopril we studied 30 patients, all males, still hypertensive (diastolic blood pressure > or = 95 mm Hg) despite combined beta-blocker/diuretic therapy and with echocardiographic evidence of left ventricular hypertrophy (left ventricular mass index > or = 1." | 9.08 | Effects of lisinopril vs hydralazine on left ventricular hypertrophy and ambulatory blood pressure monitoring in essential hypertension. ( Corradi, L; Fogari, R; Lusardi, P; Mugellini, A; Tettamanti, F; Zoppi, A, 1995) |
| "In patients with hypertension persisting on combined diuretic and beta-blocker therapy, the effects of an additional 9-week therapy with a calcium antagonist (nifedipine) versus a classical arterial vasodilator (hydralazine) were compared for changes in blood pressure (BP), plasma catecholamines (n = 15), and left ventricular (LV) systolic and diastolic function (n = 6)." | 9.06 | Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy. ( Burns, RJ; Frankel, D; Leenen, FH; Myers, MG, 1990) |
| "We report the results of a randomized, double-blind, parallel group multicentre study in 120 patients with moderate to severe hypertension, comparing two different types of antihypertensive treatment: a) the standard 'triple therapy' with hydrochlorothiazide, propranolol and hydralazine, and b) the combination of an ACE inhibitor, enalapril with hydrochlorothiazide (HCTZ) and methyldopa." | 9.06 | Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study. ( Ambrosioni, E; Cinotti, G; Cuspidi, C; Leonetti, G; Malini, PL; Morabito, S; Pessina, A; Rappelli, A; Sampieri, L; Semplicini, A, 1990) |
| "The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension." | 9.06 | Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989) |
| "Endralazine and hydralazine were compared in a randomized double-blind, parallel group study lasting 1 year in 30 patients with essential hypertension inadequately controlled by a beta-blocker and a diuretic." | 9.06 | Comparative study of endralazine and hydralazine for the treatment of hypertension uncontrolled by a beta-blocker and diuretic. ( Chazan, BI; Duff, DA; McCallum, A; Whaley, K, 1986) |
| "To investigate the use of felodipine in severe hypertension 2 separate studies were carried out." | 9.06 | The use of felodipine in the treatment of severe hypertension. ( Muir, AL; Wathen, CG, 1987) |
| "Labetalol (Trandate; Allen & Hanburys), a combined alpha- and beta-adrenergic blocking agent, was compared with the more commonly used peripheral vasodilator, dihydrallazine (Nepresol; Ciba), each administered as an infusion, in the treatment of severe hypertension in 20 primigravidas at greater than or equal to 32 weeks' gestation." | 9.06 | Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy. ( Ashe, RG; Moodley, J; Philpott, RH; Richards, AM, 1987) |
| "The effects of graded doses of verapamil were compared with those of a combination of atenolol and hydralazine in a double-blind, randomised, crossover trial in 16 patients with essential hypertension." | 9.06 | Verapamil in essential hypertension: a comparison with atenolol plus hydralazine. ( Bailey, BP; Duggin, GG; Fletcher, PJ; Hall, B; Horvath, JS; Tiller, D, 1987) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 9.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| "This study of guanfacine in 27 patients suffering from moderate-to-severe hypertension showed a satisfactory blood pressure control in 26 patients." | 9.05 | Guanfacine alone and in combination therapy in the treatment of moderate and severe hypertension. ( Seedat, YK, 1983) |
| "The efficacy of a propranolol-hydralazine combination tablet was compared with that of each of its two components in the twice-daily treatment of mild to moderate essential hypertension (diastolic blood pressure: 100 to 125 mmHg)." | 9.05 | Propranolol-hydralazine combination in essential hypertension. ( Binstok, G; del Greco, F; Huang, C; Morledge, JH; Mullane, JF; Pittman, AW; Stevens, JD; Woods, JW, 1983) |
| "We report the results of an observer blind crossover trial in 31 patients with essential hypertension comparing the hypotensive effect of four doses of prazosin and of hydralazine used as the third step of triple therapy and additional data on the efficacy of low dose combinations of these two drugs." | 9.05 | Hydralazine and prazosin in the treatment of hypertension. ( Barnes, JN; Drew, PJ; Sharman, VL; Vandenburg, MJ; Wright, P, 1983) |
| "Despite the short plasma half-life of hydralazine, once daily Slow Apresoline has been shown to maintain blood pressure control in well controlled hypertension." | 9.05 | Evaluation of once daily hydralazine in inadequately controlled hypertension. ( Danielson, M; Kjellberg, J; Ohman, P; Wernersson, B, 1983) |
| "We compared the efficacy and safety of nitrendipine with that of hydralazine in 21 subjects with essential hypertension." | 9.05 | Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension. ( Aguila, E; Baz, R; Lopez, LM; Mehta, JL, 1984) |
| " A survey of 122 patients with resistant hypertension treated long-term with nifedipine and a control group of 102 similar patients treated with hydralazine revealed that nifedipine at an average dose of 40 mg daily caused a fall in blood pressure similar to that achieved with hydralazine in a dose of 86 mg daily." | 9.05 | Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients. ( Bulpitt, CJ; Dollery, CT; Murphy, MB, 1984) |
| "Patients with acute pregnancy-related hypertension were randomized to treatment with 200 mg oral labetalol or 10 mg intramuscular hydralazine." | 9.05 | Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared. ( Calder, AA; Greer, I; Walker, JJ, 1983) |
| "Prazosin was compared with hydralazine in 39 patients (mean age 49 years), who were already on beta-blockade for arterial hypertension." | 9.05 | Peripheral vasodilatation in the treatment of hypertension. Prazosin compared with hydralazine in patients not responding to beta-receptor blockade. ( Fagerberg, SE; Frithz, G; Malmberg, L, 1982) |
| "The effects of hydralazine formulation and dose interval were assessed in 20 patients with hypertension well controlled on conventional hydralazine tablets, 100 mg twice daily, in addition to atenolol and a diuretic." | 9.05 | Hydralazine once daily in hypertension. ( Freestone, S; Ramsay, LE; Silas, JH, 1982) |
| "1 Labetalol, an alpha- and beta- adrenoceptor blocking drug, was compared with acebutolol, alone or associated with dihydralazine in forty patients with moderate essential hypertension." | 9.05 | Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension. ( Corvol, P; Lardoux, MD; Thibonnier, M, 1980) |
| "The effect of a vasodilator (hydralazine), a beta-blocker (oxprenolol) and also their combination, on essential arterial hypertension and plasma renin activity (PRA), was studied." | 9.05 | Hydralazine and oxprenolol in the treatment of hypertension and the effect of these drugs on plasma renin activity. ( Siitonen, L, 1980) |
| "Thirty-one patients with moderate and severe essential hypertension completed a comparative study of oxdralazine and dihydralazine." | 9.05 | Comparative study of oxdralazine and dihydralazine in essential hypertension. ( Criscuolo, D; Piazza, W; Salvadeo, A; Segagni, S; Villa, G, 1981) |
| "Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet." | 9.05 | Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension. ( Broughton Pipkin, F; Lamming, GD; Symonds, EM, 1980) |
| "In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy." | 9.05 | A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985) |
| " Control of hypertension was equivalent in both treatment groups, and in 64 (35%) cases hydralazine had to be added to the treatment to achieve the therapeutic goal (diastolic blood pressure below 85 mm Hg)." | 9.05 | Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa. ( Gallery, ED; Gyory, AZ; Ross, MR, 1985) |
| "The antihypertensive mechanisms of single and combined therapy with a beta-adrenergic antagonist (propranolol) and a vasodilator (hydralazine) were investigated in 9 patients with moderately severe hypertension, who were receiving maintenance diuretic (hydrochlorothiazide) treatment." | 9.05 | Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: hemodynamic and neuroendocrine mechanisms of action. ( Blomqvist, CG; Gaffney, FA; Graham, RM; Mulvihill-Wilson, J; Neal, WW; Pettinger, WA, 1985) |
| "In a series of 450 patients with mild essential hypertension, propranolol alone (P), propranolol plus hydrochlorothiazide (P+T), propranolol plus hydralazine (P+H), and propranolol plus hydrochlorothiazide plus hydralazine (P+T+H) were compared to reserpine plus hydrochlorothiazide (R+T)." | 9.04 | Propranolol in the treatment of essential hypertension. ( , 1977) |
| "The effect on hypertension of hydrochlorothiazide 100 mg daily plus timolol 20-60 mg daily versus hydrochlorothiazide plus placebo and of hydrochlorothiazide plus timolol plus hydralazine 40-200 mg daily versus hydrochlorothiazide plus placebo plus hydralazine was evaluated in a double-blind, randomized, crossover study in 38 patients with hypertension." | 9.04 | Effect of timolol plus hydrochlorothiazide plus hydralazine on essential hypertension. ( Alimadadian, H; Aronow, WS; Burwell, D; Greenfield, R; Mann, W; Van Herick, R, 1978) |
| " Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)." | 9.04 | The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978) |
| " The short term effects of hydrallazine, oxprenolol and oxprenolol plus hydrallazine were studied in five patients with essential hypertension." | 9.04 | Sympathetic reflex responses during treatment of essential hypertension with hydrallazine and oxprenolol. ( Davies, IB; Rosenthal, T; Sever, PS, 1979) |
| "In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)." | 9.04 | [Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978) |
| "Thirty patients suffering from essential hypertension were treated successively with placebo, hydralazine alone, and pindolol (Visken) combined with hydralazine." | 9.04 | Combination therapy of essential hypertension with pindolol (Visken) and hydralazine. ( Persson, I, 1975) |
| "Ten patients not maximally controlled on an oxprenolo/cyclopenthiazide regimen for moderately severe hypertension were treated in a double blind crossover trial with either hydrallazine (75-150 mg/day) or phentolamine (60-120 mg/day) or placebo in addition to their other therapy." | 9.04 | Hydrallazine or phentolamine as adjuncts to beta-adrenoceptor blockade/thiazide therapy in hypertension. ( Kennedy, AC; McKillop, JH; Ward, DM; Winchester, JF, 1976) |
| " Twenty patients with severe or moderate hypertension were treated with minoxidil for 284 patient-months." | 9.04 | Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients. ( Dunea, G; Mahurkar, SD; Mamdani, B, 1976) |
| "Thirty patients suffering from essential hypertension were treated successively with placebo, hydralazine alone, and pindolol (Viskén) combined with hydralazine." | 9.04 | Combination therapy of essential hypertension with pindolol (Visken) and hydralazine. ( Persson, I, 1976) |
| " We present a case report of a premenopausal patient with hydralazine-associated amenorrhea." | 8.98 | Hydralazine-associated Amenorrhea in a Premenopausal Patient With Chronic Kidney Disease: A Case Report and Review of Literature. ( Al-Makki, A; Allspaw, A; Shepler, BM; Yeboah, KA, 2018) |
| "To quantify the effect of hydralazine compared to placebo in randomized controlled trials (RCTs) on all cause mortality, cardiovascular mortality, serious adverse events, myocardial infarctions, strokes, withdrawals due to adverse effects and blood pressure in patients with primary hypertension." | 8.87 | Hydralazine for essential hypertension. ( Kandler, MR; Mah, GT; Salzwedel, DM; Stabler, SN; Tejani, AM, 2011) |
| "To quantify the effect of hydralazine compared to placebo in randomized controlled trials (RCTs) on all cause mortality, cardiovascular mortality, serious adverse events, myocardial infarctions, strokes, withdrawals due to adverse effects and blood pressure in patients with primary hypertension." | 8.86 | Hydralazine for essential hypertension. ( Kandler, MR; Mah, GT; Stabler, SN; Tejani, AM, 2010) |
| "To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy." | 8.82 | Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 8.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| "A 59-year-old man was diagnosed as having constrictive pericarditis 17 months after a typical hydralazine-induced autoimmune syndrome." | 8.79 | Hydralazine-induced constrictive pericarditis. ( el Gamal, MI; Franssen, CF; Gans, RO; Hoorntje, SJ, 1996) |
| "A 52-year-old Hispanic woman with a medical history of resistant hypertension treated with hydralazine 10 mg twice daily for 1 year presented with generalized weakness, dizziness, nausea, vomiting, and gross hematuria." | 8.31 | Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine. ( Agaronov, A; Akhondi, H; Bhatnagar, M; Pepito, D; Sarkisyan, E; Sotoudeh Deilamy, I, 2023) |
| "To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia." | 8.31 | Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023) |
| "Hydralazine, a widely used therapy for hypertension and heart failure, can elicit autoimmune disease, including anti-neutrophil cytoplasmic antibody associated glomerulonephritis (ANCA-GN)." | 8.02 | Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine. ( Appel, GB; Batal, I; Bomback, AS; Canetta, PA; D'Agati, VD; Kudose, S; Markowitz, GS; Radhakrishnan, J; Santoriello, D; Stokes, MB, 2021) |
| "Hydralazine is a common vasodilator which has been used for the treatment of hypertension and heart failure." | 7.96 | Hydralazine-induced antineutrophil cytoplasmic antibody-associated vasculitis with pulmonary-renal syndrome: a case report. ( Al-Abdouh, A; Bekele, A; Garcia, P; Seid, H; Siyal, AM, 2020) |
| "The aim of this study was to evaluate the use of as-needed (PRN) labetalol and hydralazine [intravenous (IV) or oral] in hospitalized medicine patients for the treatment of severe asymptomatic hypertension and to examine the potential negative outcomes associated with their use." | 7.88 | Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients. ( Gaynor, MF; Vondracek, S; Wright, GC, 2018) |
| "To explore the efficacy and safety of intravenous (IV) hydralazine in hospitalized children with hypertension." | 7.83 | Intravenous Hydralazine in Hospitalized Children and Adolescents with Hypertension. ( Bradford, MC; Flynn, JT; Harvey, EM, 2016) |
| "We report a rare case of Hydralazine-induced ANCA associated glomerulonephritis with alveolar hemorrhage in the setting of acute Clostridium Difficile Infection." | 7.83 | Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection. ( Cucu, DF; El Meligy, A; Rasla, S, 2016) |
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 7.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| "Hydralazine, a vasodilator used in resistant hypertension (RH) treatment is metabolized by an acetylation reaction mediated by N-acetyltransferase 2, the activity of which depends on NAT2 polymorphisms." | 7.80 | Different phenotypes of the NAT2 gene influences hydralazine antihypertensive response in patients with resistant hypertension. ( Muxfeldt, ES; Salles, GF; Santos, AR; Spinasse, LB; Suffys, PN, 2014) |
| "Hydralazine is a medication that has been used to manage hypertension and heart failure." | 7.80 | Hydralazine associated pauci-immune glomerulonephritis. ( Baiswar, S; Suneja, M; Vogelgesang, SA, 2014) |
| " In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension." | 7.78 | Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012) |
| "We have previously found that T lymphocytes are essential for development of angiotensin II-induced hypertension; however, the mechanisms responsible for T-cell activation in hypertension remain undefined." | 7.76 | Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. ( Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C, 2010) |
| " Therefore, olmesartan, an angiotensin type 1 receptor blocker, might affect oxidative stress in the brains of stroke-prone spontaneously hypertensive rats (SHRSP)." | 7.75 | Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. ( Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K, 2009) |
| "We report a case of hydralazine-induced alveolar hemorrhage and anti-neutrophil cytoplasmic antibody (ANCA)-positive pauci-immune glomerulonephritis, with serum anti-histone antibodies present, features not previously described in the literature with this drug." | 7.75 | Hydralazine-induced ANCA-positive pauci-immune glomerulonephritis: a case report and literature review. ( Dobre, M; Negrea, L; Wish, J, 2009) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 7.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| "To test the functional consequences of blocking the local renin-angiotensin system (RAS), we investigated the effects of an angiotensin II type 1 receptor blocker (ARB), candesartan, on the systemic gene expression profile of five important organs (brain, heart, kidney, liver and adipose tissues) in the stroke-prone spontaneously hypertensive rat (SHRSP), an established model of essential hypertension and cardiovascular disorders, and its normotensive control, the Wistar Kyoto (WKY) rat." | 7.74 | Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. ( Birukawa, N; Jesmin, S; Kato, N; Liang, YQ; Ochiai, Y; Serizawa, M, 2008) |
| " Azelnidipine, hydralazine, or vehicle was orally administered for 28 days to stroke-prone spontaneously hypertensive rats." | 7.74 | Azelnidipine decreases sympathetic nerve activity via antioxidant effect in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats. ( Araki, S; Hirooka, Y; Kishi, T; Koga, Y; Konno, S; Sunagawa, K, 2008) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 7.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| "The objectives were two-fold: (1) determine whether the use of hydralazine as antihypertensive therapy during obesity development exacerbated obesity-related cardioacceleration and hormonal abnormalities; (2) determine whether the absence of hypertension in obesity attenuated obesity-related abnormalities in hemodynamics, cardiac hypertrophy, and hormonal profile." | 7.72 | Hydralazine as antihypertensive therapy in obesity-related hypertension. ( Carroll, JF; Cohen, JS; King, JW, 2004) |
| "Angiotensin II (Ang II) is a potent vasoconstrictor and induces inflammation and end-organ injury through its activation of the proinflammatory transcription factor, nuclear factor-kappaB (NF-kappaB)." | 7.72 | Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta. ( Chen, Y; Currie, RW; Ross, BM, 2004) |
| " The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 7.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
| " Nifedipine is often used to control hypertension in kidney graft recipients." | 7.69 | Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994) |
| "To audit the use of bolus hydralazine for control of severe hypertension within a protocol for the management of severe pre-eclampsia." | 7.69 | Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia. ( de Swiet, M; Paterson-Brown, S; Redfern, N; Robson, SC; Walkinshaw, SA, 1994) |
| "The present study evaluated the effects of lovastatin on renal function and the development of hypertension in spontaneously hypertensive rats (SHR)." | 7.69 | Lovastatin prevents development of hypertension in spontaneously hypertensive rats. ( Jiang, J; Roman, RJ, 1997) |
| "The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR)." | 7.68 | Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study. ( Amenta, F; Bronzetti, E; Ciriaco, E; Felici, L; Ferrante, F, 1992) |
| " This study was undertaken in gravid ewes to determine the effects of treatment of cocaine-induced hypertension with hydralazine (Apresoline) on the maternal and fetal cardiovascular systems, catecholamine response, blood gas and acid-base status, and uterine blood flow (UBF)." | 7.68 | Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe. ( Espinoza, MI; Hughes, SC; Johnson, JL; Messer, CP; Parer, JT; Rosen, MA; Shnider, SM; Vertommen, JD, 1992) |
| "The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension." | 7.68 | Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991) |
| "7 years, mean +/- SD) received intravenous doses of labetalol, an alpha 1- and beta-adrenergic blocker, on 15 separate occasions for treatment of hypertension." | 7.68 | Intravenously administered labetalol for treatment of hypertension in children. ( Bunchman, TE; Lynch, RE; Wood, EG, 1992) |
| "Acute cocaine intoxication has been associated with elevated blood pressure and placental abruption." | 7.68 | Cocaine intoxication associated with abruptio placentae. ( Clark, JF; Flowers, D; Westney, LS, 1991) |
| "We compared the effects of the angiotensin-converting enzyme inhibitor enalapril and a conventional antihypertensive regimen (hydralazine and metoprolol) on kidney function, albuminuria, and glomerular ultrastructure in hypertensive diabetic and nondiabetic rats." | 7.68 | Nephropathy in model combining genetic hypertension with experimental diabetes. Enalapril versus hydralazine and metoprolol therapy. ( Allen, TJ; Clarke, BE; Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC; Papazoglou, D, 1990) |
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 7.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| "A case of retroperitoneal fibrosis possibly associated with hydralazine, hydrochlorothiazide and ampicillin therapy is reported." | 7.67 | Hydralazine, hydrochlorothiazide and ampicillin associated with retroperitoneal fibrosis: case report. ( Waters, VV, 1989) |
| "2 mg propranolol intravenously resulted in acute pulmonary edema." | 7.67 | Severe hypertension, propranolol, and acute pulmonary edema. ( Desai, SP; Fleming, TC; Pierce, EC, 1987) |
| "The hemodynamic changes after intravenous administration of hydralazine were assessed using M-mode echocardiography in 13 pregnant patients with severe hypertension." | 7.67 | Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension. ( Kuzniar, J; Piela, A; Skret, A; Szmigiel, Z; Zaczek, T, 1985) |
| "Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 7.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
| "When administered to young spontaneously hypertensive rats (SHRs), dihydralazine (25 mg kg-1, daily) and captopril (100 mg kg-1, daily) prevent with the same efficacy genetic hypertension development (GHD)." | 7.66 | Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats. ( Freslon, JL; Giudicelli, JF, 1983) |
| "The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine." | 7.66 | Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Thornström, S, 1983) |
| "The influence of various disease states, other than hypertension, on the pharmacokinetic behaviour of hydralazine is not completely known." | 7.66 | Pharmacokinetics of oral hydralazine in chronic heart failure. ( Hanson, A; Johansson, BW; Wåhlander, LA; Wernersson, B, 1983) |
| "In 23 patients with primary hypertension, the efficacy and tolerability of slow-release hydralazine administered once daily were compared with those of conventional hydralazine given two to four times a day." | 7.66 | Efficacy and tolerability of hydralazine, in conventional and slow-release preparations, during long-term treatment of primary hypertension. ( Berglund, J; Eliasson, K; Lins, LE; Wernersson, B, 1983) |
| "26 patients with severe hypertension (10 essential, 9 renal parenchymatous, 7 renovascular) and a mean age of 42 years were treated with the new oral converting enzyme inhibitor captopril (SQ 14225)." | 7.66 | [Captopril in treatment-resistant hypertension (author's transl)]. ( Lüscher, T; Siegenthaler, W; Studer, A; Vetter, W, 1980) |
| "A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies." | 7.66 | Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980) |
| "Oxdralazine, a pyridazine shown to induce prolonged arteriolar dilation in animals, was given orally in doses of 15 to 30 mg to 7 subjects with hypertension." | 7.66 | Hemodynamic effects of oxdralazine and hydralazine in hypertension. ( Cohn, JN; Moskowitz, RM, 1980) |
| "The effect of long-term treatment of hypertension with propranolol, alone or in combination with hydrochlorothiazide and/or dihydralazine, was investigated in 93 patients with various types of hypertension." | 7.66 | [Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine]. ( Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC, 1978) |
| "Eleven patients with essential hypertension were given hydralazine (25 mg b." | 7.66 | Renal plasma flow and cardiac output during hydralazine and propranolol treatment in essential hypertension. ( Falch, DK; Norman, N; Odegaard, AE, 1978) |
| "In 16 patients with hypertension, BP could not be controlled satisfactorily by treatment with propranolol alone (mean dosage 325 mg/day)." | 7.66 | Changes in plasma volume and extracellular fluid volume and after addition of hydralazine to propranolol treatment in patients with hypertension. ( Ibsen, H; Jensen, HA; Leth, A; Rasmussen, K, 1978) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 7.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13." | 7.65 | Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975) |
| "The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension." | 7.65 | Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975) |
| "A patient with severe progressive hypertension was treated with parenteral hexamethonium and large dosages of hydralazine." | 7.65 | Persistent reversal of severe systemic hypertension after prolonged toxic reaction to hydralazine. ( Abrams, DL; Kaplan, BM; Miller, AJ, 1975) |
| "Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 7.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
| " Full-text, English-language articles describing IV labetalol and/or hydralazine use for non-emergent HTN in an inpatient setting that focused on clinical outcomes (ie vitals, adverse effects, healthcare utilisation) were included." | 6.72 | Safety and efficacy of intravenous hydralazine and labetalol for the treatment of asymptomatic hypertension in hospitalised patients: A systematic review. ( Cawoski, JR; Covvey, JR; DeBiasio, KA; Donnachie, SW; Guarascio, AJ; Montepara, CA; Nemecek, BD; Timanus, EA; Zimmerman, DE, 2021) |
| "Hydralazine was found to be superior in its ability to effect more rapidly a lower mean arterial blood pressure." | 6.66 | Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension. ( Griffis, KR; Martin, JN; Martin, RW; Morrison, JC; Palmer, SM, 1989) |
| "The felodipine treated patients experienced more ankle swelling and flushing than those in the hydralazine group who experienced more headache and minor gastro-intestinal upset." | 6.66 | Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group. ( , 1986) |
| " The duration of action also varied in the labetalol group, with the shortest duration occurring in those patients who required the highest dosage for BP control." | 6.66 | A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy. ( Amon, E; Gonzalez, AR; Mabie, WC; Sibai, BM, 1987) |
| " Apart from the hydrochlorothiazide dosage which was fixed, the dosage of the other active drugs was titrated incrementally until the target blood pressure level was achieved." | 6.65 | An appraisal of antihypertensive efficacy and adverse reactions with two drug regimens: enalapril maleate as part of triple therapy compared to conventional triple therapy in moderate to severe hypertension. ( Fernandez, PG; Galway, AB; Kim, BK, 1984) |
| "The possibility to apply impedance cardiography technique and individual statistical analysis based on Dixon's criterion to pharmacodynamic studies of single hydralazine ( apressine ), prazosine ( pratsiol ), endralazine ( mirethilan ), propranolol (obsidan) doses is discussed." | 6.65 | [Methodologic approach to individual evaluation of the pharmacodynamic effects of single doses of hydralazine, endralazine, prazosine and propranolol in hypertension patients]. ( Izotov, AI; Postol'nikov, SF; Vygodin, VA, 1984) |
| "The optimal daily dose and dose regimen of a new drug combination (Pertenso), consisting of 10 mg bemetizide, 20 mg triamterene, 20 mg dihydralazine and 20 mg bupranolol were tested in 14 hypertensive outpatients (WHO I to III) in a single blind crossover trial." | 6.65 | [Treatment of hypertension with a drug combination, consisting of bemetizide, triamterene, dihydralazine and bupranolol (author's transl)]. ( Brandstetter, G; Gasser, RW; Skrabal, F, 1982) |
| "Blood pressure (BP) control and tolerability of three two-week dosage regimens of hydralazine--conventional hydralazine q." | 6.65 | Hydralazine in arterial hypertension. Randomized double-blind comparison of conventional/Slow-Release formulation and of b.i.d./q.i.d. dosage regimens. ( Holst, B; Krogsgaard, AR; Lenz, K; Wulff, K, 1980) |
| "Evidence of cardiac hypertrophy was slow to resolve despite good control of blood pressure." | 6.64 | Double-blind comparison of minoxidil and hydrallazine in severe hypertension. ( Bennett, CM; Connor, G; Wilburn, RL, 1976) |
| "Labetalol is a useful hypotensive drug with effect similar to that of a combination of a beta-adrenoceptor blocking drug and a vasodilator." | 6.64 | Labetalol compared with prindolol plus hydraliazine in the treatment of hypertension: a double-blind cross-over study. ( Barnett, AJ; Guest, C; Kalowski, S, 1978) |
| " The mean coefficient of variation for the 2 days prior to initiation of hydralazine dosing was 4." | 6.64 | Duration of hydralazine action in hypertension. ( Boles, M; Dayton, PG; Israili, ZH; McNay, JL; O'Malley, K; Segal, JL, 1975) |
| "Magnesium sulfate was promptly administered on admission to every woman to prevent seizure." | 5.56 | Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020) |
| "Hypertension is an important risk factor for nonalcoholic steatohepatitis." | 5.56 | The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension. ( Asano, T; Hashimoto, S; Kitamori, K; Naito, H; Nakajima, T; Yuan, Y, 2020) |
| "The objectives were to compare the efficacy and safety of intravenous hydralazine and labetalol for acutely lowering severe hypertension in pregnancy." | 5.51 | Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial. ( Bako, B; Dawha, YM; Muhammad, S; Usman, H; Yahya, A; Yekeen, A, 2022) |
| "Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats." | 5.43 | Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016) |
| " Demographic data and data on adverse effects (AE), BP, and heart rate (HR) prior to and after each first dose were collected." | 5.40 | The efficacy and safety of intravenous hydralazine for the treatment of hypertension in the hospitalized child. ( Chessman, K; Egan, B; Hailpern, SM; Jones, J; Ostrye, J; Shatat, IF, 2014) |
| " Current recommendations on hydralazine dosage are unsatisfactory for the 40% of hypertensive patients who are rapid acetylators." | 5.27 | Should the acetylator phenotype be determined when prescribing hydralazine for hypertension? ( Freestone, S; Ollerenshaw, JD; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1984) |
| "075 mg/kg) of felodipine in combination with the beta-blocker and diuretic." | 5.27 | Felodipine in combination with a beta-blocker and a diuretic in chronic treatment of patients with refractory primary hypertension. ( Andersson, OK; Granérus, G; Hedner, T, 1987) |
| "Captopril was helpful in the management of refractory hypertension in most cases." | 5.26 | Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension. ( Julius, S; Nicholls, MG; Zweifler, AJ, 1981) |
| "Dihydralazine treatment which lowered blood pressure in young rats from the Lyon Hypertensive Strain (LHS), did not change phenylethanolamine-N-methyltransferase (PNMT) activity, but decreased tyrosine hydroxylase and dopamine-beta-hydroxylase activities in the C2 medullary region." | 5.26 | Dihydralazine and catecholamine-synthesizing enzymes in spontaneous hypertension. ( Denoroy, L; Renaud, B; Sacquet, J; Sassard, J; Vincent, M, 1979) |
| "Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful." | 5.26 | Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978) |
| " The drugs could be given in a twice-daily dosage and had a much higher degree of patient acceptance." | 5.25 | Oxprenolol and hydrallazine in the treatment of hypertension. ( Freeman, JW; Knight, LW, 1975) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 5.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| "Hydralazine is a vasodilator used to treat hypertension, pre-eclampsia, and heart failure." | 5.22 | A review on the clinical pharmacokinetics of hydralazine. ( Alqahtani, F; Ashraf, W; Hussain, I; Imran, I; Khalid, S; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Shahzad Qamar, A; Zamir, A, 2022) |
| "Sixteen older persons free of known cardiovascular disease with the exception of hypertension had noninvasive tonometry and cardiac ultrasound to evaluate central augmentation index (AI) and diastolic function at baseline and after randomized, blinded administration of intravenous B-type natriuretic peptide (BNP) and hydralazine in a crossover design." | 5.17 | Left ventricular responses to acute changes in late systolic pressure augmentation in older adults. ( Eggleston, K; Hetzel, SJ; Mitchell, GF; Skalski, J; Sweitzer, NK; Velez, M, 2013) |
| "We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol." | 5.15 | Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 5.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "Hydralazine, an arterial vasodilator, is a widely used medication for the management of hypertension and heart failure, especially for patients who cannot tolerate the use of ACEIs or ARBs." | 5.12 | Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review. ( Al-Sadawi, M; Battisha, A; Doughem, K; Konduru, L; Madoukh, B; Shaikh, S; Sheikh, O, 2021) |
| "Essential hypertension is a common disorder, associated with increased endothelin-1-mediated vasoconstrictor tone at rest." | 5.10 | Endogenous endothelin-1 limits exercise-induced vasodilation in hypertensive humans. ( Jenkins, DG; McEniery, CM; Webb, DJ; Wilkinson, IB, 2002) |
| "Although hydralazine has been the drug of choice for treating pregnancy-induced hypertension for some time owing to its effect on peripheral vascular tonus, its effects on utero- and feto-placental circulation are less well understood." | 5.08 | Effects of hydralazine on placental and renal circulation in pre-eclampsia. ( Gennser, G; Gudmundsson, S; Marsal, K, 1995) |
| "Fifty-one women with pregnancy-induced hypertension (PIH) were randomly allocated to one of three treatment groups: A: hydralazine (13); B: hydralazine and propranolol (17); and C: hydralazine and pindolol (19)." | 5.08 | Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension. ( Holzberg, G; Insler, V; Mazor, M; Paran, E; Zmora, E, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 5.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| "In order to compare the long-term effects on ambulatory blood pressure and left ventricular hypertrophy of hydralazine and lisinopril we studied 30 patients, all males, still hypertensive (diastolic blood pressure > or = 95 mm Hg) despite combined beta-blocker/diuretic therapy and with echocardiographic evidence of left ventricular hypertrophy (left ventricular mass index > or = 1." | 5.08 | Effects of lisinopril vs hydralazine on left ventricular hypertrophy and ambulatory blood pressure monitoring in essential hypertension. ( Corradi, L; Fogari, R; Lusardi, P; Mugellini, A; Tettamanti, F; Zoppi, A, 1995) |
| "In patients with hypertension persisting on combined diuretic and beta-blocker therapy, the effects of an additional 9-week therapy with a calcium antagonist (nifedipine) versus a classical arterial vasodilator (hydralazine) were compared for changes in blood pressure (BP), plasma catecholamines (n = 15), and left ventricular (LV) systolic and diastolic function (n = 6)." | 5.06 | Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy. ( Burns, RJ; Frankel, D; Leenen, FH; Myers, MG, 1990) |
| " Eight white patients with mild essential hypertension were studied in a randomized, double-blind design to assess the effects of indomethacin on hydralazine's ability to lower blood pressure, elevate pulse, and alter the vascular prostacyclin biosynthesis as assessed by the urinary excretion of the major enzymatically produced metabolite of prostacyclin, 2,3-dinor-6-keto-prostaglandin F1 alpha (PGF1 alpha) measured by gas chromatography-mass spectrometry." | 5.06 | Hydralazine does not stimulate prostacyclin biosynthesis in hypertensive patients. ( Beckmann, ML; Byyny, RL; Gerber, JG; Loverde, M; Nies, AS, 1990) |
| "We report the results of a randomized, double-blind, parallel group multicentre study in 120 patients with moderate to severe hypertension, comparing two different types of antihypertensive treatment: a) the standard 'triple therapy' with hydrochlorothiazide, propranolol and hydralazine, and b) the combination of an ACE inhibitor, enalapril with hydrochlorothiazide (HCTZ) and methyldopa." | 5.06 | Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study. ( Ambrosioni, E; Cinotti, G; Cuspidi, C; Leonetti, G; Malini, PL; Morabito, S; Pessina, A; Rappelli, A; Sampieri, L; Semplicini, A, 1990) |
| "In a double-blind randomized study, hydralazine (n = 59) or the new dihydropyridine calcium antagonist felodipine (n = 61) was added to previous treatment with beta-adrenoceptor blocking agents in a group of 120 patients with essential hypertension." | 5.06 | Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy. ( Dahlöf, B; Gudbrandsson, T; Hansson, L; Hellsing, T; Kullman, S; Kuylenstierna, J; Leppert, J; Möller, B; Skogström, K; Svensson, A, 1988) |
| "The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension." | 5.06 | Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989) |
| "Endralazine and hydralazine were compared in a randomized double-blind, parallel group study lasting 1 year in 30 patients with essential hypertension inadequately controlled by a beta-blocker and a diuretic." | 5.06 | Comparative study of endralazine and hydralazine for the treatment of hypertension uncontrolled by a beta-blocker and diuretic. ( Chazan, BI; Duff, DA; McCallum, A; Whaley, K, 1986) |
| " Since left ventricular hypertrophy may be an important determinant of outcome in hypertension, the long-term effects of arterial vasodilation with hydralazine on left ventricular mass and function were compared with those of an alternative third-line drug, the alpha1 blocker prazosin, in patients still hypertensive despite combined diuretic and beta blocker therapy." | 5.06 | Vasodilators and regression of left ventricular hypertrophy. Hydralazine versus prazosin in hypertensive humans. ( Farkas, RM; Leenen, FH; Marquez-Julio, A; Reeves, RA; Smith, DL, 1987) |
| "To investigate the use of felodipine in severe hypertension 2 separate studies were carried out." | 5.06 | The use of felodipine in the treatment of severe hypertension. ( Muir, AL; Wathen, CG, 1987) |
| "Labetalol (Trandate; Allen & Hanburys), a combined alpha- and beta-adrenergic blocking agent, was compared with the more commonly used peripheral vasodilator, dihydrallazine (Nepresol; Ciba), each administered as an infusion, in the treatment of severe hypertension in 20 primigravidas at greater than or equal to 32 weeks' gestation." | 5.06 | Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy. ( Ashe, RG; Moodley, J; Philpott, RH; Richards, AM, 1987) |
| "The effects of graded doses of verapamil were compared with those of a combination of atenolol and hydralazine in a double-blind, randomised, crossover trial in 16 patients with essential hypertension." | 5.06 | Verapamil in essential hypertension: a comparison with atenolol plus hydralazine. ( Bailey, BP; Duggin, GG; Fletcher, PJ; Hall, B; Horvath, JS; Tiller, D, 1987) |
| "In 93 patients with hypertension uncontrolled by bendrofluazide 5 mg plus atenolol 100 mg daily, the effects of adding nifedipine (up to 60 mg/day, n = 31), prazosin (up to 20 mg/day, n = 31), or hydralazine (up to 200 mg/day, n = 31) were compared in a 6 month open random parallel group study." | 5.06 | Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker. ( Parnell, L; Ramsay, LE; Waller, PC, 1987) |
| "Forty-four consecutive patients referred for treatment because of hypertension (greater than 150/90 mmHg) occurring during pregnancy were randomly allocated to one of two treatment groups, hydralazine alone (n = 21) or hydralazine combined with pindolol (n = 23)." | 5.06 | Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol. ( Boner, G; Bott-Kanner, G; Friedman, S; Merlob, P; Nissenkorn, A; Ovadia, J; Paran, E; Reisner, S; Rosenfeld, J; Zmora, E, 1986) |
| "Forty-three patients with mild essential hypertension were randomized into two double-blind studies: pinacidil vs." | 5.06 | Antihypertensive efficacy of pinacidil--automatic ambulatory blood pressure monitoring. ( Collins, JB; Fisher, LD; Schirger, A; Sheps, SG; Shub, C; Spiekerman, RE; Zachariah, PK, 1986) |
| "Despite its approval in 1953, hydralazine hydrochloride continues to be used in the management of resistant hypertension, a condition frequently managed by nephrologists and other clinicians." | 5.05 | Genotype-Guided Hydralazine Therapy. ( Collins, KS; Cooper-DeHoff, RM; Eadon, MT; Elchynski, AL; Raviele, ALJ; Woodcock, AM; Zhao, Y, 2020) |
| "One-hundred and five patients with hypertension received nitrendipine (10-40 mg/day) or hydralazine (50-200 mg/day) in a double-blind randomized design." | 5.05 | Efficacy and safety comparison of nitrendipine and hydralazine as antihypertensive monotherapy. ( Deedwania, PC; Fagan, TC; Mehta, JL; Sternleib, C; Vlachakis, N, 1984) |
| "50 patients with confirmed hypertension were treated with endralazine, a new peripheral vasodilator, in addition to the beta-blocker, pindolol, to which they had not responded adequately." | 5.05 | Endralazine, a new peripheral vasodilator: absence of effect of acetylator status on antihypertensive effect. ( Bogers, WA; Holmes, DG; Huunan-Seppala, A; Wideroe, B; Wideroe, TE, 1983) |
| "This study of guanfacine in 27 patients suffering from moderate-to-severe hypertension showed a satisfactory blood pressure control in 26 patients." | 5.05 | Guanfacine alone and in combination therapy in the treatment of moderate and severe hypertension. ( Seedat, YK, 1983) |
| "The efficacy of a propranolol-hydralazine combination tablet was compared with that of each of its two components in the twice-daily treatment of mild to moderate essential hypertension (diastolic blood pressure: 100 to 125 mmHg)." | 5.05 | Propranolol-hydralazine combination in essential hypertension. ( Binstok, G; del Greco, F; Huang, C; Morledge, JH; Mullane, JF; Pittman, AW; Stevens, JD; Woods, JW, 1983) |
| "We report the results of an observer blind crossover trial in 31 patients with essential hypertension comparing the hypotensive effect of four doses of prazosin and of hydralazine used as the third step of triple therapy and additional data on the efficacy of low dose combinations of these two drugs." | 5.05 | Hydralazine and prazosin in the treatment of hypertension. ( Barnes, JN; Drew, PJ; Sharman, VL; Vandenburg, MJ; Wright, P, 1983) |
| "Despite the short plasma half-life of hydralazine, once daily Slow Apresoline has been shown to maintain blood pressure control in well controlled hypertension." | 5.05 | Evaluation of once daily hydralazine in inadequately controlled hypertension. ( Danielson, M; Kjellberg, J; Ohman, P; Wernersson, B, 1983) |
| "We compared the efficacy and safety of nitrendipine with that of hydralazine in 21 subjects with essential hypertension." | 5.05 | Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension. ( Aguila, E; Baz, R; Lopez, LM; Mehta, JL, 1984) |
| " A survey of 122 patients with resistant hypertension treated long-term with nifedipine and a control group of 102 similar patients treated with hydralazine revealed that nifedipine at an average dose of 40 mg daily caused a fall in blood pressure similar to that achieved with hydralazine in a dose of 86 mg daily." | 5.05 | Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients. ( Bulpitt, CJ; Dollery, CT; Murphy, MB, 1984) |
| "Patients with acute pregnancy-related hypertension were randomized to treatment with 200 mg oral labetalol or 10 mg intramuscular hydralazine." | 5.05 | Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared. ( Calder, AA; Greer, I; Walker, JJ, 1983) |
| "Prazosin was compared with hydralazine in 39 patients (mean age 49 years), who were already on beta-blockade for arterial hypertension." | 5.05 | Peripheral vasodilatation in the treatment of hypertension. Prazosin compared with hydralazine in patients not responding to beta-receptor blockade. ( Fagerberg, SE; Frithz, G; Malmberg, L, 1982) |
| "The effects of hydralazine formulation and dose interval were assessed in 20 patients with hypertension well controlled on conventional hydralazine tablets, 100 mg twice daily, in addition to atenolol and a diuretic." | 5.05 | Hydralazine once daily in hypertension. ( Freestone, S; Ramsay, LE; Silas, JH, 1982) |
| "1 Labetalol, an alpha- and beta- adrenoceptor blocking drug, was compared with acebutolol, alone or associated with dihydralazine in forty patients with moderate essential hypertension." | 5.05 | Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension. ( Corvol, P; Lardoux, MD; Thibonnier, M, 1980) |
| "The effect of a vasodilator (hydralazine), a beta-blocker (oxprenolol) and also their combination, on essential arterial hypertension and plasma renin activity (PRA), was studied." | 5.05 | Hydralazine and oxprenolol in the treatment of hypertension and the effect of these drugs on plasma renin activity. ( Siitonen, L, 1980) |
| "One hundred nineteen patients with essential hypertension (96 completing six months and 92 a one year study period) were randomized into four parallel groups and treated with one of four programs: 200 mg of metoprolol plus placebo; 200 mg of metoprolol plus 25 mg of hydrochlorothiazide; 200 mg of metoprolol plus 50 mg hydrochlorothiazide, or; 200 mg metoprolol plus 50 mg of hydralazine." | 5.05 | Clinical evaluation of the antihypertensive effect of metoprolol in combination with hydrochlorothiazide and hydralazine in an unselected hypertensive population. ( Honkavaara, M; Nissinen, A; Tuomilehto, J, 1980) |
| "Thirty-one patients with moderate and severe essential hypertension completed a comparative study of oxdralazine and dihydralazine." | 5.05 | Comparative study of oxdralazine and dihydralazine in essential hypertension. ( Criscuolo, D; Piazza, W; Salvadeo, A; Segagni, S; Villa, G, 1981) |
| " Two female and two male patients with essential hypertension were given dihydralazine plus saline or dihydralazine plus diclofenac intravenously on two separate occasions." | 5.05 | Are prostaglandins involved in the antihypertensive effect of dihydralazine? ( Frölich, JC; Ratge, D; Reimann, IW; Wisser, H, 1981) |
| "Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet." | 5.05 | Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension. ( Broughton Pipkin, F; Lamming, GD; Symonds, EM, 1980) |
| "In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy." | 5.05 | A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985) |
| " Control of hypertension was equivalent in both treatment groups, and in 64 (35%) cases hydralazine had to be added to the treatment to achieve the therapeutic goal (diastolic blood pressure below 85 mm Hg)." | 5.05 | Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa. ( Gallery, ED; Gyory, AZ; Ross, MR, 1985) |
| "The antihypertensive mechanisms of single and combined therapy with a beta-adrenergic antagonist (propranolol) and a vasodilator (hydralazine) were investigated in 9 patients with moderately severe hypertension, who were receiving maintenance diuretic (hydrochlorothiazide) treatment." | 5.05 | Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: hemodynamic and neuroendocrine mechanisms of action. ( Blomqvist, CG; Gaffney, FA; Graham, RM; Mulvihill-Wilson, J; Neal, WW; Pettinger, WA, 1985) |
| "In a series of 450 patients with mild essential hypertension, propranolol alone (P), propranolol plus hydrochlorothiazide (P+T), propranolol plus hydralazine (P+H), and propranolol plus hydrochlorothiazide plus hydralazine (P+T+H) were compared to reserpine plus hydrochlorothiazide (R+T)." | 5.04 | Propranolol in the treatment of essential hypertension. ( , 1977) |
| "Twenty-eight previously untreated patients with essential hypertension were included in a randomized double-blind cross-over study comparing the results of treatment with the established combination of a thiazide and methyldopa (regimen A) with the combination of a beta-receptor blocker and hydralazine (regimen B)." | 5.04 | Controlled clinical study on antihypertensive treatment with a diuretic and methyldopa compared with a beta-blocking agent and hydralazine. ( Hansen, M; Hansen, OP; Lindholm, J, 1977) |
| "The effect on hypertension of hydrochlorothiazide 100 mg daily plus timolol 20-60 mg daily versus hydrochlorothiazide plus placebo and of hydrochlorothiazide plus timolol plus hydralazine 40-200 mg daily versus hydrochlorothiazide plus placebo plus hydralazine was evaluated in a double-blind, randomized, crossover study in 38 patients with hypertension." | 5.04 | Effect of timolol plus hydrochlorothiazide plus hydralazine on essential hypertension. ( Alimadadian, H; Aronow, WS; Burwell, D; Greenfield, R; Mann, W; Van Herick, R, 1978) |
| " Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)." | 5.04 | The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978) |
| " The short term effects of hydrallazine, oxprenolol and oxprenolol plus hydrallazine were studied in five patients with essential hypertension." | 5.04 | Sympathetic reflex responses during treatment of essential hypertension with hydrallazine and oxprenolol. ( Davies, IB; Rosenthal, T; Sever, PS, 1979) |
| "Seventeen outpatients suffering from essential hypertension were treated in a double-blind cross-over study with labetalol or with a combination of propranolol and dihydrallazine." | 5.04 | Antihypertensive effect and plasma levels of labetalol. A comparison with propranolol and dihydrallazine. ( Allonen, H; Kleimola, T; Lehtonen, A, 1979) |
| "In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d)." | 5.04 | [Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)]. ( Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J, 1978) |
| "Thirty patients suffering from essential hypertension were treated successively with placebo, hydralazine alone, and pindolol (Visken) combined with hydralazine." | 5.04 | Combination therapy of essential hypertension with pindolol (Visken) and hydralazine. ( Persson, I, 1975) |
| "Ten patients not maximally controlled on an oxprenolo/cyclopenthiazide regimen for moderately severe hypertension were treated in a double blind crossover trial with either hydrallazine (75-150 mg/day) or phentolamine (60-120 mg/day) or placebo in addition to their other therapy." | 5.04 | Hydrallazine or phentolamine as adjuncts to beta-adrenoceptor blockade/thiazide therapy in hypertension. ( Kennedy, AC; McKillop, JH; Ward, DM; Winchester, JF, 1976) |
| " Twenty patients with severe or moderate hypertension were treated with minoxidil for 284 patient-months." | 5.04 | Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients. ( Dunea, G; Mahurkar, SD; Mamdani, B, 1976) |
| "Thirty patients suffering from essential hypertension were treated successively with placebo, hydralazine alone, and pindolol (Viskén) combined with hydralazine." | 5.04 | Combination therapy of essential hypertension with pindolol (Visken) and hydralazine. ( Persson, I, 1976) |
| "The cardiovascular effects of a new antihypertensive drug, bupicomide, were compared with those of hydralazine in 6 patients with mild to moderate hypertension." | 5.04 | Antihypertensive effect of a dopamine beta hydroxylase inhibitor, bupicomide: a comparison with hydralazine. ( Gilbert, CA; McNay, JL; Rutledge, CO; Velasco, M, 1975) |
| " Oral nifedipine is now considered an alternative first-line therapy, along with intravenous hydralazine and labetalol for women presenting with pre-eclampsia." | 4.98 | Focused Update on Pharmacologic Management of Hypertensive Emergencies. ( Broscious, R; Devabhakthuni, S; Noel, ZR; Watson, K, 2018) |
| "The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| " We present a case report of a premenopausal patient with hydralazine-associated amenorrhea." | 4.98 | Hydralazine-associated Amenorrhea in a Premenopausal Patient With Chronic Kidney Disease: A Case Report and Review of Literature. ( Al-Makki, A; Allspaw, A; Shepler, BM; Yeboah, KA, 2018) |
| "To quantify the effect of hydralazine compared to placebo in randomized controlled trials (RCTs) on all cause mortality, cardiovascular mortality, serious adverse events, myocardial infarctions, strokes, withdrawals due to adverse effects and blood pressure in patients with primary hypertension." | 4.87 | Hydralazine for essential hypertension. ( Kandler, MR; Mah, GT; Salzwedel, DM; Stabler, SN; Tejani, AM, 2011) |
| "To quantify the effect of hydralazine compared to placebo in randomized controlled trials (RCTs) on all cause mortality, cardiovascular mortality, serious adverse events, myocardial infarctions, strokes, withdrawals due to adverse effects and blood pressure in patients with primary hypertension." | 4.86 | Hydralazine for essential hypertension. ( Kandler, MR; Mah, GT; Stabler, SN; Tejani, AM, 2010) |
| "To review outcomes in randomised controlled trials comparing hydralazine against other antihypertensives for severe hypertension in pregnancy." | 4.82 | Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis. ( Cham, C; Magee, LA; Ohlsson, A; von Dadelszen, P; Waterman, EJ, 2003) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 4.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| " Hydralazine has been widely used in treatment of hypertension in eclampsia and preeclampsia, and its safety has been demonstrated in these patients." | 4.79 | Management of hypertensive urgencies and emergencies. ( Abdelwahab, W; Frishman, W; Landau, A, 1995) |
| "A 59-year-old man was diagnosed as having constrictive pericarditis 17 months after a typical hydralazine-induced autoimmune syndrome." | 4.79 | Hydralazine-induced constrictive pericarditis. ( el Gamal, MI; Franssen, CF; Gans, RO; Hoorntje, SJ, 1996) |
| "Recurrent episodes of postprandial hypoglycemic symptoms culminated in hypoglycemic coma in a hypertensive but otherwise healthy man while he was taking hydralazine." | 4.78 | Reactive hypoglycemic coma due to insulin autoimmune syndrome: case report and literature review. ( Burch, HB; Clement, S; Landry, F; Sokol, MS, 1992) |
| " Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects." | 4.77 | The evolution of antihypertensive therapy. ( Perry, HM, 1985) |
| " It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia." | 4.76 | Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984) |
| "Hydralazine, doxazosin, and verapamil are currently recommended by the Endocrine Society as acceptable bridging treatment in those in whom full cessation of antihypertensive medication is infeasible during screening for primary aldosteronism (PA)." | 4.31 | The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof. ( Alnazer, RM; de Leeuw, PW; Kroon, AA; Veldhuizen, GP, 2023) |
| "A 52-year-old Hispanic woman with a medical history of resistant hypertension treated with hydralazine 10 mg twice daily for 1 year presented with generalized weakness, dizziness, nausea, vomiting, and gross hematuria." | 4.31 | Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine. ( Agaronov, A; Akhondi, H; Bhatnagar, M; Pepito, D; Sarkisyan, E; Sotoudeh Deilamy, I, 2023) |
| "To compare the efficacy of intravenous Labetalol and intravenous Hydralazine in reduction of blood pressure in patients with severe pre-eclampsia." | 4.31 | Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women. ( Husain, S; Hussain, R; Kausar, M, 2023) |
| "This study aims to investigate the effect of the glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) liraglutide on retinal pathological findings as compared with insulin and hydralazine using an animal model of type 2 diabetes with obesity, hypertension, and hyperlipidemia." | 4.12 | Glucagon-like peptide-1 receptor agonist, liraglutide, attenuated retinal thickening in spontaneously diabetic Torii fatty rats. ( Hoshino, S; Inoue, K; Kamijo-Ikemori, A; Kimura, K; Watanabe, M; Yamada, S, 2022) |
| "A retrospective cohort study of patients with severe peripartum hypertension (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 110 mm Hg confirmed within 15 min) to determine whether the effectiveness of blood pressure control using nationally recommended medications (hydralazine, labetalol, nifedipine) differed by race/ethnicity." | 4.12 | Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension. ( Greene, NH; Kilpatrick, SJ; Pon, FF, 2022) |
| "Hydralazine, a widely used therapy for hypertension and heart failure, can elicit autoimmune disease, including anti-neutrophil cytoplasmic antibody associated glomerulonephritis (ANCA-GN)." | 4.02 | Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine. ( Appel, GB; Batal, I; Bomback, AS; Canetta, PA; D'Agati, VD; Kudose, S; Markowitz, GS; Radhakrishnan, J; Santoriello, D; Stokes, MB, 2021) |
| " The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death." | 3.96 | Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020) |
| "Hydralazine is a common vasodilator which has been used for the treatment of hypertension and heart failure." | 3.96 | Hydralazine-induced antineutrophil cytoplasmic antibody-associated vasculitis with pulmonary-renal syndrome: a case report. ( Al-Abdouh, A; Bekele, A; Garcia, P; Seid, H; Siyal, AM, 2020) |
| "Intravenous (IV) hydralazine, enalapril and labetalol are oftentimes used without indication for the treatment of asymptomatic hypertension in the hospital setting and have been shown to have substantial adverse effects that are associated with increased morbidity and mortality, as well as longer length of stay." | 3.91 | Improving the use of intravenous antihypertensive medications in the hospital setting: a quality improvement initiative for patient safety. ( Chams, N; Gjeka, R; Kumar, S; Peterson, D; Ross, I; Salman, A; Salman, J; Tegeltija, V, 2019) |
| "The aim of this study was to evaluate the use of as-needed (PRN) labetalol and hydralazine [intravenous (IV) or oral] in hospitalized medicine patients for the treatment of severe asymptomatic hypertension and to examine the potential negative outcomes associated with their use." | 3.88 | Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients. ( Gaynor, MF; Vondracek, S; Wright, GC, 2018) |
| "To explore the efficacy and safety of intravenous (IV) hydralazine in hospitalized children with hypertension." | 3.83 | Intravenous Hydralazine in Hospitalized Children and Adolescents with Hypertension. ( Bradford, MC; Flynn, JT; Harvey, EM, 2016) |
| "We report a rare case of Hydralazine-induced ANCA associated glomerulonephritis with alveolar hemorrhage in the setting of acute Clostridium Difficile Infection." | 3.83 | Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection. ( Cucu, DF; El Meligy, A; Rasla, S, 2016) |
| "This study aimed to compare the effects of labetalol, nicardipine, or hydralazine on time to target blood pressure before alteplase administration in patients with acute ischemic stroke." | 3.81 | Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine. ( Cortes, J; Hall, AB; McKay, C, 2015) |
| " Although both tempol and candesartan effectively reduced reactive oxygen species production in the kidney, tempol did not decrease blood pressure and exacerbated urine protein and histological damage, such as glomerulosclerosis and interstitial fibrosis, particularly in juxtamedullary nephrons (tempol vs." | 3.80 | Superoxide dismutase mimetic, tempol, aggravates renal injury in advanced-stage stroke-prone spontaneously hypertensive rats. ( Kohagura, K; Nakamura, T; Ohya, Y; Shinzato, T; Sugama, I; Yamazato, M, 2014) |
| " Hydralazine (direct vasodilator) or discontinuation of DOCA-salt treatment was used to assess the roles of systemic hypertension." | 3.80 | Roles of hypertension in the rupture of intracranial aneurysms. ( Hashimoto, T; Kitazato, KT; Kudo, M; Liang, EI; Makino, H; Murakami, S; Nagahiro, S; Shimada, K; Tada, Y; Wada, K, 2014) |
| "Hydralazine, a vasodilator used in resistant hypertension (RH) treatment is metabolized by an acetylation reaction mediated by N-acetyltransferase 2, the activity of which depends on NAT2 polymorphisms." | 3.80 | Different phenotypes of the NAT2 gene influences hydralazine antihypertensive response in patients with resistant hypertension. ( Muxfeldt, ES; Salles, GF; Santos, AR; Spinasse, LB; Suffys, PN, 2014) |
| "Hydralazine is a medication that has been used to manage hypertension and heart failure." | 3.80 | Hydralazine associated pauci-immune glomerulonephritis. ( Baiswar, S; Suneja, M; Vogelgesang, SA, 2014) |
| " In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension." | 3.78 | Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012) |
| " The prostaglandin E(2) receptor EP1 has been shown to contribute to hypertension by mediating angiotensin II-dependent vasoconstriction, although its precise role is incompletely characterized." | 3.78 | EP1 disruption attenuates end-organ damage in a mouse model of hypertension. ( Bartlett, CS; Boyd, KL; Breyer, RM; Harris, RC; Zent, R, 2012) |
| " Moreover, A779 treatment attenuated the reduction in MAP and proteinuria by either captopril (300 mg/L in drinking water) or hydralazine (1." | 3.77 | Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester. ( Al-Saleh, FM; Benter, IF; Chappell, MC; Diz, DI; Raghupathy, R; Yousif, MH, 2011) |
| "We have previously found that T lymphocytes are essential for development of angiotensin II-induced hypertension; however, the mechanisms responsible for T-cell activation in hypertension remain undefined." | 3.76 | Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. ( Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C, 2010) |
| " Another set of rats were treated with hydralazine (25 mg/kg per day orally) to determine the pressure-independent effects of HDAC inhibition on hypertension." | 3.76 | HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats. ( Cardinale, JP; Elks, CM; Francis, J; Guggilam, A; Mariappan, N; Pariaut, R; Sriramula, S, 2010) |
| " Therefore, olmesartan, an angiotensin type 1 receptor blocker, might affect oxidative stress in the brains of stroke-prone spontaneously hypertensive rats (SHRSP)." | 3.75 | Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. ( Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K, 2009) |
| "We report a case of hydralazine-induced alveolar hemorrhage and anti-neutrophil cytoplasmic antibody (ANCA)-positive pauci-immune glomerulonephritis, with serum anti-histone antibodies present, features not previously described in the literature with this drug." | 3.75 | Hydralazine-induced ANCA-positive pauci-immune glomerulonephritis: a case report and literature review. ( Dobre, M; Negrea, L; Wish, J, 2009) |
| " After 4 weeks of DOCA-salt hypertension, rats were either killed (n = 6), or treated with a non-hypotensive dose of spironolactone (n = 7) or triple therapy (hydrochlorothiazide, reserpine and hydralazine, n = 8) to normalize blood pressure or with vehicle (n = 19) for two further weeks." | 3.74 | Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension. ( Cordasic, N; Hartner, A; Hilgers, KF; Klanke, B; Schmieder, RE; Veelken, R, 2008) |
| " Despite comparable hypotensive effects between valsartan and hydralazine in salt-loaded SHRSP, valsartan reduced cerebral NADPH oxidase activity and ROS more than hydralazine being accompanied by more prevention of stroke by valsartan than hydralazine." | 3.74 | Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E, 2008) |
| " Sensitivity of VSCR control of efferent renal sympathetic nerve activity (RSNA) in SHR is restored when cardiac hypertrophy and hypertension are reduced by enalapril treatment." | 3.74 | Role of cardiac hypertrophy in reducing the sensitivity of cardiopulmonary reflex control of renal sympathetic nerve activity in spontaneously hypertensive rats. ( Abreu, GR; Bissoli, NS; de Andrade, TU; de Melo Cabral, A; Moysés, MR, 2008) |
| "To test the functional consequences of blocking the local renin-angiotensin system (RAS), we investigated the effects of an angiotensin II type 1 receptor blocker (ARB), candesartan, on the systemic gene expression profile of five important organs (brain, heart, kidney, liver and adipose tissues) in the stroke-prone spontaneously hypertensive rat (SHRSP), an established model of essential hypertension and cardiovascular disorders, and its normotensive control, the Wistar Kyoto (WKY) rat." | 3.74 | Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. ( Birukawa, N; Jesmin, S; Kato, N; Liang, YQ; Ochiai, Y; Serizawa, M, 2008) |
| " Azelnidipine, hydralazine, or vehicle was orally administered for 28 days to stroke-prone spontaneously hypertensive rats." | 3.74 | Azelnidipine decreases sympathetic nerve activity via antioxidant effect in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats. ( Araki, S; Hirooka, Y; Kishi, T; Koga, Y; Konno, S; Sunagawa, K, 2008) |
| "The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse established cardiovascular and renal alterations and oxidative stress was assessed in angiotensin II (AngII) hypertension." | 3.74 | Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. ( Delbosc, S; Jover, B; Mimran, A; Rugale, C, 2007) |
| " To test the general nature of this hypothesis, we examined whether similar changes in GluR1 density are found in a renovascular model of hypertension, the DOCA-salt rat, and if these changes are preventable by normalizing blood pressure with hydralazine, a peripherally acting vasodilator." | 3.74 | Sustained hypertension increases the density of AMPA receptor subunit, GluR1, in baroreceptive regions of the nucleus tractus solitarii of the rat. ( Aicher, SA; Andresen, MC; Bailey, TW; Hermes, SM; Lynch, PJ; McKee, BL; Mitchell, JL; Silverman, MB, 2008) |
| " We evaluated the effects of combining an angiotensin II type 1 (AT1) receptor blocker (ARB, valsartan) and a NEPI (CGS 25354) in comparison with a dual ACEI/NEPI (CGS 30440) in stroke-prone spontaneously hypertensive rats (SHRSP)." | 3.74 | Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP. ( Amiri, F; Brassard, P; Iglarz, M; Javeshghani, DM; Pu, Q; Schiffrin, EL; Webb, RL, 2008) |
| " Ischemia was induced by right femoral artery ligature in Wistar Kyoto rats (WKY) or spontaneously hypertensive rats (SHR) treated with or without angiotensin-converting enzyme inhibitor (Perindopril, 0." | 3.74 | Hypertension impairs postnatal vasculogenesis: role of antihypertensive agents. ( Cochain, C; Duriez, M; Lévy, BI; Loinard, C; Mees, B; Silvestre, JS; Vilar, J; You, D, 2008) |
| "We investigated whether gender differences in renal damage in DOCA-salt hypertension are associated with effects of ovarian hormones and/or endothelin-1 (ET-1)." | 3.73 | Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats. ( Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Mota, AL; Nigro, D; Tostes, RC; Zorn, TM, 2005) |
| "Azelnidipine suppressed cardiac hypertrophy, fibrosis, NADPH oxidase and superoxide in spSHRs more potently than amlodipine, and was associated with lower heart rates than amlodipine." | 3.73 | Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis. ( Ito, T; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T, 2006) |
| "The objectives were two-fold: (1) determine whether the use of hydralazine as antihypertensive therapy during obesity development exacerbated obesity-related cardioacceleration and hormonal abnormalities; (2) determine whether the absence of hypertension in obesity attenuated obesity-related abnormalities in hemodynamics, cardiac hypertrophy, and hormonal profile." | 3.72 | Hydralazine as antihypertensive therapy in obesity-related hypertension. ( Carroll, JF; Cohen, JS; King, JW, 2004) |
| "These studies determined the ability of AT1 receptor blockade or 'triple therapy', to reverse angiotensin II-induced hypertension and improve autoregulatory behavior." | 3.72 | Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation. ( Cook, AK; Imig, JD; Inscho, EW; Murzynowski, JB, 2004) |
| "Angiotensin II (Ang II) is a potent vasoconstrictor and induces inflammation and end-organ injury through its activation of the proinflammatory transcription factor, nuclear factor-kappaB (NF-kappaB)." | 3.72 | Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta. ( Chen, Y; Currie, RW; Ross, BM, 2004) |
| "The expression of HO-1 and iNOS in aorta increased with the SBP elevation during the development of SHR and was attenuated when the hypertension was lowered with the vasodilator hydralazine." | 3.72 | The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats. ( Chen, JJ; Cheng, PY; Yen, MH, 2004) |
| " Stroke-prone spontaneously hypertensive Izumo strain rats were divided into four groups, treated with vehicle, the angiotensin-converting enzyme inhibitor (ACEI) delapril (40 mg/kg per d), the angiotensin receptor antagonist (AT1R-Ant) candesartan cilexetil (1 mg/kg per d), or the vasodilator hydralazine (25 mg/kg per d) from weaning to puberty (3 to 10 wk of age), and then monitored without treatment for 6 mo." | 3.71 | Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis. ( Hayashi, M; Nakaya, H; Saruta, T; Sasamura, H, 2001) |
| "To clarify whether endothelium-derived contracting factor (EDCF) is developed in renal artery of hypertensive Dahl rats and whether prolonged oral L-arginine treatments prevent development of EDCF and hypertension." | 3.71 | L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats. ( Abe, Y; Chen, QH; Kosaka, H; Tian, RX; Yamamoto, A; Yoneyama, H; Zhang, L; Zhou, MS, 2001) |
| " To test whether accelerated atherosclerosis and aortic aneurysms were due to hypertension, we administered hydralazine to male apoE/eNOS DKO mice to reduce blood pressure." | 3.71 | Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice. ( Astern, J; Chen, J; Gyurko, R; Huang, PL; Kuhlencordt, PJ, 2001) |
| " Hydralazine prevented hypertension and arteriolar rarefaction in eNOS-/- mice, whereas capillary density was unaffected by treatment with the vasodilator." | 3.71 | Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme. ( Besnard, S; Feletou, M; Huang, PL; Kubis, N; Lévy, BI; Silvestre, JS; Tedgui, A, 2002) |
| "To evaluate the relation of tissue-localized angiotensin II (Ang II) concentration with cardiac hypertrophy and glomerulosclerosis in Tsukuba hypertensive mice (THM) carrying both human renin and angiotensinogen genes." | 3.70 | Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice. ( Fukamizu, A; Ishikawa, K; Kai, T; Kurooka, A; Murakami, K; Shimada, S; Sugimura, K; Takenaka, T, 1998) |
| "A novel model of hypertension recently developed in our laboratory shows that neonatal degeneration of capsaicin-sensitive sensory nerves renders a rat responsive to a salt load with a significant rise in blood pressure." | 3.70 | Antihypertensive mechanisms underlying a novel salt-sensitive hypertensive model induced by sensory denervation. ( Li, J; Wang, DH, 1999) |
| " The role of the renin-angiotensin system (RAS) in cardiac hypertrophy and nephropathy was examined in Tsukuba hypertensive mice (THM) carrying both human renin and angiotensinogen genes." | 3.70 | Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice. ( Ishikawa, K; Kai, T; Kurooka, A; Shimada, S; Sugimura, K, 1999) |
| " The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 3.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
| " The aim of this study was to compare the effects of an equivalent reduction in blood pressure produced by the angiotensin-converting enzyme (ACE) inhibitor spirapril (SPI) and an antihypertensive triple drug combination of hydralazine, reserpine and hydrochlorothiazide (HRH) on kidney function, proteinuria and renal structure in hypertensive diabetic rats." | 3.70 | Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats. ( Armini, L; Bardelli, M; Calci, M; Campanacci, L; Candido, R; Carretta, R; Fabris, B; Fazio, M; Fischetti, F, 1999) |
| " With the exception of one subject, all pre-eclamptics were taking clonidine (a known suppressant of rapid eye movement-REM-sleep) for control of their hypertension." | 3.70 | Pre-eclampsia is associated with marked alterations in sleep architecture. ( Blyton, CM; Edwards, N; Kesby, GJ; Sullivan, CE; Wilcox, I, 2000) |
| "Hypertension was induced in normotensive Wistar-Kyoto (WKY) rats by administration of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME), and blood pressure was lowered in stroke-prone spontaneously hypertensive rats (SHRSP) by administering hydralazine." | 3.69 | Plasma adrenaline responses to long-term modification of blood pressure in normotensive rats and hypertensive rats. ( Howe, PR; Jablonskis, LT, 1995) |
| "To investigate the influence of hypertension and of treatment with the vasodilator hydralazine or with the dihydropyridine calcium antagonist isradipine on the morphology of the thoracic aorta in spontaneously hypertensive rats (SHR)." | 3.69 | Influence of isradipine treatment on the morphology of the aorta in spontaneously hypertensive rats. ( Abbate, F; Amenta, F; Ciriaco, E; Ferrante, F; Laurà, R, 1994) |
| " Nifedipine is often used to control hypertension in kidney graft recipients." | 3.69 | Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994) |
| "To audit the use of bolus hydralazine for control of severe hypertension within a protocol for the management of severe pre-eclampsia." | 3.69 | Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia. ( de Swiet, M; Paterson-Brown, S; Redfern, N; Robson, SC; Walkinshaw, SA, 1994) |
| "A blunted reduction in total left ventricular load, due to increased pulsatile load in SHR treated with hydralazine, provided a hemodynamic basis for the differential regression of hypertrophy in this model of genetic hypertension." | 3.69 | Equipotent antihypertensive agents variously affect pulsatile hemodynamics and regression of cardiac hypertrophy in spontaneously hypertensive rats. ( Finn, PV; Mitchell, GF; Pfeffer, JM; Pfeffer, MA, 1996) |
| "Effects of benidipine hydrochloride or triple therapy (hydralazine, reserpine, and hydrochlorothiazide) on renal cortical and medullary intrinsic antioxidant enzyme (AOE) activity were evaluated in stroke-prone spontaneously hypertensive rats (SHR-SP) as an animal model for human essential hypertension with cerebral stroke." | 3.69 | Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP). ( Fukui, M; Shou, I; Takahashi, Y; Tomino, Y; Wang, LN, 1997) |
| "The present study evaluated the effects of lovastatin on renal function and the development of hypertension in spontaneously hypertensive rats (SHR)." | 3.69 | Lovastatin prevents development of hypertension in spontaneously hypertensive rats. ( Jiang, J; Roman, RJ, 1997) |
| "We compared the effects of long-term treatment with the angiotensin-converting enzyme inhibitor perindopril and triple therapy (hydrochlorothiazide, reserpine, and hydralazine) on the metabolic and renal features in the SHR/N-corpulent (cp) rat, a genetic model of non-insulin-dependent diabetes mellitus and hypertension." | 3.69 | Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat. ( Abraham, AA; Michaelis, OE; Scalbert, E; Striffler, JS; Thibault, N; Velasquez, MT, 1997) |
| "In blood pressure (BP) reduction induced by gallopamil, hydralazine and prazosin in patients with essential hypertension a common trend was found in renal prostanoid production which included increased TxB2 excretion and/or augmented TxB2/6-keto-PGF1alfa ratio and, with the exception of response to prazosin, enhanced PGF2alfa excretion." | 3.68 | TxA2-PGI2-PGF2 alfa responses in the kidney to blood pressure reduction induced by vasodilator/vasorelaxing agents with different action in patients with essential hypertension. ( Fehér, J; Gachályi, B; Juhász, I; Székács, B, 1993) |
| "Antihypertensive treatment with hydralazine for 10 weeks but not 6 weeks reduces infarct size in 13-week-old spontaneously hypertensive rats subjected to focal cerebral ischemia." | 3.68 | Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats. ( Slivka, A, 1993) |
| "The present study was designed to investigate the effect of nicardipine administration upon systolic blood pressure (SBP) and cardiac hypertrophy in spontaneously hypertensive rats (SHR)." | 3.68 | Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study. ( Amenta, F; Bronzetti, E; Ciriaco, E; Felici, L; Ferrante, F, 1992) |
| "The effects of enalapril and hydralazine upon left ventricular hypertrophy in SHRSP were consistent with their respective effects upon blood pressure." | 3.68 | Effects of enalapril and hydralazine treatment and withdrawal upon cardiovascular hypertrophy in stroke-prone spontaneously hypertensive rats. ( Cleary, EG; King, RA; Krishnan, R; Smith, RM, 1992) |
| "This study was designed to investigate the effects of antihypertensive drugs on vascular hypertrophy and vascular angiotensin II in vivo in spontaneously hypertensive rats (SHR)." | 3.68 | Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat. ( Higaki, J; Mikami, H; Morishita, R; Nagano, M; Nakamura, F; Ogihara, T; Tomita, N; Yu, H, 1992) |
| "We have compared the effects of the angiotensin converting enzyme inhibitor, perindopril, and a conventional antihypertensive regimen (triple therapy: hydralazine, reserpine and hydrochlorothiazide) on kidney function and albuminuria in hypertensive diabetic rats." | 3.68 | Antihypertensive therapy in a model combining spontaneous hypertension with diabetes. ( Allen, TJ; Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC; Rumble, JR, 1992) |
| " This study was undertaken in gravid ewes to determine the effects of treatment of cocaine-induced hypertension with hydralazine (Apresoline) on the maternal and fetal cardiovascular systems, catecholamine response, blood gas and acid-base status, and uterine blood flow (UBF)." | 3.68 | Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe. ( Espinoza, MI; Hughes, SC; Johnson, JL; Messer, CP; Parer, JT; Rosen, MA; Shnider, SM; Vertommen, JD, 1992) |
| "To evaluate the role of glomerular hypertension, glomerular hypertrophy, glomerular lipid deposition, and plasma cholesterol levels in diabetic glomerulopathy, Munich-Wistar rats received streptozocin and daily insulin injections and were assigned to one of three groups: untreated diabetic (DMC), hydralazine-treated diabetic (DMH), and enalapril-treated diabetic (DME)." | 3.68 | Glomerular abnormalities in long-term experimental diabetes. Role of hemodynamic and nonhemodynamic factors and effects of antihypertensive therapy. ( Fujihara, CK; Padilha, RM; Zatz, R, 1992) |
| "The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension." | 3.68 | Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991) |
| "7 years, mean +/- SD) received intravenous doses of labetalol, an alpha 1- and beta-adrenergic blocker, on 15 separate occasions for treatment of hypertension." | 3.68 | Intravenously administered labetalol for treatment of hypertension in children. ( Bunchman, TE; Lynch, RE; Wood, EG, 1992) |
| "To evaluate the efficacy and safety of intravenous hydralazine in arterial hypertension." | 3.68 | [Use of intravenous hydralazine in treatment of hypertensive crisis]. ( Amato, R; Bellotti, G; Cesar, LA; Pfeferman, E; Pileggi, F; Ramires, JA; Serrano, CV, 1991) |
| " Treatment of hypertension was begun at 3 months of age with cilazapril (45 mg/kg/day), an angiotensin converting enzyme (ACE) inhibitor, or with hydralazine (18 mg/kg/day)." | 3.68 | Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats. ( Baumbach, GL; Hajdu, MA; Heistad, DD, 1991) |
| "To test whether structural alterations observed in the mesenteric vasculature of Wistar-Kyoto spontaneously hypertensive rats (SHR) were dependent on the presence of hypertension, male SHR and Wistar-Kyoto normotensive (WKY) rats were treated in utero and postnatally with hydralazine up to 28 weeks of age." | 3.68 | Effect of hydralazine on the mesenteric vasculature of hypertensive rats. ( Lee, RM; Smeda, JS, 1991) |
| "Acute cocaine intoxication has been associated with elevated blood pressure and placental abruption." | 3.68 | Cocaine intoxication associated with abruptio placentae. ( Clark, JF; Flowers, D; Westney, LS, 1991) |
| "We compared the effects of the angiotensin-converting enzyme inhibitor enalapril and a conventional antihypertensive regimen (hydralazine and metoprolol) on kidney function, albuminuria, and glomerular ultrastructure in hypertensive diabetic and nondiabetic rats." | 3.68 | Nephropathy in model combining genetic hypertension with experimental diabetes. Enalapril versus hydralazine and metoprolol therapy. ( Allen, TJ; Clarke, BE; Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC; Papazoglou, D, 1990) |
| "In the 1950s, 223 white patients had varyingly severe hypertension controlled in hospital with ganglioplegic agent and hydralazine." | 3.67 | Survival of treated hypertensive patients as a function of compliance and control. ( Camel, GH; Perry, HM, 1984) |
| "The effect of guanfacine and hydrallazine on cardiovascular haemodynamics and on sympathetic nervous activity has been studied in 16 patients with essential hypertension." | 3.67 | Systemic and cardiac haemodynamic interactions between guanfacine and hydrallazine in hypertensive patients. ( Hernández, E; Hernández-Pieretti, O; Morillo, J; Ramirez, A; Urbina-Quintana, A; Velasco, M; Vizcarrondo, H, 1984) |
| "To determine if a remodeling of the collagen matrix would occur in the absence of hypertrophy and cell necrosis and if such a remodeling could alter active and passive stiffness of the intact myocardium, five rats with genetic hypertension (SHR) were treated (SHRT) with hydralazine for 32 weeks, beginning at four weeks of age, and compared to six age- and sex-matched SHR and seven Wistar-Kyoto genetic control rats (WKY)." | 3.67 | Myocardial collagen and mechanics after preventing hypertrophy in hypertensive rats. ( Janicki, JS; Narayan, S; Pick, R; Shroff, SG; Weber, KT, 1989) |
| " The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension." | 3.67 | Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report. ( Bar-Khayim, Y; Dgani, R; Lancet, M; Mogilner, BM; Nissim, F; Shoham, Z; Yemini, M, 1989) |
| " Treatment of the hypertension in the HT rats which hydralazine or propranolol restored the vascular relaxation response to Ach but not SNP; cGMP responses remained blunted." | 3.67 | The endothelium and cyclic guanosine monophosphate in hyperthyroid-induced hypertension. ( Hirt, E; Lockette, W; Otsuka, Y, 1987) |
| "The comparative effects of lisinopril, a third generation angiotensin converting enzyme (ACE) inhibitor, on components of the renin-angiotensin system were assessed in normal and in an animal model of diabetes-related hypertension, the streptozotocin-diabetic rat." | 3.67 | Effects of the angiotensin converting enzyme inhibitor, lisinopril, on normal and diabetic rats. ( Hartmann, JF; Hayes, NS; Keegan, ME; Slater, EE; Szemplinski, M, 1988) |
| "To investigate the relationship between cardiac hypertrophy associated with hypertension, and the alterations in myocardial lipid metabolism, nicardipine (160 mg/kg/day), hydralazine (40 mg/kg/day), and enalapril (30 mg/kg/day) were administered to spontaneously hypertensive rats from 20 to 24 weeks of age." | 3.67 | Fatty acid binding protein of cardiac muscle in spontaneously hypertensive rats: effect of hypertrophy and its regression. ( Fujii, S; Kawaguchi, H; Okamoto, H; Saito, H; Togashi, H; Yasuda, H, 1988) |
| "Echocardiography documented fetal premature atrial contractions after maternal hydralazine treatment for hypertension." | 3.67 | Fetal premature atrial contractions associated with hydralazine. ( Feinstein, SJ; Lodeiro, JG; Lodeiro, SB, 1989) |
| "A case of retroperitoneal fibrosis possibly associated with hydralazine, hydrochlorothiazide and ampicillin therapy is reported." | 3.67 | Hydralazine, hydrochlorothiazide and ampicillin associated with retroperitoneal fibrosis: case report. ( Waters, VV, 1989) |
| "Respiratory stridor and hoarseness were the predominant presenting symptoms in a 63-year-old woman with an hydralazine induced lupus syndrome." | 3.67 | Laryngeal manifestations of drug induced lupus. ( Maxwell, D; Silver, R, 1987) |
| "2 mg propranolol intravenously resulted in acute pulmonary edema." | 3.67 | Severe hypertension, propranolol, and acute pulmonary edema. ( Desai, SP; Fleming, TC; Pierce, EC, 1987) |
| " Prevention of the development of hypertension in SHR by hydralazine treatment from weaning did not increase pH or bicarbonate compared with untreated SHR, indicating that the metabolic acidosis in the SHR was not a consequence of raised blood pressure." | 3.67 | Disturbance of acid-base balance in the young spontaneously hypertensive rat. ( Drüeke, T; Lacour, B; Lucas, PA; McCarron, DA, 1987) |
| " Prevention of hypertension by hydralazine since the 4th wk of age did not alter the findings compared with the hypertensive SHR, suggesting calcium transport rates were unaffected by hypertension." | 3.67 | Ca fluxes across duodenum and colon of spontaneously hypertensive rats: effect of 1,25(OH)2D3. ( Gafter, U; Kathpalia, S; Lau, K; Zikos, D, 1986) |
| "As part of the Veterans Administration cooperative studies on antihypertensive agents, systolic time intervals (STIs) were recorded before and after 2 or 4 weeks of treatment with hydrochlorothiazide (HCTZ) alone in 320 asymptomatic patients with mild to moderate hypertension." | 3.67 | Serial measurements of systolic time intervals during treatment with hydrochlorothiazide alone and combined with other antihypertensive agents. ( Freis, ED; Kyle, MC, 1985) |
| "The hemodynamic changes after intravenous administration of hydralazine were assessed using M-mode echocardiography in 13 pregnant patients with severe hypertension." | 3.67 | Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension. ( Kuzniar, J; Piela, A; Skret, A; Szmigiel, Z; Zaczek, T, 1985) |
| " The development of hypertension in SHR rats were attenuated by treatment but none of the drugs was able to restore the impairment in isoproterenol, secretin and glucagon responsiveness of cardiac adenylate cyclase activity which is characteristic of these animals." | 3.66 | Comparative effects of alpha-methyldopa, propranolol and hydralazine therapy on cardiac adenylate cyclase activity in normal and spontaneously hypertensive rats. ( Camus, JC; Chatelain, P; Christophe, J; De Neef, P; Roba, J; Robberecht, P; Waelbroeck, M, 1981) |
| "Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 3.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
| "When administered to young spontaneously hypertensive rats (SHRs), dihydralazine (25 mg kg-1, daily) and captopril (100 mg kg-1, daily) prevent with the same efficacy genetic hypertension development (GHD)." | 3.66 | Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats. ( Freslon, JL; Giudicelli, JF, 1983) |
| " In order to study the relative roles of hypertension and cardiac hypertrophy in the depression of SHR function, 20-week old SHRs and normotensive rats were treated for 10 weeks with either hydralazine (100 mg X litre-1) or alpha-methyldopa (8 g X litre-1)." | 3.66 | Effect of antihypertensive therapy on calcium transport by cardiac sarcoplasmic reticulum of SHRs. ( Limas, CJ; Spier, SS, 1980) |
| "The uteroplacental blood flow was measured in 12 women with hypertension during pregnancy before and after intravenous injection of dihydralazine." | 3.66 | Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy. ( Lewander, R; Lunell, NO; Nylund, L; Sarby, B; Thornström, S, 1983) |
| "The influence of various disease states, other than hypertension, on the pharmacokinetic behaviour of hydralazine is not completely known." | 3.66 | Pharmacokinetics of oral hydralazine in chronic heart failure. ( Hanson, A; Johansson, BW; Wåhlander, LA; Wernersson, B, 1983) |
| "Thirty-three patients with essential hypertension and two with symptomatic arterial hypertension (Stage I-III) were treated for about two years with the drug obsilazin containing 50 mg propranolol and 50 mg dihydralazin per tablet (the maximum average dose of each drug was 174 mg/day)." | 3.66 | [Long-term treatment of arterial hypertension with a new combined preparation obsilazin]. ( Diuk, KD, 1983) |
| "Blood pressure, heart rate, and arterial diameter of the brachial artery were studied in patients with sustained essential hypertension before and after administration of three vasodilating drugs: dihydralazine, diltiazem, and dinitrate isosorbide (ISDN)." | 3.66 | Baroreflex response and vasodilating drugs in essential hypertension. ( Benetos, AM; Bouthier, JE; Levenson, JA; Safar, ME; Simon, AC, 1983) |
| "In 23 patients with primary hypertension, the efficacy and tolerability of slow-release hydralazine administered once daily were compared with those of conventional hydralazine given two to four times a day." | 3.66 | Efficacy and tolerability of hydralazine, in conventional and slow-release preparations, during long-term treatment of primary hypertension. ( Berglund, J; Eliasson, K; Lins, LE; Wernersson, B, 1983) |
| "26 patients with severe hypertension (10 essential, 9 renal parenchymatous, 7 renovascular) and a mean age of 42 years were treated with the new oral converting enzyme inhibitor captopril (SQ 14225)." | 3.66 | [Captopril in treatment-resistant hypertension (author's transl)]. ( Lüscher, T; Siegenthaler, W; Studer, A; Vetter, W, 1980) |
| "The effects on the fetus of the acute lowering of blood pressure in maternal hypertension with dihydralazine 6." | 3.66 | The effect of low-dose dihydrallazine on the fetus in the emergency treatment of hypertension in pregnancy. ( Moodley, J; Vink, GJ, 1982) |
| " To determine the effects of antihypertensive drugs on heart rate and blood velocity 15 patients with hypertension were treated with placebo, hydrochlorothiazide, nadolol, propranolol and hydralazine in sequence." | 3.66 | Effects of antihypertensive agents on blood velocity: implications for atherogenesis. ( Spence, JD, 1982) |
| "The concentration of "real" and "apparent" (= "real" hydralazine + acid-labile hydrazones) hydralazine in maternal and umbilical plasma obtained at delivery of 6 women treated with hydralazine and atenolol for pregnancy hypertension were measured by gas chromatography." | 3.66 | Transplacental passage and breast milk concentrations of hydralazine. ( Hanson, A; Ingemarsson, I; Liedholm, H; Melander, A; Wåhlin-Boll, E, 1982) |
| "Three patients developed hepatic injury two months, ten months and two years, respectively, after hydralazine therapy for hypertension." | 3.66 | Hydralazine-induced hepatitis. ( Ichinoe, A; Itoh, S; Itoh, Y; Tsukada, Y, 1981) |
| "A combination of propranolol and hydrallazine was administered to 13 patients with longstanding hypertension during 15 pregnancies." | 3.66 | Propranolol and hydrallazine in the management of essential hypertension in pregnancy. ( Bott-Kanner, G; Joel-Cohen, SJ; Reisner, SH; Rosenfeld, JB; Schweitzer, A, 1980) |
| "Oxdralazine, a pyridazine shown to induce prolonged arteriolar dilation in animals, was given orally in doses of 15 to 30 mg to 7 subjects with hypertension." | 3.66 | Hemodynamic effects of oxdralazine and hydralazine in hypertension. ( Cohn, JN; Moskowitz, RM, 1980) |
| "The efficacy of labetalol in lowering blood pressure was assessed in 18 patients with chronic renal failure and hypertension." | 3.66 | Labetalol in the treatment of hypertensive renal patients. ( Craswell, PW; De Voss, K; Williams, JG, 1978) |
| " Nine patients with essential hypertension were studied during administration of prazosin, hydralazine or placebo." | 3.66 | Unimpaired beta adrenergic responses during prazosin administration. ( Buzzeo, LA; Lowenstein, J; Steele, JM, 1979) |
| "A regimen consisting of chlorthalidone, hydralazine and propranolol would be useful in some hypertensive patients with coronary artery disease or aortic dissection if it could be shown that reflex cardiac stimulation induced by hydralazine is completely neutralized by propranolol." | 3.66 | Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance. ( Belasco, RN; Moyer, JP; Pittman, AW; Woods, JW, 1979) |
| "The effect of long-term treatment of hypertension with propranolol, alone or in combination with hydrochlorothiazide and/or dihydralazine, was investigated in 93 patients with various types of hypertension." | 3.66 | [Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine]. ( Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC, 1978) |
| "Eleven patients with essential hypertension were given hydralazine (25 mg b." | 3.66 | Renal plasma flow and cardiac output during hydralazine and propranolol treatment in essential hypertension. ( Falch, DK; Norman, N; Odegaard, AE, 1978) |
| "In 16 patients with hypertension, BP could not be controlled satisfactorily by treatment with propranolol alone (mean dosage 325 mg/day)." | 3.66 | Changes in plasma volume and extracellular fluid volume and after addition of hydralazine to propranolol treatment in patients with hypertension. ( Ibsen, H; Jensen, HA; Leth, A; Rasmussen, K, 1978) |
| " To determine if the enhanced sympathetic response to PH stimulation seen in adult SHR is an intrinsic difference rather than secondary to sustained hypertension, we maintained SHR normotensive from four weeks of age with antihypertensive drug therapy (clonidine or hydralazine)." | 3.66 | Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto rats. ( Juskevich, JC; Robinson, DS; Whitehorn, D, 1978) |
| " Budralazine was orally effective against various types of hypertension in rats and it, like reserpine but unlike hydralazine, produced a much greater pressure reduction in hypertensive than in normotensive rats." | 3.66 | Pharmacology of budralazine, a new antihypertensive drug. ( Akashi, A; Chiba, T; Hashimoto, H; Suzuki, I, 1978) |
| "A reversible syndrome resembling systemic lupus erythematosus and induced by hydralazine hydrochloride therapy is a well-recognized phenomenon in adults but does not seem to have been reported in children." | 3.65 | Hydralazine-induced lupus erythematosus-like syndrome. ( Irias, JJ, 1975) |
| "During phenylephrine-induced hypertension in 6 near-term pregnant ewes, nitroprusside rapidly lowered the blood pressure to control values with no accompanying change in uterine blood flow." | 3.65 | Comparison of nitroprusside and hydralazine in hypertensive pregnant ewes. ( Krames, E; Levinson, G; Ring, G; Shnider, SM; Wallis, KL, 1977) |
| "Plasma renin concentration (PRC) was measured in 46 patients with essential hypertension before and after treatment for 4 weeks with alprenolol 600-1200 mg daily." | 3.65 | Plasma renin concentration in essential hypertension during beta-adrenergic blockade and vasodilator therapy. ( Kornerup, HJ; Pedersen, EB, 1977) |
| "This paper presents experience with the treatment of mild to moderate hypertension by means of a thiazide diuretic (cyclopenthiazide), a small dose of a beta adrenergic blocking agent (oxprenolol) and progressively increasing doses of a vasodilator (hydrallazine)." | 3.65 | Diuretics, beta blockers and vasodilators. Dosage in mild and moderate hypertension. ( Goble, AJ, 1975) |
| "Twenty-three out-patients with mild or moderate essential hypertension have been treated with a combination of hydralazine (37." | 3.65 | Acetylator phenotype and the antihypertensive response to hydralazine. ( Jounela, AJ; Mattila, MJ; Pasanen, M, 1975) |
| "Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13." | 3.65 | Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975) |
| "The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension." | 3.65 | Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975) |
| "A patient with severe progressive hypertension was treated with parenteral hexamethonium and large dosages of hydralazine." | 3.65 | Persistent reversal of severe systemic hypertension after prolonged toxic reaction to hydralazine. ( Abrams, DL; Kaplan, BM; Miller, AJ, 1975) |
| "Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | 3.63 | Hexamethonium and hydralazine hydrochloride for treatment of hypertension. ( STUPPY, LJ, 1954) |
| " Initial dosing with nicardipine lowered acute diastolic BP than labetalol (least square mean difference (labetalol-nicardipine)=5." | 3.11 | Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage. ( Behymer, TP; Bettin, M; Christianson, T; Coleman, ER; Divani, A; Flaherty, ML; Gilkerson, LA; James, ML; King, NKK; Krishnamoorthy, V; Langefeld, CD; McCauley, JL; Ng, Y; Qi, W; Shah, S; Testai, FD; Walsh, KB; Woo, D, 2022) |
| " Among blacks with hypertensive chronic kidney disease, neither PM (bedtime) dosing of once-daily antihypertensive nor the addition of drugs taken at bedtime significantly reduced nocturnal BP compared with morning dosing of antihypertensive medications." | 2.78 | A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease. ( Agodoa, LY; Appel, LJ; Bakris, GL; Charleston, J; Contreras, G; Gabbai, F; Greene, T; Hiremath, L; Jamerson, K; Kendrick, C; Kusek, JW; Lash, JP; Lea, J; Miller, ER; Phillips, RA; Rahman, M; Rostand, S; Toto, R; Wang, X; Wright, JT, 2013) |
| "Established hypertension is associated with abnormal exercise hemodynamics and reduced exercise capacity through mechanisms that may include contributions from arterial stiffness and endothelial vasomotor dysfunction." | 2.78 | Phosphodiesterase type 5 inhibition improves arterial stiffness after exercise but not exercise capacity in hypertensive men. ( Attinà, TM; Drummond, ID; Malatino, LS; Maxwell, SR; Webb, DJ, 2013) |
| " Full-text, English-language articles describing IV labetalol and/or hydralazine use for non-emergent HTN in an inpatient setting that focused on clinical outcomes (ie vitals, adverse effects, healthcare utilisation) were included." | 2.72 | Safety and efficacy of intravenous hydralazine and labetalol for the treatment of asymptomatic hypertension in hospitalised patients: A systematic review. ( Cawoski, JR; Covvey, JR; DeBiasio, KA; Donnachie, SW; Guarascio, AJ; Montepara, CA; Nemecek, BD; Timanus, EA; Zimmerman, DE, 2021) |
| "Untreated essential hypertension is associated with left ventricular hypertrophy (LVH) and structural changes in resistance vessels." | 2.68 | Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril. ( Aalkjaer, C; Holm, M; Lederballe, O; Mulvany, M; Mørn, B; Schroeder, AP; Sihm, I; Thygesen, K, 1995) |
| "Arterial hypertension is frequently associated with serum lipid abnormalities." | 2.68 | Factors affecting lipoprotein lipase in hypertensive patients. ( Annuzzi, G; D'Orta, G; Di Marino, L; Ferrara, LA; Lucarelli, C; Mancini, M; Marotta, T; Rossi, F; Russo, O, 1995) |
| "Hydralazine is a vasodilator antihypertensive drug that has been in use for many years." | 2.67 | Effect of food on oral availability of apresoline and controlled release hydralazine in hypertensive patients. ( Jackson, SH; Jamieson, MJ; Ludden, LK; Ludden, TM; Muir, KT; Rogers, D; Shepherd, AM; Woodworth, J, 1990) |
| " Although designed as a titration study, important dose-response data were available for analysis with nonlinear mixed effect modeling (NONMEM)." | 2.67 | Hydralazine dose-response curve analysis. ( Chang, I; Graves, DA; Muir, KT; Patel, B; Richards, W; Steiger, BW, 1990) |
| "Hydralazine was found to be superior in its ability to effect more rapidly a lower mean arterial blood pressure." | 2.66 | Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension. ( Griffis, KR; Martin, JN; Martin, RW; Morrison, JC; Palmer, SM, 1989) |
| "The felodipine treated patients experienced more ankle swelling and flushing than those in the hydralazine group who experienced more headache and minor gastro-intestinal upset." | 2.66 | Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group. ( , 1986) |
| " The duration of action also varied in the labetalol group, with the shortest duration occurring in those patients who required the highest dosage for BP control." | 2.66 | A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy. ( Amon, E; Gonzalez, AR; Mabie, WC; Sibai, BM, 1987) |
| "Hydralazine was begun after a two-week to four-week period in which blood pressure was not adequately controlled with diuretics alone." | 2.66 | Comparative efficacy and safety of immediate-release and controlled-release hydralazine in black hypertensive patients. ( Adir, J; Curry, CL; Janda, SM; Poku, CD; Rotenberg, KS; Taylor, RE, 1987) |
| "Carvedilol was evaluated acutely with invasive (dye-dilution) and noninvasive (plethysmography) technique and showed an acute antihypertensive effect without causing a rise in TPR and with a decrease in regional resistance in the fore-arm." | 2.65 | Beta-adrenoceptor blockade and vasodilatation in essential hypertension. Hemodynamic studies at rest and during exposure to stress. ( Eggertsen, R, 1984) |
| " Apart from the hydrochlorothiazide dosage which was fixed, the dosage of the other active drugs was titrated incrementally until the target blood pressure level was achieved." | 2.65 | An appraisal of antihypertensive efficacy and adverse reactions with two drug regimens: enalapril maleate as part of triple therapy compared to conventional triple therapy in moderate to severe hypertension. ( Fernandez, PG; Galway, AB; Kim, BK, 1984) |
| "Atenolol was withdrawn in those allocated to labetalol, and minoxidil was given only to men." | 2.65 | "Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic. ( Latham, L; Lorimer, AR; McAreavey, D; McLaren, AD; Ramsey, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ, 1984) |
| "The possibility to apply impedance cardiography technique and individual statistical analysis based on Dixon's criterion to pharmacodynamic studies of single hydralazine ( apressine ), prazosine ( pratsiol ), endralazine ( mirethilan ), propranolol (obsidan) doses is discussed." | 2.65 | [Methodologic approach to individual evaluation of the pharmacodynamic effects of single doses of hydralazine, endralazine, prazosine and propranolol in hypertension patients]. ( Izotov, AI; Postol'nikov, SF; Vygodin, VA, 1984) |
| "Labetalol pre-treatment especially seemed to enhance the effect of subsequent propranolol/hydralazine administration." | 2.65 | Comparison of labetalol, propranolol and hydralazine in hypertensive out-patients. ( Donker, AJ; May, JF; ten Berge, BS; van der Veur, E; Wesseling, H, 1982) |
| "The optimal daily dose and dose regimen of a new drug combination (Pertenso), consisting of 10 mg bemetizide, 20 mg triamterene, 20 mg dihydralazine and 20 mg bupranolol were tested in 14 hypertensive outpatients (WHO I to III) in a single blind crossover trial." | 2.65 | [Treatment of hypertension with a drug combination, consisting of bemetizide, triamterene, dihydralazine and bupranolol (author's transl)]. ( Brandstetter, G; Gasser, RW; Skrabal, F, 1982) |
| "The incidence of preeclampsia in the randomized prophylactic antihypertensive group was statistically lower than that in the nonrandomized group (8." | 2.65 | The effects of prophylactic management and therapeutics on hypertensive disease in pregnancy: preliminary studies. ( Crenshaw, MC; Dorminy, JH; Gall, SA; Jelovsek, FR; Welt, SI, 1981) |
| "Blood pressure (BP) control and tolerability of three two-week dosage regimens of hydralazine--conventional hydralazine q." | 2.65 | Hydralazine in arterial hypertension. Randomized double-blind comparison of conventional/Slow-Release formulation and of b.i.d./q.i.d. dosage regimens. ( Holst, B; Krogsgaard, AR; Lenz, K; Wulff, K, 1980) |
| "Evidence of cardiac hypertrophy was slow to resolve despite good control of blood pressure." | 2.64 | Double-blind comparison of minoxidil and hydrallazine in severe hypertension. ( Bennett, CM; Connor, G; Wilburn, RL, 1976) |
| " In the dosage used, hydrallazine affected only the diastolic blood pressure, and when added to either bendrofluazide or bendrofluazide plus atenolol it produced a further mean reduction in pressure of 6 mm Hg." | 2.64 | Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension. ( Mitchell, JR; Wilcox, RG, 1977) |
| "Labetalol is a useful hypotensive drug with effect similar to that of a combination of a beta-adrenoceptor blocking drug and a vasodilator." | 2.64 | Labetalol compared with prindolol plus hydraliazine in the treatment of hypertension: a double-blind cross-over study. ( Barnett, AJ; Guest, C; Kalowski, S, 1978) |
| " The mean coefficient of variation for the 2 days prior to initiation of hydralazine dosing was 4." | 2.64 | Duration of hydralazine action in hypertension. ( Boles, M; Dayton, PG; Israili, ZH; McNay, JL; O'Malley, K; Segal, JL, 1975) |
| "Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants." | 2.61 | Neonatal hypertension: cases, causes, and clinical approach. ( Flynn, JT; Starr, MC, 2019) |
| "Heart failure affects more than 6 million people in the United States and incurs a heavy toll in morbidity, mortality, and health care costs." | 2.58 | Heart Failure. ( Wu, A, 2018) |
| "Hypertension is a major risk factor for cardiovascular disease, but control of hypertension remains inadequate, often because of poor patient adherence to prescribed medical regimens that are viewed as poorly tolerated and expensive." | 2.47 | Older blood pressure medications-do they still have a place? ( Black, HR; Slim, HB; Thompson, PD, 2011) |
| "Perioperative hypertension is commonly encountered in patients that undergo surgery." | 2.44 | Perioperative hypertension management. ( Marik, PE; Varon, J, 2008) |
| "Heart failure is a substantial cause of increased morbidity and mortality in the African-American population, with poorer prognosis versus white patients." | 2.41 | Contemporary treatment of heart failure: is there adequate evidence to support a unique strategy for African-Americans? Con position. ( Ferdinand, DP; Ferdinand, KC; Serrano, CC, 2002) |
| "Management of preeclampsia is bed rest, aspirin administration, antihypertensive agents (beta-blockers, hydralazine, alpha-methyldopa) would be used for reduction of blood pressure." | 2.40 | [Pregnancy induced hypertension]. ( Suzuki, H, 1997) |
| "Therefore, for the treatment of hypertension it is important to understand the mechanism of cardiac hypertrophy and to establish effective pharmaceutical interventions." | 2.40 | Role of the renin-angiotensin system in cardiac hypertrophy. ( Komuro, I; Yamazaki, T; Yazaki, Y, 1999) |
| "Antihypertensive agents have been associated with adverse reactions that, if unrecognized by health practitioners, may have devastating consequences." | 2.38 | Fatal hepatotoxicity induced by hydralazine or labetalol. ( Stumpf, JL, 1991) |
| "Hypertension in pregnancy has implications for both maternal and fetal welfare." | 2.37 | Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984) |
| "Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy." | 2.37 | Hypertension in pregnant women. ( Gallery, ED, 1985) |
| "Although drug treatment of hypertension is associated with improved survival and decreased vascular complications, drug compliance is a major problem in the control of hypertension." | 2.36 | Antihypertensive pharmacology. ( Freed, CR; Gerber, JG; Nies, AS, 1980) |
| "Amlodipine was the most common first-line agent (n=10), followed by hydralazine (n=4) and hypertonic saline (n=1)." | 1.72 | Evaluation of presentation, treatment and outcome in hypertensive emergency in dogs and cats: 15 cases (2003-2019). ( Beeston, D; Cortellini, S; Jepson, R, 2022) |
| "Hydralazine is a commonly prescribed antihypertensive agent." | 1.62 | Hydralazine-induced liver injury: a review and discussion. ( Bhardwaj, M; Bhardwaj, NJ; Cueto, K; Killeen, TC, 2021) |
| "Magnesium sulfate was promptly administered on admission to every woman to prevent seizure." | 1.56 | Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women. ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020) |
| "Hypertension is an important risk factor for nonalcoholic steatohepatitis." | 1.56 | The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension. ( Asano, T; Hashimoto, S; Kitamori, K; Naito, H; Nakajima, T; Yuan, Y, 2020) |
| "Hypertension was induced in uninephrectomized control rats (UNx) by subcutaneous implantation of a DOCA pellet plus administration of 1% NaCl in the drinking water (DOCA-salt) for 3 wk." | 1.43 | Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats. ( Cha, H; Cook, AK; Guan, Z; Inscho, EW; Pollock, DM; Pollock, JS; Singletary, ST; Van Beusecum, JP, 2016) |
| "Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats." | 1.43 | Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016) |
| "Hypertension is a powerful risk factor of atrial fibrillation (AF)." | 1.42 | Blockade of brain angiotensin II type 1 receptor inhibits the development of atrial fibrillation in hypertensive rats. ( Chishaki, A; Hirooka, Y; Inoue, S; Kishi, T; Mukai, Y; Nagayama, T; Sunagawa, K; Takase, S; Takemoto, M, 2015) |
| "Renal fibrosis was increased 2." | 1.42 | A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD Progression. ( Bin, W; Cao, W; Hou, FF; Li, A; Su, Z; Wang, L; Wilcox, CS; Zhou, Z, 2015) |
| "Aliskiren treatment almost completely suppressed angiotensin I and resulted in lower angiotensin II concentration than ramipril treatment." | 1.40 | Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading. ( Ayuzawa, N; Fujita, T; Ishizawa, K; Kawarazaki, W; Nagase, M; Takeuchi, M; Ueda, K; Yoshida, S, 2014) |
| " Demographic data and data on adverse effects (AE), BP, and heart rate (HR) prior to and after each first dose were collected." | 1.40 | The efficacy and safety of intravenous hydralazine for the treatment of hypertension in the hospitalized child. ( Chessman, K; Egan, B; Hailpern, SM; Jones, J; Ostrye, J; Shatat, IF, 2014) |
| "Hydralazine pretreatment reversed DE-induced TF, tPA, TNF-α, and MMP-2 expression but not eNOS, RAGE, and HMGB-1." | 1.39 | Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention. ( Andrews, D; Bass, V; Gilmour, MI; King, C; Kodavanti, UP; Krantz, QT; Ledbetter, AD; Nyska, A; Richards, JE; Schladweiler, MC; Thomas, RF, 2013) |
| "We report a case of posterior reversible encephalopathy syndrome (PRES) in a 73-yr-old woman with a history of uncontrolled hypertension who had recently discontinued one of her antihypertensive drugs; such cases are rare but pose a diagnostic challenge given the nonspecific nature of the clinical presentation." | 1.39 | Posterior reversible encephalopathy syndrome: 'a headache' on the AMU. ( Bholah, MH; Desai, P; Dunn, E, 2013) |
| "Postpartum preeclampsia/eclampsia is the presence of hypertension and proteinuria, with or without seizures, occurring up to 4 weeks after delivery." | 1.37 | Postpartum preeclampsia: emergency department presentation and management. ( Abbott, J; Bakes, K; Withers, E; Yancey, LM, 2011) |
| "Both medications prevented left ventricle remodeling, but olmesartan improved cardiomyocyte hypertrophy better than hydralazine." | 1.35 | Favorable cardiac and aortic remodeling in olmesartan-treated spontaneously hypertensive rats. ( de Souza Mendonça, L; Fernandes-Santos, C; Mandarim-de-Lacerda, CA, 2009) |
| "They developed more left ventricular hypertrophy and more renal hypertrophy after 6 weeks of DOCA-salt+hydralazine compared with female mice." | 1.35 | Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism. ( Akashi, YJ; da Costa Goncalves, AC; de Windt, LJ; Dragun, D; Gross, V; Gürgen, D; Hegner, B; Karatas, A; Kintscher, U; Luft, FC; Regitz-Zagrosek, V; Schubert, C, 2008) |
| "Hypertension is an important risk factor associated with development and progression of diabetic retinopathy (DR)." | 1.34 | Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats. ( Biswas, SK; de Faria, JB; de Faria, JM; Pinto, CC; Silva, KC; Souza, DS, 2007) |
| "Captopril treatment significantly reduced cardiac mass (3." | 1.33 | Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats. ( Gupta, S; Sen, S; Young, D, 2005) |
| "Losartan was the only treatment that induced alpha1 subunit expression." | 1.33 | Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats. ( Amiri, F; Brassard, P; Schiffrin, EL; Thibault, G, 2006) |
| " In conclusion, our findings suggested that chronic administration of olmesartan ameliorated the endothelial dysfunction in L-NAME-treated rats." | 1.33 | Effects of angiotensin II type 1 receptor blockade on the systemic blood nitric oxide dynamics in Nomega-nitro-L-arginine methyl ester-treated rats. ( Abe, S; Ishihara, M; Ishizawa, K; Izawa, Y; Kanematsu, Y; Kawazoe, K; Motobayashi, Y; Ohnishi, H; Tamaki, T; Tsuchiya, K, 2006) |
| "Hydralazine-treated SHR had normalized blood pressure but unaltered low ICP response." | 1.33 | Increased intracavernosal pressure response in hypertensive rats after chronic hemin treatment. ( Shamloul, R; Wang, R, 2006) |
| "Treatment with losartan, captopril, and the TRx prevented the rhEPO-induced increased in systolic BP." | 1.33 | Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin. ( Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME, 2006) |
| "In nitrendipine-treated rats, EOD score was closely related to long-term systolic BPV (r = 0." | 1.32 | Contribution of blood pressure variability to the effect of nitrendipine on end-organ damage in spontaneously hypertensive rats. ( Chu, ZX; Liu, JG; Miao, CY; Su, DF; Xu, LP, 2003) |
| "Uremia was induced in male Spraugue Dawley rats by 5/6 nephrectomy." | 1.32 | Gene expression in uremic left ventricular hypertrophy: effects of hypertension and anemia. ( Chang, SL; Draksharapu, A; Mak, RH; Pak, YK, 2004) |
| "Hypertension is the main cause of stroke that represents the second most common cause of death in the industrialized world and a leading cause of inability of the elderly." | 1.31 | Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats. ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001) |
| "Cardiac hypertrophy was reduced by all three treatments, but to a lesser extent by hydralazine (treatment study), and this regression of cardiac hypertrophy persisted only with both types of RAS inhibition (withdrawal study)." | 1.31 | Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats. ( Paull, JR; Widdop, RE, 2001) |
| "cytisine were still greater in SHR." | 1.31 | Spinal nicotinic receptor activity in a genetic model of hypertension. ( Khan, IM; Printz, MP; Stanislaus, S; Taylor, P; Vaughn, D; Yaksh, TL; Zhang, L, 2001) |
| "Pretreatment with indomethacin did not affect the cardiovascular effect of GR138950 in conscious RALH rats." | 1.30 | Investigation of the inhibitory effect of N(G)-nitro-L-arginine methyl ester on the antihypertensive effect of the angiotensin AT1 receptor antagonist, GR138950. ( Anderson, IK; Drew, GM, 1997) |
| "After 20 days of treatment, proteinuria had only increased to 1,272 +/- 135 mg/kg/day, a reduction of 45% compared to the untreated control group (2,300 +/- 346 mg/kg/day; p < 0." | 1.30 | Endothelin-A receptor antagonist combined with hydralazine improves survival and renal function in hypertensive rats. ( Hergenröder, S; Kirchengast, M; Münter, K, 1998) |
| "Vascular and cardiac hypertrophy were significantly attenuated with losartan or perindopril, but were unchanged with other treatments." | 1.30 | Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis. ( Anderson, NH; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; Morton, JJ; Reid, JL; Schork, NJ, 1999) |
| "In captopril-treated SHR preparations, PNS evoked significantly larger CGRP-like immunoreactive release than in non-treated SHR." | 1.30 | Long-term treatment with angiotensin converting enzyme inhibitor restores reduced calcitonin gene-related peptide-containing vasodilator nerve function in mesenteric artery of spontaneously hypertensive rats. ( Araki, H; Gomita, Y; Kawasaki, H; Mimaki, Y; Nakatsuma, A; Okazaki, M, 1999) |
| "Perindopril treatment also effectively prevented the development of vascular hypertrophy; however, treatment with hydralazine and hydrochlorothiazide was not as effective despite equivalent blood pressure reduction." | 1.30 | Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27. ( Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Mullins, JJ, 1999) |
| " A low dosage of fosinopril (5 mg/kg/d) that was still adequate to reduce their plasma ACE activity and LDL propensity to lipid peroxidation was insufficient to lower their blood pressure." | 1.30 | The angiotensin-converting enzyme inhibitor, fosinopril, and the angiotensin II receptor antagonist, losartan, inhibit LDL oxidation and attenuate atherosclerosis independent of lowering blood pressure in apolipoprotein E deficient mice. ( Attias, J; Breslow, JL; Brodsky, S; Coleman, R; Hayek, T; Keidar, S; Smith, J, 1999) |
| "Cardiac hypertrophy was also observed after chronic inhibition of nitric oxide synthesis." | 1.29 | Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. ( Egashira, K; Kadokami, T; Numaguchi, K; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A, 1995) |
| "Treatment with ramipril reduced blood pressure and force development in response to Bay K8644 in adult SHRSP, although not to levels of WKY rats, whereas WKY rats were unaffected by treatment." | 1.29 | Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats. ( Traub, O; Webb, RC, 1993) |
| "Hydralazine treatment and sodium deprivation did not significantly modify the pressure-independence of renin release by LH rat kidneys." | 1.29 | Pressure control of renal renin release in Lyon hypertensive rats. ( Bertolino, S; Medeiros, IA; Sassard, J; Zhang, BL, 1994) |
| "Hydralazine is an antihypertensive drug that elicits andti-nuclear antibodies in patients as an adverse effect." | 1.29 | Triplex-DNA stabilization by hydralazine and the presence of anti-(triplex DNA) antibodies in patients treated with hydralazine. ( Adams, LE; Hess, EV; Seibold, JR; Thomas, TJ, 1995) |
| "Treatment with captopril also reduced the development of glomerular sclerosis." | 1.29 | Effects of captopril and hydralazine on progression of adriamycin nephropathy in spontaneously hypertensive rats. ( Bogdanovic, G; Djukanovic, L; Jovanovic, D; Kartaljevic, G; Starcevic, A; Susic, D; Varagic, J, 1994) |
| "Treated hypertension is a weak risk factor for acute myocardial infarction in unselected hypertensive patients." | 1.29 | Acute myocardial infarction in patients treated for hypertension in the Skaraborg Hypertension Project. ( Lindblad, U; Ranstam, J; Råstam, L, 1993) |
| "Pyridoxine pretreatment accelerated DA generation from exogenous DOPA and attenuated the DOPA-induced increases in plasma and urinary DOPA and its metabolite 3-O-methyl-DOPA, but accentuated the increase in free DA and its main metabolites, dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), while BP, ANF, cGMP, PRA, and PA remained unaffected." | 1.29 | Defective 3,4-dihydroxyphenylalanine decarboxylation to dopamine in hydralazine-treated hypertensive patients may be pyridoxine remediable. ( Kuchel, O; Shigetomi, S, 1993) |
| "Enalapril treatment significantly reduced proteinuria (731 +/- 23 vs." | 1.29 | Effects of antihypertensive drugs on the progress of renal failure in hyperlipidemic Imai rats. ( Baba, N; Sakemi, T, 1993) |
| "Hydralazine-treated SHRs had a collagen I:III ratio of 10." | 1.29 | Alteration of cardiac collagen phenotypes in hypertensive hypertrophy: role of blood pressure. ( Mukherjee, D; Sen, S, 1993) |
| "3." | 1.29 | Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats. ( Aoki, M; Higaki, J; Moriguchi, A; Morishita, R; Nakamura, Y; Rakugi, H; Tomita, N; Tomita, S; Yamada, K; Yu, H, 1995) |
| "Treatment with hydralazine significantly lowered arterial pressure in SHR and WKY rats, but did not alter the enhanced contraction to phenylephrine or the enhanced relaxation to acetylcholine and nitroprusside in coronary arteris from SHR." | 1.29 | Characterization of endothelium-dependent vasodilation and vasoconstriction in coronary arteries from spontaneously hypertensive rats. ( Fuchs, LC; Johnson, AK; Lamping, KG; Nuno, D, 1996) |
| "Hydralazine was then administered; the effects on regional resistance and blood flow were evaluated with a radionuclide-labeled microsphere technique." | 1.28 | Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes. ( Barnard, JM; Henry, JB; Pedron, SL; Phernetton, TM; Rankin, JH; Reid, DL, 1992) |
| "Treatment with clonidine reduced both circadian variability of BP and HR and the awakening increase." | 1.28 | Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats. ( Janssen, BJ; Struyker-Boudier, HA; Tyssen, CM, 1991) |
| "Captopril was less effective in improving maximal coronary blood flow but was as effective as cilazapril in reducing cardiac hypertrophy." | 1.28 | Effects of two angiotensin converting enzyme inhibitors and hydralazine on coronary circulation in hypertensive rats. ( Clozel, JP; Hess, P; Sprecher, U; Véniant, M, 1991) |
| "Hydralazine treatment, which prevented the development of hypertension, attenuated the increased 3H overflow evoked by PNS in SHR." | 1.28 | Effect of chronically administered hydralazine on altered adrenergic neurotransmission mediated by presynaptic alpha- and beta-adrenoceptors in spontaneously hypertensive rats. ( Kato, H; Mochizuki, S; Takata, Y, 1990) |
| "Hypertension is a frequent complication of a scorpion's sting in children, and specific antihypertensive therapy is indicated in severe cases." | 1.28 | Vasodilators and hypertensive encephalopathy following scorpion envenomation in children. ( Gueron, M; Sofer, S, 1990) |
| "Hydralazine treatment normalized blood pressure in SHR but did not cause regression of cardiac hypertrophy (heart weight to body weight ratio of SHR + hydralazine 4." | 1.28 | Vascular remodeling and improvement of coronary reserve after hydralazine treatment in spontaneously hypertensive rats. ( Anderson, PG; Bishop, SP; Digerness, SB, 1989) |
| "Captopril was also able to reduce the proteinuria of non-diabetic glomerular origin." | 1.28 | Effects of angiotensin converting enzyme inhibitors on the progression of renal failure and proteinuria in humans. ( Alcazar, JM; Gutierrez-Millet, V; Oliet, A; Praga, M; Rodicio, JL; Ruilope, LM, 1989) |
| " In the second protocol, young SHRs (4 weeks of age) were treated with the same dosage of hydralazine until 16 weeks of age." | 1.27 | Independence of blood pressure and locomotor hyperactivity in normotensive and genetically hypertensive rat. ( Atwater, DG; Gellis, JE; Hendley, ED; Low, WC; Whitehorn, D, 1983) |
| "Six women with hypertension are described who developed an immune complex glomerulonephritis after taking 50-300 mg hydralazine daily for 6 months to 7 years." | 1.27 | Hydralazine and lupus nephritis. ( Dowling, JP; Ihle, BU; Kincaid-Smith, P; Whitworth, JA, 1984) |
| " As revealed by the dose-response curves in SHR both drugs produce similar maximal drops in blood pressure by about 54%." | 1.27 | Differential influence of the calcium antagonist nitrendipine and the vasodilator hydralazine on normal and elevated blood pressure. ( Garthoff, B; Knorr, A, 1984) |
| " It is therefore concluded that continuous control of water intake and analysis of the stability of the drug is essential for the establishment of proper dose-response relationships." | 1.27 | Drinking water and drug dosage in rat studies. ( Jakobsen, P; Jespersen, LT; Mikkelsen, EO; Pedersen, OL, 1983) |
| "Diltiazem did not cause tachycardia in either strain." | 1.27 | Hypotensive and diuretic actions of diltiazem in spontaneously hypertensive and Wistar Kyoto rats. ( Nagao, T; Narita, H; Yabana, H; Yamaguchi, I, 1983) |
| "Hydralazine to lower the diastolic blood pressure somewhat, when it was 110 mm Hg or higher, prevented intracranial hemorrhage." | 1.27 | The Parkland Memorial Hospital protocol for treatment of eclampsia: evaluation of 245 cases. ( Cunningham, FG; Pritchard, JA; Pritchard, SA, 1984) |
| " Current recommendations on hydralazine dosage are unsatisfactory for the 40% of hypertensive patients who are rapid acetylators." | 1.27 | Should the acetylator phenotype be determined when prescribing hydralazine for hypertension? ( Freestone, S; Ollerenshaw, JD; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1984) |
| "Hydralazine was discontinued and replaced by placebo during 3 weeks and after this period, verapamil was instituted at increasing doses." | 1.27 | Hypotensive action of verapamil in a group of hydralazine-dependent hypertensive patients. ( Gamio-Capestany, F; García-Barreto, D; González-Gómez, A, 1983) |
| " Responses were assessed by measuring blood pressure and heart rate for 8 hr after dosing and integrating the changes observed over time in order to obtain a mean value." | 1.27 | Baroreflex sensitivity as a determinant of responses to hydralazine in dogs. ( Vidrio, H, 1983) |
| "Hepatitis was severe with hepatic encephalopathy and prolonged prothrombin time." | 1.27 | Dihydralazine hepatitis: report of a case and review of the literature. ( Benhamou, JP; Bernuau, J; Degott, C; Pariente, EA; Pessayre, D, 1983) |
| "Propranolol appears to be a useful antihypertensive drug in the hyperdynamic head-injured patient because it normalizes blood pressure and the underlying hemodynamic abnormalities both by its beta-adrenergic blocking action and by decreasing circulating levels of catecholamines." | 1.27 | Treatment of hypertension associated with head injury. ( Clifton, GL; Grossman, RG; Robertson, CS; Taylor, AA, 1983) |
| "More effective treatment of hypertension is probably a major reason for the 45 percent decrease in stroke mortality rates in the last 12 years alone and for the dramatic decrease in the number of hypertensive patients in whom renal failure or congestive heart failure develops." | 1.27 | Historical perspective on the management of hypertension. ( Moser, M, 1986) |
| "075 mg/kg) of felodipine in combination with the beta-blocker and diuretic." | 1.27 | Felodipine in combination with a beta-blocker and a diuretic in chronic treatment of patients with refractory primary hypertension. ( Andersson, OK; Granérus, G; Hedner, T, 1987) |
| " Labetalol and prazosin also significantly shifted the dose-response curve to the right for phenylephrine but not for angiotensin II." | 1.27 | Analysis of the mechanism underlying the vasodilator action of carvedilol in pithed spontaneously hypertensive rats. ( Akashi, A; Hashimoto, H; Kanda, A; Tanaka, M, 1988) |
| "Hydralazine treatment prevented hypertension in DOCA + HYD but did not prevent development of cardiac hypertrophy (heart weight/body weight of DOCA + HYD 3." | 1.27 | Coronary vascular function and morphology in hydralazine treated DOCA salt rats. ( Anderson, PG; Bishop, SP; Digerness, SB, 1988) |
| "Phentolamine (10(-6) M) pretreatment had no effect on the ouabain-induced contraction but partially suppressed it in both SHR and WKY aortas when diltiazem (10(-5) M) was also added." | 1.27 | Ouabain-induced contraction of vascular smooth muscle in spontaneously hypertensive rats and the effect of hydralazine. ( Iwasaki, T; Kawai, Y; Miyata, S; Morita, S; Nagai, K, 1988) |
| "Hydralazine was given as a subcutaneous pellet (2." | 1.27 | Long-term microvascular response to hydralazine in spontaneously hypertensive rats. ( Dusseau, JW; Hutchins, PM; Lynch, CD; Marshburn, TH; Maultsby, SJ; Smith, TL, 1988) |
| "Streptozotocin diabetes was induced in an M-SHRSP and SHC hybrid (TC), from which diabetic TC was successively bred to the fifth generation." | 1.27 | Establishment and use of the M strain of stroke-prone spontaneously hypertensive rat. ( Chikugo, T; Higashizawa, T; Morita, N; Ohta, Y; Okamoto, K; Suzuki, T; Yamamoto, K, 1986) |
| ") alone or in combination with furosemide (1 mg/kg, i." | 1.27 | The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs. ( Hidaka, H; Sawada, S; Tanioka, Y; Yasuda, Y, 1986) |
| "Captopril also was most effective at changing blood pressure in WKY, while propranolol and hydralazine had similar blood pressure-lowering effects." | 1.27 | Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats. ( Owens, GK, 1987) |
| "Pretreatment with dihydralazine resulted in normalization of distribution coefficients (0." | 1.27 | Interactions of dihydralazine with furosemide in hypertonic patients. ( Biebler, KE; Donner, I; Franke, G; Kairies, M; Siegmund, W, 1987) |
| " Daily oral dosing of hydralazine (2 mg/kg/day) for 14 weeks had little or no effect on SBP, but potentiated the antihypertensive effect of SA446." | 1.27 | [Antihypertensive effects of SA446, hydralazine and the combination on renal hypertensive rats and spontaneously hypertensive rats by long-term treatment]. ( Iso, T; Nakata, K; Nishimura, K; Takada, T; Yamauchi, H, 1986) |
| "Postoperative hypertension is a significant prognostic factor and is associated with an increased incidence of both transient and permanent neurologic deficits." | 1.27 | Control of hypertension following carotid endarterectomy. ( Brown, M; Brown, OW, 1986) |
| "A total of 127 patients with bronchial asthma of infectious-allergic genesis and chronic obstructive bronchitis were examined for the central and regional hemodynamics as well as for the blood levels of serotonin and monoamine oxidase." | 1.27 | [Arterial hypertension in chronic bronchial obstruction and various problems of its treatment]. ( Bobrov, VA; Fushteĭ, IM; Ianushevskaia, TA; Polipova, SN, 1985) |
| "Dihydralazine is a substrate of the human N-acetyltransferase." | 1.27 | The influence of the acetylator phenotype for the clinical use of dihydralazine. ( Biebler, KE; Donner, I; Franke, G; Hüller, H; Kairies, M; Kallwellis, R; Scherber, A; Siegmund, W, 1985) |
| "Hydralazine treatment successfully prevented all these alterations." | 1.27 | Effects of hydralazine on streptozotocin-induced diabetic rats: prevention of hyperlipidemia and improvement in cardiac function. ( Goyal, RK; McNeill, JH; Rodrigues, B, 1986) |
| "Hydralazine was more effective than CGP 18137A in lowering renal and hindquarter resistance." | 1.27 | Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats. ( Smits, JF; Struyker-Boudier, HA, 1985) |
| " Following long term administration of felodipine cardiac output remained elevated owing to an increase in stroke volume." | 1.27 | Haemodynamic effects of short and long term administration of felodipine in spontaneously hypertensive rats. ( Nordlander, M, 1985) |
| "Hydrazine was also detected in the plasma of eight out of 14 hypertensive patients treated chronically with hydralazine (200 mg daily)." | 1.27 | Plasma hydrazine concentrations in man after isoniazid and hydralazine administration. ( Beever, IA; Blair, IA; Brodie, MJ; Clare, RA; Dollery, CT; Mansilla Tinoco, R; Timbrell, JA, 1985) |
| "In order to examine the effect of treatment of mild hypertension of the aged, a 4 year prospective trial was performed in 41 placebo and 38 drug-treated patients with an average age of 76." | 1.27 | The treatment of mild hypertension in the elderly, a prospective study using multiple regression analysis. ( Kuramoto, K; Matsushita, S, 1985) |
| "Captopril was helpful in the management of refractory hypertension in most cases." | 1.26 | Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension. ( Julius, S; Nicholls, MG; Zweifler, AJ, 1981) |
| "Until recently acute renal failure in scleroderma has been uniformly fatal." | 1.26 | Medical treatment of hypertension and renal failure in scleroderma. ( Barnett, AJ, 1981) |
| "Hydralazine treatment did not alter cell-mediated immune responses." | 1.26 | Prospective study of immunologic effects of hydralazine in hypertensive patients. ( Adams, LE; Foad, B; Hess, EV; Litwin, A; Loggie, JH; Zimmer, H, 1981) |
| "Hydralazine treatment did not alter cell-mediated immune responses and hydralazine antibodies were not detected." | 1.26 | Immunologic effects of hydralazine in hypertensive patients. ( Adams, LE; Hess, EV; Litwin, A; Zimmer, H, 1981) |
| "Treatment with clonidine (1 mg/kg, b." | 1.26 | Thermoregulation in spontaneously hypertensive rats: effects of antihypertensive treatments. ( O'Donnell, A; Volicer, L, 1981) |
| " Substantial and prolonged falls in blood pressure were observed following oral dosing with 3 mg/kg of nifedipine in renal hypertensive rats, with 10 mg/kg of nifedipine in normotensive and spontaneously hypertensive rats and with 10 mg/dg of hydralazine in all three groups of animals." | 1.26 | Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats. ( Fujie, K; Kubo, T; Misu, Y; Yamashita, M, 1981) |
| "Hydralazine prevented the increase of arterial pressure and the decrease of stress developed to NA by the aortic strips from both SHR and DOCA/salt rats." | 1.26 | Hydralazine prevents changes in the contractile response of aortic but not portal vein strips in hypertensive rats. ( Pang, CC; Sutter, MC, 1980) |
| "Hydralazine treatment of young SHR partially prevented the increase of both alkaline phosphatase activity and blood pressure that develops with age." | 1.26 | Relationship between blood pressure of spontaneously hypertensive rats and alterations in membrane properties of mesenteric arteries. ( Daniel, EE; Janis, RA; Wei, JW, 1977) |
| "Dihydralazine treatment which lowered blood pressure in young rats from the Lyon Hypertensive Strain (LHS), did not change phenylethanolamine-N-methyltransferase (PNMT) activity, but decreased tyrosine hydroxylase and dopamine-beta-hydroxylase activities in the C2 medullary region." | 1.26 | Dihydralazine and catecholamine-synthesizing enzymes in spontaneous hypertension. ( Denoroy, L; Renaud, B; Sacquet, J; Sassard, J; Vincent, M, 1979) |
| "Pregnancy-related hypertension is not thought to be an absolute contraindication to glucocorticoid therapy for the induction of pulmonary maturity." | 1.26 | Glucocorticoid therapy for the induction of pulmonary maturity in severely hypertensive gravid women. ( Nochimson, DJ; Petrie, RH, 1979) |
| "Treatment with propranolol and hydralazine was effective in controlling her blood pressure and was continued throughout her next two pregnancies, both of which were successful." | 1.26 | Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report. ( Bott-Kanner, G; Joel-Cohen, J; Rosenfeld, JB; Schoenfeld, A; Schweitzer, A, 1978) |
| " Plasma renin concentration and the aortic renin content of the spontaneously hypertensive rat showed divergent changes in response to a blood pressure fall associated with acute diuretic therapy, chronic administration of hydrallazine and in some animals in response to chronic administration of propranolol." | 1.26 | Partial characterization of aortic renin in the spontaneously hypertensive rat and its interrelationship with plasma renin, blood pressure and sodium balance. ( Barrett, JD; Eggena, P; Sambhi, MP, 1978) |
| "The treatment of both hyperlipidemia and hypertension appeared to be more effective than the treatment of hyperlipidemia, alone." | 1.26 | Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta. ( Hollander, W; Kirkpatrick, B; Madoff, I; Paddock, J, 1976) |
| "DOC hypertension was associated with increased 42K turnover (rate constant for DOC = 0." | 1.26 | The effect of norepinephrine on aortic 42K turnover during deoxycorticosterone acetate hypertension and antihypertensive therapy in the rat. ( Jones, AW; Kampschmidt, DL; Sander, PD, 1977) |
| "Three different regimens of drug treatment for hypertension were compared with regard to the development of undesirable side-effects in a group of 53 patients attending a hypertension clinic." | 1.26 | Some side-effects of alpha-methyldopa. ( Pillay, VK, 1976) |
| " Angina and vertebro-basilar insufficiency were each aggravated in one patient, but resolved with dosage adjustment." | 1.25 | Hydrallazine and beta-blockade in refractory hypertension with characterization of acetylator phenotype. ( Hunyor, SN, 1975) |
| " The drugs could be given in a twice-daily dosage and had a much higher degree of patient acceptance." | 1.25 | Oxprenolol and hydrallazine in the treatment of hypertension. ( Freeman, JW; Knight, LW, 1975) |
| "So far as hypertension was controlled under about 210 mmHg, no stroke was observed, while nontreated group developed cerebrovascular lesions spontaneously in about 80 per cent." | 1.25 | Experimental studies on the pathogenesis and prophylaxis of stroke in stroke-prone spontaneously hypertensive rats (SHR). (2) Prophylactic effect of moderate control of blood pressure on stroke. ( Horie, R; Yamori, Y, 1975) |
| "Propranolol was given to 10 hypertensive patients with CGN and hypotensive effect on renal function was observed." | 1.25 | Therapy and prognosis of hypertension in chronic nephritis. ( Kajiwara, N, 1975) |
| "Treatment with alprenolol, a beta-adrenergic blocking agent, did not influence noradrenaline and adrenaline in plasma in the basal state or the urinary excretion of the three catecholamines." | 1.25 | Catecholamines in plasma and urine in patients with essential hypertension determined by double-isotope derivative techniques. ( Christensen, NJ; Pedersen, EB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1125 (75.45) | 18.7374 |
| 1990's | 151 (10.13) | 18.2507 |
| 2000's | 100 (6.71) | 29.6817 |
| 2010's | 85 (5.70) | 24.3611 |
| 2020's | 30 (2.01) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, JJ | 4 |
| Engelhardt, EL | 3 |
| Hirschmann, R | 3 |
| Lundell, GF | 2 |
| Ponticello, GS | 3 |
| Ludden, CT | 3 |
| Sweet, CS | 3 |
| Scriabine, A | 6 |
| Share, NN | 1 |
| Hall, R | 1 |
| Lumma, WC | 1 |
| Raab, AW | 1 |
| Heilman, WP | 1 |
| Heilman, RD | 1 |
| Scozzie, JA | 1 |
| Wayner, RJ | 1 |
| Gullo, JM | 1 |
| Ariyan, ZS | 1 |
| Petersen, HJ | 2 |
| Nielsen, CK | 2 |
| Arrigoni-Martelli, E | 3 |
| Turner, S | 1 |
| Myers, M | 1 |
| Gadie, B | 1 |
| Nelson, AJ | 1 |
| Pape, R | 1 |
| Saville, JF | 1 |
| Doxey, JC | 2 |
| Berridge, TL | 1 |
| Atkinson, JG | 1 |
| Wasson, BK | 1 |
| Kreighbaum, WE | 1 |
| Matier, WL | 1 |
| Dennis, RD | 1 |
| Minielli, JL | 1 |
| Deitchman, D | 1 |
| Perhach, JL | 2 |
| Comer, WT | 1 |
| Chapleo, CB | 1 |
| Myers, PL | 1 |
| Evans, JM | 1 |
| Fake, CS | 1 |
| Hamilton, TC | 2 |
| Poyser, RH | 2 |
| Watts, EA | 1 |
| Bellasio, E | 2 |
| Campi, A | 1 |
| Di Mola, N | 2 |
| Baldoli, E | 2 |
| Bennett, LR | 1 |
| Blankley, CJ | 1 |
| Fleming, RW | 1 |
| Smith, RD | 1 |
| Tessman, DK | 1 |
| Bansal, R | 1 |
| Kumar, D | 1 |
| Carron, R | 1 |
| de la Calle, C | 1 |
| Veldhuizen, GP | 1 |
| Alnazer, RM | 1 |
| de Leeuw, PW | 1 |
| Kroon, AA | 1 |
| Wu, HZ | 1 |
| Cheng, Y | 1 |
| Yu, D | 1 |
| Li, JB | 1 |
| Jiang, YF | 1 |
| Zhu, ZN | 1 |
| Ghazi, L | 1 |
| Li, F | 1 |
| Chen, X | 1 |
| Simonov, M | 1 |
| Yamamoto, Y | 2 |
| Biswas, A | 1 |
| Hanna, J | 1 |
| Shah, T | 1 |
| Peixoto, AJ | 1 |
| Wilson, FP | 1 |
| Ng, Y | 1 |
| Qi, W | 1 |
| King, NKK | 1 |
| Christianson, T | 1 |
| Krishnamoorthy, V | 1 |
| Shah, S | 1 |
| Divani, A | 1 |
| Bettin, M | 1 |
| Coleman, ER | 1 |
| Flaherty, ML | 1 |
| Walsh, KB | 1 |
| Testai, FD | 1 |
| McCauley, JL | 1 |
| Gilkerson, LA | 1 |
| Langefeld, CD | 1 |
| Behymer, TP | 1 |
| Woo, D | 1 |
| James, ML | 1 |
| Inoue, K | 1 |
| Yamada, S | 2 |
| Hoshino, S | 1 |
| Watanabe, M | 1 |
| Kimura, K | 2 |
| Kamijo-Ikemori, A | 1 |
| Muhammad, S | 1 |
| Usman, H | 1 |
| Dawha, YM | 1 |
| Yahya, A | 1 |
| Yekeen, A | 1 |
| Bako, B | 1 |
| Beeston, D | 1 |
| Jepson, R | 1 |
| Cortellini, S | 1 |
| Greene, NH | 1 |
| Pon, FF | 1 |
| Kilpatrick, SJ | 1 |
| Taguchi, R | 1 |
| Shigemi, D | 1 |
| Yasunaga, H | 1 |
| Wautlet, CK | 1 |
| Hoffman, MC | 1 |
| Shahzad Qamar, A | 1 |
| Zamir, A | 1 |
| Khalid, S | 1 |
| Ashraf, W | 1 |
| Imran, I | 1 |
| Hussain, I | 1 |
| Rehman, AU | 1 |
| Saeed, H | 1 |
| Majeed, A | 1 |
| Alqahtani, F | 1 |
| Rasool, MF | 1 |
| Kim, MK | 1 |
| Choe, KR | 1 |
| Jeong, DE | 1 |
| Lee, KN | 1 |
| Cho, I | 1 |
| Kim, HJ | 1 |
| Park, JY | 1 |
| Bhatnagar, M | 1 |
| Agaronov, A | 1 |
| Sarkisyan, E | 1 |
| Sotoudeh Deilamy, I | 1 |
| Pepito, D | 1 |
| Akhondi, H | 1 |
| Kausar, M | 1 |
| Husain, S | 1 |
| Hussain, R | 1 |
| Bhat, AD | 1 |
| Keasler, PM | 1 |
| Kolluru, L | 1 |
| Dombrowski, MM | 1 |
| Palanisamy, A | 1 |
| Singh, PM | 1 |
| Salman, J | 1 |
| Salman, A | 1 |
| Kumar, S | 1 |
| Gjeka, R | 1 |
| Tegeltija, V | 1 |
| Peterson, D | 1 |
| Chams, N | 1 |
| Ross, I | 1 |
| Carrera, JF | 1 |
| Sorace, BJ | 1 |
| Worrall, BB | 1 |
| Southerland, AM | 1 |
| Chiota-McCollum, NA | 1 |
| Antza, C | 1 |
| Dimou, C | 1 |
| Doundoulakis, I | 1 |
| Akrivos, E | 1 |
| Stabouli, S | 1 |
| Haidich, AB | 1 |
| Goulis, DG | 1 |
| Kotsis, V | 1 |
| Kantorowska, A | 1 |
| Heiselman, CJ | 1 |
| Halpern, TA | 1 |
| Akerman, MB | 1 |
| Elsayad, A | 1 |
| Muscat, JC | 1 |
| Sicuranza, GB | 1 |
| Vintzileos, AM | 1 |
| Heo, HJ | 1 |
| Al-Abdouh, A | 1 |
| Siyal, AM | 1 |
| Seid, H | 1 |
| Bekele, A | 1 |
| Garcia, P | 1 |
| Li, Z | 1 |
| Lindner, DP | 1 |
| Bishop, NM | 1 |
| Cipolla, MJ | 1 |
| Doughem, K | 1 |
| Battisha, A | 1 |
| Sheikh, O | 1 |
| Konduru, L | 1 |
| Madoukh, B | 1 |
| Al-Sadawi, M | 1 |
| Shaikh, S | 1 |
| Chera-Aree, P | 1 |
| Tengtrakulcharoen, P | 1 |
| Leetheeragul, J | 1 |
| Sampaojarean, U | 1 |
| Surasereewong, S | 1 |
| Wataganara, T | 1 |
| DiLorenzo, AM | 1 |
| Pasieka, HB | 1 |
| Cardis, MA | 1 |
| Collins, KS | 1 |
| Raviele, ALJ | 1 |
| Elchynski, AL | 1 |
| Woodcock, AM | 1 |
| Zhao, Y | 2 |
| Cooper-DeHoff, RM | 1 |
| Eadon, MT | 1 |
| Yuan, Y | 1 |
| Naito, H | 1 |
| Kitamori, K | 1 |
| Hashimoto, S | 1 |
| Asano, T | 1 |
| Nakajima, T | 2 |
| Cawoski, JR | 1 |
| DeBiasio, KA | 1 |
| Donnachie, SW | 1 |
| Timanus, EA | 1 |
| Zimmerman, DE | 1 |
| Guarascio, AJ | 1 |
| Montepara, CA | 1 |
| Covvey, JR | 1 |
| Nemecek, BD | 1 |
| Matsuyama, T | 1 |
| Ohashi, N | 1 |
| Aoki, T | 1 |
| Ishigaki, S | 1 |
| Isobe, S | 1 |
| Sato, T | 2 |
| Fujikura, T | 1 |
| Kato, A | 1 |
| Miyajima, H | 1 |
| Yasuda, H | 2 |
| Santoriello, D | 1 |
| Bomback, AS | 1 |
| Kudose, S | 1 |
| Batal, I | 1 |
| Stokes, MB | 1 |
| Canetta, PA | 1 |
| Radhakrishnan, J | 1 |
| Appel, GB | 1 |
| D'Agati, VD | 1 |
| Markowitz, GS | 1 |
| Reid, HW | 1 |
| Moorthy, G | 1 |
| Clark, D | 1 |
| Cannon, L | 1 |
| Ming, DY | 1 |
| Bhardwaj, M | 1 |
| Bhardwaj, NJ | 1 |
| Cueto, K | 1 |
| Killeen, TC | 1 |
| Yan, Y | 1 |
| Wang, C | 1 |
| Lu, Y | 1 |
| Gong, H | 1 |
| Wu, Z | 1 |
| Ma, X | 1 |
| Li, H | 1 |
| Wang, B | 1 |
| Zhang, X | 2 |
| Gaynor, MF | 1 |
| Wright, GC | 1 |
| Vondracek, S | 1 |
| Starr, MC | 1 |
| Flynn, JT | 2 |
| Wu, A | 1 |
| Watson, K | 1 |
| Broscious, R | 1 |
| Devabhakthuni, S | 1 |
| Noel, ZR | 1 |
| Sridharan, K | 1 |
| Sequeira, RP | 1 |
| Sharma, M | 1 |
| Foge, M | 1 |
| Mascarenhas, D | 1 |
| Yeboah, KA | 1 |
| Allspaw, A | 1 |
| Al-Makki, A | 1 |
| Shepler, BM | 1 |
| Sogawa, Y | 1 |
| Nagasu, H | 2 |
| Itano, S | 1 |
| Kidokoro, K | 1 |
| Taniguchi, S | 1 |
| Takahashi, M | 1 |
| Kadoya, H | 2 |
| Satoh, M | 2 |
| Sasaki, T | 2 |
| Kashihara, N | 2 |
| Baloch, NU | 1 |
| Ibeabuchi, AN | 1 |
| Kennedy, KN | 1 |
| Wang, YD | 1 |
| Leavitt, K | 1 |
| Običan, S | 1 |
| Yankowitz, J | 1 |
| Pai, AV | 1 |
| West, CA | 1 |
| de Souza, AMA | 1 |
| Kadam, PS | 1 |
| Pollner, EJ | 1 |
| West, DA | 1 |
| Li, J | 3 |
| Ji, H | 1 |
| Wu, X | 1 |
| Zhu, MJ | 1 |
| Baylis, C | 1 |
| Sandberg, K | 1 |
| Kodavanti, UP | 1 |
| Thomas, RF | 1 |
| Ledbetter, AD | 1 |
| Schladweiler, MC | 1 |
| Bass, V | 1 |
| Krantz, QT | 1 |
| King, C | 1 |
| Nyska, A | 1 |
| Richards, JE | 1 |
| Andrews, D | 1 |
| Gilmour, MI | 1 |
| Heijnen, BF | 1 |
| Nelissen, J | 2 |
| van Essen, H | 2 |
| Fazzi, GE | 1 |
| Cohen Tervaert, JW | 1 |
| Peutz-Kootstra, CJ | 1 |
| Mullins, JJ | 2 |
| Schalkwijk, CG | 1 |
| Janssen, BJ | 4 |
| Struijker-Boudier, HA | 1 |
| Sweitzer, NK | 1 |
| Hetzel, SJ | 1 |
| Skalski, J | 1 |
| Velez, M | 1 |
| Eggleston, K | 1 |
| Mitchell, GF | 2 |
| Desai, P | 1 |
| Bholah, MH | 1 |
| Dunn, E | 1 |
| Cao, Y | 1 |
| Mu, JJ | 1 |
| Fang, Y | 1 |
| Yuan, ZY | 1 |
| Liu, FQ | 1 |
| Thandapilly, SJ | 1 |
| Louis, XL | 1 |
| Behbahani, J | 1 |
| Movahed, A | 1 |
| Yu, L | 1 |
| Fandrich, R | 1 |
| Zhang, S | 1 |
| Kardami, E | 1 |
| Anderson, HD | 1 |
| Netticadan, T | 1 |
| Haruna, Y | 1 |
| Ihoriya, C | 1 |
| Yoshida, S | 2 |
| Ishizawa, K | 2 |
| Ayuzawa, N | 1 |
| Ueda, K | 1 |
| Takeuchi, M | 1 |
| Kawarazaki, W | 1 |
| Fujita, T | 3 |
| Nagase, M | 2 |
| Sugama, I | 1 |
| Kohagura, K | 1 |
| Yamazato, M | 1 |
| Nakamura, T | 3 |
| Shinzato, T | 1 |
| Ohya, Y | 1 |
| Tada, Y | 1 |
| Wada, K | 1 |
| Shimada, K | 1 |
| Makino, H | 1 |
| Liang, EI | 1 |
| Murakami, S | 1 |
| Kudo, M | 1 |
| Kitazato, KT | 1 |
| Nagahiro, S | 1 |
| Hashimoto, T | 1 |
| Bakale, RP | 1 |
| Naik, GN | 1 |
| Mangannavar, CV | 1 |
| Muchchandi, IS | 1 |
| Shcherbakov, IN | 1 |
| Frampton, C | 1 |
| Gudasi, KB | 1 |
| Spinasse, LB | 1 |
| Santos, AR | 1 |
| Suffys, PN | 1 |
| Muxfeldt, ES | 1 |
| Salles, GF | 1 |
| Ostrye, J | 1 |
| Hailpern, SM | 1 |
| Jones, J | 1 |
| Egan, B | 1 |
| Chessman, K | 1 |
| Shatat, IF | 1 |
| Suneja, M | 1 |
| Baiswar, S | 1 |
| Vogelgesang, SA | 1 |
| Sharma, A | 1 |
| Colvin-Adams, M | 1 |
| Yancy, CW | 1 |
| Griffin, KA | 1 |
| Polichnowski, A | 1 |
| Litbarg, N | 1 |
| Picken, M | 1 |
| Venkatachalam, MA | 1 |
| Bidani, AK | 1 |
| Gangadhariah, MH | 1 |
| Luther, JM | 1 |
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| Paueksakon, P | 1 |
| Zhang, MZ | 1 |
| Hayward, SW | 1 |
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| Falck, JR | 1 |
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| Imig, JD | 2 |
| Schwartzman, ML | 1 |
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| Capdevila, JH | 1 |
| Pozzi, A | 1 |
| Vadhera, RB | 1 |
| Simon, M | 1 |
| Nagayama, T | 1 |
| Hirooka, Y | 5 |
| Kishi, T | 5 |
| Mukai, Y | 1 |
| Inoue, S | 1 |
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| Takemoto, M | 2 |
| Chishaki, A | 1 |
| Sunagawa, K | 4 |
| Cao, W | 1 |
| Li, A | 1 |
| Wang, L | 1 |
| Zhou, Z | 1 |
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| Bin, W | 1 |
| Wilcox, CS | 2 |
| Hou, FF | 1 |
| Pires, PW | 1 |
| Jackson, WF | 1 |
| Dorrance, AM | 1 |
| de Almeida, PW | 1 |
| Melo, MB | 1 |
| Lima, Rde F | 1 |
| Gavioli, M | 1 |
| Santiago, NM | 1 |
| Greco, L | 1 |
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| Nocchi, E | 1 |
| Parreira, A | 1 |
| Alves, MN | 1 |
| Mitraud, L | 1 |
| Resende, RR | 1 |
| Campagnole-Santos, MJ | 1 |
| Dos Santos, RA | 2 |
| Guatimosim, S | 1 |
| Bradford, MC | 1 |
| Harvey, EM | 1 |
| Batisky, DL | 1 |
| McKay, C | 1 |
| Hall, AB | 1 |
| Cortes, J | 1 |
| Olson-Chen, C | 1 |
| Seligman, NS | 1 |
| Guan, Z | 1 |
| Singletary, ST | 1 |
| Cha, H | 1 |
| Van Beusecum, JP | 1 |
| Cook, AK | 2 |
| Pollock, JS | 2 |
| Pollock, DM | 1 |
| Inscho, EW | 2 |
| Shih, CC | 1 |
| Hii, HP | 1 |
| Tsao, CM | 1 |
| Chen, SJ | 1 |
| Ka, SM | 1 |
| Liao, MH | 1 |
| Wu, CC | 1 |
| Squair, JW | 1 |
| Phillips, AA | 1 |
| Harmon, M | 1 |
| Krassioukov, AV | 1 |
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| Juanola, X | 1 |
| Rodriguez-Moreno, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)[NCT01202864] | 6,000 participants (Actual) | Observational | 2010-08-01 | Completed | |||
| The Effect of Aortic Impedance on Myocardial Relaxation[NCT00204984] | 17 participants (Actual) | Interventional | 2005-05-31 | Completed | |||
| Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886] | 8 participants (Anticipated) | Interventional | 2021-06-08 | Recruiting | |||
| The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388] | 46 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting | |||
| Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923] | 8 participants (Anticipated) | Interventional | 2021-12-31 | Recruiting | |||
| Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093] | 20 participants (Anticipated) | Interventional | 2021-11-29 | Recruiting | |||
| GRAPe Seed Extract and Ventriculovascular Investigation in Normal Ejection-Fraction Heart Failure[NCT01185067] | Phase 1 | 15 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| Cardioprotective Effects of Freeze Dried Grape Powder Supplementation on Blood Pressure and Plasma Lipids/Lipoproteins: A Pilot Study[NCT03659695] | 20 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | |||
| Newer vs Older Antihypertensive Agents in African Hypertensive Patients Trial[NCT01030458] | Phase 4 | 183 participants (Actual) | Interventional | 2010-09-30 | Completed | ||
| African American Study of Kidney Disease and Hypertension ABPM Pilot Study[NCT00582777] | Phase 2/Phase 3 | 180 participants (Anticipated) | Interventional | 2007-11-30 | Completed | ||
| Effect of Potassium Losartan With Bedtime Dosing on Chronic Kidney Disease Patients With Nondipping Blood Pressure Pattern[NCT03603938] | 189 participants (Anticipated) | Interventional | 2018-11-01 | Not yet recruiting | |||
| Prognostic Effect of Isolated Nocturnal Hypertension Pattern With Nondialysis CKD[NCT03604003] | 252 participants (Anticipated) | Interventional | 2018-11-30 | Not yet recruiting | |||
| Acute Effects of High-Intensity Interval Exercise vs. Moderate-Intensity Continuous Exercise on Arterial Stiffness in Chronic Stroke[NCT03570216] | 4 participants (Actual) | Interventional | 2019-03-27 | Completed | |||
| Short - Medium and Long Term Blood Pressure Variability in Essential Hypertensive Patients Treated With Nifedipine GITS or Ramipril - a Randomized Trial[NCT02499822] | Phase 4 | 168 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| Influence of ACE Genotype on Lung Diffusion at Rest and After Fluid Overload in Heart Failure Patients Treated With ACE-inhibitors[NCT00361127] | 100 participants (Actual) | Interventional | 2006-08-31 | Completed | |||
| [NCT00005122] | 0 participants | Observational | 1958-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
This variable gives the proportion of patients reaching blood pressure control over time (< 140 mmHg systolic and < 90 mmHg diastolic) (NCT01030458)
Timeframe: 6 months follow-up after randomization
| Intervention | participants (Number) |
|---|---|
| Amlodipine Plus Valsartan | 58 |
| Hydrochlorothiazide Plus Bisoprolol | 40 |
(NCT01030458)
Timeframe: 6 months follow-up after randomization
| Intervention | participants (Number) |
|---|---|
| Amlodipine Plus Valsartan | 1 |
| Hydrochlorothiazide Plus Bisoprolol | 1 |
Blood pressure is measured by means of validated oscillometric OMRON 705IT recorders (OMRON Healthcare Europe BV, Nieuwegein, Netherlands), after the patient has been seated for 5 minutes in a quiet room, according to the ESC/ESH guidelines. Three consecutive blood pressure readings are obtained and the average of these 3 measurements is used as the primary outcome. (NCT01030458)
Timeframe: 6 months follow-up after randomization
| Intervention | mmHg (Mean) |
|---|---|
| Amlodipine Plus Valsartan | 127.2 |
| Hydrochlorothiazide Plus Bisoprolol | 134.1 |
The time (in weeks) after randomisation that will be required to reach and maintain the target, defined as a blood pressure below 140 mmHg systolic and 90 mmHg diastolic. (NCT01030458)
Timeframe: 6 months follow-up after randomization
| Intervention | weeks (Median) |
|---|---|
| Amlodipine Plus Valsartan | 12 |
| Hydrochlorothiazide Plus Bisoprolol | 18 |
122 reviews available for hydralazine and Blood Pressure, High
| Article | Year |
|---|---|
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypertension, Pr | 2022 |
Hypertensive Crisis in Pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; Nifedipine; Pregnancy | 2022 |
A review on the clinical pharmacokinetics of hydralazine.
Topics: Drug-Related Side Effects and Adverse Reactions; Female; Heart Failure; Humans; Hydralazine; Hyperte | 2022 |
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant | 2023 |
The flipside of hydralazine in pregnancy: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Birth Weight; Female; Heart Rate; Humans; Hydralazine; Hypertension; Hypert | 2020 |
Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review.
Topics: Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Female; Glomerulonephritis; Heart | 2021 |
Genotype-Guided Hydralazine Therapy.
Topics: Antihypertensive Agents; Arylamine N-Acetyltransferase; Dose-Response Relationship, Drug; Drug Resis | 2020 |
Safety and efficacy of intravenous hydralazine and labetalol for the treatment of asymptomatic hypertension in hospitalised patients: A systematic review.
Topics: Administration, Intravenous; Antihypertensive Agents; Humans; Hydralazine; Hypertension; Labetalol | 2021 |
Neonatal hypertension: cases, causes, and clinical approach.
Topics: Administration, Intravenous; Antihypertensive Agents; Birth Weight; Blood Pressure; Blood Pressure D | 2019 |
Heart Failure.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2018 |
Focused Update on Pharmacologic Management of Hypertensive Emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Emergencies; Enalapri | 2018 |
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
A Suspected Case of Hydralazine-Induced Hepatotoxicity: A Case Report and Review of Literature.
Topics: Aged; Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Hyperten | 2018 |
Hydralazine-associated Amenorrhea in a Premenopausal Patient With Chronic Kidney Disease: A Case Report and Review of Literature.
Topics: Adult; Amenorrhea; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Premenopause; | 2018 |
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis | 2019 |
Heart failure in African Americans: disparities can be overcome.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blac | 2014 |
Hypertensive emergencies in pregnancy.
Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten | 2014 |
Hypertensive Emergencies in Pregnancy.
Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E | 2016 |
Perioperative hypertension management.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Enalaprilat; Fenoldopam; Hemodynamics; Humans; | 2008 |
Hydralazine for essential hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Humans; Hydralazine; Hypertension; Vasodilator Agents | 2010 |
Older blood pressure medications-do they still have a place?
Topics: Antihypertensive Agents; Chlorthalidone; Clonidine; Diuretics; Ethacrynic Acid; Guanethidine; Humans | 2011 |
Direct-acting vasodilators.
Topics: Antihypertensive Agents; Hirsutism; Humans; Hydralazine; Hypertension; Minoxidil; Tachycardia; Treat | 2011 |
Hydralazine for essential hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Humans; Hydralazine; Hypertension; Vasodilator Agents | 2011 |
[Clinical efficacy and perinatal outcome of nifedipine for severe preeclampsia: meta-analysis].
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; | 2012 |
Contemporary treatment of heart failure: is there adequate evidence to support a unique strategy for African-Americans? Con position.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blac | 2002 |
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
CURRENT TREATMENT OF HYPERTENSION WITH DRUGS.
Topics: Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Diuretics; Emergencies; Ganglionic | 1963 |
[THERAPY OF ESSENTIAL HYPERTENSION].
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Coronary Disease; Diazoxide; Diet; Dihydr | 1963 |
[ADVANCES IN THE THERAPY OF HYPERTENSIVE DISEASE].
Topics: Antihypertensive Agents; Ganglionic Blockers; Hydralazine; Hypertension; Methyldopa; Mineralocortico | 1963 |
[THE MEDICAMENTOUS TREATMENT OF COMMON ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Benzothiadiazines; Dihydroxyphenylalanine; Ganglionic Blockers; Guanethidin | 1963 |
[THE GROUP OF ANTIHYPERTENSIVE DRUGS].
Topics: Alkaloids; Antihypertensive Agents; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertensio | 1963 |
[DRUG THERAPY OF CIRCULATORY DISEASES].
Topics: Antihypertensive Agents; Arteriosclerosis; Bretylium Compounds; Cardiovascular Diseases; Chlorothiaz | 1964 |
[MALIGNANT HYPERTENSION].
Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricte | 1964 |
[CURRENT FUNDAMENTALS OF TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Cardiovascular System; Diet; Diet Therapy; Diuretics; Ganglionic Blockers; | 1964 |
NEWER DRUGS IN THE TREATMENT OF HYPERTENSION.
Topics: Antihypertensive Agents; Bretylium Compounds; Chlorothiazide; Chlorthalidone; Diuretics; Drug Therap | 1965 |
Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis.
Topics: Antihypertensive Agents; Blood Pressure; Bradycardia; Female; Heart Rate, Fetal; Humans; Hydralazine | 2003 |
[Bases of pharmacological therapy of essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clonidine | 1980 |
The control of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsi | 1981 |
Prazosin: a review of clinical experience in hypertension.
Topics: Adrenergic beta-Antagonists; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Diu | 1981 |
Comparison of labetalol with other anti-hypertensive drugs.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Ethanola | 1982 |
Management of the pregnant patient with chronic hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Humans; Hydralaz | 1983 |
Hypertension in pregnancy. Pathophysiology and management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon | 1984 |
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp | 1984 |
Hypertension--low cost chemotherapy.
Topics: Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1983 |
Calcium, drug action and hypertension.
Topics: Animals; Arteries; Calcium; Chelating Agents; Humans; Hydralazine; Hypertension; Lanthanum; Muscle C | 1983 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazin | 1984 |
[Arterial hypertension in pregnancy. Concise review].
Topics: Cesarean Section; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension; Labor, Induced | 1983 |
The management of hypertension in pregnancy.
Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Drug-induced lupus: clinical and serological studies.
Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cros | 1982 |
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide | 1980 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; H | 1980 |
Hypertensive emergencies: practical approach to treatment.
Topics: Administration, Oral; Antihypertensive Agents; Child; Clonidine; Diazoxide; Emergencies; Female; Hum | 1980 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Brady | 1980 |
Prostaglandins, kinins and the regulation of blood pressure.
Topics: Angiotensins; Blood Pressure; Epoprostenol; Humans; Hydralazine; Hypertension; Kallikreins; Kinins; | 1980 |
Treatment of hypertension in pregnancy.
Topics: Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Placenta; Pre-Eclampsia | 1980 |
[Therapy of essential arterial hypertension. III].
Topics: Antihypertensive Agents; Humans; Hydralazine; Hypertension; Minoxidil; Prazosin; Reserpine; Vasodila | 1980 |
[Arterial hypertension, III. Antihypertensive therapy (1). Diuretics].
Topics: Antihypertensive Agents; Diazoxide; Diuretics; Humans; Hydralazine; Hypertension; Mineralocorticoid | 1980 |
Management of systemic hypertension in children.
Topics: Adolescent; Antihypertensive Agents; Child; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics | 1982 |
Use of nifedipine in the hypertensive diseases of pregnancy.
Topics: Female; Humans; Hydralazine; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Complicat | 1994 |
Management of hypertensive urgencies and emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Emergencies; Enalaprilat; Female; Humans; Hydralazine | 1995 |
Hydralazine-induced constrictive pericarditis.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Autoantibodies; Autoimmune Diseases | 1996 |
[Pregnancy induced hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bed Rest; Contraindications; Fema | 1997 |
Role of tissue angiotensin II in myocardial remodelling induced by mechanical stress.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; | 1999 |
Role of the renin-angiotensin system in cardiac hypertrophy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; | 1999 |
The generalizability of trial data; a comparison of beta-blocker trial participants with a prospective cohort of women taking beta-blockers in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Cohort Studies; Databases as Topic; Diabetes, Gestational; Femal | 2001 |
[Management of high blood pressure using beta-sympatholytics. Review].
Topics: Adrenergic beta-Antagonists; Clonidine; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; | 1976 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo | 1977 |
Pharmacological basis for combination therapy of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; | 1977 |
The use of antihypertensive drugs in hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretic | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 1977 |
Drug-induced systemic lupus erythematosus: a critical review.
Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen | 1975 |
Drug treatment of hypertension.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agent | 1975 |
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru | 1977 |
Drug therapy reviews. Pharmacology and clinical use of drugs in hypertensive emergencies.
Topics: Adult; Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Nitroprus | 1977 |
Pharmacology and clinical use of drugs in hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Aorta; Brain Diseases; Cerebral Hemorrhage; Diazox | 1977 |
Preventing, detecting and managing adverse reactions of antihypertensive agents in the ambulant patient with essential hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Ethacrynic Acid | 1977 |
Physiologic and biochemical profile of hypertension for rational clinical management.
Topics: Adrenal Gland Diseases; Angiotensins; Body Fluid Compartments; Chlorthalidone; Diuretics; Guanethidi | 1978 |
Hydralazine therapy for hypertension during the anesthetic and postanesthetic periods.
Topics: Anesthesia; Humans; Hydralazine; Hypertension; Postoperative Care; Surgical Procedures, Operative; T | 1978 |
Drug therapy. Hydralazine.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Blood Pressure; Cardiac Output; Chronic Disease; Dru | 1976 |
How to manage hypertensive emergencies and urgencies.
Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxid | 1976 |
Drug-induced changes in mechanics and structure of cerebral arterioles.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Brain; Chronic Disease; Compliance; H | 1992 |
Reactive hypoglycemic coma due to insulin autoimmune syndrome: case report and literature review.
Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Blood Glucose; Child, Preschool; Coma; Diagnosi | 1992 |
Fatal hepatotoxicity induced by hydralazine or labetalol.
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Hypertension; Labetalol; Male | 1991 |
Management of hypertensive emergencies: changing therapeutic options.
Topics: Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Nicardipine; Nitroprusside | 1991 |
Cardiac remodeling in hypertension and following myocardial infarction: effects of arteriolar vasodilators.
Topics: Animals; Arterioles; Cardiomegaly; Extracellular Matrix; Humans; Hydralazine; Hypertension; Myocardi | 1991 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Clonidine; Diuretics; Female; Humans; Hydrala | 1985 |
Hypertension in pregnant women.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Delivery, Obstetric; Diazoxide; Emergencies; F | 1985 |
Vasodilators in hypertension--a review with special emphasis on the combined use of vasodilators and beta-adrenoceptor blockers.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 1985 |
Antihypertensive drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H | 1985 |
The evolution of antihypertensive therapy.
Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers; | 1985 |
Treatment of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Human | 1986 |
Effects of antihypertensive treatment on cerebral perfusion.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc | 1987 |
Hypertensive emergencies and urgencies.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 1986 |
Vasodilator drugs in the treatment of hypertension.
Topics: Calcium Channel Blockers; Captopril; Cardiac Output; Diazoxide; Diuretics; Dose-Response Relationshi | 1985 |
[Treatment of the hypertensive crisis].
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Diaz | 1973 |
[Use of beta-receptor blocking agents in the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Cardiac Output; Depression, Chemical; Diuretics; Humans | 1973 |
Combination antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamine; Antidepressive Agents; Antih | 1971 |
The clinical pharmacology of commonly used antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Autonomic Fibers | 1974 |
Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies.
Topics: Antihypertensive Agents; Bethanechol Compounds; Clonidine; Diazoxide; Diuretics; Emergencies; Ferric | 1974 |
The mechanisms of action of some antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Brain; Bretylium Compounds; Clonidine; Debrisoquin; Diuretics; Gua | 1973 |
The treatment of chronic hypertension.
Topics: Adult; Blood Pressure Determination; Chronic Disease; Diuretics; Female; Ganglionic Blockers; Guanet | 1971 |
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block | 1971 |
The chemotherapy of hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydra | 1971 |
[Cardiac complications in hypertension].
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Diseas | 1972 |
The treatment of hypertension. Why, when and how.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyd | 1972 |
[Drug therapy of arterial hypertension].
Topics: Antihypertensive Agents; Arteries; Cardiac Output; Clonidine; Diuretics; Drug Combinations; Guanethi | 1972 |
Medical management of primary hypertension. 2.
Topics: Blood Pressure; Cardiac Output; Diuretics; Heart Rate; Humans; Hydralazine; Hypertension; Methyldopa | 1972 |
Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis.
Topics: Acetylation; Adult; Antibodies, Antinuclear; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Bloo | 1973 |
[Selection of antihypertensive drugs].
Topics: Antihypertensive Agents; Benzyl Compounds; Diazoxide; Drug Therapy, Combination; Guanethidine; Guani | 1973 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Coronary D | 1974 |
Vasodilator drugs in the treatment of hypertension.
Topics: Administration, Oral; Cardiac Output; Diazoxide; Diuretics; Dose-Response Relationship, Drug; Drug S | 1974 |
Hypertensive emergencies.
Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume | 1974 |
Individualization of antihypertensive drug therapy.
Topics: Blood Volume; Cardiac Output; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Intestinal | 1974 |
The physiologic and pharmacologic basis for the clinical treatment of hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Emergencies; Guanethidine; Humans; Hydralazine; Hyperten | 1967 |
Recent advances in the medical and surgical treatment of hypertension.
Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni | 1968 |
Hypertension in children and adolescents. II. Drug therapy.
Topics: Age Factors; Antihypertensive Agents; Blood Pressure Determination; Child; Chlorothiazide; Chronic D | 1969 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Diazoxide; Emergencies; Humans; Hyd | 1969 |
[Chemotherapy of hypertension].
Topics: Benzothiadiazines; Blood Pressure; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Mono | 1969 |
[Side effects of antihypertensive therapy].
Topics: Acetazolamide; Antihypertensive Agents; Blood Pressure; Furosemide; Humans; Hydralazine; Hydrochloro | 1970 |
[Treatment of hypertension. 2].
Topics: Antihypertensive Agents; Humans; Hydralazine; Hypertension | 1965 |
180 trials available for hydralazine and Blood Pressure, High
| Article | Year |
|---|---|
Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage.
Topics: Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Humans; Hydralazine; Hypertension; Lab | 2022 |
Comparison of intravenous labetalol and hydralazine for severe hypertension in pregnancy in Northeastern Nigeria: A randomized controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant; Infant, | 2022 |
Left ventricular responses to acute changes in late systolic pressure augmentation in older adults.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Disease Progression; Dose-Respons | 2013 |
Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial.
Topics: Acute Disease; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; | 2011 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black Peop | 2011 |
Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; H | 2011 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood P | 2013 |
Phosphodiesterase type 5 inhibition improves arterial stiffness after exercise but not exercise capacity in hypertensive men.
Topics: Adult; Blood Pressure; Exercise; Exercise Tolerance; Humans; Hydralazine; Hypertension; Male; Middle | 2013 |
Endogenous endothelin-1 limits exercise-induced vasodilation in hypertensive humans.
Topics: Adult; Antihypertensive Agents; Cross-Over Studies; Endothelin Receptor Antagonists; Endothelin-1; F | 2002 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal | 2007 |
Efficacy and safety comparison of nitrendipine and hydralazine as antihypertensive monotherapy.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method | 1984 |
Endralazine, a new peripheral vasodilator: absence of effect of acetylator status on antihypertensive effect.
Topics: Acetylation; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combin | 1983 |
[Therapeutic equivalent of a single and divided daily dose of 2 Tri-Torrat coated tablets].
Topics: Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Combinations; Female; Humans; Hyd | 1984 |
Veterans Administration cooperative study on nadolol as monotherapy and in combination with a diuretic.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bendroflumethiazide; Clinical Trials as Topic; Diure | 1984 |
Beta-adrenoceptor blockade and vasodilatation in essential hypertension. Hemodynamic studies at rest and during exposure to stress.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Clinical Trials as Topic; Drug The | 1984 |
An appraisal of antihypertensive efficacy and adverse reactions with two drug regimens: enalapril maleate as part of triple therapy compared to conventional triple therapy in moderate to severe hypertension.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Dipeptides; Drug Therapy, Combination; Ena | 1984 |
Guanfacine alone and in combination therapy in the treatment of moderate and severe hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Therapy, Combi | 1983 |
Propranolol-hydralazine combination in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blin | 1983 |
[Treatment of refractory hypertension with a fixed oxprenolol/chlorthalidone/hydralazine combination. Results of an open multicenter trial].
Topics: Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydralazine; Hypertensi | 1983 |
Hydralazine and prazosin in the treatment of hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate | 1983 |
[Treatment of hypertensive patients with adelphan-esidrex].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Combinations; F | 1983 |
Efficacy of nadolol alone and combined with bendroflumethiazide and hydralazine for systemic hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; | 1983 |
Evaluation of once daily hydralazine in inadequately controlled hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Female; Half-Life; Heart Rate; Hum | 1983 |
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; | 1983 |
The management of hypertension in pregnancy.
Topics: Cerebrovascular Circulation; Clinical Trials as Topic; Diazoxide; Diuretics; Female; Humans; Hydrala | 1984 |
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Cli | 1984 |
Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Chromatography, High Pressure Liquid; Dopamine; Drug Evaluation; Epinep | 1984 |
Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients.
Topics: Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Outpa | 1984 |
Comparison of the antihypertensive activity of cadralazine (ISF 2469) and dihydralazine during chronic treatment.
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Dihydralazine; Female; Headache; Heart Rat | 1983 |
Treatment of acute pregnancy-related hypertension: labetalol and hydralazine compared.
Topics: Ethanolamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Pregnancy; Pregnanc | 1983 |
A comparison of minoxidil and hydralazine in non-azotemic hypertensives.
Topics: Adult; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mid | 1983 |
[Methodologic approach to individual evaluation of the pharmacodynamic effects of single doses of hydralazine, endralazine, prazosine and propranolol in hypertension patients].
Topics: Adult; Antihypertensive Agents; Cardiac Output; Cardiography, Impedance; Humans; Hydralazine; Hypert | 1984 |
[Long-term experiences with an antihypertensive combination].
Topics: Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydralazine; Hypertensi | 1982 |
Double-blind comparison of dihydralazine and prazosin in hypertensive patients on the diuretic-reserpine regimen.
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Female; Humans; Hydralazi | 1981 |
[Combination therapy of hypertension. Results of a study with Docidrazin].
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hy | 1982 |
Peripheral vasodilatation in the treatment of hypertension. Prazosin compared with hydralazine in patients not responding to beta-receptor blockade.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Drug Therapy, Combinati | 1982 |
Hydralazine once daily in hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; D | 1982 |
Comparison of labetalol, hydrallazine, and propranolol in the therapy of moderate hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; | 1980 |
[Cross-over trial with Peripress (prazosin) and Apresolin (hydralazin), both in combination with beta-blocker].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Cross-Sectional Studies; Drug Evaluation; Dru | 1980 |
Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension.
Topics: Acebutolol; Adult; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Ethanolamines | 1980 |
Hydralazine and oxprenolol in the treatment of hypertension and the effect of these drugs on plasma renin activity.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Huma | 1980 |
[Hydralazine in arterial hypertension. Randomized, double-blind comparison between conventional and slow-release preparations].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Hum | 1980 |
[Use of oxprenolol, triamterene, and dihydralazine in the treatment of essential hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hyd | 1980 |
Clinical evaluation of the antihypertensive effect of metoprolol in combination with hydrochlorothiazide and hydralazine in an unselected hypertensive population.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cholesterol; Clinical Trials as Topic; Drug Therapy, | 1980 |
The prevention of hypertension at intubation. A controlled study of intravenous hydrallazine on patients undergoing intracranial surgery.
Topics: Adult; Anesthesia, General; Brain; Clinical Trials as Topic; Female; Humans; Hydralazine; Hypertensi | 1981 |
Antihypertensive action of drug combination: Timolol, hydralazine, hydrochlorothiazide and triamterene.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydralazine | 1981 |
Comparison of prazosin with hydralazine in patients receiving hydrochlorothiazide. A randomized, double-blind clinical trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blin | 1981 |
[Current state of the treatment of arterial hypertension].
Topics: Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Heart Failure; Humans; Hydralazine | 1980 |
Comparative study of oxdralazine and dihydralazine in essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Ethanolamin | 1981 |
Effect of antihypertensive drugs on plasma renin activity and urinary excretion of prostaglandin E2.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dinoprostone; Female; Humans; Hydralazine; | 1981 |
Comparison of labetalol, propranolol and hydralazine in hypertensive out-patients.
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazi | 1982 |
A trial of metoprolol in hypertensive insulin-dependent diabetic patients.
Topics: Adult; Aged; Benzothiadiazines; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; | 1982 |
Single versus multiple daily administration of hydralazine in the maintenance treatment of hypertension. Clinical and pharmacokinetic aspects.
Topics: Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Heart Rate; Humans; Hydralazi | 1982 |
[A cross-over comparison of dihydralazine and minoxidil in severe hypertension (author's transl)].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Humans; Hydralazine; Hypertens | 1982 |
[Treatment of hypertension with a drug combination, consisting of bemetizide, triamterene, dihydralazine and bupranolol (author's transl)].
Topics: Adult; Benzothiadiazines; Bupranolol; Dihydralazine; Drug Combinations; Humans; Hydralazine; Hyperte | 1982 |
The effects of prophylactic management and therapeutics on hypertensive disease in pregnancy: preliminary studies.
Topics: Adult; Antihypertensive Agents; Birth Weight; Blood Pressure; Body Weight; Female; Humans; Hydralazi | 1981 |
Once daily slow-release hydralazine in hypertension.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Oxpren | 1981 |
Are prostaglandins involved in the antihypertensive effect of dihydralazine?
Topics: Adult; Diclofenac; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertensi | 1981 |
Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Creatinine; Ethanolamines; Female; Fetus; Humans; Hydralazine; Hypertension; | 1980 |
Hydralazine in arterial hypertension. Randomized double-blind comparison of conventional/Slow-Release formulation and of b.i.d./q.i.d. dosage regimens.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Administration S | 1980 |
Double-blind cross-over comparison of hydralazine and prazosin in hypertensive subjects on a beta-adrenoceptor blocking agent (atenolol).
Topics: Atenolol; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Prazosi | 1980 |
Emergency treatment of severe hypertension evaluated in a randomized study. Effect of rest and furosemide and a randomized evaluation of chlorpromazine, dihydralazine and diazoxide. Danish Multicenter Study.
Topics: Adult; Aged; Chlorpromazine; Denmark; Diazoxide; Dihydralazine; Drug Administration Schedule; Female | 1980 |
Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Drug Therapy, Co | 1995 |
Effects of hydralazine on placental and renal circulation in pre-eclampsia.
Topics: Adult; Birth Weight; Blood Circulation; Blood Flow Velocity; Blood Pressure; Drug Evaluation; Female | 1995 |
Beta-adrenergic blocking agents in the treatment of pregnancy-induced hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Female | 1995 |
Factors affecting lipoprotein lipase in hypertensive patients.
Topics: Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Insulin; Lipid | 1995 |
Comparison of captopril, hydralazine and nifedipine as third drug in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Benzothiadiazines; Captopril; Diuretics; Drug Therapy, Combinati | 1993 |
Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice.
Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydra | 1996 |
Effects of lisinopril vs hydralazine on left ventricular hypertrophy and ambulatory blood pressure monitoring in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitor | 1995 |
Improvement of alveolar-capillary membrane diffusing capacity with enalapril in chronic heart failure and counteracting effect of aspirin.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood-Air Barrier; Bradykinin; Cyclooxygena | 1997 |
Vasodilator therapy of hypertensive acute left ventricular failure: comparison of captopril-prazosin with hydralazine-isosorbide dinitrate.
Topics: Adult; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Humans; Hydralazine; H | 1998 |
Fosinopril improves left ventricular diastolic function in young mildly hypertensive patients without hypertrophy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Data Interpretation, Statistical; Dose-Response Rela | 2002 |
[Initial treatment of essential hypertension. Combination of a thiazide with methyldopa, and a beta-blocking agent with hydralazine].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clinical Trial | 1978 |
Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials a | 1979 |
Double-blind comparison of minoxidil and hydrallazine in severe hypertension.
Topics: Adult; Aged; Cardiomegaly; Creatinine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; | 1976 |
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Dru | 1977 |
[An example of an acceptable combination in the treatment of arterial hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Combinations; Drug E | 1978 |
Vasodilators in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzothiadiazines; Clinical Trials as T | 1975 |
Changing concepts in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Animals; Benzothiadiazines; Clinical Trials as Topic; Clonidine; | 1975 |
Hydrallazine with beta-blocker and diuretic in the treatment of hypertension. A double-blind crossover study.
Topics: Adult; Aged; Cyclopenthiazide; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; | 1979 |
[2 antihypertensive therapeutic regimes compared in a controlled clinical trial in general practice. Cyclopenthiazide + KC1/methyldopa versus oxprenolol/hydralazine].
Topics: Adult; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Drug Evaluation; Drug Therapy, Combina | 1977 |
Propranolol in the treatment of essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combinati | 1977 |
Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension.
Topics: Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Femal | 1977 |
Studies with prazosin--a new effective hypotensive agent. II. Two double-blind cross-over studies comparing the effects of prazosin and hydrallazine.
Topics: Adult; Chlorothiazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fem | 1977 |
Controlled clinical study on antihypertensive treatment with a diuretic and methyldopa compared with a beta-blocking agent and hydralazine.
Topics: Blood Pressure; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Double-Blind Method; Drug Eva | 1977 |
Combination hypotensive therapy with atenolol, bendrofluazide and hydrallazine.
Topics: Angiotensin II; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blin | 1977 |
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular | 1978 |
Effect of timolol plus hydrochlorothiazide plus hydralazine on essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hydr | 1978 |
Labetalol compared with prindolol plus hydraliazine in the treatment of hypertension: a double-blind cross-over study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Fema | 1978 |
Effect of clonidine on sympathetic nervous activity in hydralazine-treated hypertensive patients.
Topics: Adult; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1978 |
[Effect of apressin and its combination with obzidan on central hemodynamic indices in the treatment of hypertension].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diastole; Drug Evaluation; Drug Therapy, Combinatio | 1978 |
The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Electrolytes; Female; H | 1978 |
Studies with prazosin--a new effective hypotensive agent. III. An acute double-blind cross-over study comparing the effects of single doses of prazosin and hydrallazine in combination with propranolol and a diuretic.
Topics: Adult; Aged; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Me | 1978 |
Nepresol in the treatment of hypertension of major severity.
Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Therapy, Comb | 1979 |
Sympathetic reflex responses during treatment of essential hypertension with hydrallazine and oxprenolol.
Topics: Blood Pressure; Humans; Hydralazine; Hypertension; Norepinephrine; Oxprenolol; Posture; Reflex; Reni | 1979 |
Hydralazine slow-release: observations on serum profile and clinical efficacy in man.
Topics: Adult; Alprenolol; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Hydralazin | 1977 |
Antihypertensive effect and plasma levels of labetalol. A comparison with propranolol and dihydrallazine.
Topics: Adult; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hydralaz | 1979 |
Treatment of hypertension successively with a diuretic, clonidine or a beta-blocking agent and hydralazine.
Topics: Benzothiadiazines; Clonidine; Cyclic S-Oxides; Diuretics; Drug Therapy, Combination; Heart Rate; Hum | 1977 |
[Long-term treatment of essential hypertension with hydralazine and alprenolol].
Topics: Alprenolol; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; M | 1978 |
Effect of propranolol on sympathetic nervous activity in hydrallazine-treated hypertensive patients.
Topics: Adult; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Male; | 1978 |
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydroch | 1978 |
[Experience with the combination of beta receptor blockader and hydralazine in the treatment of hypertension].
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Headache; Human | 1976 |
Combination therapy of essential hypertension with pindolol (Visken) and hydralazine.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therap | 1975 |
Hydrallazine or phentolamine as adjuncts to beta-adrenoceptor blockade/thiazide therapy in hypertension.
Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Therapy, Combin | 1976 |
Treatment of severe and moderate hypertension with minoxidil: experience in twenty-eight patients.
Topics: Adult; Clinical Trials as Topic; Edema; Female; Humans; Hydralazine; Hypertension; Hypertrichosis; M | 1976 |
A cross-over study between hydrallazine and prazosin.
Topics: Clinical Trials as Topic; Humans; Hydralazine; Hypertension; Prazosin; Propranolol; Quinazolines | 1976 |
Combination therapy of essential hypertension with pindolol (Visken) and hydralazine.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydr | 1976 |
Some haemodynamic effects of compound AH 5158 compared with propranolol, propranolol plus hydrallazine, and diazoxide: the use of AH 5158 in the treatment of hypertension.
Topics: Blood Pressure; Cardiac Output; Clinical Trials as Topic; Diazoxide; Drug Therapy, Combination; Etha | 1975 |
Comparison of multiple and combination tablet drug therapy in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug C | 1975 |
Treatment of hypertension by computer and physician-a prospective controlled study.
Topics: Benzothiadiazines; Computers; Diuretics; Drug Therapy, Combination; Female; Guanethidine; Humans; Hy | 1977 |
A comparative study of the hemodynamic effects of single intravenous doses of 3-hydrazino-6-[N,N-bis-(2-hydroxyethyl)-amino]-pyridazine-dihydrochloride and hydralazine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Coronary Circulation; Electrocardiog | 1976 |
Vasodilating drugs: contrasting haemodynamic effects.
Topics: Diazoxide; Hemodynamics; Humans; Hydralazine; Hypertension; Minoxidil; Nitroprusside; Vasodilator Ag | 1976 |
Prazosin and hydrallazine in the treatment of hypertension.
Topics: Heart Rate; Humans; Hydralazine; Hypertension; Prazosin; Quinazolines; Time Factors | 1976 |
Partial versus complete control of blood pressure in the prevention of hypertensive complications.
Topics: Atrial Fibrillation; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-Up St | 1975 |
Antihypertensive effect of a dopamine beta hydroxylase inhibitor, bupicomide: a comparison with hydralazine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dopamine beta-Hydroxylase; | 1975 |
Duration of hydralazine action in hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydralazine; Hypertensi | 1975 |
Letter: Prazosin in treatment of hypertension.
Topics: Humans; Hydralazine; Hypertension; Male; Piperazines; Propranolol; Quinazolines | 1975 |
Antihypertensive drug effects on placental flow velocity waveforms in pregnant women with severe hypertension.
Topics: Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Nifed | 1992 |
Non-invasive determination of arterial diameter and distensibility by echo-tracking techniques in hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Atenolol; Blood Pressure; Captop | 1992 |
Effect of food on oral availability of apresoline and controlled release hydralazine in hypertensive patients.
Topics: Administration, Oral; Adult; Biological Availability; Delayed-Action Preparations; Double-Blind Meth | 1990 |
Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Diuretics; Double-Blind Me | 1990 |
Early blood pressure control improves pregnancy outcome in primigravid women with mild hypertension.
Topics: Adult; Birth Weight; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; D | 1991 |
Maternal and fetal haemodynamics in hypertensive pregnancies during maternal treatment with intravenous hydralazine or labetalol.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Heart Rate, Fetal; Hemodynamics; Hum | 1991 |
Hydralazine does not stimulate prostacyclin biosynthesis in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Drug Interactions; Epoprostenol; Female; Humans; Hydralazine; Hypertens | 1990 |
A randomized comparison of early with conservative use of antihypertensive drugs in the management of pregnancy-induced hypertension.
Topics: Adult; Birth Weight; Cesarean Section; Dihydralazine; Double-Blind Method; Drug Therapy, Combination | 1990 |
Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study.
Topics: Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; | 1990 |
Hydralazine dose-response curve analysis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method | 1990 |
Influence of converting enzyme inhibition on glomerular filtration rate and proteinuria.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Female; Furos | 1990 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Doub | 1988 |
[Multicenter study of atenolol, combined with hydralazine and bendroflumethiazide in the treatment of essential, mild, and severe, arterial hypertension].
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Drug Therapy, Combination; Female; Humans; Hydralazine; | 1989 |
Pseudo renal artery stenosis (PRAS) syndrome.
Topics: Angiography; Blood Pressure; Body Weight; Creatinine; Double-Blind Method; Enalapril; Humans; Hydral | 1989 |
Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension.
Topics: Aged; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Postope | 1989 |
The natural history of medication compliance in a drug trial: limitations of pill counts.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Female; Guanidines; Humans; Hydralazine; Hyperten | 1989 |
Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension.
Topics: Blood Pressure; Fees, Pharmaceutical; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; | 1989 |
Acute hemodynamic effects of pinacidil and hydralazine in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Double-Blind Method; Drug Evalua | 1985 |
Nifedipine tablet vs. hydralazine in patients with persisting hypertension who receive combined diuretic and beta-blocker therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Blood Pressure | 1986 |
Comparative study of endralazine and hydralazine for the treatment of hypertension uncontrolled by a beta-blocker and diuretic.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antibodies, Antinuclear; Diuretics; Double-Blind Method; D | 1986 |
Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Felodipine; Female; Humans; Hydralazine; | 1986 |
[Double-blind comparison of fixed combination preparations of a beta blocker and a diuretic and beta blocker, a diuretic and hydralazine in patients with coronary heart disease and arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Clinical Trials as Topic; Coronary Disease; Double-Bli | 1986 |
Systemic and renal hemodynamic effects of single oral doses of cadralazine and long term antihypertensive effects of cadralazine in patients receiving therapy with beta-blockers and diuretics.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Antihypertensive Agents; Diuretics; Double-Blind | 1986 |
Clinical evaluation of felodipine in hypertensive patients previously treated with a triple drug regimen.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Humans; | 1987 |
Vasodilators and regression of left ventricular hypertrophy. Hydralazine versus prazosin in hypertensive humans.
Topics: Adult; Cardiomegaly; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prazosin; Vasodil | 1987 |
Long term haemodynamic effects of pinacidil and hydralazine in arterial hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Glomerular Filtration Rate; Guani | 1988 |
Double-blind comparator trials with pinacidil, a potassium channel opener.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Guanidines; | 1988 |
A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; H | 1987 |
Comparative efficacy and safety of immediate-release and controlled-release hydralazine in black hypertensive patients.
Topics: Adult; Aged; Black People; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Do | 1987 |
The use of felodipine in the treatment of severe hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardi | 1987 |
Comparison of antihypertensive, renal hemodynamic, and humoral effects of pinacidil and hydralazine monotherapy.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-B | 1987 |
The systolic hypertension in the elderly pilot program: methodological issues.
Topics: Age Factors; Aged; Aged, 80 and over; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Doub | 1988 |
[Endralazine monotherapy in comparison with prazosin and hydralazine in arterial hypertension].
Topics: Adult; Clinical Trials as Topic; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prazosin; Pyr | 1986 |
Comparison of labetalol and dihydralazine in hypertensive emergencies of pregnancy.
Topics: Blood Pressure; Clinical Trials as Topic; Dihydralazine; Female; Heart Rate; Heart Rate, Fetal; Huma | 1987 |
Verapamil in essential hypertension: a comparison with atenolol plus hydralazine.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Echocardiogra | 1987 |
Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Drug Administration Schedule; Drug Thera | 1987 |
Treatment of hypertension during pregnancy with hydralazine monotherapy or with combined therapy with hydralazine and pindolol.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pindolo | 1986 |
Antihypertensive efficacy of pinacidil--automatic ambulatory blood pressure monitoring.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Female; Guanidines; Heart Rat | 1986 |
A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy.
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fetus; Gestational Age; Humans; | 1985 |
Antihypertensive treatment in pregnancy: analysis of different responses to oxprenolol and methyldopa.
Topics: Adult; Birth Weight; Clinical Trials as Topic; Female; Humans; Hydralazine; Hypertension; Infant, Ne | 1985 |
Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: hemodynamic and neuroendocrine mechanisms of action.
Topics: Adult; Drug Therapy, Combination; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; Hydrochl | 1985 |
Hydralazine and beta-adrenergic blockade in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combinat | 1974 |
Effect of treatment on morbidity in hypertension. Veterans Administration Cooperative Study on Antihypertensive Agents. Effect on the electrocardiogram.
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Clinical Trials as Topi | 1973 |
[Ambulant long-term treatment of arterial hypertension].
Topics: Animals; Antihypertensive Agents; Chlorothiazide; Clinical Trials as Topic; Diuretics; Female; Gangl | 1965 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascu | 1972 |
One-tablet combination drug therapy in the treatment of hypertension.
Topics: Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Dosage Forms; Drug Com | 1972 |
[Clinical administration of hydralazin (Depressan) in essential and renal hypertension].
Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Humans; Hydralazine; Hypert | 1972 |
[Combination therapy with alprenolol and hydralazine in essential hypertension. A controlled clinical study].
Topics: Adult; Alprenolol; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Drug Therapy, Com | 1973 |
Treatment of hypertension with large doses of the beta-adrenergic blocking drug oxprenolol, alone, and in combination with the vasodilator dihydralazine.
Topics: Chlorothiazide; Clinical Trials as Topic; Drug Synergism; Furosemide; Heart Rate; Hydralazine; Hyper | 1973 |
A long-term study of the antihypertensive effect of alprenolol.
Topics: Adult; Aged; Alprenolol; Blood Pressure Determination; Chlorthalidone; Clinical Trials as Topic; Del | 1974 |
The effect of alprenolol in combination with hydralazine in essential hypertension. A double-blind, crossover study and a long-term follow-up study.
Topics: Adult; Alprenolol; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Delayed-A | 1974 |
Alprenolol in hypertension.
Topics: Aged; Alprenolol; Benzothiadiazines; Chlorthalidone; Clinical Trials as Topic; Digitalis; Diuretics; | 1974 |
Appraisal of antihypertensive drug therapy.
Topics: Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Diabetes Comp | 1974 |
Partial reduction of blood pressure and prevention of complications in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-U | 1974 |
The Australian National Blood Pressure Study.
Topics: Adult; Aged; Antihypertensive Agents; Australia; Chlorothiazide; Clinical Trials as Topic; Clonidine | 1974 |
Hypertension: a challenge in preventive medicine.
Topics: Age Factors; Attitude to Health; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disea | 1974 |
Letter: Prazosin and hydrallazine in the treatment of hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Furans; Humans; Hydralazine; Hypertension; Pipera | 1974 |
Reserpine, hydralazine, hydrochlorothiazide combination (Ser-AP-ES) in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Computers; Drug Combinations; Humans; Hydrala | 1972 |
Hydralazine and methyldopa in thiazide-treated hypertensive patients.
Topics: Black People; Clinical Trials as Topic; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertensi | 1970 |
Combined dihydralazine and propranolol in the treatment of hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Guanidines; Humans; Hydralazine; Hype | 1970 |
Effect of treatment on morbidity and mortality in hypertension.
Topics: Age Factors; Black or African American; Blood Pressure; Humans; Hydralazine; Hydrochlorothiazide; Hy | 1971 |
[Medical treatment of arterial hypertension].
Topics: Antihypertensive Agents; Diuretics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mi | 1971 |
1192 other studies available for hydralazine and Blood Pressure, High
| Article | Year |
|---|---|
beta-Adrenergic blocking agents with acute antihypertensive activity.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Animals; Antihypertensive Agents; Blood Pressure; Do | 1979 |
Symbiotic approach to drug design: antihypertensive beta-adrenergic blocking agents.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Chemistry, Pharmaceutical; Dogs; Hype | 1979 |
Synthesis and antihypertensive activity of novel 3-hydrazino-5-phenyl-1,2,4-triazines.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hype | 1979 |
Synthesis and hypotensive activity of N-alkyl-N"-cyano-N'-pyridylguanidines.
Topics: Animals; Antihypertensive Agents; Dogs; Female; Guanidines; Hypertension; Lethal Dose 50; Mice; Rats | 1978 |
Antihypertensive thiadiazoles. 1. Synthesis of some 2-aryl-5-hydrazino-1,3,4-thiadiazoles with vasodilator activity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Decerebrate State; Hydrazines; Hypertension; Male; | 1988 |
Heterocyclic analogues of the antihypertensive beta-adrenergic blocking agent (S)-2-[3-(ter-butylamino)-2-hydroxypropoxy]-3-cyanopyridine.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Heart R | 1980 |
Antihypertensive indole derivatives of phenoxypropanolamines with beta-adrenergic receptor antagonist and vasodilating activity.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Hypertension; Indoles; Male; Propanol | 1980 |
Synthesis of some potential antihypertensive phthalazinyl- and quinoxalinylguanidines.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; | 1982 |
Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Biological Assay; Hypertension; Indicators and Reagen | 1983 |
Antihypertensives. N-1H-Pyrrol-1-yl-3-pyridazinamines.
Topics: Animals; Antihypertensive Agents; Dogs; Heart Rate; Hydralazine; Hypertension; Hypertension, Renal; | 1984 |
Antihypertensive activity of 6-arylpyrido[2,3-d]pyrimidin-7-amine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Pyridines; Pyrimidines; Rats; | 1981 |
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone.
Topics: Animals; Aorta; Female; Hydrazines; Hypertension; Male; Pyridazines; Rats; Rats, Wistar; Structure-A | 2009 |
The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof.
Topics: Aldosterone; Antihypertensive Agents; Doxazosin; Humans; Hydralazine; Hyperaldosteronism; Hypertensi | 2023 |
Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Carvedilol; Cohort Studies; Humans; Hydr | 2022 |
Glucagon-like peptide-1 receptor agonist, liraglutide, attenuated retinal thickening in spontaneously diabetic Torii fatty rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptide-1 R | 2022 |
Evaluation of presentation, treatment and outcome in hypertensive emergency in dogs and cats: 15 cases (2003-2019).
Topics: Amlodipine; Animals; Antihypertensive Agents; Blindness; Cat Diseases; Cats; Dog Diseases; Dogs; Eme | 2022 |
Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Ethnicity; Female; Humans; Hydralazine; Hypertension; Labet | 2022 |
Trends in antihypertensive prescription for pregnant women with hypertension and their peripartum outcomes before and after label and guideline revisions in Japan.
Topics: Antihypertensive Agents; Cesarean Section; Drug Prescriptions; Female; Humans; Hydralazine; Hyperten | 2022 |
Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Nicar | 2022 |
Overlapping drug-induced vasculitis, ANCA-associated vasculitis, and lupus nephritis caused by low-dose hydralazine.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; | 2023 |
Comparison of efficacy of intravenous labetalol and intravenous hydralazine for management of pre-eclampsia in pregnant women.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypotension; Lab | 2023 |
Improving the use of intravenous antihypertensive medications in the hospital setting: a quality improvement initiative for patient safety.
Topics: Administration, Intravenous; Antihypertensive Agents; Enalapril; Female; Health Personnel; Hospitals | 2019 |
Delay to Tissue Plasminogen Activator in Hypertensive Stroke Patients: An Analysis of Delay Duration Across Agents.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Female; Fibrinolytic Ag | 2020 |
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents; | 2020 |
Hydralazine-induced antineutrophil cytoplasmic antibody-associated vasculitis with pulmonary-renal syndrome: a case report.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Female; Glomerulonephritis; Hemorrhage; | 2020 |
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compound | 2020 |
Clinical Experiences of Intravenous Hydralazine and Labetalol for Acute Treatment of Severe Hypertension in Pregnant Thai Women.
Topics: Administration, Intravenous; Adult; Antihypertensive Agents; Apgar Score; Asian People; Blood Pressu | 2020 |
An Edematous and Ulcerative Eruption With Nasolabial Sparing in an Older Woman.
Topics: Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antihypertensive Agents; Biopsy; B | 2020 |
The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antihypertensive Agents; Blood Pre | 2020 |
Circadian rhythm of the intrarenal renin-angiotensin system is caused by glomerular filtration of liver-derived angiotensinogen depending on glomerular capillary pressure in adriamycin nephropathy rats.
Topics: Angiotensinogen; Animals; Circadian Rhythm; Doxorubicin; Glomerular Filtration Rate; Hydralazine; Hy | 2021 |
Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; | 2021 |
A Big Headache: An Unusual Case of Hypertensive Urgency in an Adolescent.
Topics: Adolescent; Amlodipine; Antihypertensive Agents; Aorta, Abdominal; Aortic Valve Stenosis; Computed T | 2021 |
Hydralazine-induced liver injury: a review and discussion.
Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Inj | 2021 |
Mineralocorticoid receptor antagonism protects the aorta from vascular smooth muscle cell proliferation and collagen deposition in a rat model of adrenal aldosterone-producing adenoma.
Topics: ACTH-Secreting Pituitary Adenoma; Aldosterone; Animals; Antihypertensive Agents; Aorta; Cell Prolife | 2018 |
Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Adrenergic Antagonists; Adult; Age | 2018 |
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
Topics: Aldosterone; Animals; Antihypertensive Agents; Disease Models, Animal; Endothelium; Fibrosis; Humans | 2018 |
Hydralazine-induced MPO-ANCA Renal-Limited Vasculitis Masquerading as Lupus Nephritis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Diagnosis, Differential; Fema | 2018 |
A Curious Case of Transient Movement Disorder.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Dyskinesias; Humans; Hydralazine; Hyperglycinemi | 2019 |
Renal T cell infiltration occurs despite attenuation of development of hypertension with hydralazine in Envigo's female Dahl rat maintained on a low-Na
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Diet, Sodium-Restricted; Disease Models, Animal | 2019 |
Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention.
Topics: Albumins; Animals; Atherosclerosis; Cardiovascular Diseases; Hydralazine; Hypertension; Lung Disease | 2013 |
Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response.
Topics: Animals; Biomarkers; Hemodynamics; Hydralazine; Hypertension; Kidney; Losartan; Rats; Rats, Transgen | 2013 |
Posterior reversible encephalopathy syndrome: 'a headache' on the AMU.
Topics: Aged; Antihypertensive Agents; Brain Edema; Disease Progression; Female; Headache; Humans; Hydralazi | 2013 |
Impact of high salt independent of blood pressure on PRMT/ADMA/DDAH pathway in the aorta of Dahl salt-sensitive rats.
Topics: Amidohydrolases; Animals; Antihypertensive Agents; Aorta; Arginine; Blood Pressure; Hydralazine; Hyp | 2013 |
Reduced hemodynamic load aids low-dose resveratrol in reversing cardiovascular defects in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Disease Model | 2013 |
Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hydral | 2014 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiot | 2014 |
Superoxide dismutase mimetic, tempol, aggravates renal injury in advanced-stage stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Benzimidazo | 2014 |
Roles of hypertension in the rupture of intracranial aneurysms.
Topics: Aneurysm, Ruptured; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Desoxycorticosteron | 2014 |
Mixed ligand complex via zinc(II)-mediated in situ oxidative heterocyclization of hydrochloride salt of 2-chlorobenzaldehyde hydralazine hydrazone as potential of antihypertensive agent.
Topics: Animals; Antihypertensive Agents; Benzaldehydes; Cobalt; Coordination Complexes; Copper; Crystallogr | 2014 |
Different phenotypes of the NAT2 gene influences hydralazine antihypertensive response in patients with resistant hypertension.
Topics: Acetylation; Adult; Aged; Antihypertensive Agents; Arylamine N-Acetyltransferase; Blood Pressure; Fe | 2014 |
The efficacy and safety of intravenous hydralazine for the treatment of hypertension in the hospitalized child.
Topics: Antihypertensive Agents; Blood Pressure; Child; Child, Preschool; Cohort Studies; Female; Heart Rate | 2014 |
Hydralazine associated pauci-immune glomerulonephritis.
Topics: Aged; Aged, 80 and over; Amlodipine; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Ant | 2014 |
Critical blood pressure threshold dependence of hypertensive injury and repair in a malignant nephrosclerosis model.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Drug Therapy, | 2014 |
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Topics: Animals; Collagen; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Diabetic Nephropathies; | 2015 |
Blockade of brain angiotensin II type 1 receptor inhibits the development of atrial fibrillation in hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; A | 2015 |
A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD Progression.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Disease Models, Animal; Disease Progression | 2015 |
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L | 2015 |
Beneficial effects of angiotensin-(1-7) against deoxycorticosterone acetate-induced diastolic dysfunction occur independently of changes in blood pressure.
Topics: Angiotensin I; Animals; Blood Pressure; Calcium; Calcium Signaling; Desoxycorticosterone Acetate; Di | 2015 |
Intravenous Hydralazine in Hospitalized Children and Adolescents with Hypertension.
Topics: Administration, Intravenous; Adolescent; Antihypertensive Agents; Blood Pressure; Child; Child, Hosp | 2016 |
Helping Hospitalized Patients with Hypertension: The Case for Hydralazine.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Male | 2016 |
Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Female; Fib | 2015 |
Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Arterioles; Bloo | 2016 |
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Hydralazine-Induced ANCA Vasculitis in the Setting of Acute Clostridium Difficile Infection.
Topics: Adrenal Cortex Hormones; Aged; Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Clos | 2016 |
Glucagon-induced hypertensive emergency: a case report.
Topics: Antihypertensive Agents; Emergencies; Female; Gastrointestinal Agents; Glucagon; Humans; Hydralazine | 2016 |
Controversies Regarding Diagnosis and Treatment of Severe Hypertension in Pregnancy.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Pre-E | 2017 |
Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzazepines; Bosentan; Endothelin-Converting Enzy | 2017 |
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dise | 2008 |
Hydralazine reduces leukocyte migration through different mechanisms in spontaneously hypertensive and normotensive rats.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Bod | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressu | 2008 |
Role of cardiac hypertrophy in reducing the sensitivity of cardiopulmonary reflex control of renal sympathetic nerve activity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Body Weight; Cardiomegaly; Enalapril; Heart; Hemodynam | 2008 |
Postpartum preeclampsia: emergency department presentation and management.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Antihypertensive Agents; Benzodiazepines; E | 2011 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Chronic intake of a phytochemical-enriched diet reduces cardiac fibrosis and diastolic dysfunction caused by prolonged salt-sensitive hypertension.
Topics: Analysis of Variance; Animals; Diet; Endomyocardial Fibrosis; Fruit; Heart Failure, Diastolic; Hydra | 2008 |
Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure | 2009 |
Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats.
Topics: Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimida | 2008 |
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
Azelnidipine decreases sympathetic nerve activity via antioxidant effect in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Antioxidants; Azetidinecarboxylic Acid; Bloo | 2008 |
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Ath | 2009 |
Evidence for a noradrenergic mechanism causing hypertension and abnormal glucose metabolism in rats with relative deficiency of gamma-melanocyte-stimulating hormone.
Topics: Animals; Bromocriptine; gamma-MSH; Glucose; Heart Rate; Hydralazine; Hypertension; Insulin; Male; No | 2009 |
Favorable cardiac and aortic remodeling in olmesartan-treated spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hydralazine; Hypertension; Imidazoles; Male; Myocy | 2009 |
Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cytokines; Diastole; Drug Therapy, | 2009 |
Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Brain; El | 2009 |
Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arginase; Blood Pressure; Body Weight; Brain; Enzyme Activation; H | 2009 |
High-salt diet increases plasma adiponectin levels independent of blood pressure in hypertensive rats: the role of the renin-angiotensin-aldosterone system.
Topics: Adiponectin; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Clonidine; | 2010 |
Hydralazine-induced ANCA-positive pauci-immune glomerulonephritis: a case report and literature review.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antihypertensive Agents; Female; Glomerulonephritis; Humans; | 2009 |
Treatment of hypertension in the inpatient setting: use of intravenous labetalol and hydralazine.
Topics: Adult; Aged; Antihypertensive Agents; Female; Hospitalization; Humans; Hydralazine; Hypertension; In | 2010 |
Effects of pregnancy, hypertension and nitric oxide inhibition on rat uterine artery myogenic reactivity.
Topics: Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Hydralazine; Hypertensio | 2010 |
Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic | 2010 |
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension.
Topics: Administration, Oral; Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pre | 2010 |
HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Echocardiography; Histone Deacetylas | 2010 |
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens | 2010 |
Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Collagen; Cyclic AMP-Dependent Protein | 2011 |
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Cyclic GMP; GTP Cyclohydrolase; Hydral | 2011 |
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.
Topics: Acetylglucosaminidase; Aldosterone; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cel | 2011 |
Tetrahydrobiopterin and hypertension: more than an emigrating story.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Drug Therapy, Combination; Humans; Hyd | 2011 |
Temporary treatment with AT1 receptor blocker, valsartan, from early stage of hypertension prevented vascular remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Arteries; Blood Vessels; Disease | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brai | 2011 |
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blo | 2012 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Sene | 2012 |
Hydralazine-induced lupus erythematosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Drug Therapy, Combination; F | 2012 |
Sympathoinhibition caused by orally administered telmisartan through inhibition of the AT₁ receptor in the rostral ventrolateral medulla of hypertensive rats.
Topics: Acetophenones; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertens | 2012 |
Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.
Topics: Acute Kidney Injury; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; | 2012 |
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial | 2012 |
EP1 disruption attenuates end-organ damage in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm; Blood Pressure; Desoxycorticoster | 2012 |
Blood pressure has only minor influence on aldosterone-induced oxidative stress and DNA damage in vivo.
Topics: Aldosterone; Animals; Apoptosis; Blood Pressure; Cell Transformation, Neoplastic; Cells, Cultured; C | 2013 |
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; | 2013 |
Hydralazine-induced lupus erythematosus: what is the mechanism?
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Humans; Hydralazine; Hypertension; Interl | 2012 |
48-year-old man with cough and leg swelling.
Topics: Acute Disease; Antihypertensive Agents; Cerebrovascular Circulation; Cough; Dyspnea; Echocardiograph | 2012 |
Effects of angiotensin II AT₁-receptor blockade on high fat diet-induced vascular oxidative stress and endothelial dysfunction in Dahl salt-sensitive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Di | 2013 |
Renal protective effects of α-calcitonin gene-related peptide in deoxycorticosterone-salt hypertension.
Topics: Animals; Arterial Pressure; Calcitonin Gene-Related Peptide; Chemokines; Cytokines; Desmin; Desoxyco | 2013 |
Persistent lowering of arterial pressure after continuous and intermittent therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug The | 2003 |
Brain nitric oxide synthase activity in spontaneously hypertensive rats during the development of hypertension.
Topics: Age Factors; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; An | 2003 |
Bladder disturbance due to apresoline.
Topics: Hydralazine; Hypertension; Urinary Bladder; Urination Disorders | 1952 |
Effects of a new vasodepressor ("apresoline") on blood pressure and renal function in children with acute nephritis.
Topics: Blood Pressure; Blood Pressure Determination; Hydralazine; Hypertension; Nephritis; Sympatholytics; | 1952 |
The place of the hydrazinophthalazine and thiophanium complications of pregnancy.
Topics: Hydralazine; Hypertension; Pregnancy; Sympatholytics | 1952 |
Evaluation of l-hydrazinophthalazine (apresoline) in treatment of hypertensive disease.
Topics: Hydralazine; Hypertension; Sympatholytics | 1952 |
Effect of hydralazine in hypertension.
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
Hexamethonium and apresoline (1-hydrazinophthalazine).
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1952 |
The control of hypertension with 1-hydrazinophthalazine (apresoline).
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
1-Hydrazinophthalazine; apresoline in the treatment of hypertension: a two year study.
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
The treatment of severe arterial hypertension with hexamethonium and hydrazinophthalazine.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholytics | 1953 |
[The treatment of severe arterial hypertension with hexamethonium and hydrazinophthalazine].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1952 |
Results with oral hexamethonium alone and in combination with 1-hydrazinophthalazine (apresoline) in the therapy of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
Some reactions to apresoline, hexamethonium and hydergine.
Topics: Cardiovascular Agents; Ergoloid Mesylates; Ergot Alkaloids; Hexamethonium; Hydralazine; Hypertension | 1952 |
Responses of the ballistocardiogram in hypertensive patients to the acute administration of apresoline, hexamethonium, veratrone, regitine and sodium amytal.
Topics: Amobarbital; Ballistocardiography; Barbiturates; Cardiovascular Agents; Hexamethonium; Hydralazine; | 1953 |
Pancytopenia following use of hydrallazine (apresoline).
Topics: Anemia; Anemia, Aplastic; Hydralazine; Hypertension; Pancytopenia; Sympatholytics; Tracheophyta | 1953 |
Apresoline intolerance with bladder paralysis.
Topics: Hydralazine; Hypertension; Paralysis; Sympatholytics; Urinary Bladder; Urinary Bladder, Neurogenic | 1953 |
Dibenzyline: results of therapy in patients with hypertension and a comparison with hexamethonium, 1-hydrazinophthalazine and semipurified extracts of veratrum.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Phenoxyb | 1953 |
Hydrallazine (apresoline) hydrochloride; pharmacological observations and clinical results in the therapy of hypertension.
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Salts; Sympatholytics | 1953 |
Essential hypertension; treatment with hexamethonium and apresoline.
Topics: Cardiovascular Agents; Essential Hypertension; Hexamethonium; Hydralazine; Hypertension; Muscle Rela | 1953 |
A preliminary report on clinical experiences with hexamethonium and 1-hydrazinophthalazine in the treatment of diastolic hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; | 1953 |
Death associated with hexamethonium and 1-hydrazinophthalazine (apresoline) therapy.
Topics: Cardiovascular Agents; Death; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; S | 1953 |
[Effects of apresoline on the circulation in hypertension and mitral valve stenosis].
Topics: Biological Phenomena; Constriction, Pathologic; Hydralazine; Hypertension; Mitral Valve; Mitral Valv | 1953 |
The use of hexemethonium chloride and 1-hydrazinophthalazine in the treatment of hypertension.
Topics: Cardiovascular Agents; Chlorides; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholyti | 1953 |
Acute psychosis as a complication of hydralazine therapy in essential hypertension.
Topics: Essential Hypertension; Hydralazine; Hypertension; Mental Disorders; Psychoses, Substance-Induced; P | 1953 |
A critical evaluation of the hypotensive asction of hydrallazine, hexamethonium, tetraethylammonium and dibenzyline salts in human and experimental hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypotension; Muscle Relaxants, Cent | 1953 |
Further observations on the effects of autonomic blocking agents in patients with hypertension. I. General systemic effects of hexamethonium, pentamethonium, and hydrazinophthalazine.
Topics: Bis-Trimethylammonium Compounds; Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Mu | 1953 |
Clinical use of hydralazine and hexamethonium in treatment of hypertension.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
The effects of 1-hydrazinophthalazine on cerebral blood flow, vascular resistance, oxygen uptake and jugular oxygen tension in hypertensive subjects.
Topics: Cerebrovascular Circulation; Hydralazine; Hypertension; Oxygen; Sympatholytics; Vascular Resistance | 1953 |
[Effect of hydrazinophthalazine on arterial pressure in hypertension].
Topics: Arterial Pressure; Blood Pressure; Hydralazine; Hypertension; Sympatholytics | 1953 |
[Hydrazinophthalazine in hypertension; clinical studies].
Topics: Biomedical Research; Hydralazine; Hypertension; Sympatholytics | 1953 |
Treatment of hypertension with hexamethonium alone and in combination with apresoline.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
Arterial hypertension: the therapeutic effect of sodium restriction combined with 1-hydrazinophthalazine or dibenzyline.
Topics: Diet; Hydralazine; Hypertension; Phenoxybenzamine; Sodium; Sympatholytics | 1953 |
[Therapy of hypertension with hydrazinophthalazines].
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
The treatment of hypertension with 1-hydrazinophthalazine (apresoline).
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1953 |
The treatment of hypertension with hexamethonium and hydrazinophthalazine (apresoline).
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
[1-Hydrazinophthalazine hydrochloride in the treatment of hypertension].
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
[Therapy of hypertension with hydrazinophthalazine].
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
[Effect of hypotensive nepresol on heart volume and vascular resistance in hypertensive patients].
Topics: Blood Circulation; Cardiac Volume; Heart; Hydralazine; Hypertension; Hypotension; Sympatholytics; Va | 1953 |
Effects of apresoline, veratrum alkaloids, high spinal anesthesia, and arfonad on renal hemodynamics of pregnant patients with toxemia and essential hypertension.
Topics: Anesthesia, Spinal; Essential Hypertension; Female; Hemodynamics; Hydralazine; Hypertension; Pre-Ecl | 1953 |
Newer drugs in hypertension; combined effects of 1-hydrazinophthalazine (apresoline) and hexamethonium salts; a preliminary report.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Salts; S | 1953 |
Toxic effects of 1-hydrazinophthalazine in ambulatory hypertensive patients.
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1953 |
1-Hydrazinophthalazine (apresoline) in the treatment of hypertensive disease: a clinical trial with a control group.
Topics: Control Groups; Hydralazine; Hypertension; Sympatholytics | 1953 |
Modification of the hypotensive action of 1-hydrazinophthalazine (apresoline) by priscoline, hexamethonium and section of the carotid sinus and aortic buffer nerves in normal and renal hypertensive dogs.
Topics: Animals; Aorta; Carotid Sinus; Dogs; Hexamethonium; Hydralazine; Hypertension; Kidney; Muscle Relaxa | 1953 |
Rheumatic and febrile syndrome during prolonged hydralazine treatment.
Topics: Adrenocorticotropic Hormone; Cortisone; Hydralazine; Hypertension; Rheumatic Diseases; Sympatholytic | 1954 |
Hexamethonium and apresoline; their effects on ambulatory hypertensive patients.
Topics: Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; | 1953 |
Outpatient treatment of hypertension with hexamethonium and apresoline.
Topics: Ambulatory Care; Cardiovascular Agents; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Rel | 1953 |
[Results of treatment of arterial hypertension with hexamethonium and apresoline].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1953 |
[Hypotonic effect of combined apresoline and phlebotomy].
Topics: Hydralazine; Hypertension; Muscle Hypotonia; Phlebotomy; Sympatholytics | 1953 |
The use of apresoline in the hypertensive arteriosclerotic syndrome.
Topics: Aged; Hydralazine; Hypertension; Sympatholytics; Syndrome | 1954 |
Syndrome simulating collagen disease caused by hydralazine (Apresoline).
Topics: Collagen; Collagen Diseases; Hydralazine; Hypertension; Sympatholytics; Syndrome | 1954 |
Response of metacorticoid hypertension to bistrium, apresoline, veriloid and serpentina.
Topics: Alkaloids; Hydralazine; Hypertension; Hypnotics and Sedatives; Muscle Relaxants, Central; Rauwolfia; | 1953 |
Arterial hypertension: the therapeutic effect of sodium restriction combined with 1-hydrazinophthalazine or dibenzyline.
Topics: Anions; Hydralazine; Hypertension; Ions; Phenoxybenzamine; Sodium; Sodium, Dietary; Sympatholytics | 1954 |
Hexamethonium and hydralazine hydrochloride for treatment of hypertension.
Topics: Cardiovascular Agents; Constipation; Hexamethonium; Hydralazine; Hypertension; Hypotension, Orthosta | 1954 |
1-Hydrazinophthalazine (apresoline) in hypertension.
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
[Clinico-experimental research on circulatory action of some hydrazinophthalazine derivatives with hypotensive action].
Topics: Antihypertensive Agents; Female; Hydralazine; Hypertension; Hypotension; Pregnancy; Pregnancy Compli | 1953 |
[Treatment of arterial hypertension with derivatives of hydrazinophthalazine: C. 5968-C. 7441].
Topics: Hydralazine; Hypertension; Sympatholytics | 1953 |
Some effects of a hypotensive agent (1-hydrazinophthalazine: C5968: apresoline) on the haemodynamics of hypertensive subjects.
Topics: Antihypertensive Agents; Blood Pressure; Electrocardiography; Heart; Heart Rate; Hydralazine; Hypert | 1953 |
Further evaluation of hydralazine in treatment of hypertensive disease.
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
Experience with hydrazinophthalazine in hypertensive states of pregnancy.
Topics: Female; Hydralazine; Hypertension; Pregnancy; Pregnancy Complications; Sympatholytics | 1954 |
The effect of prolonged sodium depletion and of hydralazine hydrochloride and hexamethonium bromide on the digital vascular resistance in primary hypertension.
Topics: Essential Hypertension; Fingers; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1954 |
[Use of hydrazinophthalazine in essential hypertension].
Topics: Essential Hypertension; Hydralazine; Hypertension; Sympatholytics | 1953 |
[Effect of hypotensive drugs on stroke volume and vascular resistance in hypertension. II. Reserpin (Serpasil-Ciba) and its combination with Nepresol].
Topics: Antihypertensive Agents; Blood Circulation; Heart; Hydralazine; Hypertension; Rauwolfia; Reserpine; | 1954 |
[Early results of 1-hydrazinophthalazine in arterial hypertension].
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Therapy of arterial hypertension with derivatives of hydrazinophthalazine].
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hydrazinophthalazine derivatives in hypertension and in various vascular diseases; critical review and clinical observations].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Peripheral Vascular Diseases; Sympatholytics; Va | 1953 |
Bleeding peptic ulcer complicating hydralazine and hexamethonium bromide therapy.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Peptic Ulcer; Peptic Ulcer Hemo | 1954 |
Late reaction to hydralazine (Apresoline) therapy.
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
Renal and hypotensive effects of acute and chronic oral treatment with 1-hydrazinophthalazine (apresoline) in hypertension.
Topics: Administration, Oral; Humans; Hydralazine; Hypertension; Hypotension; Kidney; Sympatholytics | 1954 |
[Effect of hydrazinophthalazine on intrarenal hemodynamics in essential hypertension].
Topics: Cardiovascular System; Essential Hypertension; Hemodynamics; Hydralazine; Hypertension; Kidney; Symp | 1954 |
The hemodynamic and metabolic response of the human hypertensive kidney to a standard dose of 1-hydrazinophthalazine (hydralazine).
Topics: Hemodynamics; Hydralazine; Hypertension; Kidney; Sympatholytics | 1954 |
[Results of therapy of hypertension with apresoline in persons over 60].
Topics: Aged; Disease; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hemodynamics changes after acute and chronic application of hydrazinophthalazine preparations].
Topics: Cardiovascular System; Hemodynamics; Hydralazine; Hypertension; Sympatholytics | 1954 |
The use of 1-hydrazinophthalazine (apresoline) in the management of hypertension appearing early in pregnancy.
Topics: Disease Management; Female; Hydralazine; Hypertension; Pregnancy; Pregnancy Complications; Sympathol | 1954 |
Apresoline (hydralazine hydrochloride) and its use in cases of hypertensive pregnancy.
Topics: Eclampsia; Female; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Sympatholytics | 1954 |
Clinical evaluation of hydralazine (apresoline) alone and in combination with veriloid in the treatment of hypertension.
Topics: Hydralazine; Hypertension; Sympatholytics; Veratrum Alkaloids | 1954 |
[Trial of hydrazinophthalazine therapy of hypertension in two cases of grave eclampsia].
Topics: Eclampsia; Female; Hydralazine; Hypertension; Pregnancy; Sympatholytics | 1953 |
Febrile syndrome during prolonged hydralazine treatment for hypertension.
Topics: Adrenocorticotropic Hormone; Cortisone; Fever; Hydralazine; Hypertension; Sympatholytics | 1954 |
Current therapeutics. LXXX. Hydralazine in the control of severe hypertension.
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hexamethonium, apresoline and pyretotherapy in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hyperthermia, Induced; Muscle Relax | 1954 |
Outpatient treatment of hypertension with hexamethonium and hydralazine; a preliminary report.
Topics: Ambulatory Care; Hexamethonium; Humans; Hydralazine; Hypertension; Muscle Relaxants, Central; Outpat | 1954 |
Treatment of elderly hypertensive patients with hydralazine (apresoline) hydrochloride.
Topics: Aged; Disease; Humans; Hydralazine; Hypertension; Patients; Salts; Sympatholytics | 1954 |
[Clinical trial of a new hypotensive drug, 1-hydrazinophthalazine (apresoline)].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Hypotension; Sympatholytics | 1954 |
[Ambulant treatment of hypertension with hydrazinophthalazine derivatives].
Topics: Antihypertensive Agents; Autonomic Agents; Hydralazine; Hypertension; Sympatholytics | 1954 |
Studies on the control of hypertension by hyphex. III. Pharmacological and chemical observations on 1-hydrazinophthalazine.
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
[Experimental hydralazine therapy of hypertension in two cases of severe eclampsia].
Topics: Eclampsia; Female; Hydralazine; Hypertension; Pregnancy; Sympatholytics; Therapies, Investigational | 1954 |
[The treatment of hypertension with nepresol].
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
A comparison of the effects of hexamethonium alone and in combination with 1-hydrazinophthalazine (apresoline) in the treatment of hypertension.
Topics: Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholytics | 1953 |
[Apresoline therapy of essential hypertension].
Topics: Essential Hypertension; Hydralazine; Hypertension; Sympatholytics | 1954 |
Treatment of hypertensive disease with hydralazine; comparison of its action with that of low sodium diet in hospitalized patients.
Topics: Diet; Diet, Sodium-Restricted; Humans; Hydralazine; Hypertension; Patients; Sodium; Sodium, Dietary; | 1954 |
[Comparative clinical studies on the effect of hydrazinophthalazine and Rauwolfia alkaloid reserpin on the blood pressure].
Topics: Blood Pressure; Blood Pressure Determination; Hydralazine; Hypertension; Hypnotics and Sedatives; Ra | 1954 |
Hexamethonium and apresoline (L-hydrazinophthalazine) in the treatment of malignant hypertension; report of a case.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Rel | 1954 |
Hemodynamic effects of 1-hydrazinophthalazine in patients with arterial hypertension.
Topics: Blood Circulation; Hemodynamics; Hydralazine; Hypertension; Sympatholytics | 1955 |
Treatment of hypertension with oral reserpine alone and in combination with hydralazine or hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Hypnotics and Sedatives; Muscle Rel | 1955 |
Combined Rauwolfia-hydralazine therapy of hypertensive patients.
Topics: Hydralazine; Hypertension; Hypnotics and Sedatives; Rauwolfia; Sympatholytics | 1955 |
[Nepresol: one tablet contains 25 mg. of 1,4-dihydrazinophthalazine].
Topics: Hydralazine; Hypertension; Sympatholytics; Tablets | 1954 |
[Medicinal therapy of hypertension. II. Preliminary communication on antihypertensive properties of hydrazinophthalazine drugs].
Topics: Antihypertensive Agents; Communication; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hydrazinophthalazine in therapy of hypertension].
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Clinical trials with 1-hydrazinophthalazine and with 1,4-dihydrazinophthalazine in arterial hypertension].
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Effectiveness of hydrazinophthalazine in control of arterial hypertension].
Topics: Humans; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hydrazinophthalazine in therapy of senile arterial hypertension; clinico-statistical study].
Topics: Aged; Humans; Hydralazine; Hypertension; Sympatholytics | 1954 |
[Hydralazine (apresoline) in arterial hypertension].
Topics: Hydralazine; Hypertension; Sympatholytics | 1954 |
[1-Hydrazinophthalazine and Veratrum viride in the treatment of arterial hypertension].
Topics: Hydralazine; Hypertension; Sympatholytics; Veratrum; Veratrum Alkaloids | 1954 |
[Early results of therapy of arterial hypertension with pentolinium alone and combined with hydrazinophthalazine and Rauwolfia].
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Hypnotics and Sedatives; Muscle Relaxants, Central | 1954 |
[Combined 1-hydrazinophthalazine and Rauwolfia serpentina in therapy of arterial hypertension].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Rauwolfia; Secologanin Tryptamine Alkaloids; Sym | 1955 |
[Reserpine (serpasil) alone and combined with apresoline, in ambulant therapy of hypertension].
Topics: Antihypertensive Agents; Exercise Therapy; Humans; Hydralazine; Hypertension; Reserpine; Secologanin | 1955 |
Effect of reserpine (serpasil) and hydralazine (apresoline) on experimental steroid hypertension.
Topics: Antihypertensive Agents; Desoxycorticosterone; Hydralazine; Hypertension; Reserpine; Secologanin Try | 1955 |
Newer drugs in the treatment of hypertension. II. Use of hexamethonium in combination with hydralazine.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1955 |
The effect of oral 1-hydrazinophthalazine therapy on renal function in essential vascular hypertension.
Topics: Essential Hypertension; Humans; Hydralazine; Hypertension; Kidney; Sympatholytics | 1955 |
Depression of cholesterol levels in human plasma following ethylenediamine tetracetate and hydralazine.
Topics: Acetates; Arteriosclerosis; Blood; Cholesterol; Depressive Disorder; Ethylenediamines; Humans; Hydra | 1955 |
The drug treatment of severe hypertensive disease, with particular reference to hydralazine and pentapyrrolidinium.
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatholytics | 1955 |
Treatment of hypertension with reserpine (serpasil) alone and in combination with hydralazine (apresoline).
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Reserpine; Secologanin Tryptamine Alkaloids; Sym | 1955 |
The effect of reserpine and its combination with hydralazine on blood pressure and renal hemodynamics during the hypertensive phase of acute nephritis in children.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Child; Humans; Hydralazine; H | 1956 |
[Apresoline in the treatment of arterial hypertension].
Topics: Hydralazine; Hypertension; Sympatholytics | 1955 |
Reserpine-hydralazine combination therapy of hypertensive disease, with hydralazine in doses generally below the toxic range.
Topics: Antihypertensive Agents; Combined Modality Therapy; Hydralazine; Hypertension; Reserpine; Secologani | 1956 |
Clinical observations on the oral use of hexamethonium, hydralazine, and rauwolfia extracts in essential hypertension.
Topics: Antihypertensive Agents; Essential Hypertension; Hexamethonium; Humans; Hydralazine; Hypertension; M | 1956 |
[Treatment of arterial hypertension with reserpine and hydrazinophthalazine].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Reserpine; Secologanin Tryptamine Alkaloids; Sym | 1956 |
Further experience with apresoline in toxemia and hypertension of pregnancy.
Topics: Female; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Sepsis; Sympat | 1956 |
[Hydrazinophthalazine compounds in the treatment of hypertension in obstetrics and gynecology].
Topics: Female; Gynecology; Humans; Hydralazine; Hypertension; Kidney Diseases; Obstetrics; Pregnancy; Pregn | 1956 |
[Significance of piezogram in indications and results of the treatment of hypertension with hydralazine and reserpine].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Reserpine; Secologanin Tryptamine Alkaloids; Sym | 1956 |
[Effect of hydrazinophthalazine on renal circulation in arterial hypertension].
Topics: Hydralazine; Hydrazines; Hypertension; Kidney; Renal Circulation | 1956 |
[Combined Rauwolfia-hydrazinophthalazine (ipharon) therapy].
Topics: Alkaloids; Hydralazine; Hypertension; Hypnotics and Sedatives; Rauwolfia | 1956 |
[Combined Rauwolfia-hydrazinophthalazine (ipharon) therapy].
Topics: Alkaloids; Hydralazine; Hypertension; Hypnotics and Sedatives; Rauwolfia | 1956 |
[Combined Rauwolfia-hydrazinophthalazine (ipharon) therapy].
Topics: Alkaloids; Hydralazine; Hypertension; Hypnotics and Sedatives; Rauwolfia | 1956 |
[Combined Rauwolfia-hydrazinophthalazine (ipharon) therapy].
Topics: Alkaloids; Hydralazine; Hypertension; Hypnotics and Sedatives; Rauwolfia | 1956 |
Pulmonary disease following chronic chemical ganglionic blockade; a clinical and pathologic study.
Topics: Bis-Trimethylammonium Compounds; Hydralazine; Hypertension; Lung; Lung Diseases | 1957 |
Pulmonary disease following chronic chemical ganglionic blockade; a clinical and pathologic study.
Topics: Bis-Trimethylammonium Compounds; Hydralazine; Hypertension; Lung; Lung Diseases | 1957 |
Pulmonary disease following chronic chemical ganglionic blockade; a clinical and pathologic study.
Topics: Bis-Trimethylammonium Compounds; Hydralazine; Hypertension; Lung; Lung Diseases | 1957 |
Pulmonary disease following chronic chemical ganglionic blockade; a clinical and pathologic study.
Topics: Bis-Trimethylammonium Compounds; Hydralazine; Hypertension; Lung; Lung Diseases | 1957 |
[Psychosomatic action of chlorpromazine and reserpine].
Topics: Chlorpromazine; Humans; Hydralazine; Hypertension; Psychophysiologic Disorders; Reserpine | 1956 |
[Psychosomatic action of chlorpromazine and reserpine].
Topics: Chlorpromazine; Humans; Hydralazine; Hypertension; Psychophysiologic Disorders; Reserpine | 1956 |
[Psychosomatic action of chlorpromazine and reserpine].
Topics: Chlorpromazine; Humans; Hydralazine; Hypertension; Psychophysiologic Disorders; Reserpine | 1956 |
[Psychosomatic action of chlorpromazine and reserpine].
Topics: Chlorpromazine; Humans; Hydralazine; Hypertension; Psychophysiologic Disorders; Reserpine | 1956 |
[Decrease in blood pressure after parenteral trial doses of reserpine (serpasil), hydralazine (apresolin), and pentapyrrolidin (ansolysen) in patients with arterial hypertension, with special reference to the value of the test as an indicator of the clini
Topics: Aged; Blood Pressure; Blood Pressure Determination; Humans; Hydralazine; Hypertension; Muscle Relaxa | 1956 |
[Decrease in blood pressure after parenteral trial doses of reserpine (serpasil), hydralazine (apresolin), and pentapyrrolidin (ansolysen) in patients with arterial hypertension, with special reference to the value of the test as an indicator of the clini
Topics: Aged; Blood Pressure; Blood Pressure Determination; Humans; Hydralazine; Hypertension; Muscle Relaxa | 1956 |
[Decrease in blood pressure after parenteral trial doses of reserpine (serpasil), hydralazine (apresolin), and pentapyrrolidin (ansolysen) in patients with arterial hypertension, with special reference to the value of the test as an indicator of the clini
Topics: Aged; Blood Pressure; Blood Pressure Determination; Humans; Hydralazine; Hypertension; Muscle Relaxa | 1956 |
[Decrease in blood pressure after parenteral trial doses of reserpine (serpasil), hydralazine (apresolin), and pentapyrrolidin (ansolysen) in patients with arterial hypertension, with special reference to the value of the test as an indicator of the clini
Topics: Aged; Blood Pressure; Blood Pressure Determination; Humans; Hydralazine; Hypertension; Muscle Relaxa | 1956 |
Hypertension.
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
Hypertension.
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
Hypertension.
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
Hypertension.
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
Effect of blood pressure depressants on plasma proteins in hypertensive diseases.
Topics: Blood Pressure; Blood Proteins; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Veratrum | 1956 |
Effect of blood pressure depressants on plasma proteins in hypertensive diseases.
Topics: Blood Pressure; Blood Proteins; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Veratrum | 1956 |
Effect of blood pressure depressants on plasma proteins in hypertensive diseases.
Topics: Blood Pressure; Blood Proteins; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Veratrum | 1956 |
Effect of blood pressure depressants on plasma proteins in hypertensive diseases.
Topics: Blood Pressure; Blood Proteins; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Veratrum | 1956 |
A clinical evaluation of antihypertensive drugs.
Topics: Antihypertensive Agents; Autonomic Agents; Hydralazine; Hypertension; Reserpine | 1957 |
[1-Hydrazinophthalazine; its effect on hypertension].
Topics: Hydralazine; Hypertension | 1957 |
[Combined use of serpasil & apresoline in hypertension].
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
The effect of exercise in the supine position on cardiovascular and renal function in hypertensive patients before and during chronic oral hydralazine therapy.
Topics: Cardiovascular System; Exercise; Heart Function Tests; Humans; Hydralazine; Hypertension; Kidney; Su | 1957 |
[Treatment of hypertension with apresoline].
Topics: Hydralazine; Hypertension | 1957 |
[Modern medications of arterial hypertension. III. Treatment with derivatives of hydrazine].
Topics: Humans; Hydralazine; Hydrazines; Hypertension; Monitoring, Physiologic; Sympatholytics | 1957 |
[Clinical aspects of the use of hypotensive drugs in therapy of arterial hypertension].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Reserpine; Veratrum Alkaloids | 1957 |
[Treatment of hypertension with apresoline and ganglion blocking agents].
Topics: Autonomic Agents; Ganglionic Blockers; Hydralazine; Hypertension | 1957 |
[Result of the treatment of hypertension with carbo-ethoxy hydrazino phthalazine hydrochloride].
Topics: Charcoal; Humans; Hydralazine; Hypertension; Phthalazines | 1957 |
[Treatment of arterial hypertension with 1-hydrazinophthalazine (apresoline)].
Topics: Hydralazine; Hypertension | 1957 |
[Adelphan in therapy of hypertension].
Topics: Humans; Hydralazine; Hypertension; Reserpine; Sympatholytics | 1957 |
Antihypertension therapy in toxemia of pregnancy; a 30 month progress report.
Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Research Report; Veratrum Alkal | 1957 |
[Prolonged treatment of hypertension with methonium salts alone & combined with other hypotensive drugs].
Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Hydralazine; Hypertension; Reserpine; Salt | 1957 |
[Combined treatment of arterial hypertension; 1-hydrazinophthalazine + reserpine].
Topics: Combined Modality Therapy; Hydralazine; Hypertension; Manipulation, Osteopathic; Reserpine | 1957 |
[Combined serpasil, apresoline and verlloid therapy of hypertensive form of glomerulonephritis].
Topics: Antihypertensive Agents; Glomerulonephritis; Humans; Hydralazine; Hypertension; Reserpine | 1957 |
[Combined medication over a long period in severe non-malignant hypertension].
Topics: Aged; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Relaxants, Central; Reserpi | 1957 |
[Ambulant reserpine & hydralazine therapy of mild hypertension over a long period].
Topics: Aged; Exercise Therapy; Humans; Hydralazine; Hypertension; Reserpine | 1957 |
Electrolyte and water excretion in arterial hypertension. II. Studies in subjects with essential hypertension after antihypertensive drug treatment.
Topics: Antihypertensive Agents; Body Fluids; Electrolytes; Essential Hypertension; Hexamethonium Compounds; | 1958 |
Newer drugs in the treatment of hypertension. IV. Use of reserpine, hydralazine, and pentolinium in various combinations.
Topics: Cardiovascular Agents; Dermatologic Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Pe | 1958 |
Lesions in the hypertensive rat kidney produced by hydralazine.
Topics: Animals; Hydralazine; Hypertension; Kidney Diseases; Rats | 1958 |
[Apresoline in the treatment of hypertension caused by glomerulonephritis in children].
Topics: Glomerulonephritis; Humans; Hydralazine; Hypertension | 1957 |
[Hypotensen therapy of hypertension].
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Neostigmine; Reserpine | 1957 |
[Problems of hypertension and combination therapy].
Topics: Combined Modality Therapy; Hydralazine; Hypertension; Reserpine | 1957 |
Long-term combined drug therapy in non-malignant hypertension.
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Hypertension, Malignant; Muscle Relaxants, Central | 1958 |
[Effects of digestive activities on blood pressure regulation in hypertension under the effects of reserpine and phthalazine bodies].
Topics: Blood Pressure; Digestion; Gastrointestinal Tract; Hydralazine; Hypertension; Phthalazines; Reserpin | 1958 |
[Notes on neurolytic drugs in therapy of arterial hypertension].
Topics: Autonomic Agents; Hexamethonium Compounds; Hydralazine; Hypertension; Neurosurgical Procedures; Rese | 1958 |
[Combined reserpine-hydrazinophthalazine in therapy of hypertension in private practice].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Private Practice; Reserpine | 1958 |
Combined hydrallazine and reserpine in the therapy of hypertension.
Topics: Hydralazine; Hypertension; Reserpine | 1957 |
[Clinical evaluation of the new drugs used in therapy of arterial hypertension; combined reserpine and hydrazinophthalazine].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Reserpine | 1958 |
The effect of hydralazine (L-hydrazinophthalazine) on the kidneys of rats treated with cortexone.
Topics: Animals; Desoxycorticosterone; Hydralazine; Hypertension; Kidney; Rats | 1958 |
[Content of isolated & combined short-term reserpine & dihydrazinophthalazine administration in circulatory hypertensive diseases].
Topics: Cardiovascular Diseases; Combined Modality Therapy; Hydralazine; Hypertension; Manipulation, Osteopa | 1958 |
[Critical remarks on the treatment of hypertension with hypotensive substances].
Topics: Antihypertensive Agents; Humans; Hydralazine; Hypertension; Secologanin Tryptamine Alkaloids | 1958 |
[Medicinal treatment of hypertension].
Topics: Antihypertensive Agents; Humans; Hydralazine; Hypertension; Secologanin Tryptamine Alkaloids | 1958 |
Adelphane in essential hypertension.
Topics: Dihydralazine; Drug Combinations; Essential Hypertension; Humans; Hydralazine; Hypertension; Reserpi | 1958 |
The role of reserpine in essential hypertension when used alone or combined with hydralazine.
Topics: Essential Hypertension; Hydralazine; Hypertension; Reserpine | 1958 |
Pressor effect of subcutaneous renin in dogs, and effect of reserpine, 1-hydrazinophthalazine and hexamethonium on renin hypertension.
Topics: Animals; Dogs; Endopeptidases; Hexamethonium; Hexamethonium Compounds; Hydralazine; Hydrolases; Hype | 1959 |
Effect of antihypertensive drugs on the tissue respiration of normal and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Azides; Hydralazine; Hypertension; Kidney; Myocardium; Rats; Reser | 1959 |
[Use of hydrazinophthalazine in hypertensive and arteriosclerotic retinopathy].
Topics: Arteriosclerosis; Hydralazine; Hypertension; Retina; Retinal Diseases | 1958 |
[Treatment of hypertension in old age with serpasil & adelphan].
Topics: Aged; Humans; Hydralazine; Hypertension; Reserpine | 1959 |
[Chlorisondamine in the treatment of arterial hypertension].
Topics: Autonomic Agents; Chlorisondamine; Hydralazine; Hypertension; Reserpine | 1959 |
[Result of treatment of arterial hypertension with hexamethonium, thalazine & other drugs].
Topics: Hexamethonium; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Hypertension, Portal | 1959 |
[Hydralazine syndrome after prolonged treatment with adelphan].
Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine | 1961 |
[Contribution to the treatment of arterial hypertension with the use of a combination of hypotensive drugs].
Topics: Chlorothiazide; Humans; Hydralazine; Hypertension; Reserpine | 1961 |
Prolonged hydralazine hydrochloride administration in 132 hypertensive patients--Study of toxicity.
Topics: Humans; Hydralazine; Hypertension | 1960 |
Hydralazine in the treatment of hypertension.
Topics: Humans; Hydralazine; Hypertension | 1961 |
[Results in the therapy of hypertension with reserpine, dihydrazinophthalazine, a combination of both and placebos].
Topics: Hydralazine; Hypertension; Reserpine | 1959 |
Effect of the addition of hydralazine or chlorothiazide to ganglionic blocking agents in the treatment of severe hypertension.
Topics: Chlorothiazide; Ganglionic Blockers; Hydralazine; Hypertension | 1959 |
The use of syrosingopine (SU-3118) and hydralazine in ambulatory hypertensive patients.
Topics: Hydralazine; Hypertension; Reserpine | 1960 |
The relationship between intermittent hypotension and the prevention by hydralazine of acute vascular disease in rats with steroid hypertension.
Topics: Animals; Hydralazine; Hypertension; Hypotension; Peripheral Vascular Diseases; Rats; Vascular Diseas | 1960 |
Transient myopia during treatment for hypertension with autonomic blocking agents.
Topics: Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Myopia | 1960 |
Studies on cerebral circulation and metabolism in hypertensive diseases. III. The effect of prolonged oral administration of hypotensive agents upon the cerebral circulation and metabolism in patients with essential hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Brain; Cerebrovascular Circulation; Essential Hyperte | 1959 |
[Adelphan esidrex in medical practice].
Topics: Chlorothiazide; Drug Combinations; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1960 |
[A new hypotensive drug: guanethidine. Its association with the hydralazines].
Topics: Amidines; Antihypertensive Agents; Guanethidine; Hydralazine; Hypertension; Hypotension | 1961 |
[Combined treatment of arterial hypertension (guanethidine, hydralazine, reserpine, saluretics)].
Topics: Amidines; Antihypertensive Agents; Combined Modality Therapy; Diuretics; Guanethidine; Hydralazine; | 1962 |
[Combined treatment of hypertension].
Topics: Chlorothiazide; Combined Modality Therapy; Hydralazine; Hypertension; Manipulation, Osteopathic; Nut | 1962 |
[Reserpine-hydrazinophthalazine-hydrochlorothiazide combination in the treatment of hypertension].
Topics: Chlorothiazide; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1962 |
[Comparative study of the effectiveness of drug therapy in hypertensive disease].
Topics: Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine; Vasodilator Agents | 1963 |
Effect of medical treatment of severe hypertension. A follow-up study of 161 patients with group 3 and group 4 hypertension.
Topics: Follow-Up Studies; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Hypertension, Maligna | 1963 |
Arteriolar necrosis in adrenal-regeneration hypertension: influence of preventive treatment with hydralazine on tissue electrolvtes.
Topics: Adrenal Gland Diseases; Adrenalectomy; Chlorides; Humans; Hydralazine; Hypertension; Potassium; Rege | 1963 |
Hydralazine lupus syndrome associated with a possible antihydralazine antibody.
Topics: Angina Pectoris; Antibodies; Humans; Hydralazine; Hypertension; Immunoglobulins; Lupus Erythematosus | 1962 |
Systemic hypertension. Present status of medical management.
Topics: Chlorothiazide; Ganglionic Blockers; Guanethidine; Hydralazine; Hypertension; Hypertension, Renal; R | 1962 |
A broad ranged antihypertensive combination (Ser-Ap-Es).
Topics: Antihypertensive Agents; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1963 |
[Medical treatment of essential hypertension. 4-year case material].
Topics: Chlorothiazide; Essential Hypertension; Humans; Hydralazine; Hypertension; Mecamylamine; Reserpine | 1962 |
[On the treatment of arterial hypertension with a combination of mebutamate, reserpine and hydralazine].
Topics: Anti-Anxiety Agents; Antihypertensive Agents; Antipsychotic Agents; Carbamates; Hydralazine; Hyperte | 1963 |
[Treatment of hypertension with 2 new preparations].
Topics: Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1962 |
Vascular lesions in experimental renal hypertension, with special reference to effect of hypotensive treatment.
Topics: Arteries; Cerebral Hemorrhage; Coronary Vessels; Guanethidine; Humans; Hydralazine; Hydrochlorothiaz | 1963 |
Current drug therapy in hypertension.
Topics: Diuretics; Ganglionic Blockers; Guanethidine; Hydralazine; Hypertension; Rauwolfia; Veratrum | 1963 |
[Treatment of grave hypertensive states with the association of guanethidine and hydrazinophthalazine].
Topics: Guanethidine; Humans; Hydralazine; Hypertension | 1963 |
[On the therapy of hypertensive encephalopathy].
Topics: Brain Diseases; Humans; Hydralazine; Hypertension; Hypertensive Encephalopathy | 1963 |
Indications for treatment and present-day drug therapy in essential hypertension.
Topics: Diet, Sodium-Restricted; Dihydroxyphenylalanine; Essential Hypertension; Ganglionic Blockers; Guanet | 1963 |
CHEMOTHERAPY OF HYPERTENSION: YESTERDAY--TODAY--TOMORROW.
Topics: Alkaloids; Amines; Antihypertensive Agents; Chlorisondamine; Chlorothiazide; Dihydroxyphenylalanine; | 1963 |
[ON THE COMBINED PHARMACOLOGICAL TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Antipsychotic Agents; Carbamates; Humans; Hydralazine; Hypertension; Reserp | 1963 |
[CURRENT THERAPY OF HYPERTENSION].
Topics: Antihypertensive Agents; Benzothiadiazines; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; | 1963 |
[MEBUTAMATE ASSOCIATIONS IN ANTIHYPERTENSIVE THERAPY].
Topics: Antihypertensive Agents; Antipsychotic Agents; Carbamates; Ethylenediamines; Humans; Hydralazine; Hy | 1963 |
[HYPERTENSION AND ANTIHYPERTENSIVE AGENTS].
Topics: Antihypertensive Agents; Diuretics; Ganglionic Blockers; Hydralazine; Hypertension; Methyldopa; Nitr | 1963 |
OFFICE EVALUATION OF THE HYPERTENSIVE PATIENT. II.
Topics: Aging; Blood Pressure; Blood Pressure Determination; Central Nervous System; Diuretics; Fundus Oculi | 1963 |
CARCINOMA AND HYDRALAZINE TOXICITY IN PATIENTS WITH MALIGNANT HYPERTENSION.
Topics: Breast Neoplasms; Carcinoma; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Lung Neopla | 1963 |
[EFFECTS OF THE ASSOCIATION OF RESERPINE AND 1-4 DIHYDRAZINOPHTHALAZINE SULFATE)].
Topics: Blood Chemical Analysis; Blood Proteins; Diuresis; Hydralazine; Hypertension; Nitrogen; Reserpine; S | 1963 |
[CLINICAL STUDY OF A NEW COMPLEX HYPOTENSIVE DRUG COMBINATION].
Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Cerebrovascular Disorders; Coronary Disease; | 1963 |
ANGIOTENSIN SKIN TEST IN NORMOTENSIVE SUBJECTS AND THE EFFECT OF SOME ANTIHYPERTENSIVE DRUGS ON THE TEST.
Topics: Angiotensins; Antihypertensive Agents; Blood Pressure; Guanethidine; Humans; Hydralazine; Hypertensi | 1963 |
[CLINICAL RESEARCH WITH A COMPOUND HYPOTENSIVE PREPARATION (MEBUTAMATE + 1-4 DIHYDRAZINOPHTHALAZINE + DIHYDROCHLOROTHIAZIDE + POTASSIUM)].
Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Humans; Hydralazine; Hydrochlorothiazide; Hyp | 1963 |
[DRUG THERAPY OF HIGH BLOOD PRESSURE IN THE PAST, PRESENT AND FUTURE].
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hyperten | 1963 |
[TREATMENT OF ESSENTIAL HYPERTENSION].
Topics: Antihypertensive Agents; Diuretics; Essential Hypertension; Hydralazine; Hypertension; Reserpine | 1963 |
[HYPERTENSION].
Topics: Cerebral Hemorrhage; Diuretics; Ganglionic Blockers; Heart Arrest; Hydralazine; Hypertension; Kidney | 1963 |
THE HYPERGLYCEMIC EFFECT OF HYPOTENSIVE DRUGS.
Topics: Antihypertensive Agents; Benzothiadiazines; Black People; Blood Glucose; Diazoxide; Guanethidine; Hu | 1964 |
HYDRALAZINE IN HYPERTENSION.
Topics: Chlorthalidone; Humans; Hydralazine; Hypertension; Reserpine | 1964 |
ACUTE GLOMERULONEPHRITIS.
Topics: Blood Chemical Analysis; Child; Convalescence; Edema; Electrocardiography; Erythromycin; Glomerulone | 1964 |
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine; | 1964 |
[THE MEDICAL TREATMENT OF HYPERTENSION].
Topics: Alkaloids; Antihypertensive Agents; Diuretics; Ganglionic Blockers; Guanethidine; Hydralazine; Hyper | 1964 |
HYPERALDOSTERONISM AND RENAL SODIUM LOSS REVERSED BY DRUG TREATMENT FOR MALIGNANT HYPERTENSION.
Topics: Blood Chemical Analysis; Chlorambucil; Guanethidine; Humans; Hydralazine; Hyperaldosteronism; Hypert | 1964 |
DISSEMINATED LUPUS ERYTHEMATOSUS IN A 28-MONTH-OLD INFANT WITH ONSET DURING HYDRALAZINE THERAPY.
Topics: Blood Transfusion; Cerebral Palsy; Child; Diseases in Twins; Erythroblastosis, Fetal; Fetus; Hydrala | 1964 |
GUANETHIDINE IN COMBINATION WITH HYDRALAZINE AND WITH HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Blood Pressure Determination; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Toxicolo | 1964 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine | 1964 |
[MEDICAL TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Diuretics; Ganglionic Blockers; Hydralazine; Hypertension; Methyldopa; Phar | 1964 |
[CONSIDERATIONS ON THE RENAL SIDE-EFFECTS DURING TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Bretylium Compounds; Chlorothiazide; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; K | 1964 |
[CURRENT POSSIBILITIES OF AMBULATORY TREATMENT IN ARTERIAL HYPERTENSION].
Topics: Benzothiadiazines; Diuretics; Humans; Hydralazine; Hypertension; Reserpine | 1964 |
COMPARISON OF ALPHA-METHYLDOPA WITH STANDARD ANTIHYPERTENSIVE THERAPY IN MAN.
Topics: Antihypertensive Agents; Blood Pressure Determination; Guanethidine; Humans; Hydralazine; Hydrochlor | 1964 |
DRUG THERAPY OF HYPERTENSION.
Topics: Alkaloids; Antihypertensive Agents; Chlorothiazide; Diuretics; Ganglionic Blockers; Guanethidine; Hy | 1964 |
THE CONTINUING PROBLEM OF ECLAMPSIA.
Topics: Amobarbital; Antihypertensive Agents; Cesarean Section; Eclampsia; Female; Humans; Hydralazine; Hype | 1964 |
LONG TERM THERAPY WITH GUANETHIDINE AND ASSOCIATED ANTIHYPERTENSIVE DRUGS.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reser | 1964 |
[MEDICAL TREATMENT OF HYPERTENSION].
Topics: Antihypertensive Agents; Bretylium Compounds; Diuretics; Ganglionic Blockers; Guanethidine; Hydralaz | 1964 |
[MEDICAL TREATMENT OF HYPERTENSIVE CRISES].
Topics: Diuretics; Female; Ganglionic Blockers; Glomerulonephritis; Hexamethonium Compounds; Humans; Hydrala | 1964 |
THE EPHEDRINE RESPONSE TEST.
Topics: Alkaloids; Biomedical Research; Blood Pressure; Chlorothiazide; Ephedrine; Humans; Hydralazine; Hype | 1964 |
[TREATMENT OF HYPERTENSION DUE TO ACUTE GLOMERULONEPHRITIS WITH PARENTERAL RESERPINE AND HYDRALAZINE].
Topics: Glomerulonephritis; Hydralazine; Hypertension; Hypertension, Renal; Infusions, Parenteral; Kidney; R | 1964 |
COMBINATION DRUG THERAPY OF HYPERTENSION.
Topics: Drug Therapy; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Res | 1964 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
USE OF SER-AP-ES FOR HYPERTENSION.
Topics: Biomedical Research; Drug Therapy; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1964 |
THE HEART AND ACUTE GLOMERULONEPHRITIS.
Topics: Child; Diet, Sodium-Restricted; Digitalis Glycosides; Drug Therapy; Glomerulonephritis; Heart Diseas | 1964 |
CESAREAN SECTION IN THE ECLAMPTIC PATIENT ON ANTIHYPERTENSIVE THERAPY: A REVIEW OF FOURTEEN CASES.
Topics: Adolescent; Anesthesia; Antihypertensive Agents; Cesarean Section; Child; Drug Therapy; Eclampsia; F | 1964 |
RECENT TRENDS IN THE MEDICAL TREATMENT OF HYPERTENSION.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Hydralazine; Hypertension; Mecamylamine; Methyldop | 1964 |
THE EVALUATION OF ANTIHYPERTENSIVE THERAPY COOPERATIVE CLINICAL TRIAL METHOD. I. DOUBLE-BLIND CONTROL COMPARISON OF CHLOROTHIAZIDE, RAUWOLFIA SERPENTINA, AND HYDRALAZINE.
Topics: Antihypertensive Agents; Biomedical Research; Chlorothiazide; Double-Blind Method; Drug Therapy; Hea | 1964 |
[HYDRALAZINE SYNDROME IN THE LIGHT OF A CASE].
Topics: Blood Protein Disorders; Exudates and Transudates; Fever; Humans; Hydralazine; Hypertension; Pericar | 1964 |
LUPUS DIATHESIS AND THE HYDRALAZINE SYNDROME.
Topics: Disease Susceptibility; Drug Therapy; Genetics, Medical; Hydralazine; Hypertension; Lupus Erythemato | 1965 |
[CLINICAL EVALUATION OF A PHARMACOLOGIC ASSOCIATION WITH HYPOTENSIVE ACTION].
Topics: Antihypertensive Agents; Biomedical Research; Carbamates; Drug Therapy; Electric Impedance; Humans; | 1964 |
HEMODYNAMIC RESPONSE TO ANTIHYPERTENSIVE DRUG THERAPY.
Topics: Antihypertensive Agents; Blood Circulation; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dru | 1965 |
[THE PRESENT PLACE OF RAUWOLFIA AND HYDRALAZINE DERIVATIVES IN THE TREATMENT OF HYPERTENSION].
Topics: Antihypertensive Agents; Drug Therapy; Hydralazine; Hypertension; Rauwolfia | 1965 |
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulo | 1965 |
[UNUSUAL COURSE OF THE HYDRALAZINE SYNDROME].
Topics: Drug Therapy; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Toxicology | 1965 |
HEREDITARY SPHEROCYTOSIS AND POLYCYTHEMIA.
Topics: Ankyrins; Bloodletting; Chlorothiazide; Drug Therapy; Geriatrics; Humans; Hydralazine; Hypertension; | 1965 |
LUPUS DIATHESIS.
Topics: Allergy and Immunology; Disease Susceptibility; Drug Hypersensitivity; Humans; Hydralazine; Hyperten | 1965 |
The hydralazine syndrome.
Topics: Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Rheumatic Diseases; Sympatholytics | 1955 |
[Effects of hydralazine on renal circulation in arterial hypertension].
Topics: Cardiovascular System; Hydralazine; Hypertension; Kidney; Renal Circulation; Sympatholytics | 1955 |
Hydralazine in nephritic and normal children with renal hemodynamic studies.
Topics: Child; Hemodynamics; Hydralazine; Hypertension; Infant; Nephritis; Sympatholytics | 1955 |
[Ganglion-blocking agents, hydrazinophthalazines and active principles of Rauwolfia serpentina in the treatment of arterial hypertension].
Topics: Antihypertensive Agents; Autonomic Agents; Ganglionic Blockers; Hydralazine; Hypertension; Rauwolfia | 1955 |
Hexamethonium, hydralazine and rauwolfia serpentina therapy in hypertension.
Topics: Antihypertensive Agents; Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Rel | 1955 |
The effects of 1-hydrazinophthalazine upon coronary hemodynamics and myocardial oxygen metabolism in essential hypertension.
Topics: Coronary Vessels; Essential Hypertension; Heart; Hemodynamics; Humans; Hydralazine; Hypertension; My | 1955 |
[Combination of hexamethonium and hydrazinophthalazine in the treatment of arterial hypertension].
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central; Sympatho | 1954 |
[Modern hypotensors in daily clinical practice (hydralazine, Rauwolfia serpentina and Veratrum viride); concerning 50 cases].
Topics: Antihypertensive Agents; Hydralazine; Hypertension; Rauwolfia; Secologanin Tryptamine Alkaloids; Sym | 1955 |
Acute systemic lupus erythematosus syndrome from hydralazine hydrochloride.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Sympatholytics; Syndrome | 1955 |
Cardiovascular and renal responses to the combination of hexamethonium and 1-hydrazinophthalazine (apresoline) in hypertensive subjects.
Topics: Cardiovascular System; Hexamethonium; Hydralazine; Hypertension; Kidney; Muscle Relaxants, Central; | 1955 |
1-Hydrazinophthalazine (apresoline) toxicity; report of a case of arthritis of the rheumatoid type and pancytopenia.
Topics: Anemia; Anemia, Aplastic; Arthritis; Arthritis, Rheumatoid; Hydralazine; Hypertension; Pancytopenia; | 1955 |
The use of pentolinium tartrate with and without hydralazine in the treatment of severe hypertension.
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Pentolinium Tartrate; S | 1955 |
[1-Hydrazinophthalazine (Apresoline) in arterial hypertension].
Topics: Hydralazine; Hypertension; Sympatholytics | 1955 |
[Treatment of arterial hypertension with l-hydrazinophthalazine (apresoline)].
Topics: Hydralazine; Hypertension; Sympatholytics | 1955 |
Evaluation of drug therapy of hypertension; experience with ansolysen, hexamethonium, apresoline, and reserpine.
Topics: Drug Therapy; Hexamethonium; Hydralazine; Hypertension; Pentolinium Tartrate; Reserpine | 1955 |
[Contribution to the treatment of arterial hypertension. Our experiences with adelphan].
Topics: Humans; Hydralazine; Hypertension; Reserpine | 1959 |
Abnormalities of circulating cells and proteins in hydralazine-treated patients without toxic symptoms.
Topics: Blood Circulation; Blood Proteins; Hemoglobins; Humans; Hydralazine; Hypertension | 1962 |
Pharmacology and clinical use of hydralazine in the treatment of diastolic hypertension.
Topics: Autonomic Nervous System Diseases; Humans; Hydralazine; Hypertension | 1962 |
Contribution of blood pressure variability to the effect of nitrendipine on end-organ damage in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Hydralazine; Hy | 2003 |
Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
Topics: Amides; Animals; Blood Pressure; Enzyme Inhibitors; Hydralazine; Hypertension; Injections; Intracell | 2004 |
Hydralazine as antihypertensive therapy in obesity-related hypertension.
Topics: Animals; Antihypertensive Agents; Biometry; Blood Pressure; Cardiomegaly; Female; Heart Rate; Hormon | 2004 |
Control of hypertension by hexamethonium and 1-hydrazinophthalazine; preliminary observations.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
Clinical evaluation of 1-hydrazinophthalazine (C-5968) in hypertension, with special reference to alternating treatment with hexamethonium.
Topics: Cardiovascular Agents; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
NEW approved drugs: hexamethonium bromide; hydralazine hydrochloride.
Topics: Drug Approval; Hexamethonium; Hydralazine; Hypertension; Muscle Relaxants, Central | 1952 |
Effects of tempol on renal angiotensinogen production in Dahl salt-sensitive rats.
Topics: Actins; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Cyclic | 2004 |
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Body Weight; Collagen; Endothelium, Vascular | 2004 |
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Collagen | 2004 |
Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; | 2004 |
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Wester | 2004 |
Gene expression in uremic left ventricular hypertrophy: effects of hypertension and anemia.
Topics: Actins; Anemia; Animals; Atrial Natriuretic Factor; Erythropoietin; Gene Expression; Heart Ventricle | 2004 |
Olmesartan improves endothelin-induced hypertension and oxidative stress in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; En | 2004 |
The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blotting, Western; Disease Mode | 2004 |
Control of oxidative stress in microcirculation of spontaneously hypertensive rats.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Blood Pressure; Endothelium, Lymphatic; Free Radicals; Hydra | 2005 |
Medicine. Race and reification in science.
Topics: Bias; Cardiovascular Agents; Crime; Databases, Nucleic Acid; Drug Combinations; Forensic Sciences; G | 2005 |
Inhibition of NF-kappaB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomegaly; Disease | 2005 |
Isosorbide dinitrate and hydralazine in blacks with heart failure.
Topics: Black People; Coronary Disease; Drug Therapy, Combination; Heart Failure; Humans; Hydralazine; Hyper | 2005 |
Isosorbide dinitrate and hydralazine in blacks with heart failure.
Topics: Black People; Calcium Channel Blockers; Drug Therapy, Combination; Heart Failure; Humans; Hydralazin | 2005 |
Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Enzyme Activation; Female; Hear | 2005 |
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; | 2005 |
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats.
Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Fe | 2005 |
Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; C | 2005 |
Report from the Cardiovascular and Renal Drugs Advisory Committee: US Food and Drug Administration; June 15-16, 2005; Gaithersburg, Md.
Topics: Antihypertensive Agents; Black People; Cardiovascular Agents; Drug Combinations; Drug Labeling; Epid | 2005 |
Blockade of angiotensin II provides additional benefits in hypertension- and ageing-related cardiac and vascular dysfunctions beyond its blood pressure-lowering effects.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; B | 2005 |
Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor system following blood pressure reduction in nitric oxide-deficient hypertension.
Topics: Adrenomedullin; Animals; Body Weight; Hydralazine; Hydrochlorothiazide; Hypertension; Intracellular | 2006 |
Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; An | 2006 |
Impact of antihypertensive treatments on erectile responses in aging spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Enalapril; Hydralazine; Hydroc | 2006 |
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker.
Topics: Animals; Apoptosis; Biomarkers; Blood Pressure; Eplerenone; Fibrosis; Glomerulosclerosis, Focal Segm | 2006 |
ACE inhibition restores the vasodilator potency of the endothelium-derived relaxing factor, L-S-nitrosocysteine, in conscious Spontaneously Hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; | 2006 |
Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl | 2006 |
Effects of angiotensin II type 1 receptor blockade on the systemic blood nitric oxide dynamics in Nomega-nitro-L-arginine methyl ester-treated rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Body Weig | 2006 |
Increased intracavernosal pressure response in hypertensive rats after chronic hemin treatment.
Topics: Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug | 2006 |
p38 MAP kinase activity is correlated with angiotensin II type 1 receptor blocker-induced left ventricular reverse remodeling in spontaneously hypertensive heart failure rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cardiomegaly; Female; Heart Failure; Hydralazine; | 2006 |
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Cardiomegaly; Dihydropyridines; Endomyocardial Fibros | 2006 |
Transient AT1 receptor-inhibition in prehypertensive spontaneously hypertensive rats results in maintained cardiac protection until advanced age.
Topics: Age Factors; Aging; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; C | 2007 |
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihype | 2006 |
Transient improvement of hypertension-induced chronic renal failure with mycophenolate mofetil treatment.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; | 2006 |
Time course of vascular arginase expression and activity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arginase; Arginine; Blood Pressure; Body Weight; | 2007 |
Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Diabetic Retinopathy; Drug C | 2007 |
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates ACE and AT1 receptor gene expression and signaling: role in cardiac hypertrophy.
Topics: Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic GMP; Fibrosis; Gene Expression Regulation; | 2007 |
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cardiomegaly; Cardiotonic | 2007 |
Angiotensin II type 1 receptor blocker reduces monocyte adhesion to endothelial cells in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen | 2007 |
Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug The | 2007 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiome | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihyp | 2007 |
Sustained hypertension increases the density of AMPA receptor subunit, GluR1, in baroreceptive regions of the nucleus tractus solitarii of the rat.
Topics: Animals; Baroreflex; Dendritic Spines; Down-Regulation; Glutamic Acid; Hydralazine; Hypertension; Ma | 2008 |
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Blood Pressure | 2008 |
Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Ther | 2008 |
Persistent hypertension and progressive renal injury induced by salt overload after short term nitric oxide inhibition.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease Models, Animal; D | 2007 |
Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcineurin; Desoxycorticosterone; Echocardiograph | 2008 |
Hypertension impairs postnatal vasculogenesis: role of antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Cells; Cell Differentiation; Disease M | 2008 |
Hypertensive vascular disease. The long term effect of rapid repeated reductions of arterial pressure with diazoxide.
Topics: Adult; Chlorthalidone; Diazoxide; Female; Heart Failure; Humans; Hydralazine; Hypertension; Injectio | 1967 |
[Pathogenesis and therapy of essential arterial hypertension. Clinical case].
Topics: Adult; Aged; Analgesics; Blood Pressure Determination; Chlorothiazide; Chlorpromazine; Female; Guane | 1967 |
[Contribution to anti-hypertensive therapy with a drug combination].
Topics: Aged; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; | 1967 |
Sodium nitroprusside and other reserve drugs for hypertensive emergencies.
Topics: Animals; Diazoxide; Dogs; Ferricyanides; Humans; Hydralazine; Hypertension | 1967 |
The epidemiology of drug-induced systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; | 1967 |
Potentials and limitations of angiotensin converting enzyme inhibition in the treatment of hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Clonidine; | 1984 |
Combined prazosin and hydralazine in resistant hypertension.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; M | 1980 |
Current trends in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertension; | 1980 |
Adverse drug reactions to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Human | 1980 |
Drugs and the heart. VI. Vasodilating drugs.
Topics: Cardiotonic Agents; Chronic Disease; Heart Failure; Hemodynamics; Humans; Hydralazine; Hypertension; | 1980 |
What patients with hypertension should know about their medication.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hyp | 1980 |
Obstructive jaundice, pancytophenia and hydralazine.
Topics: Cholestasis; Humans; Hydralazine; Hypertension; Male; Middle Aged; Pancytopenia | 1981 |
Content and turnover of noradrenaline in spinal cord and cerebellum of spontaneously hypertensive and stroke-prone rats.
Topics: Animals; Blood Pressure; Cerebellum; Cerebrovascular Disorders; Female; Hydralazine; Hypertension; M | 1981 |
Differential effects of diuresis and beta-adrenoreceptor blockade during angiotensin-converting enzyme inhibition in patients with severe hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; | 1982 |
HDL cholesterol and beta-adrenoceptor blocking agents in a 5 year multifactorial primary prevention trial.
Topics: Adrenergic beta-Antagonists; Cholesterol; Cholesterol, HDL; Coronary Disease; Diuretics; Humans; Hyd | 1982 |
[Antihypertensive therapy in pregnancy].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydro | 1982 |
Treatment of hypertension at an outpatient hypertension clinic. Blood pressure control, dropout rate, and side effects.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Diuretics; | 1982 |
Rapidly progressive glomerulonephritis after hydralazine.
Topics: Glomerulonephritis; Humans; Hydralazine; Hypertension | 1983 |
Adrenergic beta-receptor blockers in hypertension of pregnancy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Birth Weight; Blood Pressure; Delivery, Obstetric; F | 1982 |
Office management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Capt | 1984 |
Drug selection in the treatment of pregnancy hypertension. A survey.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Card | 1984 |
Clinical trials of adrenergic antagonists in pregnancy hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growt | 1984 |
Hypertension: special concerns in geriatric patients.
Topics: Adrenergic beta-Antagonists; Aged; Aging; Calcium Channel Blockers; Captopril; Diet, Sodium-Restrict | 1984 |
Autonomic dysreflexia (hyperreflexia).
Topics: Antihypertensive Agents; Autonomic Nervous System; Autonomic Nervous System Diseases; Ganglionic Blo | 1984 |
Survival of treated hypertensive patients as a function of compliance and control.
Topics: Blood Pressure Determination; Female; Follow-Up Studies; Ganglionic Blockers; Humans; Hydralazine; H | 1984 |
Neuropsychiatric manifestations of antihypertensive medications.
Topics: Adrenergic beta-Antagonists; Affective Symptoms; Antihypertensive Agents; Benzothiadiazines; Clonidi | 1983 |
Effect of beta-receptor-blocking agents on cardiovascular structural changes in spontaneous and noradrenaline-induced hypertension in rats.
Topics: Animals; Aorta; Atenolol; Heart Ventricles; Hydralazine; Hypertension; Male; Norepinephrine; Organ S | 1980 |
Therapeutic regime on pregnancy induced hypertension.
Topics: Dextrans; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydralazine; Hypertension; I | 1982 |
Independence of blood pressure and locomotor hyperactivity in normotensive and genetically hypertensive rat.
Topics: Animals; Blood Pressure; Hot Temperature; Humans; Hydralazine; Hyperkinesis; Hypertension; Hypertens | 1983 |
Hydralazine and lupus nephritis.
Topics: Adult; Aged; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Immune Complex Diseases; | 1984 |
Myocardial function structure and collagen in the spontaneously hypertensive rat: progression from compensated hypertrophy to haemodynamic impairment.
Topics: Animals; Body Weight; Cardiomegaly; Collagen; Guanethidine; Heart Failure; Hydralazine; Hypertension | 1984 |
Inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitiv | 1980 |
[Vasodilating agents in the treatment of hypertension - a review].
Topics: Diazoxide; Humans; Hydralazine; Hypertension; Minoxidil; Nitroprusside; Prazosin; Synaptic Transmiss | 1981 |
Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Comb | 1981 |
[Forum on hypertension. Part 8. Hypertension management in pregnancy].
Topics: Antihypertensive Agents; Dihydralazine; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyl | 1981 |
Comparative effects of alpha-methyldopa, propranolol and hydralazine therapy on cardiac adenylate cyclase activity in normal and spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Glucagon; Hydralazine; Hypertension; Male; Meth | 1981 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; | 1982 |
Regression of myocardial hypertrophy and influence of adrenergic system.
Topics: Animals; Blood Pressure; Cardiomegaly; Catecholamines; Dose-Response Relationship, Drug; Hydralazine | 1983 |
Characterization of the vasodilator action of antihypertensive drug budralazine.
Topics: Anesthesia; Animals; Antihypertensive Agents; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Dogs; Ear, Ex | 1983 |
Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Blood Vessels; Captopril; Dihydralazine; Heart; Hydralazine; Hypertension; | 1983 |
Renal vein renin sampling in essential hypertension using hydralazine and the tourniquet test.
Topics: Blood Volume; Humans; Hydralazine; Hypertension; Kidney; Renal Veins; Renin; Tourniquets | 1984 |
Comparative effects of hydralazine and captopril on the cardiovascular changes in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Body Weight; Captopril; Cardiovascular System; Endothelium; Heart Ve | 1984 |
Systemic and cardiac haemodynamic interactions between guanfacine and hydrallazine in hypertensive patients.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Guanfacine; Guanidines; Hemodynamics; Humans; Hydral | 1984 |
[Docidrazin. Long-term observation with a 3-component antihypertensive agent].
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Drug Combinations; Female; Humans; Hydral | 1983 |
Long term propranolol and hydralazine in hypertension.
Topics: Adult; Drug Combinations; Humans; Hydralazine; Hypertension; Long-Term Care; Propranolol | 1984 |
Lack of inhibition of diamine oxidase during hydralazine therapy.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Humans; Hydralazine; Hypertension; Male; Putrescine; | 1984 |
Effect of antihypertensive therapy on calcium transport by cardiac sarcoplasmic reticulum of SHRs.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Cardiomegaly; Hydralazine; Hypert | 1980 |
Renal failure, dyspnea and anemia in a 57 year old woman. Clinicopathologic conference.
Topics: Anemia; Diagnosis, Differential; Dyspnea; Female; Glomerulonephritis; Humans; Hydralazine; Hypertens | 1981 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; Clonidine; Heart; Hemodynamics; Hydralazine; Hypertension; Methyldopa; Organ | 1982 |
[Hemodynamic response to hydralazine in pregnant women with hypertension].
Topics: Female; Hemodynamics; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complic | 1984 |
Renal phosphate excretion in spontaneously hypertensive and normotensive Wistar Kyoto rats.
Topics: Animals; Blood Pressure; Calcium; Female; Hydralazine; Hypertension; Kidney Tubules; Magnesium; Male | 1984 |
Pharmacological characterization of apomorphine-induced hypothermia in the spontaneously hypertensive rat.
Topics: Animals; Apomorphine; Blood Pressure; Body Temperature; Haloperidol; Hydralazine; Hypertension; Hypo | 1984 |
Differential influence of the calcium antagonist nitrendipine and the vasodilator hydralazine on normal and elevated blood pressure.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hydralazine; Hypertension; Nifedipine | 1984 |
Effect of oral dose size on hydralazine kinetics and vasodepressor response.
Topics: Acetylation; Administration, Oral; Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; He | 1984 |
Slow-release metoprolol, hydrochlorothiazide and hydralazine in stepwise treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Fo | 1984 |
Hydralazine-induced lupus syndrome.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Prednisone | 1984 |
Efficacy of combination of propranolol and hydralazine versus alpha-methyldopa in hypertension.
Topics: Adult; Aged; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; | 1984 |
Increased adrenal epinephrine and norepinephrine in spontaneously hypertensive rats treated with hyperbaric oxygen.
Topics: Adrenal Glands; Animals; Epinephrine; Hydralazine; Hyperbaric Oxygenation; Hypertension; Male; Norep | 1984 |
Cerebrovascular effects of dihydralazine in hypertensive and normotensive rats.
Topics: Animals; Arteries; Blood Pressure; Cerebrovascular Circulation; Dihydralazine; Female; Homeostasis; | 1983 |
Disposition of the adrenergic blocker metoprolol in the late-pregnant woman, the amniotic fluid, the cord blood and the neonate.
Topics: Amniotic Fluid; Drug Therapy, Combination; Female; Fetal Blood; Humans; Hydralazine; Hypertension; I | 1984 |
Drinking water and drug dosage in rat studies.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Bepridil; Blood Pressure; Dose-Response Re | 1983 |
[Myocardial 201-thallium uptake after hydralazine in coronary disease].
Topics: Coronary Circulation; Coronary Disease; Humans; Hydralazine; Hypertension; Male; Myocardium; Radiois | 1983 |
Serum uric acid in mild essential hypertension.
Topics: Adult; Aged; Combined Modality Therapy; Diet, Sodium-Restricted; Diuretics; Female; Humans; Hydralaz | 1983 |
Hypotensive and diuretic actions of diltiazem in spontaneously hypertensive and Wistar Kyoto rats.
Topics: Animals; Benzazepines; Blood Pressure; Diltiazem; Diuresis; Heart Rate; Hydralazine; Hypertension; M | 1983 |
Arterial pressure-urinary output relationship in DOCA-saline hypertensive rats.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Heart Rate; Hydralazine; Hypertension; Kidney; Male; | 1983 |
Acute effect of dihydralazine on uteroplacental blood flow in hypertension during pregnancy.
Topics: Blood Pressure; Dihydralazine; Female; Heart Rate; Humans; Hydralazine; Hypertension; Placenta; Pre- | 1983 |
Pharmacokinetics of oral hydralazine in chronic heart failure.
Topics: Administration, Oral; Aged; Female; Heart Failure; Humans; Hydralazine; Hypertension; Kinetics; Male | 1983 |
Hemodynamic effects of the arteriolar vasodilators hydralazine, dihydralazine and endralazine in the conscious spontaneously hypertensive rat.
Topics: Animals; Denervation; Dihydralazine; Hemodynamics; Hydralazine; Hypertension; Male; Pressoreceptors; | 1983 |
Effective treatment of refractory hypertension by combination of direct vasodilators.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; M | 1983 |
Electroconvulsive therapy and intracranial aneurysm. Prevention of blood pressure elevation in a normotensive patient by hydralazine and propranolol.
Topics: Adult; Anesthesia, Intravenous; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Hydr | 1983 |
[Long-term treatment of arterial hypertension with a new combined preparation obsilazin].
Topics: Blood Pressure; Dihydralazine; Drug Combinations; Humans; Hydralazine; Hypertension; Propranolol; Pr | 1983 |
[Causes of acute valve-conditioned left ventricular insufficiency-- attempt at a tabulated review].
Topics: Aortic Valve Insufficiency; Cardiac Glycosides; Dyspnea; Endocarditis, Bacterial; Humans; Hydralazin | 1984 |
The Parkland Memorial Hospital protocol for treatment of eclampsia: evaluation of 245 cases.
Topics: Analgesics; Anesthetics; Delivery, Obstetric; Eclampsia; Female; Fetal Death; Fluid Therapy; Humans; | 1984 |
Cortical blindness as a complication of eclampsia.
Topics: Adult; Blindness; Eclampsia; Female; Humans; Hydralazine; Hypertension; Labor, Induced; Oxytocin; Pr | 1984 |
Hemodynamic modification of aortic atherosclerosis. Effects of propranolol vs hydralazine in hypertensive hyperlipidemic rabbits.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Cholesterol; Hemodynamics; Hydralazine; Hyperlipidemias; | 1984 |
Should the acetylator phenotype be determined when prescribing hydralazine for hypertension?
Topics: Acetylation; Adult; Aged; Blood Pressure; Chemistry, Organic; Female; Humans; Hydralazine; Hypertens | 1984 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disea | 1984 |
Effect of food on blood hydralazine levels and response in hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chromatography, High Pressure Liquid; Female; Foo | 1984 |
[Use of adelphan-esidrex with hypertension patients].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Electrocardiography; Femal | 1984 |
Intrapartum treatment of preeclamptic hypertension by ketanserin--a serotonin receptor antagonist.
Topics: Adult; Antihypertensive Agents; Delivery, Obstetric; Female; Humans; Hydralazine; Hypertension; Infa | 1984 |
Focal glomerulonephritis in the course of hydralazine-induced lupus syndrome.
Topics: Biopsy; Glomerulonephritis; Humans; Hydralazine; Hypertension; Kidney; Lupus Erythematosus, Systemic | 1984 |
Vasodilators in the treatment of hypertension.
Topics: Calcium Channel Blockers; Captopril; Diazoxide; Humans; Hydralazine; Hypertension; Minoxidil; Nitrop | 1982 |
Hydralazine, antinuclear antibodies, and the lupus syndrome.
Topics: Acetylation; Antibodies, Antinuclear; Dose-Response Relationship, Drug; Female; Humans; Hydralazine; | 1982 |
[Comparative hemodynamic effects of 2 vasodilators: dihydralazine and diltiazem in permanent essential arterial hypertension].
Topics: Adult; Arteries; Arterioles; Benzazepines; Blood Pressure; Dihydralazine; Diltiazem; Heart Rate; Hem | 1982 |
Baroreflex response and vasodilating drugs in essential hypertension.
Topics: Adult; Benzazepines; Blood Pressure; Brachial Artery; Dihydralazine; Diltiazem; Heart Rate; Humans; | 1983 |
Shock after phenothiazine administration in a pregnant patient with a pheochromocytoma. A case report and literature review.
Topics: Adrenal Gland Neoplasms; Adult; Diagnosis, Differential; Female; Humans; Hydralazine; Hypertension; | 1983 |
Hypotensive action of verapamil in a group of hydralazine-dependent hypertensive patients.
Topics: Adult; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Hydralazine; Hypertension; M | 1983 |
Antihypertensive effect of diltiazem in young or adult rats of genetically hypertensive strains.
Topics: Age Factors; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Diltiazem; Dose-Response R | 1983 |
Antihypertensive therapy during pregnancy.
Topics: Antihypertensive Agents; Diuretics; Female; Humans; Hydralazine; Hypertension; Methyldopa; Pregnancy | 1983 |
[Hemodynamic indicators, phase structure of the systole of the left and right heart ventricles and the state of pulmonary circulation and microcirculation in patients with hypertension treated with adelphane-esindex].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Heart Ventricles; Hemodynamics; Hum | 1983 |
Baroreflex sensitivity as a determinant of responses to hydralazine in dogs.
Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Hydralazine; Hypertension; Male; Pressoreceptors; | 1983 |
Severe consequence of hypertension in pregnancy.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pr | 1983 |
Efficacy and tolerability of hydralazine, in conventional and slow-release preparations, during long-term treatment of primary hypertension.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Drug Administration Schedule; Drug Evaluation; D | 1983 |
Hydralazine-phenobarbital interactions in rats. II. Disposition of hydralazine and its acid-labile conjugates, and liver drug-metabolizing enzyme activities in normotensive and spontaneously hypertensive rats.
Topics: Animals; Drug Interactions; Hydralazine; Hypertension; Liver; Male; Phenobarbital; Rats; Rats, Inbre | 1983 |
[Changes in the hemodynamic indices of hypertension patients].
Topics: Adult; Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Drug Evaluation; Female; H | 1983 |
Differences in transmission through the dorsal column nuclei in spontaneously hypertensive and Wistar Kyoto rats.
Topics: Animals; Brain; Electroshock; Evoked Potentials; Hydralazine; Hypertension; Male; Rats; Rats, Inbred | 1983 |
Dihydralazine hepatitis: report of a case and review of the literature.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Dihydralazine; Hepatic Encephalopathy; Humans; Hydra | 1983 |
Treatment of hypertension associated with head injury.
Topics: Adolescent; Adult; Craniocerebral Trauma; Epinephrine; Hemodynamics; Humans; Hydralazine; Hypertensi | 1983 |
Medical treatment of hypertension and renal failure in scleroderma.
Topics: Acute Kidney Injury; Adult; Female; Humans; Hydralazine; Hypertension; Minoxidil; Propranolol; Scler | 1981 |
Hydralazine in chronic CHF.
Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com | 1981 |
Prospective study of immune response to hydralazine and development of antideoxyribonucleoprotein in patients receiving hydralazine.
Topics: Antibodies; Antibodies, Antinuclear; Antibody Formation; Deoxyribonucleoproteins; DNA; Humans; Hydra | 1980 |
Hydrallazine in hypertension: is there a safe dose?
Topics: Adult; Antibodies; Antibodies, Antinuclear; DNA; Female; Humans; Hydralazine; Hypertension; Lupus Er | 1980 |
Prospective study of immunologic effects of hydralazine in hypertensive patients.
Topics: Acetylation; Adolescent; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Female; Humans; Hydral | 1981 |
Immunologic effects of hydralazine in hypertensive patients.
Topics: Acetylation; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Binding Sites, Antibody; Coombs Te | 1981 |
Captopril in severe treatment-resistant hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Female; Furosemide; Heart Rate; Humans; Hydralaz | 1980 |
Effect of neonatal sympathectomy with 6-hydroxydopamine on reactivity of the renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Female; Hydralazine; Hydroxy | 1980 |
[Captopril in treatment-resistant hypertension (author's transl)].
Topics: Adult; Captopril; Diastole; Drug Combinations; Female; Furosemide; Humans; Hydralazine; Hydrochlorot | 1980 |
Long-term effects of captopril on cellular sodium content and mechanical properties of aortic smooth muscle from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Captopril; Hydralazine; Hypertension; In Vitro Techniques; | 1981 |
Exaggerated salt appetite of spontaneously hypertensive rats is decreased by central angiotensin-converting enzyme blockade.
Topics: Angiotensin II; Animals; Appetite; Brain; Captopril; Hydralazine; Hypertension; Injections, Intraven | 1982 |
The addition of prazosin to standard triple therapy in the treatment of severe hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Therapy, Combination; Electrocardiography; Fe | 1982 |
The hypotensive response to hydralazine, in triple therapy, is not related to acetylator phenotype.
Topics: Acetylation; Blood Pressure; Humans; Hydralazine; Hypertension; Phenotype | 1982 |
[Significance & treatment of abnormal blood viscosities in pre-eclamptic patients (author's transl)].
Topics: Adenosine Triphosphate; Adult; Blood Viscosity; Blood Volume Determination; Erythrocyte Count; Femal | 1982 |
Endogenous generation of hydralazine from labile hydralazine hydrazones.
Topics: Animals; Biotransformation; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrazone | 1982 |
Step-care approach to improving hypertensive patient compliance.
Topics: Benzothiadiazines; Body Weight; Diet, Sodium-Restricted; Diuretics; Family; Hospitalization; Humans; | 1982 |
[Changes In myocardial contractile function and microcirculation in hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Conjunctiva; Drug Combinations; Dru | 1982 |
The effect of low-dose dihydrallazine on the fetus in the emergency treatment of hypertension in pregnancy.
Topics: Blood Pressure; Depression, Chemical; Dihydralazine; Female; Fetal Growth Retardation; Fetal Heart; | 1982 |
Arterial muscle membrane abnormalities of hydralazine-treated spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Cell Membrane; Hydralazine; Hypertension; In Vitro Techniques; Me | 1982 |
Effects of antihypertensive agents on blood velocity: implications for atherogenesis.
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Flow Velocity; Blood Pressure; Female; | 1982 |
[More on the comparison of minoxidil with dihydralazine].
Topics: Dihydralazine; Humans; Hydralazine; Hypertension; Minoxidil; Pyrimidines | 1982 |
Pharmacodynamic interaction between hydralazine and phenobarbital in normotensive and spontaneously hypertensive rats.
Topics: Animals; Drug Interactions; Hydralazine; Hypertension; Male; Phenobarbital; Rats; Rats, Inbred Strai | 1982 |
Vascular effects of dihydralazine during prevention of genetic hypertension development in SHR rats.
Topics: Animals; Aorta; Dihydralazine; Hydralazine; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inb | 1982 |
Cerebral acting maps of hydralazine, clonidine, and alpha-methyldopa in spontaneously hypertensive rats as demonstrated by the 14C-deoxy-D-glucose method.
Topics: Animals; Blood Pressure; Brain; Clonidine; Deoxy Sugars; Deoxyglucose; Hydralazine; Hypertension; Ma | 1982 |
[Effectiveness of antihypertensive treatment with labetalol as compared with the combination of hydralazine and propranolol].
Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hyper | 1981 |
[Slow-release hydralazine in the treatment of essential arterial hypertension].
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Female; Humans; Hydralazine; Hypertension; Male; | 1982 |
Immediate central and peripheral haemodynamic effects of a new vasodilating agent Pinacidil (P1134) in hypertensive man.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Guanidines; Heart Rate; Hemodynamics; Humans; Hydrala | 1981 |
Transplacental passage and breast milk concentrations of hydralazine.
Topics: Adult; Breast Feeding; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Maternal-Fetal Ex | 1982 |
Acute low-dose hydralazine induced lupus syndrome (HILS).
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic | 1981 |
Congenital intrathoracic kidney.
Topics: Chlorothiazide; Humans; Hydralazine; Hypertension; Infant; Kidney; Male; Thorax | 1981 |
Pharmacologic approach to the management of childhood hypertension.
Topics: Antihypertensive Agents; Autonomic Nervous System; Central Nervous System; Child; Diazoxide; Humans; | 1981 |
Comparative antihypertensive effects of a diuretic, reserpine, and hydralazine in the spontaneously hypertensive rat.
Topics: Animals; Body Weight; Disease Models, Animal; Female; Furosemide; Hydralazine; Hypertension; Intesti | 1981 |
Correlation between decreased heart rate and central inhibition of sympathetic discharge after prazosin administration in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiovascular System; Heart Rate; Hydralazine; Hypertension; Male; Prazosi | 1981 |
Hydralazine-induced hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Hypertension; Liver; Liver Cirr | 1981 |
[Adelphan-esidrex in the treatment of hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Hemodynamics; Humans; Hydralazine; | 1980 |
[Regional and central hemodynamic changes during the treatment of hypertension with obsidan, apressin and their combination].
Topics: Adolescent; Adult; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrala | 1981 |
Thermoregulation in spontaneously hypertensive rats: effects of antihypertensive treatments.
Topics: Animals; Antihypertensive Agents; Body Temperature Regulation; Chlorothiazide; Clonidine; Hydralazin | 1981 |
A combination of propranolol and hydralizine for the treatment of severe hypertension.
Topics: Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Propranolol | 1981 |
Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Hypertensio | 1981 |
Possible mechanisms of the hydralazine-related lupus-like syndrome.
Topics: Anemia, Hypochromic; Anticholesteremic Agents; Blood Pressure; Diastole; Dose-Response Relationship, | 1981 |
Variability of plasma hydralazine concentrations in male hypertensive patients.
Topics: Acetylation; Aged; Biological Availability; Dose-Response Relationship, Drug; Humans; Hydralazine; H | 1981 |
[Antihypertensive activity of minoxidil, hydralazine, prazosin, phentolamine and clonidine in spontaneously hypertensive rats. Comparison with therapeutic dosages].
Topics: Animals; Antihypertensive Agents; Clonidine; Hydralazine; Hypertension; Minoxidil; Phentolamine; Pra | 1981 |
Determinants of response to intravenous hydralazine in hypertension.
Topics: Acetylation; Blood Pressure; Dose-Response Relationship, Drug; Genetic Variation; Humans; Hydralazin | 1981 |
[Phthalazine derivatives in the treatment of arterial hypertension].
Topics: Arterioles; Blood Pressure; Humans; Hydralazine; Hydrazines; Hypertension; Todralazine; Vasodilator | 1981 |
Neuropsychiatric sequelae of pharmacotherapy of cardiac arrhythmias and hypertension.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Brain; Drug Interactions; Gua | 1981 |
Renal lesions and proteinuria in the spontaneously hypertensive rat made normotensive by treatment.
Topics: Age Factors; Animals; Arteriosclerosis; Blood Pressure; Chlorothiazide; Hydralazine; Hypertension; K | 1981 |
Aortic atherosclerosis in hypertensive rabbits treated with anti-hypertensive agents having different effects on arterial flow disturbances. 1. Extent of surface involvement.
Topics: Animals; Antihypertensive Agents; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Blood | 1981 |
Propranolol and hydrallazine in the management of essential hypertension in pregnancy.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Hypoglycemia; Infant, N | 1980 |
Effect of dihydralazine on the fetus in the treatment of maternal hypertension.
Topics: Birth Weight; Dihydralazine; Female; Fetal Death; Fetal Growth Retardation; Fetal Heart; Fetal Monit | 1980 |
[Treatment of arterial hypertension. Experience with the use of a hydralazine and propranolol combination].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prop | 1980 |
Hemodynamic effects of oxdralazine and hydralazine in hypertension.
Topics: Adult; Blood Pressure; Cardiac Output; Ethanolamines; Female; Forearm; Heart Rate; Hemodynamics; Hum | 1980 |
N''-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine, monohydrate (P 1134): a new, potent vasodilator.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Dose-Response Relationship, Drug; Guanidines; Heart R | 1980 |
Special considerations in treating hypertension in the elderly.
Topics: Aged; Clonidine; Diet, Sodium-Restricted; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension | 1980 |
Hydrallazine-induced hepatitis?
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Hypertension; Liver Func | 1980 |
The metabolic and psychological effects of exercise training in hemodialysis patients.
Topics: Adult; Anemia; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Cholesterol; Female; Follow-U | 1980 |
Post carotid endarterectomy hypertension.
Topics: Aged; Brain Edema; Carotid Arteries; Endarterectomy; Female; Humans; Hydralazine; Hypertension; Intr | 1980 |
Differential effects of alpha-methyldopa, clonidine and hydralazine on norepinephrine and epinephrine synthesizing enzymes in the brainstem nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Brain Stem; Clonidine; Depression, Chemical; Dopamine beta-Hydroxyla | 1980 |
[Combined action of oxprenolol, hydrochlorothiazide and hydralazine in rats with metacorticoid induced hypertension].
Topics: Animals; Desoxycorticosterone; Drug Evaluation; Drug Therapy, Combination; Hydralazine; Hydrochlorot | 1980 |
Hydralazine-induced neonatal thrombocytopenia.
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Pre-Ec | 1980 |
[Treatment of hypertension with clofelin and adelfan-esidrex].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Dihydralazine; Drug Combinations; Drug Therap | 1980 |
Hypertension after taking hydrallazine.
Topics: Adolescent; Female; Humans; Hydralazine; Hypertension; Hypertension, Renal | 1980 |
Vasodilator drugs and resistant hypertension.
Topics: Antihypertensive Agents; Diazoxide; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Mi | 1980 |
Blood pressure response in hypertensive pregnancies treated with cortisol.
Topics: Adolescent; Adult; Blood Pressure; Drug Therapy, Combination; Ethanol; Female; Humans; Hydralazine; | 1980 |
Hydralazine prevents changes in the contractile response of aortic but not portal vein strips in hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Desoxycorticosterone; Hydralazine; Hypertension; In Vitro Techniques | 1980 |
Hydralazine kinetics in hypertensive patients after intravenous administration.
Topics: Half-Life; Humans; Hydralazine; Hypertension; Infusions, Parenteral; Kinetics; Metabolic Clearance R | 1980 |
Studies on the effect of chronic oral administration of minoxidil and hydralazine on vascular function in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Blood Pressure; Hydralazine; Hypertension; In Vitro Techniques; Male; | 1980 |
[Use of the vasodilator agent nepresol in hypertensive crisis].
Topics: Adult; Aged; Blood Pressure; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Injections, In | 1980 |
Hydralazine: mode of action at the neuroarterial junction.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hydralazine; Hypertension; In Vitro Techniques; | 1980 |
Different antihypertensive effects of nifedipine in conscious experimental hypertensive and normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Heart Rate; Hydralazine; Hyp | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydr | 1981 |
Control of hindlimb vascular resistance and vascular responsiveness in DOCA-salt hypertensive dogs.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Dogs; Female; Hindlimb; Hydralazine; Hypertension; Ma | 1981 |
Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats.
Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Data Interp | 1995 |
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Pressure control of renal renin release in Lyon hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Prediction of stroke lesions in stroke-prone spontaneously hypertensive rats by glutathione peroxidase in erythrocytes.
Topics: Animals; Antihypertensive Agents; Brain; Cerebrovascular Disorders; Diet; Disease Models, Animal; Er | 1995 |
Intravenous antihypertensive agents for patients unable to take oral medications.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Enalaprilat; Furosem | 1995 |
Triplex-DNA stabilization by hydralazine and the presence of anti-(triplex DNA) antibodies in patients treated with hydralazine.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Antihypertensive Agents; Circular Dichroism; DNA; Female | 1995 |
Proximal and distal pulse pressure after acute antihypertensive vasodilating drugs in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Heart Rate; Hydralazine; H | 1995 |
Plasma adrenaline responses to long-term modification of blood pressure in normotensive rats and hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Epinephrine; Hydralazine; Hypertension; Male; NG-Nitroarginine Me | 1995 |
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as | 1995 |
Oral calcium carbonate administration ameliorates the progression of renal failure in rats with hypertension.
Topics: Administration, Oral; Aluminum Hydroxide; Animals; Calcium Carbonate; Desoxycorticosterone; Doxorubi | 1995 |
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
Topics: Female; Humans; Hydralazine; Hypertension; Pre-Eclampsia; Pregnancy | 1995 |
Role of presynaptic beta 2-adrenergic facilitation in the development and maintenance of DOCA-salt hypertension.
Topics: Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catec | 1993 |
Influence of isradipine treatment on the morphology of the aorta in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Hydralazine; Hypertension; Isradipine; Male; Microscopy, Electron; M | 1994 |
Effects of captopril and hydralazine on progression of adriamycin nephropathy in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Captopril; Doxorubicin; Female; Glomerulonephritis; Hematocrit | 1994 |
Nifedipine aggravates cyclosporine A-induced gingival hyperplasia.
Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Gingival Hyperplas | 1994 |
Hydralazine boluses for the treatment of severe hypertension in pre-eclampsia.
Topics: Adult; Blood Pressure; Clinical Protocols; Female; Gestational Age; Humans; Hydralazine; Hydrogen-Io | 1994 |
TxA2-PGI2-PGF2 alfa responses in the kidney to blood pressure reduction induced by vasodilator/vasorelaxing agents with different action in patients with essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Dinoprost; Epoprostenol; Female; Gallopamil; Glomerular Filtratio | 1993 |
Acute myocardial infarction in patients treated for hypertension in the Skaraborg Hypertension Project.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Benzothiadiazines; Case-Control Studies; Diuretics; Drug T | 1993 |
Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Hydra | 1994 |
Angiotensin II alters aortic fibronectin independently of hypertension.
Topics: Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Fibronectins; Humans; Hydralazin | 1994 |
Angiotensin converting enzyme inhibition prevents the increase in aortic collagen in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; C | 1994 |
Alterations in vascular structure and function after short-term losartan treatment in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Hydra | 1993 |
Elastic behaviour of the carotid artery in intact spontaneously hypertensive rats.
Topics: Animals; Captopril; Carotid Artery, External; Compliance; Hydralazine; Hypertension; Male; Rats; Rat | 1993 |
Hydralazine induces Z-DNA conformation in a polynucleotide and elicits anti(Z-DNA) antibodies in treated patients.
Topics: Acetylation; Adolescent; Adult; Antibodies, Monoclonal; Autoantibodies; DNA; Enzyme-Linked Immunosor | 1993 |
Effects of long-term antihypertensive treatment and aging on renal function and albumin excretion in primary hypertension.
Topics: Aging; Albuminuria; Case-Control Studies; Drug Therapy, Combination; Follow-Up Studies; Glomerular F | 1993 |
Age as a modifying factor on the effect of antihypertensive therapy in focal stroke in rats.
Topics: Age Factors; Animals; Blood Pressure; Brain Ischemia; Drug Administration Schedule; Hydralazine; Hyp | 1993 |
Spatial features of focal infarction after hydralazine treatment in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Cerebral Arteries; Cerebral Infarction; Cerebrovascular Circulation; Hydralazine; Hypertens | 1993 |
Defective 3,4-dihydroxyphenylalanine decarboxylation to dopamine in hydralazine-treated hypertensive patients may be pyridoxine remediable.
Topics: Adult; Cardiovascular System; Decarboxylation; Dihydroxyphenylalanine; Diuresis; Dopamine; Female; H | 1993 |
Commentary on Shigetomi and Kuchel's work on DOPA decarboxylation.
Topics: Catecholamines; Decarboxylation; Dihydroxyphenylalanine; Humans; Hydralazine; Hypertension | 1993 |
Effects of antihypertensive drugs on the progress of renal failure in hyperlipidemic Imai rats.
Topics: Animals; Antihypertensive Agents; Cholesterol; Drug Therapy, Combination; Enalapril; Hydralazine; Hy | 1993 |
Alteration of cardiac collagen phenotypes in hypertensive hypertrophy: role of blood pressure.
Topics: Animals; Blood Pressure; Captopril; Collagen; Hydralazine; Hypertension; Hypertrophy, Left Ventricul | 1993 |
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzi | 1993 |
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; B | 1995 |
Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain Chemistry; Chromatography, H | 1995 |
Angiotensin II causes weight loss and decreases circulating insulin-like growth factor I in rats through a pressor-independent mechanism.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pr | 1996 |
Endothelium-dependent relaxation in resistance arteries from spontaneously hypertensive rats: effect of long-term treatment with perindopril, quinapril, hydralazine or amlodipine.
Topics: Acetylcholine; Amlodipine; Animals; Antihypertensive Agents; Arginine; Bradykinin; Dose-Response Rel | 1996 |
Characterization of endothelium-dependent vasodilation and vasoconstriction in coronary arteries from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Coronary Vessels; Endothelium, Vascular; Heart R | 1996 |
Effects of long-term hydralazine treatment on myocardial structure and expression of myosin isogenes in cardiac pressure overload in rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models | 1996 |
Hydralazine reduces elevated sleep apnea index in spontaneously hypertensive (SHR) rats to equivalence with normotensive Wistar-Kyoto rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Electroencephalography; Electromyography; Hydralaz | 1996 |
Effect of 14 years of antihypertensive treatment on renal function and urinary albumin excretion in primary hypertension.
Topics: Adrenergic beta-Antagonists; Albuminuria; Antihypertensive Agents; Benzothiadiazines; Blood Pressure | 1996 |
Equipotent antihypertensive agents variously affect pulsatile hemodynamics and regression of cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Captopril; Cardiomegaly; Hemodynamics; Hydralazine; Hypertension; | 1996 |
Spinal nicotinic receptor expression in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cysteine; | 1996 |
The renin angiotensin system and nociception in spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 1995 |
Lack of vasodilatory response in skeletal muscle blood vessels of aged spontaneously hypertensive rats.
Topics: Age Factors; Animals; Hemodynamics; Hydralazine; Hypertension; Muscle, Skeletal; Rats; Rats, Inbred | 1996 |
Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP).
Topics: Animals; Antioxidants; Blood Pressure; Calcium Channel Blockers; Catalase; Cerebrovascular Disorders | 1997 |
Alterations in alpha subunit expression of cardiac Na+,K+-ATPase in spontaneously hypertensive rats: effect of antihypertensive therapy.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hy | 1997 |
Effects of antihypertensive drugs or glycemic control on antioxidant enzyme activities in spontaneously hypertensive rats with diabetes.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitu | 1997 |
Myocardial stiffness is attributed to alterations in cross-linked collagen rather than total collagen or phenotypes in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Body Weight; Captopril; Collagen; Cross-Linking Reagents; Diastole | 1997 |
Lovastatin prevents development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Extracellular Space; Glomerular Filtra | 1997 |
Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diabetes Mellitus, Type | 1997 |
Increased expression of parathyroid hormone-related peptide gene in blood vessels of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood V | 1997 |
Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Chemokine CCL2; Hydralazine; Hypertension; Infusions | 1997 |
Effects of antihypertensive drugs on antioxidant enzyme activities and renal function in stroke-prone spontaneously hypertensive rats.
Topics: Acetylglucosaminidase; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; B | 1997 |
Investigation of the inhibitory effect of N(G)-nitro-L-arginine methyl ester on the antihypertensive effect of the angiotensin AT1 receptor antagonist, GR138950.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Benzofurans; Blood Pressu | 1997 |
Antihypertensive agents that limit ventricular hypertrophy inhibit cardiac expression of insulin-like growth factor-I.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hydralazine; Hypertension; Hyper | 1997 |
Endothelin-A receptor antagonist combined with hydralazine improves survival and renal function in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Endothelin Receptor Antagonists; Hydralazine; Hype | 1998 |
[Effects of doxazosin and hydralazine on insulin sensitivity and sympathetic function in spontaneously hypertensive rat (SHR)].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Doxazosin; Hydralazine; Hypertension | 1998 |
Regulation of extracellular matrix proteins in pressure-overload cardiac hypertrophy: effects of angiotensin converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Extracellular Matrix Pro | 1998 |
Hydralazine prevents endothelial dysfunction, but not the increase in superoxide production in nitric oxide-deficient hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Blotting, Western; Ditiocarb; Endothelium, Vascular; Female; | 1998 |
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; An | 1998 |
Reduced periinfarction mortality as a result of long-term therapy with captopril but not hydralazine or propranolol in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Collagen; Electric Stimulation; Heart R | 1998 |
Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cat | 1998 |
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Cell Nucleus; Diastole; DNA; | 1999 |
Antihypertensive mechanisms underlying a novel salt-sensitive hypertensive model induced by sensory denervation.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Body Weight; Calcitonin Gene-Rel | 1999 |
Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypert | 1999 |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Humans; Hydralazine; Hyperte | 1999 |
Long-term treatment with angiotensin converting enzyme inhibitor restores reduced calcitonin gene-related peptide-containing vasodilator nerve function in mesenteric artery of spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; | 1999 |
Isradipine and insulin sensitivity in hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glucose Clamp T | 1999 |
Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive A | 1999 |
Role of the sympathetic control of vascular resistance in ethanol-clonidine hemodynamic interaction in SHRs.
Topics: Animals; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Et | 1999 |
Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Captopril; | 1999 |
Characterization of MAP kinase and PKC isoform and effect of ACE inhibition in hypertrophy in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Enzyme Act | 1999 |
Increased leukotriene A(4) hydrolase expression in the heart of angiotensin II-induced hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Epoxide Hyd | 1999 |
The angiotensin-converting enzyme inhibitor, fosinopril, and the angiotensin II receptor antagonist, losartan, inhibit LDL oxidation and attenuate atherosclerosis independent of lowering blood pressure in apolipoprotein E deficient mice.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Apolipop | 1999 |
Nitric oxide and preglomerular vascular lesions in lyon spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Azo Compounds; Coloring Agents; Drug Combinations; Enzyme I | 2000 |
Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Diabetic | 1999 |
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Line, Transformed; Disease Mo | 2000 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats: an historical account and some follow-up.
Topics: Animals; Bibliometrics; Clonidine; Heart; History, 20th Century; Hydralazine; Hypertension; Methyldo | 2000 |
Angiotensin II-induced cardiomyocyte hypertrophy and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2000 |
Pre-eclampsia is associated with marked alterations in sleep architecture.
Topics: Adult; Antihypertensive Agents; Clonidine; Electroencephalography; Electrooculography; Female; Human | 2000 |
Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Captopril; Collagen; Coronary Vessels; Hyd | 2000 |
Lisinopril reduces left ventricular hypertrophy and cardiac polyamine concentrations without a reduction in left ventricular wall stress in transgenic Tsukuba hypertensive mice.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hydralazine; Hypertension; Hypertrophy, Left Ventr | 2000 |
Severe hypertension following ephedrine administration in a patient receiving entacapone.
Topics: Aged; Anesthetics, Intravenous; Antihypertensive Agents; Antiparkinson Agents; Catechols; Drug Inter | 2000 |
Occurrence and distribution of atrial natriuretic peptide-containing cells in the left ventricle of hypertensive rats. Effect of antihypertensive treatment.
Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Blotting, Northern; Cap | 2001 |
AT1 receptor antagonist combats oxidative stress and restores nitric oxide signaling in the SHR.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compoun | 2001 |
Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angioten | 2001 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine | 2001 |
Abnormal platelet function and calcium handling in Dahl salt-hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Platelets; Blood Pressure; Calcium; Ca | 2001 |
The influence of chronic antihypertensive treatment on the central pressor response in SHR.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl | 2001 |
Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Calcium Channel Blockers; Cerebrovascular C | 2001 |
Hemorrhagic transformation after fibrinolysis with tissue plasminogen activator: evaluation of role of hypertension with rat thromboembolic stroke model.
Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Brain; Cerebral Hemorrhage; Cerebr | 2001 |
Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertension.
Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Comorbidity; Disease Susceptibility; Female; | 2001 |
Evaluation of cardiovascular parameters of a selenium-based antihypertensive using pulsed Doppler ultrasound.
Topics: Animals; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Drug Administration Schedule; | 2001 |
Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhib | 2001 |
Changes of retinal neurons and glial fibrillary acid protein immunoreactive astrocytes in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Astrocytes; Glial Fibrillary Acidic Protein; Hydralazine; Hyperten | 2001 |
Attenuation of cardiac failure, dilatation, damage, and detrimental interstitial remodeling without regression of hypertrophy in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Collagen; Heart Failure; Heart Ventri | 2001 |
Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice.
Topics: Animals; Antihypertensive Agents; Aortic Aneurysm; Apolipoproteins E; Arteriosclerosis; Blood Pressu | 2001 |
Spinal nicotinic receptor activity in a genetic model of hypertension.
Topics: Alkaloids; Animals; Antihypertensive Agents; Azocines; Blood Pressure; Captopril; Desoxycorticostero | 2001 |
Autoregulation of blood flow, endothelial nitric oxide synthase and microvascular rarefaction.
Topics: Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Capillaries; Homeostasis; Humans; Hydr | 2002 |
Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme.
Topics: Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Body Weight; Capillaries; Disease Mode | 2002 |
Hydrallazine and beta-blockade in refractory hypertension with characterization of acetylator phenotype.
Topics: Acetylation; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hy | 1975 |
[New viewpoints on the causes and treatment of hypertension].
Topics: Adrenergic alpha-Antagonists; Humans; Hydralazine; Hypertension; Vasodilator Agents | 1976 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertensio | 1977 |
Peripheral haemodynamics in essential hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Huma | 1977 |
[Advances in the treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Hemodynamics; Humans; Hydralazine; Hypertensio | 1977 |
Labetalol in the treatment of hypertensive renal patients.
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydral | 1978 |
Hydrallazine and prazosin.
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Prazosin; | 1978 |
Therapeutic trials in mild hypertension ongoing throughout the world.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Diuretics; Fem | 1978 |
Treatment of severe and resistant hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diet, Sodium-Restricted; | 1978 |
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H | 1978 |
[Treatment of arterial hypertension in the aged].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Antihypertensive Agents; Clonidine; Diuretics; Human | 1978 |
Minoxidil in refractory hypertension. Effects on blood pressure, plasma volume and muscle blood flow.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cattle; Diuretics; Drug Evaluation; Drug Thera | 1979 |
Approach to drug therapy for hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diu | 1979 |
Effect of treatment of hypertension in the primary preventive trial, Göteborg, Sweden.
Topics: Adrenergic beta-Antagonists; Bethanidine; Cardiovascular Diseases; Cerebrovascular Disorders; Corona | 1979 |
[The treatment of critical hypertension with depressan and obsidan infusions].
Topics: Adrenergic beta-Antagonists; Cardiac Output; Dihydralazine; Drug Therapy, Combination; Humans; Hydra | 1979 |
Review: the significance and management of raised blood pressure in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlormethiazole; Clonidine; Diazepam; D | 1979 |
Changes in glomerular filtration rate during long term treatment with propranolol and peripheral vasodilators in patients with arterial hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hyperte | 1979 |
Antihypertensive and cardiac effects of two novel beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Butylamines; Heart; H | 1979 |
[Combination of beta-blocking agents, diuretics and pressidil (minoxidil) in severe arterial hypertension resisting other therapy].
Topics: Adrenergic beta-Antagonists; Adult; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Fu | 1978 |
Hydralazine-induced lupus erythematosus-like syndrome.
Topics: Acetylation; Acetyltransferases; Antibodies, Antinuclear; Arthritis, Rheumatoid; Child; DNA; Drug Hy | 1975 |
Letter: Bromocriptine and hypertension.
Topics: Acromegaly; Adult; Blood Pressure; Bromocriptine; Drug Therapy, Combination; Ergolines; Humans; Hydr | 1976 |
HYDRALLAZINE.
Topics: Drug Evaluation; Humans; Hydralazine; Hypertension | 1977 |
Diabetes and hypertension.
Topics: Blood Pressure; Diabetes Mellitus; Diabetic Nephropathies; Furosemide; Glomerular Filtration Rate; H | 1979 |
Lymphocytotoxic antibodies in hydralazine-induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Antibody-Dependent Cell Cytotoxicity; Humans; Hydralazine; Hypertension; Lu | 1979 |
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazi | 1976 |
Relationship between blood pressure of spontaneously hypertensive rats and alterations in membrane properties of mesenteric arteries.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Blood Pressure; Body Weight; Calcium; Cell | 1977 |
[Regression of left ventricular hypertophy in the ECG during antihypertensive treatment: preliminary observations (author's transl)].
Topics: Adult; Aged; Cardiomegaly; Chlorthalidone; Electrocardiography; Female; Humans; Hydralazine; Hyperte | 1979 |
Effects of antihypertensive treatment on left ventricular hypertrophy in patients with essential hypertension.
Topics: Adult; Aged; Animals; Antihypertensive Agents; Cardiomegaly; Electrocardiography; Female; Heart Vent | 1979 |
Time course of changes in plasma renin after blockade of the renin-system. Studies of conscious and anaesthetized, normal, adrenalectomized and spontaneously hypertensive rats.
Topics: Adrenalectomy; Anesthesia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood | 1975 |
Hypertension-accelerated atherogenesis in cholesterol-fed rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Blood Pressure; Cholesterol; Cholesterol, Dietary; Hydralazine; Hy | 1977 |
Drug-induced peripheral neuropathies.
Topics: Humans; Hydralazine; Hypertension; Peripheral Nervous System Diseases | 1979 |
Unimpaired beta adrenergic responses during prazosin administration.
Topics: Blood Glucose; Blood Pressure; Dopamine beta-Hydroxylase; Heart Rate; Humans; Hydralazine; Hypertens | 1979 |
The clinical pharmacology of hypotensive vasodilator drugs.
Topics: Adrenergic beta-Antagonists; Blood Vessels; Cardiac Output; Diuretics; Drug Therapy, Combination; Hu | 1975 |
Antihypertensive drugs and catecholamine metabolism: effects of reserpine and hydralazine on tyrosine hydroxylase activity and norepinephrine concentrations in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Chlorisondamine; F | 1975 |
[Drug therapy of hypertension in general practice].
Topics: Adrenergic beta-Antagonists; Adult; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyld | 1975 |
Hypotensive agents. Part I: Vasodilators.
Topics: Diazoxide; Humans; Hydralazine; Hypertension; Prazosin; Quinazolines | 1979 |
Drug treatment of mild hypertension: adverse consequences.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Female; Guaneth | 1978 |
Primary hypertension refractory to triple drug treatment - a study on central and peripheral hemodynamics.
Topics: Bendroflumethiazide; Drug Therapy, Combination; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazi | 1979 |
Echocardiographic assessment of the effect of an antihypertensive regimen on left ventricular performance.
Topics: Adult; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Chlorthalidone; Coronary Disease | 1979 |
Evaluation of a program of bed rest in the treatment of chronic hypertension in pregnancy.
Topics: Bed Rest; Birth Weight; Chronic Disease; Female; Fetal Death; Humans; Hydralazine; Hypertension; Inf | 1979 |
Dihydralazine therapy and acetylator phenotype.
Topics: Acetylation; Adult; Aged; Creatinine; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Male | 1979 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases | 1979 |
Hypertension in the elderly: special considerations in treatment.
Topics: Aged; Benzothiadiazines; Diuretics; Hospitalization; Humans; Hydralazine; Hypertension; Patient Comp | 1979 |
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Hu | 1979 |
Guidelines for evaluating and treating hypertension.
Topics: Aged; Antihypertensive Agents; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Guanethidine | 1979 |
When to use oral vasodilators for hypertension.
Topics: Administration, Oral; Diazoxide; Humans; Hydralazine; Hypertension; Minoxidil; Prazosin; Vasodilator | 1979 |
Drug treatment of essential hypertension. Practical guidelines.
Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; M | 1979 |
[Use of Adelphan-Esidrex in treating hypertension].
Topics: Adult; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Midd | 1979 |
Dihydralazine and catecholamine-synthesizing enzymes in spontaneous hypertension.
Topics: Adrenal Medulla; Animals; Blood Pressure; Catecholamines; Dihydralazine; Ganglia, Sympathetic; Hydra | 1979 |
Traction-related hypertension in children.
Topics: Adolescent; Humans; Hydralazine; Hypertension; Male; Propranolol; Renin; Traction | 1979 |
Influence of clonidine, alpha-methyldopa and hydralazine on noradrenergic and adrenergic neuronal activities in brainstem nuclei of spontaneously hypertensive rats [proceedings].
Topics: Animals; Brain Stem; Clonidine; Dopamine beta-Hydroxylase; Hydralazine; Hypertension; Methyldopa; Ph | 1979 |
[Can lupus be caused by dihydralazine?].
Topics: Adult; Aged; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic | 1979 |
[3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes].
Topics: Animals; Antihypertensive Agents; Hydralazine; Hydrazines; Hypertension; Pyridazines; Rats; Todralaz | 1979 |
Effects on rat urinary kallikrein excretion of bumetanide, bendroflumethiazide and hydralazine.
Topics: Administration, Oral; Animals; Bendroflumethiazide; Bumetanide; Diuretics; Hydralazine; Hypertension | 1977 |
Hypotension and bradycardia following diazoxide and hydralazine therapy.
Topics: Bradycardia; Diazoxide; Humans; Hydralazine; Hypertension; Hypotension; Male; Middle Aged | 1977 |
Glucocorticoid therapy for the induction of pulmonary maturity in severely hypertensive gravid women.
Topics: Betamethasone; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Labor, Induced; Pre-Eclam | 1979 |
[Simultaneous administration of dihydralazine, propranolol and a diuretic in the treatment of severe hypertension].
Topics: Adolescent; Adult; Dihydralazine; Diuretics; Drug Therapy, Combination; Female; Humans; Hydralazine; | 1977 |
Combined clonidine and hydralazine therapy in severe and refractory hypertension.
Topics: Adult; Blood Pressure; Chronic Disease; Clonidine; Drug Evaluation; Drug Therapy, Combination; Femal | 1977 |
Sinus tachycardis in a hypertensive patient: drug withdrawal phenomenon?
Topics: Arrhythmia, Sinus; Female; Humans; Hydralazine; Hypertension; Middle Aged; Propranolol; Substance Wi | 1977 |
The comeback of hydralazine.
Topics: Drug Therapy, Combination; Hemodynamics; Humans; Hydralazine; Hypertension; Propranolol | 1978 |
[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine].
Topics: Adult; Dihydralazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydro | 1978 |
[Hemodynamic parameters and plasma-renin activity following intravenous dihydralazine administration--a contribution to the regulation of renin].
Topics: Adolescent; Adult; Arterial Occlusive Diseases; Dihydralazine; Female; Glomerulonephritis; Humans; H | 1978 |
The effects of antihypertensive medication on the control of the cardiovascular system during halothane anaesthesia in rats.
Topics: Anesthesia, Inhalation; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation | 1978 |
Electrophysiologic effects of hydralazine on sinoatrial function in patients with sick sinus node syndrome.
Topics: Aged; Arrhythmia, Sinus; Blood Pressure; Cardiac Pacing, Artificial; Female; Heart Rate; Humans; Hyd | 1978 |
Renal plasma flow and cardiac output during hydralazine and propranolol treatment in essential hypertension.
Topics: Adult; Cardiac Output; Drug Evaluation; Drug Therapy, Combination; Humans; Hydralazine; Hypertension | 1978 |
Changes in plasma volume and extracellular fluid volume and after addition of hydralazine to propranolol treatment in patients with hypertension.
Topics: Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Extracellular Space; Female; Humans; Hydral | 1978 |
Management of hypertension in the patient with chronic renal disease.
Topics: Blood Pressure; Diuretics; Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hypertensi | 1978 |
Malignant hypertension: clinical recognition and management.
Topics: Adult; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Kidney; Male; | 1978 |
Clinical management of pregnancy-induced hypertension.
Topics: Age Factors; Ambulatory Care; Delivery, Obstetric; Female; Gestational Age; Hospitalization; Humans; | 1978 |
Treatment with propranolol and hydralazine throughout pregnancy in a hypertensive patient. A case report.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Pregnancy; Pregnancy Co | 1978 |
Hemodynamic responsiveness to short- and long-acting vasodilators in left ventricular failure.
Topics: Blood Pressure; Cardiac Output; Delayed-Action Preparations; Heart Failure; Heart Rate; Heart Ventri | 1978 |
Primary hypertension refractory to triple drug treatment: a study on central and peripheral hemodynamics.
Topics: Benzothiadiazines; Blood Pressure; Cardiac Volume; Diuretics; Drug Resistance; Drug Therapy, Combina | 1978 |
[Ergometry in the assessment of antihypertensive treatment (author's transl)].
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Female; Humans; Hydralazine; Hypertension; Mal | 1978 |
The hypertensive psychiatric patient: pharmacologic problems.
Topics: Antihypertensive Agents; Clonidine; Depression; Diuretics; Drug Interactions; Guanethidine; Humans; | 1978 |
Self-control, biofeedback, and change in 'psychosomatic' approach.
Topics: Adult; Biofeedback, Psychology; Chlordiazepoxide; Humans; Hydralazine; Hypertension; Middle Aged; Ps | 1978 |
Partial characterization of aortic renin in the spontaneously hypertensive rat and its interrelationship with plasma renin, blood pressure and sodium balance.
Topics: Angiotensin I; Animals; Aorta; Blood Pressure; Female; Hydralazine; Hypertension; Male; Metolazone; | 1978 |
Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Electric Stimulation; Hydralazine; Hypertension; Hyp | 1978 |
Leukocyte intracellular cations in hypertension: Effect of antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension | 1978 |
[Treatment of hypertension with a combination of the adrenergic beta receptor blockader, obsidan, and the vasodilator, apressin].
Topics: Adult; Blood Pressure; Drug Synergism; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; | 1978 |
Pharmacology of budralazine, a new antihypertensive drug.
Topics: Animals; Antihypertensive Agents; Dogs; Female; Heart Rate; Hydralazine; Hypertension; Male; Methyld | 1978 |
Efficacy of a combination of diuretic, beta-blocker and vasodilator in the treatment of hypertension in general practice.
Topics: Adult; Aged; Cyclopenthiazide; Delayed-Action Preparations; Diuretics; Drug Therapy, Combination; Fa | 1978 |
Workup and treatment of the average hypertensive patient.
Topics: Benzothiadiazines; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa | 1978 |
Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy.
Topics: Apgar Score; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Growth Retardation; Fetus; Hu | 1978 |
[Peripheral vasodilators in the treatment of hypertension. A review].
Topics: Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Prazosin; Quinazolines | 1979 |
[Equilibration of the treatment of severe arterial hypertension. Significance of d-1 propranolol].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hydralazine; Hypertension; Long-Ter | 1975 |
Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta.
Topics: Animals; Aortic Coarctation; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol, Dietary; Co | 1976 |
The management of severe pre-eclampsia and eclampsia.
Topics: Chlormethiazole; Delivery, Obstetric; Diazepam; Diuretics; Eclampsia; Female; Humans; Hydralazine; H | 1977 |
Immune hemolysis due to hydralazine.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Humans; Hydralazine; Hypertension; Male; Middle Ag | 1977 |
Hypertension and haematomas: prophylaxis with apresoline.
Topics: Aged; Face; Female; Hematoma; Humans; Hydralazine; Hypertension; Middle Aged; Postoperative Complica | 1977 |
Treatment of chronic essential hypertension.
Topics: Chlorothiazide; Clonidine; Diabetes Mellitus; Diet, Sodium-Restricted; Gout; Guanethidine; Humans; H | 1977 |
Elevated blood pressure in the young adult.
Topics: Adult; Age Factors; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Patient Care Planning; R | 1977 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
[Dihydralazine-induced hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Humans; Hydralazine; Hypertension; Lupus Eryt | 1977 |
[Dihydralazine-induced acute hepatitis with IgM deficiency].
Topics: Acetylation; Aged; Antibodies; Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersens | 1977 |
[Liver damage caused by adelphan].
Topics: Aged; Aspartate Aminotransferases; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Jaundic | 1977 |
The effect of norepinephrine on aortic 42K turnover during deoxycorticosterone acetate hypertension and antihypertensive therapy in the rat.
Topics: Animals; Antihypertensive Agents; Aorta; Arteries; Desoxycorticosterone; Dose-Response Relationship, | 1977 |
Physiologic mechanisms of bupicomide- and hydralazine-induced increase in plasma renin activity in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Fusaric Acid; Heart Rate; Humans; Hydralazin | 1977 |
Comparison of the efficacy of diazoxide and hydrallazine in the control of severe hypertension at the Kenyatta National Hospital, Nairobi: a preliminary report.
Topics: Diazoxide; Humans; Hydralazine; Hypertension | 1977 |
Survival in hydralazine-treated hypertensive patients with and without late toxicity.
Topics: Blood Pressure; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged | 1977 |
Comparison of nitroprusside and hydralazine in hypertensive pregnant ewes.
Topics: Animals; Cardiac Output; Female; Ferricyanides; Heart Rate; Hydralazine; Hypertension; Nitroprusside | 1977 |
Plasma renin concentration in essential hypertension during beta-adrenergic blockade and vasodilator therapy.
Topics: Adult; Alprenolol; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertens | 1977 |
Drugs in the treatment of hypertension: pharmacology and interactions.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hypertension; Male; Methyldopa; Proprano | 1977 |
Office management of hypertension.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hyperten | 1976 |
Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate, and renal plasma flow in patients with essential hypertension.
Topics: Aged; Albuminuria; Alprenolol; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Guinea P | 1976 |
Drugs in the management of hypertension. Part III.
Topics: Antihypertensive Agents; Diazoxide; Drug Therapy, Combination; Ferricyanides; Guanidines; Humans; Hy | 1976 |
Proceedings: Effects of prolonged oral administration of hydralazine on reflex bradycardia in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Bradycardia; Disease Models, Animal; Hydralazine; Hypertension; Press | 1976 |
A nurse clinician's role in the management of hypertension.
Topics: Adult; Aged; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Nurse Practit | 1976 |
[Prazosin, a new peripheral vasodilator agent compared with hydralazine].
Topics: Antihypertensive Agents; Drug Evaluation; Humans; Hydralazine; Hypertension; Vasodilator Agents | 1976 |
Progression of nephropathy in long-term diabetics with proteinuria and effect of initial anti-hypertensive treatment.
Topics: Adolescent; Adult; Albuminuria; Diabetic Nephropathies; Furosemide; Glomerular Filtration Rate; Huma | 1976 |
Pediatric hypertension: current therapeutic considerations.
Topics: Adolescent; Child; Child, Preschool; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hypertens | 1976 |
Haemodynamic adaptation at rest and during exercise to long-term antihypertensive treatment with combination of beta-receptor blocking and vasodilator agent.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypert | 1976 |
Bioassay of the vasodepressor and cardiostimulatory effects of hydralazine and pyridazine derivative (DL-150) in hypertensive patients.
Topics: Aged; Biological Assay; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hydralazine; Hyper | 1976 |
[Therapeutic combinations, side effects and interactions of antihypertensive drugs].
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Dihydralazine; Diuretics; Drug Interactions; | 1976 |
[Treatment of hypertensive crises].
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Humans; Hydralazine; Hypertension; Methyldopa; Nitrop | 1976 |
Effect of timolol on hydralazine-induced increase in plasma renin activity in spontaneously hypertensive and normotensive rats.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Hydralazine; Hypertension; Propanol | 1976 |
[Evaluation of the therapeutic effect of dopegit and depressin in hypertension according to polycardiographic data].
Topics: Adult; Aged; Antihypertensive Agents; Depression, Chemical; Dihydralazine; Drug Evaluation; Female; | 1976 |
[Clinical considerations on a group of patients with arterial hypertension treated with propranolol].
Topics: Bradycardia; Diuretics; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Propranolol | 1976 |
Relative effectiveness of chlorothiazide, reserpine and hydrallazine in spontaneously hypertensive rats.
Topics: Animals; Chlorothiazide; Hydralazine; Hypertension; Rats; Reserpine; Time Factors | 1976 |
Minoxidil in refractory hypertension.
Topics: Blood Pressure; Child; Creatinine; Female; Furosemide; Humans; Hydralazine; Hypertension; Kidney Tra | 1975 |
[Drug combinations in the treatment of primary arterial hypertension].
Topics: Antihypertensive Agents; Blood Volume; Cardiac Output; Diuretics; Drug Combinations; Drug Therapy, C | 1975 |
The early detection and treatment of hypertension.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorothiazide; Diuretics; Female; Florida; Furose | 1975 |
Prognostic and therapeutic considerations in pure hypertension vs hypertension and superimposed arteriosclerosis.
Topics: Arteriosclerosis; Blood Pressure; Cold Temperature; Digitalis; Female; Follow-Up Studies; Humans; Hy | 1975 |
Diuretics, beta blockers and vasodilators. Dosage in mild and moderate hypertension.
Topics: Cyclopenthiazide; Diuretics; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Male; Mid | 1975 |
Oxprenolol and hydrallazine in the treatment of hypertension.
Topics: Adult; Diuretics; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Methyl | 1975 |
Detection and treatment of hypertension at the work site.
Topics: Aged; Allied Health Personnel; Costs and Cost Analysis; Delivery of Health Care; Female; Humans; Hyd | 1975 |
Acetylator phenotype and the antihypertensive response to hydralazine.
Topics: Acetylation; Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydralazine; Hyper | 1975 |
The urinary excretion of trace elements before and during treatment with hydralazine.
Topics: Adult; Depression, Chemical; Humans; Hydralazine; Hypertension; Male; Middle Aged; Stimulation, Chem | 1975 |
Evaluation of antihypertensive agents in the stress-induced hypertensive rat.
Topics: Animals; Antihypertensive Agents; Chlorisondamine; Disease Models, Animal; Drug Evaluation, Preclini | 1975 |
Pathogenesis of acute arterial fat deposition in spontaneously hypertensive rats.
Topics: Acute Disease; Animals; Arteries; Capillary Permeability; Cerebral Arteries; Cholesterol, Dietary; H | 1975 |
Experimental studies on the pathogenesis and prophylaxis of stroke in stroke-prone spontaneously hypertensive rats (SHR). (2) Prophylactic effect of moderate control of blood pressure on stroke.
Topics: Animals; Carbidopa; Carboxy-Lyases; Cerebrovascular Disorders; Heart Rate; Hydralazine; Hypertension | 1975 |
Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
Topics: Cardiac Catheterization; Drug Therapy, Combination; Echocardiography; Edema; Furosemide; Humans; Hyd | 1975 |
3-Hydroxymethyl-s-triazolo[3,4-a]phthalazine, a novel urinary hydralazine metabolite in man.
Topics: Humans; Hydralazine; Hypertension; Mass Spectrometry; Phthalazines; Pyridazines; Triazoles | 1975 |
Therapy and prognosis of hypertension in chronic nephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extra | 1975 |
Relationship between plasma renin activity and blood pressure response to antihypertensive agents. A proposal for management of essential and renal hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Furosemide; Humans; Hydralazine; Hypert | 1975 |
[Diazoxide: new way in treatment of hypertension].
Topics: Adult; Chlorthalidone; Diazoxide; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension | 1975 |
Treatment of hypertensive emergencies.
Topics: Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Reserpine; Tri | 1975 |
Hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Cooperative Behavior; Diet Therapy; Diuretics; Humans; H | 1975 |
How far should blood pressure be lowered in treating hypertension.
Topics: Blood Pressure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1975 |
Editorial: Hypertension is worth treating.
Topics: Blood Pressure; Cardiovascular Diseases; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide | 1975 |
The hypertensive patient. An algorithm for treatment.
Topics: Administration, Oral; Blood Pressure; Blood Urea Nitrogen; Clonidine; Creatinine; Diazoxide; Diureti | 1975 |
Influence of anti-hypertensive drug treatment on vascular reactivity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Hydralazine; Hydrochlorothiazide; Hyperten | 1975 |
Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension.
Topics: Adult; Aged; Alprenolol; Depression, Chemical; Drug Therapy, Combination; Female; Humans; Hydralazin | 1975 |
Catecholamines in plasma and urine in patients with essential hypertension determined by double-isotope derivative techniques.
Topics: Adult; Age Factors; Aged; Alprenolol; Dopamine; Drug Therapy, Combination; Epinephrine; Female; Huma | 1975 |
The treatment of gestational hypertension.
Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype | 1975 |
Effect of treatment on longevity in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Chlorothiazide; Female; Hydralazine; Hypertension; Longevity; | 1975 |
[Treatment of hypertension with propranolol in combination with other antihypertensive agents].
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorot | 1975 |
Antihypertensive therapy with hydralazine and propranolol: a case history.
Topics: Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Middle Aged; P | 1975 |
[Treatment of hypertension using propranolol combined with hydralazine and a thiazidine diuretic. 1st results].
Topics: Adult; Aged; Bendroflumethiazide; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertensi | 1975 |
Some side-effects of alpha-methyldopa.
Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Erectile Dysfunction; Humans; Hydralazine; H | 1976 |
Persistent reversal of severe systemic hypertension after prolonged toxic reaction to hydralazine.
Topics: Adult; Drug Hypersensitivity; Drug Therapy, Combination; Hexamethonium Compounds; Humans; Hydralazin | 1975 |
[Clinical experience with intravenous depressan ampules].
Topics: Adult; Aged; Antihypertensive Agents; Dihydralazine; Humans; Hydralazine; Hypertension; Injections, | 1975 |
Drugs in the management of hypertensive emergencies in children. Notes and comments on currently popular agents.
Topics: Antihypertensive Agents; Child; Diazoxide; Diuretics; Drug Combinations; Drug Therapy, Combination; | 1976 |
Drug regimens for long-term therapy of hypertension.
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; | 1976 |
Applied pharmacology of anti-hypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hyperte | 1976 |
Letter: Elaboration on clinical case.
Topics: Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Propranolol | 1976 |
Treatment of hypertension in middle-aged men. A feasibility study in a community.
Topics: Blood Pressure Determination; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Male; Mi | 1976 |
Letter: Impotence during antihypertensive treatment.
Topics: Adult; Erectile Dysfunction; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male | 1976 |
Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study.
Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Hydralazine; Hypertension; Male; Microscopy, El | 1992 |
Effects of enalapril and hydralazine treatment and withdrawal upon cardiovascular hypertrophy in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; DNA; Elastin; Enalapril; Heart Ventricles; Hydralazine; Hypert | 1992 |
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, A | 1992 |
Age-related changes in opioid peptide concentrations in brain and pituitary of spontaneously hypertensive rats. Effect of antihypertensive drugs and comparison with deoxycorticosterone acetate and salt hypertension.
Topics: Aging; Animals; beta-Endorphin; Brain; Desoxycorticosterone; Dynorphins; Endorphins; Enkephalin, Met | 1992 |
Chronic arterial vasodilation, central hemodynamics, and cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Drinking; Heart Rate; | 1992 |
Acetylation status using hydralazine in African hypertensives at Kenyatta National Hospital.
Topics: Acetylation; Administration, Oral; Adult; Aged; Arylamine N-Acetyltransferase; Female; Gene Frequenc | 1992 |
Management of hypertensive emergencies.
Topics: Adolescent; Child; Child, Preschool; Diazoxide; Emergencies; Female; Humans; Hydralazine; Hypertensi | 1992 |
Job absenteeism and arterial hypertension: results of a hypertension control program.
Topics: Absenteeism; Adult; Blood Pressure; Clinical Protocols; Costs and Cost Analysis; Diuretics; Humans; | 1992 |
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT.
Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardi | 1992 |
Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes.
Topics: Adrenal Glands; Angiotensin II; Animals; Endometrium; Female; Hydralazine; Hypertension; Injections, | 1992 |
Antihypertensive therapy in a model combining spontaneous hypertension with diabetes.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Gluco | 1992 |
Effect of antihypertensive treatment on focal cerebral infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain; C | 1992 |
Hydralazine does not restore uterine blood flow during cocaine-induced hypertension in the pregnant ewe.
Topics: Animals; Blood Pressure; Catecholamines; Cocaine; Female; Fetus; Heart Rate; Hydralazine; Hypertensi | 1992 |
Glomerular abnormalities in long-term experimental diabetes. Role of hemodynamic and nonhemodynamic factors and effects of antihypertensive therapy.
Topics: Albuminuria; Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; | 1992 |
Use of Tensiomin in hypertensive patients with impaired renal function.
Topics: Adult; Captopril; Creatinine; Humans; Hydralazine; Hypertension; Kidney; Kidney Failure, Chronic; Mi | 1992 |
Enhanced presynaptic beta 2-adrenergic facilitatory mechanism in conscious deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Epinephrine; Fenoterol; Heart Rate; Hydralazine; Hype | 1991 |
First-choice antihypertensive drug use in the Glasgow Blood Pressure Clinic.
Topics: Adrenergic beta-Antagonists; Ambulatory Care Facilities; Angiotensin-Converting Enzyme Inhibitors; A | 1990 |
Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Heart Rate | 1991 |
Long-term protective effects of nitrendipine in experimental hypertension.
Topics: Animals; Arteriosclerosis; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Endothelins; Hydr | 1991 |
[Reserpine and reserpine-containing preparations in hypertension?].
Topics: Diuretics; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Propra | 1992 |
Intravenously administered labetalol for treatment of hypertension in children.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Diazoxide; Heart Rate; Humans; Hydralazine; Hyperte | 1992 |
Maternal and fetal haemodynamics in hypertensive pregnancies during maternal treatment with intravenous hydralazine or labetalol.
Topics: Female; Heart Rate, Fetal; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Pregnancy; Pr | 1991 |
Contractile reactivity of isolated resistance arteries after 4 weeks of treatment with rilmenidine, clonidine or hydralazine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Clonidine; Hydralazine; Hypertension; In | 1991 |
Neither hydralazine nor captopril significantly shifts carotid artery distensibility-pressure curves determined in intact spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Captopril; Carotid Arteries; Elasticity; Hydralazine; Hypertension; Male; R | 1991 |
[Use of intravenous hydralazine in treatment of hypertensive crisis].
Topics: Adult; Aged; Blood Pressure; Drug Evaluation; Emergencies; Female; Heart Rate; Humans; Hydralazine; | 1991 |
Effects of antihypertensive therapy on mechanics of cerebral arterioles in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Cerebral Arteries; Ce | 1991 |
Atrial natriuretic factor and volume expansion-induced natriuresis in the spontaneously hypertensive rat.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Drinking; Hydralazine; Hypertensio | 1991 |
Effects of two angiotensin converting enzyme inhibitors and hydralazine on coronary circulation in hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Cilazapril; Coronary Cir | 1991 |
Reducing pulse pressure in hypertension may normalize small artery structure.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; | 1991 |
Protective effects of antihypertensive treatment with isradipine on the consequences of cerebral ischaemia in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Brain Ischemia; Hydralazine; Hypertension; Isradipine; Male; Motor | 1991 |
Renal arteriolar diameters in spontaneously hypertensive rats. Vascular cast study.
Topics: Aging; Animals; Arterioles; Blood Pressure; Body Weight; Captopril; Hydralazine; Hypertension; Kidne | 1991 |
[Effects of adelphan-esidrex on hemodynamic indexes at rest and character of their changes during exercise tests].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Exercise Test; Female; Hemodynamics; Humans | 1991 |
Effect of chronically administered hydralazine on altered adrenergic neurotransmission mediated by presynaptic alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Aging; Animals; Blood Pressure; Drug Administration Schedule; Electric Stimulatio | 1990 |
Effect of hydralazine on the mesenteric vasculature of hypertensive rats.
Topics: Animals; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Mesenteric Arteries; Rats; Rats, Inb | 1991 |
Cocaine intoxication associated with abruptio placentae.
Topics: Abruptio Placentae; Adult; Cocaine; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; Pr | 1991 |
Risk of serious morbidity associated with hydralazine versus methyldopa treatment in hypertensive patients.
Topics: Cardiovascular Diseases; Female; Humans; Hydralazine; Hypertension; Kidney Diseases; Male; Medical R | 1991 |
The effect of vasodilator therapy on the limb circulation in hypertension.
Topics: Arterial Occlusive Diseases; Female; Humans; Hydralazine; Hypertension; Intermittent Claudication; L | 1990 |
Effect on atrial natriuretic peptides of chronic treatment with alpha-methyldopa and hydralazine in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Heart Atria; Heart Ventricles; Hyd | 1990 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary | 1990 |
Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cilazapril; Endothelium | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensin | 1990 |
Nephropathy in model combining genetic hypertension with experimental diabetes. Enalapril versus hydralazine and metoprolol therapy.
Topics: Administration, Oral; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Melli | 1990 |
Vasodilators and hypertensive encephalopathy following scorpion envenomation in children.
Topics: Acute Disease; Animals; Brain Diseases; Child; Child, Preschool; Humans; Hydralazine; Hypertension; | 1990 |
Conversion of drug-induced SLE-syndrome by the vasodilating agent cadralazine.
Topics: Adult; Blood Pressure; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Pyrid | 1990 |
Constrictive pericarditis due to hydralazine-induced lupus erythematosus.
Topics: Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, C | 1990 |
Effect of calcium antagonists on hypertension and diabetes in new hypertensive diabetic models.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Disea | 1987 |
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexe | 1988 |
[Clinical application of vascular smooth muscle relaxants in the treatment of hypertension].
Topics: Guanidines; Humans; Hydralazine; Hypertension; Nitroglycerin; Parasympatholytics; Pinacidil; Pyridaz | 1989 |
Left ventricular hypertrophy in hypertensive patients.
Topics: Cardiomegaly; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Prazosin | 1989 |
Structural change in the rat hindlimb during deoxycorticosterone acetate hypertension; its reversibility and prevention.
Topics: Animals; Arterioles; Cardiomegaly; Desoxycorticosterone; Hindlimb; Hydralazine; Hypertension; Male; | 1989 |
Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hydralazine; Hypertension; Indoles; Isr | 1989 |
Captopril and hydralazine suppress atrial natriuretic peptide (ANP) gene expression in the ventricles of spontaneously hypertensive rat.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Captopril; Gene Expression Regulati | 1989 |
Vascular remodeling and improvement of coronary reserve after hydralazine treatment in spontaneously hypertensive rats.
Topics: Animals; Cardiac Volume; Cardiomegaly; Coronary Circulation; Coronary Vessels; Hydralazine; Hyperten | 1989 |
Myocardial collagen and mechanics after preventing hypertrophy in hypertensive rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Hemodynamics; Hydralazine; Hypertension; Myocardium | 1989 |
Enalapril retards glomerular basement membrane thickening and albuminuria in the diabetic rat: are these effects specific for enalapril?
Topics: Albuminuria; Animals; Basement Membrane; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic N | 1989 |
Outcome of pregnancies complicated by severe hypertension and delivered before 34 weeks; stepwise logistic regression analysis of prognostic factors.
Topics: Adult; Birth Weight; Cerebral Hemorrhage; Cesarean Section; Female; Fetal Growth Retardation; Gestat | 1989 |
Centrally acting alpha-2 agonists, peripherally acting adrenergic-blocking drugs, and direct vasodilators in the treatment of mild and moderate essential hypertension.
Topics: Adult; Aged; Black People; Clinical Protocols; Clonidine; Drug Therapy, Combination; Humans; Hydrala | 1989 |
Converting enzyme-inhibition in diabetic nephropathy.
Topics: Albuminuria; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Therapy, Combination; Furosemid | 1989 |
Effects of angiotensin converting enzyme inhibitors on the progression of renal failure and proteinuria in humans.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Female; Furos | 1989 |
Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report.
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; Lupus Vulgaris; Pregnancy; Pregna | 1989 |
Histometric assessment of renal arterioles during DOCA and post-DOCA hypertension and hydralazine treatment in rats.
Topics: Animals; Arterioles; Blood Pressure; Desoxycorticosterone; Hydralazine; Hypertension; Male; Rats; Ra | 1989 |
[Treatment of arterial hypertension in the aged].
Topics: Age Factors; Aged; Diet, Sodium-Restricted; Diuretics; Drug Therapy, Combination; Female; Humans; Hy | 1989 |
[Vasodilators in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diazoxide; Hemodynamics; Humans; Hydralazine; Hypertension; Minoxidil; Nit | 1989 |
Chronic but not acute treatment with hydralazine reverses the decreased endothelium-dependent responses in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Endothelium, Vascular; Female; Hydralazine; Hype | 1989 |
The endothelium and cyclic guanosine monophosphate in hyperthyroid-induced hypertension.
Topics: Acetylcholine; Animals; Biological Products; Cyclic GMP; Hydralazine; Hypertension; Hyperthyroidism; | 1987 |
Effects of the angiotensin converting enzyme inhibitor, lisinopril, on normal and diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diabetes Mellitus, Experimental; | 1988 |
Fatty acid binding protein of cardiac muscle in spontaneously hypertensive rats: effect of hypertrophy and its regression.
Topics: Animals; Blood Pressure; Cardiomegaly; Carrier Proteins; Enalapril; Fatty Acid-Binding Protein 7; Fa | 1988 |
Behavioural factors contribute to the development of spontaneous hypertension in rats.
Topics: Animals; Behavior, Animal; Blood Pressure; Captopril; Catecholamines; Hydralazine; Hypertension; Mal | 1985 |
Otolaryngologists using local anesthetics containing epinephrine.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Antihypertensive Agents; Drug Interactions; Epineph | 1985 |
[Optimization of hypotensive therapy in hospitals].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cerebrovascular Circulation; Clonidine; Drug C | 1985 |
Clinical pharmacology of vasodilator drugs.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Coronary Disease; Humans; Hydralazine; Hyper | 1985 |
Treatment of hypertension with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Costs and Cost Analysis; Diuretics; Fem | 1985 |
[Pharmacokinetic properties and indications for modern vasodilators. 1. Pharmacodynamic properties of vasodilators].
Topics: Adrenergic alpha-Antagonists; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Arrhythmias | 1985 |
[Hypertension in pregnancy: proposed monitoring and therapy].
Topics: Adrenergic beta-Antagonists; Captopril; Diuretics; Female; Follow-Up Studies; Humans; Hydralazine; H | 1985 |
[Treatment of hypertension with obsilazin].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Dihydralazine; Diuretics; Drug Combinat | 1986 |
Historical perspective on the management of hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazine | 1986 |
Effects of adrenergic receptor antagonists on cardiac morphological and functional alterations in rats harboring pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiom | 1987 |
Felodipine in combination with a beta-blocker and a diuretic in chronic treatment of patients with refractory primary hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy | 1987 |
Analysis of the mechanism underlying the vasodilator action of carvedilol in pithed spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Carvedilol; Decerebrate State; Dos | 1988 |
Antihypertensive therapy in pregnancy directed by noninvasive hemodynamic monitoring.
Topics: Atenolol; Cardiac Output; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Pregnancy; Pregna | 1989 |
Fetal premature atrial contractions associated with hydralazine.
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Echocardiography; Female; Fetal Diseases; Heart Rate; H | 1989 |
Hydralazine, hydrochlorothiazide and ampicillin associated with retroperitoneal fibrosis: case report.
Topics: Adult; Ampicillin; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hype | 1989 |
Coronary vascular function and morphology in hydralazine treated DOCA salt rats.
Topics: Animals; Cardiomegaly; Coronary Vessels; Desoxycorticosterone; Hydralazine; Hypertension; Rats; Rats | 1988 |
Effects of clonidine, alpha-methyldopa and hydralazine on met-enkephalinergic neurons in cerebral nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Enkephalin, Methionine; Fluorescent Antibody Technique; H | 1985 |
Specific increase of hypothalamic alpha 1-adrenoceptors in spontaneously hypertensive rats: effect of hypotensive drug treatment.
Topics: Animals; Brain Chemistry; Hydralazine; Hypertension; Male; Methyclothiazide; Rats; Rats, Inbred SHR; | 1985 |
Therapeutic implications of hypertension-induced glomerular injury. Comparison of enalapril and a combination of hydralazine, reserpine, and hydrochlorothiazide in an experimental model.
Topics: Animals; Enalapril; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulonephritis; Glomerulos | 1985 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chem | 1988 |
Current concepts in treatment of hypertensive emergencies.
Topics: Diazoxide; Drug Therapy, Combination; Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Met | 1986 |
Elevated blood pressure during pregnancy.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Me | 1986 |
The effect of hydralazine on steady-state plasma concentrations of metoprolol in pregnant hypertensive women.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Meto | 1988 |
[Combined antihypertensive pharmacotherapy].
Topics: Adult; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Femal | 1988 |
Alteration in sialidase and other glycosidase activities in the kidney of spontaneously hypertensive rats: persistence after preventive treatment with hydralazine.
Topics: Animals; Blood Pressure; Blood Proteins; Glucosidases; Glycoside Hydrolases; Hydralazine; Hypertensi | 1988 |
Ouabain-induced contraction of vascular smooth muscle in spontaneously hypertensive rats and the effect of hydralazine.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium; Calcium Radioisotopes; Hydralazine; Hypertensi | 1988 |
Cardiovascular effects of the novel arteriovenous dilator agent, flosequinan in conscious dogs and cats.
Topics: Animals; Arteries; Blood Pressure; Cats; Chlorides; Dogs; Heart Rate; Hydralazine; Hypertension; Mal | 1988 |
Effect of captopril and hydralazine on arterial pressure-urinary output relationships in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Captopril; Hydralazine; Hypertension; Kidney; Kidney Concentrating Ability; | 1987 |
Dihydralazine and the uteroplacental blood flow.
Topics: Dihydralazine; Female; Humans; Hydralazine; Hypertension; Placenta; Pregnancy; Pregnancy Complicatio | 1988 |
Hypertensive crisis in L & D.
Topics: Adult; Critical Care; Diazoxide; Female; Humans; Hydralazine; Hypertension; Magnesium Sulfate; Nitro | 1988 |
[Chronic drug-induced hepatitis caused by dihydralazine].
Topics: Aged; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chronic Disease; Dihydralazine; Female | 1988 |
Long-term microvascular response to hydralazine in spontaneously hypertensive rats.
Topics: Animals; Arterioles; Blood Pressure; Catheterization; Heart Rate; Hydralazine; Hypertension; Microci | 1988 |
[Chronotherapy of hypertensive patients].
Topics: Adult; Circadian Rhythm; Drug Therapy, Combination; Heart; Hemodynamics; Humans; Hydralazine; Hypert | 1988 |
System approach to testing hypotensive drugs for prevention of arterial hypertension.
Topics: Clinical Trials as Topic; Humans; Hydralazine; Hyperlipidemias; Hypertension; Prazosin; Propranolol | 1987 |
Effect of antihypertensive therapy on a vascular change in genetically hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniqu | 1987 |
Alterations in calcium-handling of erythrocytes in spontaneously hypertensive rats. Calcium-induced changes in the osmotic fragility of erythrocytes in hypertension.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Erythrocytes; Hydralazine; Hypertension; | 1987 |
[Dihydralazine and intracranial pressure. Risks in the treatment of patients with space-occupying, intracranial processes].
Topics: Aged; Cerebrovascular Circulation; Dihydralazine; Humans; Hydralazine; Hypertension; Intracranial Pr | 1987 |
Establishment and use of the M strain of stroke-prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hydralazin | 1986 |
Side-effects in long-term treatment with hydralazine.
Topics: Aged; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; | 1986 |
Antihypertensive drugs inhibit hypertension-associated aortic DNA synthesis in the rat.
Topics: Animals; Antihypertensive Agents; Captopril; DNA; Female; Hydralazine; Hypertension; Hypertension, R | 1986 |
The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs.
Topics: Acebutolol; Aldosterone; Animals; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Hydrala | 1986 |
Differential structural responses of small resistance vessels to antihypertensive therapy.
Topics: Animals; Antihypertensive Agents; Blood Vessels; Captopril; Hindlimb; Hydralazine; Hydrochlorothiazi | 1987 |
Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Captopril; Hydralazine; Hypertension; Male; Muscle, Smooth, Vascul | 1987 |
Interactions of dihydralazine with furosemide in hypertonic patients.
Topics: Adult; Dihydralazine; Drug Interactions; Female; Furosemide; Half-Life; Humans; Hydralazine; Hyperte | 1987 |
[Efficacy of a graded plan for long-term prevention using antihypertensive drugs. Work Group for the Cooperative Study for the Testing of New Preparations for the Prevention of Arterial Hypertension (CSPPAH)].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Heart Rate; Hum | 1987 |
The use of dihydralazine infusion in the management of severe hypertension in pregnancy.
Topics: Adult; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Infusions, Intravenous; Pregnancy; | 1986 |
Antihypertensive drug therapy prevents cerebral microvascular abnormalities in hypertensive rats.
Topics: Adaptation, Physiological; Animals; Antihypertensive Agents; Blood Flow Velocity; Cerebrovascular Ci | 1987 |
Vascular reactivity in the spontaneously hypertensive stroke-prone rat. Effect of antihypertensive treatment.
Topics: Animals; Blood Pressure; Calcium; Cerebrovascular Disorders; Female; Femoral Artery; Hydralazine; Hy | 1987 |
Metabolism of hydralazine in man. Part II: Investigation of features relevant to drug safety.
Topics: Acetylation; Biotransformation; Female; Humans; Hydralazine; Hypertension; Male; Metabolic Clearance | 1987 |
[Interaction of digoxin with hydralazine and prazosin].
Topics: Adult; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Mal | 1986 |
Laryngeal manifestations of drug induced lupus.
Topics: Female; Hoarseness; Humans; Hydralazine; Hypertension; Laryngeal Diseases; Lupus Erythematosus, Syst | 1987 |
Recent studies on M-SHRSP and their crossbred offspring with WKY.
Topics: Animals; Blood Pressure; Crosses, Genetic; Disease Models, Animal; Female; Hydralazine; Hypertension | 1987 |
Severe hypertension, propranolol, and acute pulmonary edema.
Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Heart Failure; Humans; Hydralazine; Hypertension | 1987 |
Disturbance of acid-base balance in the young spontaneously hypertensive rat.
Topics: Acid-Base Imbalance; Anesthesia, General; Animals; Bicarbonates; Blood Pressure; Calcium; Hydralazin | 1987 |
Acute neutrophilic dermatosis associated with hydralazine-induced lupus.
Topics: Aged; Humans; Hydralazine; Hypertension; Leukocytosis; Lupus Erythematosus, Cutaneous; Male; Neutrop | 1987 |
[Antihypertensive effects of SA446, hydralazine and the combination on renal hypertensive rats and spontaneously hypertensive rats by long-term treatment].
Topics: 3-Mercaptopropionic Acid; Animals; Antihypertensive Agents; Body Weight; Diuresis; Drinking; Drug Th | 1986 |
Fetal distress after hydralazine therapy for severe pregnancy-induced hypertension.
Topics: Acute Disease; Cesarean Section; Eclampsia; Female; Fetal Distress; Gestational Age; Humans; Hydrala | 1986 |
[Effect of an antihypertensive drug, budralazine, on glucose and lipid metabolism in diabetic SHR].
Topics: Animals; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 1986 |
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chorionic Villi; Dihydralazine; Female; Furosem | 1986 |
Ca fluxes across duodenum and colon of spontaneously hypertensive rats: effect of 1,25(OH)2D3.
Topics: Animals; Calcitriol; Calcium; Colon; Duodenum; Electrochemistry; Hydralazine; Hypertension; Male; Ra | 1986 |
Control of hypertension following carotid endarterectomy.
Topics: Aged; Carotid Artery Diseases; Drug Therapy, Combination; Endarterectomy; Humans; Hydralazine; Hyper | 1986 |
[Regional hemodynamic function in chronic obstructive bronchitis with arterial hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bronchitis; Chronic Disease; Female; Hemodynamics; | 1986 |
The effect of hydralazine on placental perfusion in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Female; Hydralazine; Hypertension; Perfusion; Placenta; Pregnancy; | 1987 |
Evaluation of a novel antihypertensive agent, LY127210, in anesthetized and conscious spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relati | 1985 |
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Dihydralazine; Female; Fetal Heart; Humans; Hydralazin | 1985 |
Potential antihypertensives. Synthesis of 6-substituted-N-(4H-1,2,4-triazol-4-yl)-3-pyridazinamines and 3-substituted-6-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)pyridazines.
Topics: Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Hydralazine; Hypertension; Lethal D | 1985 |
[Arterial hypertension in chronic bronchial obstruction and various problems of its treatment].
Topics: Adult; Asthma; Bronchitis; Chronic Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; | 1985 |
Hemodynamic and vascular activity of LY127210, a new vasodilator, in anesthetized spontaneously hypertensive rats: comparison with hydralazine.
Topics: Animals; Antihypertensive Agents; Benzazepines; Hemodynamics; Hydralazine; Hypertension; Male; Rats; | 1985 |
The influence of the acetylator phenotype for the clinical use of dihydralazine.
Topics: Acetylation; Adult; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Phe | 1985 |
Drugs for hypertensive emergencies.
Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertensio | 1985 |
Hydralazine induced lupus syndrome with eye disease.
Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Retinitis; Sy | 1985 |
Effects of felodipine on resistance and capacitance vessels in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Vessels; Electrocardiography; | 1985 |
Lupus after six years of mild hypertension.
Topics: Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Middle Aged; Time Factors | 1985 |
Effects of hydralazine on streptozotocin-induced diabetic rats: prevention of hyperlipidemia and improvement in cardiac function.
Topics: Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Heart Atria; Heart Rate; Hydralaz | 1986 |
Serial measurements of systolic time intervals during treatment with hydrochlorothiazide alone and combined with other antihypertensive agents.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Electrocardiography; Humans; Hydralazine; Hydroc | 1985 |
Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hindlimb; Hydralazine | 1985 |
[Hypotensive effect and tolerability of a short course of treatment with prazosin (pratsiol) and hydralazine (apressin) in a cooperative study of new drugs for the prevention of arterial hypertension].
Topics: Adult; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Midd | 1985 |
Effects of felodipine on renal function in animals.
Topics: Animals; Antihypertensive Agents; Dogs; Felodipine; Glomerular Filtration Rate; Hemodynamics; Hydral | 1985 |
Haemodynamic effects of short and long term administration of felodipine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Cardiac Output; Coronary Circulation; Drug Administration Schedule | 1985 |
Function of the isolated spontaneously hypertensive rat kidney after blood pressure reduction.
Topics: Animals; Blood Pressure; Diazoxide; Drug Evaluation, Preclinical; Hydralazine; Hydrochlorothiazide; | 1985 |
Plasma prolactin concentrations and pregnancy-induced hypertension.
Topics: Adult; Apgar Score; Birth Weight; Circadian Rhythm; Female; Gestational Age; Humans; Hydralazine; Hy | 1985 |
Plasma hydrazine concentrations in man after isoniazid and hydralazine administration.
Topics: Acetylation; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydralazine; Hydrazines; Hypertens | 1985 |
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor | 1985 |
Hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hyp | 1985 |
Cardiovascular alterations in severe pregnancy-induced hypertension seen with an intravenously given hydralazine bolus.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Hydralazine; Hypertension; Pregna | 1985 |
Hemodynamic effects of intravenous hydralazine in pregnant women with severe hypertension.
Topics: Blood Pressure; Body Surface Area; Cardiac Output; Echocardiography; Female; Hemodynamics; Humans; H | 1985 |
[Pharmacological studies on pinacidil, a new anti-hypertensive agent. 1. Antihypertensive effects in SHR and DOC/saline hypertensive rats].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Desoxycorticosterone; Female; Guanidines; Hy | 1985 |
The treatment of mild hypertension in the elderly, a prospective study using multiple regression analysis.
Topics: Aged; Benzothiadiazines; Blood Pressure; Cholesterol; Diuretics; Female; Humans; Hydralazine; Hypert | 1985 |
[Quantitative determination and kinetics of dihydralazine in hypertension patients].
Topics: Acetylation; Adult; Aged; Bile; Dihydralazine; Female; Humans; Hydralazine; Hypertension; Kinetics; | 1985 |
Results of treatment of hypertension.
Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Hum | 1971 |
Immunologic findings in patients receiving methyldopa: a prospective study.
Topics: Acyltransferases; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Autoimmune Diseases; Black Pe | 1971 |
Systemic lupus erythematosus following prolonged treatment with hydralazine.
Topics: Blood Cell Count; Fluorescent Antibody Technique; Hemoglobinometry; Humans; Hydralazine; Hypertensio | 1971 |
Refractory hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Chronic Disease; Diazoxide; Drug Combinations; Drug R | 1973 |
Hypertension 1973: treatment--why and how.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Diure | 1973 |
Management of severe hypertension.
Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intra | 1973 |
[The treatment of arterial hypertension associated with renal insufficiency].
Topics: Clonidine; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Kidney F | 1973 |
[Early therapy of light hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Glycosides; Diet, Sodium-Restricted; Diuretics; Female; | 1973 |
Combined treatment of hypertension with vasodilatation and beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hyperten | 1973 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Ganglionic | 1973 |
[Beta-blockaders in hypertension].
Topics: Adrenergic beta-Antagonists; Alprenolol; Drug Therapy, Combination; Humans; Hydralazine; Hypertensio | 1973 |
[Letter: Diet and drugs in arterial hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Clonidine; Diet, Sodium-Restricted; Diure | 1974 |
[Combination of beta blockaders with vasodilator substances in hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hydralazine | 1974 |
Drug combinations as rational antihypertensive therapy.
Topics: Administration, Oral; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Ganglionic Bloc | 1974 |
[Pharmacology of antihypertensive agents (author's transl)].
Topics: Antihypertensive Agents; Blood Pressure; Bretylium Compounds; Diuretics; Evaluation Studies as Topic | 1974 |
Potentiation of the antihypertensive action of hydralazine by timolol in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Drug Synergism; Heart Rate; Hydralazine; Hyper | 1974 |
[Differential therapeutic principles in the drug therapy of high blood pressure].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Cardiac Vol | 1974 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
[General principles of antihypertensive treatment].
Topics: Antihypertensive Agents; Cardiac Output; Clonidine; Follow-Up Studies; Ganglionic Blockers; Guanethi | 1974 |
Adrenolytic and vasodilator therapy.
Topics: Adrenergic beta-Antagonists; Benzyl Compounds; Blood Circulation; Cardiac Output; Clonidine; Diazoxi | 1974 |
Prevalence and management of hypertension in a general population sample of Swedish men.
Topics: Adrenergic beta-Antagonists; Adult; Bacteriuria; Blood Pressure; Costs and Cost Analysis; Creatinine | 1973 |
[Prolonged administration of hydralazine in the guinea pig. Serologic and clinico-pathologic changes].
Topics: Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Cell Nucleus; Dogs; Female; Fluorescent Ant | 1968 |
Propranolol given twice daily in hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; | 1973 |
[Differential diagnosis and pharmacotherapy of hypertension (author's transl)].
Topics: Arteriosclerosis; Coronary Disease; Diagnosis, Differential; Diuretics; Electrocardiography; Guaneth | 1974 |
[Surgery in hypertension (author's transl)].
Topics: Adrenal Gland Neoplasms; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Pheochromocyto | 1974 |
Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Chlorothiazide; Diuretics | 1974 |
Aspects of the relation between functional and structural cardiovascular factors in primary hypertension. Experimental studies in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Capillary Resistance; Cardiac Output; Cardiomegaly; Coronary Circula | 1974 |
Periodic dialysis in terminal uremia.
Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul | 1967 |
Evaluation of antihypertensive drugs in dogs with angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Female; Hexamethoniu | 1971 |
How an acute rise in arterial pressure damages arterioles. Electron microscopic changes during angiotensin infusion.
Topics: Angiotensin II; Animals; Arteries; Basement Membrane; Blood Platelets; Capillary Permeability; Carbo | 1972 |
Cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Cardiomegaly; DNA; Heart Ventricles; Hydralazine; Hypertension | 1974 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; | 1974 |
Adolescent hypertension. II. Characteristics and response to treatment.
Topics: Adolescent; Adult; Angiotensin II; Black or African American; Female; Humans; Hydralazine; Hypertens | 1974 |
[Hemodynamic regulation of the heart in hypertension under intravenous administration of dihydralazine].
Topics: Angiotensin II; Blood Pressure; Heart; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; | 1974 |
[Drug therapy of hypertension].
Topics: Antihypertensive Agents; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Hyper | 1965 |
Hypertension past 60.
Topics: Aged; Benzothiadiazines; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa | 1967 |
The use and abuse of antihypertensive drugs in the aged.
Topics: Aged; Antihypertensive Agents; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Ph | 1967 |
[The present situation of treatment of hypertension].
Topics: Diagnosis, Differential; Diet Therapy; Diet, Sodium-Restricted; Diuretics; Ganglionic Blockers; Guan | 1967 |
[Principles of hypertension therapy].
Topics: Adult; Antihypertensive Agents; Aortic Valve Stenosis; Brain Neoplasms; Cushing Syndrome; Diagnosis, | 1967 |
Hypotensive drugs. I.
Topics: Antihypertensive Agents; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Methyldo | 1969 |
The medical treatment of hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Diet Therapy; Emergencies; Furosemide; Ganglionic Blockers; | 1970 |
[Anti-hypertensive agents].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diuretics; Ganglionic Blockers; Humans; Hydral | 1969 |
Treatment of hypertensive crisis.
Topics: Adrenergic alpha-Antagonists; Diazoxide; Ethacrynic Acid; Ferricyanides; Furosemide; Humans; Hydrala | 1970 |
[Drug therapy of hypertension].
Topics: Digitalis Glycosides; Dihydroxyphenylalanine; Diuretics; Ganglionic Blockers; Humans; Hydralazine; H | 1971 |
[Therapy of arterial hypertension. Results, possibilities, methods].
Topics: Adrenergic beta-Antagonists; Cerebrovascular Circulation; Coronary Disease; Diet; Diuretics; Electri | 1970 |
Combined therapy with vasodilator drugs and beta-adrenergic blockade in hypertension. A comparative study of minoxidil and hydralazine.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Body Weight; Cardiac Output; Female; Fu | 1972 |
Treatment of essential hypertension with combined vasodilation and beta-adrenergic blockade.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Diuretics; Female; G | 1972 |
Drug therapy in hypertension.
Topics: Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Monoami | 1971 |
[Beta blockaders and hydralazine. A promising new combination for hypertension].
Topics: Adrenergic beta-Antagonists; Drug Combinations; Humans; Hydralazine; Hypertension; Sympatholytics | 1972 |
Drugs used in the treatment of hypertension. 2.
Topics: Ganglionic Blockers; Hydralazine; Hypertension; Monoamine Oxidase Inhibitors; Phytotherapy; Plants, | 1972 |
Antihypertensive activity of four blocking agents in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Blood Pressure; Clonidine | 1972 |
Beta-blocking therapy: Propranolol.
Topics: Cardiac Output; Central Nervous System; Drug Therapy, Combination; Furosemide; Humans; Hydralazine; | 1974 |
Dialysis and volume control.
Topics: Humans; Hydralazine; Hypertension; Minoxidil; Nephrectomy; Propranolol; Renal Dialysis; Sodium; Ultr | 1974 |
Hypertension as a clinical problem: the hospital based population.
Topics: Adult; Age Factors; Antihypertensive Agents; Black People; Blood Pressure Determination; Camphor; Di | 1974 |
Office management of hypertension.
Topics: Adult; Aged; Ambulatory Care; Drug Therapy, Combination; Female; Follow-Up Studies; Furosemide; Guan | 1974 |
Editorial: The hypertensive patient.
Topics: Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Reserpine | 1974 |
Essential hypertension in adolescents.
Topics: Adolescent; Adult; Antihypertensive Agents; Child; Contraceptives, Oral, Synthetic; Diet, Sodium-Res | 1974 |
Practical office management of chronic hypertension.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochloroth | 1974 |
Anaesthesia for coarctation. A new classification for rational anaesthetic management.
Topics: Anesthesia, General; Aortic Coarctation; Blood Pressure; Chlorpromazine; Collateral Circulation; Fem | 1974 |
Antihypertensive activity of 1-(2-(1,3-dimethyl-2-butenylidene)-hydrazino)-phthalazine (DJ-1461), a new phthalazine derivative.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Ra | 1974 |
[Indications of antihypertensive treatment in non-malignant hypertension].
Topics: Antihypertensive Agents; Aortic Aneurysm; Benzothiadiazines; Cerebrovascular Disorders; Coronary Dis | 1974 |
[Recent viewpoints on the metablism of hydralazine].
Topics: Acetylation; Humans; Hydralazine; Hypertension | 1974 |
Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat.
Topics: Animals; Antihypertensive Agents; Cats; Cellophane; Clonidine; Corticosterone; Delayed-Action Prepar | 1974 |
[Possibilities and limitations of hypertensive therapy].
Topics: Clonidine; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; R | 1974 |
[Treatemtn of arterial hypertension with the combination of hydralazine and propranolol].
Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; M | 1974 |
[Treatment of arterial hypertension with the combination of hydralazine and propranolol].
Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; M | 1974 |
[Pregnancy toxemia. Mechanism, prevention and treatment].
Topics: Blood Coagulation Disorders; Diet, Sodium-Restricted; Diuretics; Eclampsia; Edema; Female; Hospitali | 1974 |
The effect of prostaglandin E2 on the arterial blood pressure of normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, | 1974 |
Dietary sodium restriction and natriuresis in management of hypertension.
Topics: Adult; Aged; Benzothiadiazines; Diet, Sodium-Restricted; Diuretics; Ethacrynic Acid; Female; Furosem | 1974 |
[The propranolol-dihydralazine combination in the therapy of systemic arterial hypertension].
Topics: Adult; Drug Combinations; Drug Evaluation; Female; Humans; Hydralazine; Hypertension; Male; Middle A | 1974 |
Hypertension.
Topics: Antihypertensive Agents; Blood Pressure Determination; Cerebrovascular Disorders; Diuretics; Drug Co | 1974 |
Aggressive drug therapy in accelerated hypertension.
Topics: Antihypertensive Agents; Aortic Aneurysm; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Ferr | 1974 |
Immune responses to hydralazine and nuclear antigens in hydralazine-induced lupus erythematosus.
Topics: Adult; Antibodies, Antinuclear; Antibody Formation; Complement Fixation Tests; DNA; Drug Hypersensit | 1972 |
Renal cortical blood flow, cortical fraction, and cortical blood volume in hypertensive subjects.
Topics: Adult; Blood Flow Velocity; Blood Urea Nitrogen; Creatinine; Female; Guanethidine; Hematocrit; Human | 1973 |
[Frequency of hematologic side effects in antihypertensive long-term therapy].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antihypertensive Agents; Arteriosclerosis; Blood C | 1973 |
[Pnopanolol in a 2 dose regimen in cases of hypertension].
Topics: Administration, Oral; Adult; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranol | 1972 |
[A difficult diagnosis?].
Topics: Aged; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans; Hydralazine; Hypertension; Lup | 1972 |
[Arterial hypertension in elderly persons].
Topics: Aged; Central Nervous System Diseases; Coronary Disease; Humans; Hydralazine; Hypertension; Kidney D | 1972 |
The management of hypertension during pregnancy.
Topics: Adolescent; Adult; Blood Pressure; Clinical Laboratory Techniques; Diagnosis, Differential; Dihydrox | 1972 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Minoxidil in severe hypertension with renal failure. Effect of its addition to conventional antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Evaluation Studies as Topic; Female; Follow-Up Studi | 1973 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic | 1973 |
How to treat arterial hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; | 1973 |
Hydralazine disease associated with transient granulomas in the liver. A case report.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Female; Granuloma; Humans; Hydralazine; Hypertension | 1973 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; | 1973 |
[Evaluation of antihypertensive therapy with Adelphan-Esidrex by clinical and psychometric parameters].
Topics: Adult; Aged; Blood Pressure; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hy | 1973 |
Drug failure in reducing pressor effect of isometric handgrip stress test in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Electrocardiogra | 1973 |
[Electrolyte metabolism in patients with hypertensive disease treated with hyparez].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothi | 1973 |
Influence of guanethidine on the cerebrospinal fluid and blood catecholamines in essential hypertension.
Topics: Catecholamines; Guanethidine; Humans; Hydralazine; Hypertension | 1973 |
Fluorescein circulation time and the treatment of hypertension in the aged.
Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Femal | 1973 |
[Plasma renin activity in venous renal blood and its stimulation by hydralazine and theophylline (author's transl)].
Topics: Blood Pressure; Chemoreceptor Cells; Humans; Hydralazine; Hypertension; Hypertension, Renal; Juxtagl | 1973 |
[Antihypertensive agents. Interesting results with rats].
Topics: Age Factors; Animals; Chlorothiazide; Humans; Hydralazine; Hypertension; Rats; Reserpine; Time Facto | 1973 |
Drugs used in the treatment of hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ethacrynic Acid; Fer | 1973 |
Hypertensive encephalopathy following urological surgery.
Topics: Atropine; Blood Urea Nitrogen; Brain Diseases; Chlorides; Creatinine; Fever; Halothane; Humans; Hydr | 1973 |
[Hypertensive leg ulcer--myth or reality?].
Topics: Aged; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Leg Ulcer; Male; Methyldop | 1973 |
[Renin activity in renal vein blood and its stimulation by various drugs].
Topics: Humans; Hydralazine; Hypertension; Hypertension, Renal; Renal Veins; Renin; Theophylline | 1973 |
Identification of 3-methyl-s-triazolo(3,4-alphathalazine, a human hydralazine metabolite, by gas chromatography-mass spectrometry.
Topics: Adult; Chromatography, Gas; Heterocyclic Compounds; Humans; Hydralazine; Hypertension; Mass Spectrom | 1973 |
Onthe pharmacology of 3-hydrazino-6-(N,N-bis(2-hydroxyethyl)amino)-pyridazine-dihydrochloride (L 6150).
Topics: Animals; Blood Pressure; Cardiac Output; Decerebrate State; Dogs; Ethanolamines; Female; Hydralazine | 1973 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therap | 1973 |
[New trends in the diagnosis, prognosis and treatment of hypertension].
Topics: Dexamethasone; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Prognosis; Propranolol; | 1974 |
Long-term treatment with antihypertensive drugs in spontaneously hypertensive rats (SHR). Effects on blood pressure, survival rate and cardiovascular design.
Topics: Age Factors; Animals; Blood Pressure; Depression, Chemical; Female; Guanethidine; Heart; Hydralazine | 1974 |
"Hantzsch-type" dihydropyridine hypotensive agents. 3.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Cats; Central Nervous System; De | 1974 |
Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine.
Topics: Acyltransferases; Adult; Antibodies, Antinuclear; Female; Fluorescent Antibody Technique; Humans; Hy | 1970 |
Observation on the mechanism of renin release by hydralazine in hypertensive patients.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Hemodynamics; | 1970 |
Galactorrhea and Parkinson-like syndrome: an adverse effect of alpha-methyldopa.
Topics: Adolescent; Amenorrhea; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Kidney Transp | 1970 |
[What is reliable in the therapy of hypertension?].
Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health | 1970 |
[Hemodynamic basis of the medical treatment of arterial hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Diuretics; Female; Guanethidine; Hem | 1971 |
Antinuclear antibodies following hydralazine toxicity.
Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Drug Hypersensitivity; Female; Humans; Hydrala | 1967 |
The effects of vasoactive drugs on the retinal circulation.
Topics: Bis-Trimethylammonium Compounds; Bromides; Ergoloid Mesylates; Heparin; Hydralazine; Hypertension; N | 1966 |
Treatment of hypertension with Ser-Ap-Es.
Topics: Adult; Aged; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Rese | 1967 |
[A case of lethal vasculitis in a patient treated for hypertension and neurofibromatosis].
Topics: Adult; Arteritis; Autopsy; Hepatic Artery; Humans; Hydralazine; Hypertension; Male; Neurofibromatosi | 1969 |
Hypertension in infantile polycystic renal disease. The importance of early recognition and treatment of severe hypertension in polycystic renal disease.
Topics: Aluminum; Child, Preschool; Glomerular Filtration Rate; Humans; Hydralazine; Hydroxides; Hypertensio | 1972 |
[Treatment of hypertension with high doses of oxprenolol alone or in combination with the vasodilator dihydralazine].
Topics: Amino Alcohols; Cardiac Output; Diuretics; Drug Synergism; Humans; Hydralazine; Hypertension; Oxpren | 1972 |
Alteration of the course of hypertension in the spontaneously hypertensive rat.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorothiazide; Environment; E | 1972 |
Pulmonary infiltrations during dihydralazine treatment in a slow isoniazid-inactivator.
Topics: Diagnosis, Differential; Half-Life; Humans; Hydralazine; Hypertension; Isoniazid; Lung; Lung Disease | 1972 |
[Antihypertensive therapy].
Topics: Adult; Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Female; Humans; Hydralazine | 1972 |
The syndrome of "mesenteric arteritis" following surgical repair of aortic coarctation. Report of nine cases and review of the literature.
Topics: Antihypertensive Agents; Aortic Coarctation; Arteritis; Child; Child, Preschool; Female; Humans; Hyd | 1972 |
Hypercalcemia associated with hypertension due to prolonged immobilization. (An unusual complication of extensive burns).
Topics: Burns; Cerebrospinal Fluid Proteins; Child; Humans; Hydralazine; Hypercalcemia; Hypertension; Immobi | 1972 |
Hypertensive emergencies.
Topics: Diazoxide; Emergencies; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension | 1972 |
[Effect of dihydralazine on renin activity in hypertensive patients].
Topics: Adult; Female; Humans; Hydralazine; Hypertension; Kidney Diseases; Male; Middle Aged; Renal Artery O | 1972 |
[Hypertension].
Topics: Aged; Allopurinol; Antihypertensive Agents; Benzothiadiazines; Chlordiazepoxide; Chlorthalidone; Dia | 1971 |
Intracerebral hemorrhage, acute hydrocephalus, and systemic hypertension.
Topics: Arteriovenous Malformations; Carotid Arteries; Cerebral Hemorrhage; Cerebral Ventriculography; Cereb | 1971 |
The effect of intense treatment with hypotensive drugs on structural design of the resistance vessels in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Guanethidine; Hydralazine; Hypertension; Rats; Vascular Resistance | 1971 |
[Effects of Inderal in the treatment of uremic hypertension].
Topics: Adult; Allopurinol; Diabetic Coma; Drug Combinations; Drug Interactions; Female; Humans; Hydralazine | 1971 |
Coexistent trophoblastic tumor and viable pregnancy.
Topics: Adult; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Hydralazine; Hype | 1971 |
Drug therapy of hypertension.
Topics: Blood Pressure; Blood Urea Nitrogen; Chlorothiazide; Humans; Hydralazine; Hypertension; Hypnotics an | 1971 |
[Treatment of hypertension with alprenolol and hydralazine].
Topics: Aged; Amino Alcohols; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; | 1971 |
[Hypertension therapy with propanolol and hydralazine].
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Propranol | 1971 |
Treatment of hypertension with propranolol and hydralazine.
Topics: Adult; Creatinine; Drug Interactions; Fatigue; Female; Humans; Hydralazine; Hypertension; Male; Midd | 1971 |
Hemodynamic interference of alprenolol with dihydralazine in normal and hypertensive man.
Topics: Adult; Alprenolol; Cardiac Output; Cardiac Volume; Drug Interactions; Female; Heart Rate; Hemodynami | 1971 |
[On a new hypotensive pharmacological association in pregnancy with hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Carbamates; Creatinine; Electrolytes; Female; Humans | 1971 |
Some effects of hydralazine on hypertensive patients with impaired kidney function.
Topics: Animals; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension; Injections, Intravenous; Kid | 1968 |
Clinical and laboratory observations on eclampsia.
Topics: Blood Chemical Analysis; Blood Volume Determination; Cesarean Section; Delivery, Obstetric; Eclampsi | 1967 |
Heterocyclic systems with a bridgehead nitrogen. II. 6-Chloroimidazo[2,1-b]thiazole and some of its 5-substituted derivatives.
Topics: Animals; Aspirin; Blood Pressure; Chemical Phenomena; Chemistry; Enterobacteriaceae; Female; Fungi; | 1969 |
2,6-Dichlorobenzylidene amino guanidine acetate (Wy-8678). A new hypotensive agent.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Female; Guanethidine; Guan | 1969 |
[Maximum consumption of oxygen and work capacity in patients with essential arterial hypertension after treatment].
Topics: Adolescent; Adult; Disability Evaluation; Exercise Test; Female; Heart; Humans; Hydralazine; Hydroch | 1969 |
Escape from sodium-retaining effects of deoxycorticosterone in hypotensive and hypertensive dogs.
Topics: Aminohippuric Acids; Animals; Blood Pressure; Creatinine; Desoxycorticosterone; Dogs; Ephedrine; Fem | 1970 |
Vasodilation in treatment of hypertension.
Topics: Humans; Hydralazine; Hypertension; Piperidines; Propranolol; Pyrimidines; Vasodilator Agents | 1970 |
Vasodilation in treatment of hypertension.
Topics: Humans; Hydralazine; Hypertension; Piperidines; Propranolol; Pyrimidines; Vasodilator Agents | 1970 |
Comparative effects of currently available antihypertensive agents on spontaneously and renal hypertensive rats.
Topics: Animals; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hydralazine; Hypertension; Hypertens | 1970 |
Influence of extracellular fluid volume on response to antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Cardiac Output; Central Venous Pressure; Diazoxide; Drug Sy | 1970 |
[Hydralazine syndrome].
Topics: Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Hypotension, Orthostatic; Joint Diseases | 1970 |
[Effect of long-term treatment with antihypertensive drugs on clinical and pathological states and analysis of cause of death in hypertensive subjects].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Electrocardiography; Female; Humans; Hydralazi | 1970 |
[Medical treatment of arterial hypertension: hemodynamic study].
Topics: Adult; Cardiac Output; Diuretics; Drug Synergism; Female; Guanethidine; Hemodynamics; Humans; Hydral | 1970 |
[Therapy of hypertension].
Topics: Adrenal Gland Neoplasms; Aniline Compounds; Antihypertensive Agents; Diuretics; Female; Guanethidine | 1971 |
Relationship of extracellular fluid volume to the development of drug resistance in the hypertensive patient.
Topics: Antihypertensive Agents; Diazoxide; Diuretics; Drug Synergism; Drug Tolerance; Extracellular Space; | 1971 |
[Medical treatment of arterial hypertension. Clinical study].
Topics: Adult; Antihypertensive Agents; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hypertension; | 1971 |
[Medical treatment of arterial hypertension: hemodynamic study].
Topics: Adult; Antihypertensive Agents; Cardiac Output; Chlorothiazide; Diuretics; Female; Hemodynamics; Hum | 1971 |
Orthostatic hypertension following brain trauma: report of a case.
Topics: Adolescent; Brain Edema; Brain Injuries; Follow-Up Studies; Guanethidine; Hematoma, Subdural; Humans | 1971 |
Hypotensive action from combination of propranolol and other hypotensive drugs.
Topics: Antihypertensive Agents; Drug Synergism; Exercise Therapy; Guanethidine; Humans; Hydralazine; Hypert | 1971 |
Hypertensive crisis.
Topics: Administration, Oral; Adolescent; Aged; Diazoxide; Diuretics; Female; Humans; Hydralazine; Hypertens | 1971 |
[Results of combined therapy (Adelphan-Esidrix and Ismelin) in severe hypertension].
Topics: Antihypertensive Agents; Drug Synergism; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hyp | 1967 |
Healing and exacerbation of arterial lesions in rats with experimental hypertension, with special reference to effects of antihypertensive drugs on arterial lesions.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Cerebral Arteries; Cerebral Hemorrhage; | 1967 |
[Recent progress in the knowledge of arterial hypertension. VII. Acute effects of antihypertensive drugs on kidney function].
Topics: Acute Disease; Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertensi | 1967 |
[Drug therapy of hypertension].
Topics: Adult; Aged; Diet Therapy; Diuretics; Enzyme Repression; Guanidines; Humans; Hydralazine; Hypertensi | 1967 |
[Clinical picture and therapy of hypertension].
Topics: Adult; Aged; Blood Pressure; Diagnosis, Differential; Diet Therapy; Diet, Sodium-Restricted; Drug Sy | 1967 |
[Results of hypotensive treatment in a hospital environment].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hyperte | 1968 |
Management of severe hypertension with a combination of Adelphane-Esidrex and guanethidine sulphate (Ismelin).
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Female; Guanethidine; Humans; Hydralazine; Hydroch | 1968 |
[Treatment of stenocardia in hypertension].
Topics: Angina Pectoris; Anticoagulants; Humans; Hydralazine; Hypertension; Iproniazid; Reserpine | 1968 |
Hydralazine and plasma renin activity.
Topics: Adolescent; Adult; Blood Pressure; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Heart R | 1968 |
[May medical therapy of arterial hypertension by used in patients with renal failure?].
Topics: Antihypertensive Agents; Diazoxide; Drug Tolerance; Guanethidine; Humans; Hydralazine; Hypertension; | 1968 |
[Objectives and methods in therapy of essential arterial hypertension].
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazi | 1968 |
Furosemide in the treatment of acute post-streptococcal glomerulonephritis.
Topics: Bicarbonates; Blood Pressure Determination; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Edema | 1969 |
An approach to the medical treatment of hypertension in the aged.
Topics: Age Factors; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Diuretics; | 1969 |
Management of hypertension. Treatment of hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Humans; Hydralazine; Hypertension; Methyldopa; Reserpine | 1969 |
[Considerations on ambulatory therapy in a group of hypertensive patients].
Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothia | 1969 |
Essential hypertension--effective therapy in private practice.
Topics: Adult; Aged; Antihypertensive Agents; Drug Synergism; Female; Humans; Hydralazine; Hydrochlorothiazi | 1969 |
Hypertensive crisis.
Topics: Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Reserpine; | 1969 |
Hypotensive drug therapy in the management of hypertension.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methy | 1969 |
Hypotensive actions of drugs on unanesthetized normotensive and "metacorticoid" hypertensive rats determined by a direct recording technique.
Topics: Animals; Antihypertensive Agents; Carbamates; Chlorisondamine; Desoxycorticosterone; Diazoxide; Guan | 1965 |
Pyridoxine-deficiency neuropathy due to hydralazine.
Topics: Female; Humans; Hydralazine; Hypertension; Middle Aged; Paresthesia; Pyridoxine; Tryptophan; Urine; | 1965 |
Clinical rounds from the Massachusetts General Hospital. Childhood hypertension: etiology, investigation and treatment.
Topics: Adolescent; Adrenal Gland Neoplasms; Aortic Coarctation; Child; Child, Preschool; Cushing Syndrome; | 1966 |
The pharmacology and clinical use of rauwolfia, hydralazine, thiazides, and aldosterone antagonists in arterial hypertension.
Topics: Aldosterone; Benzothiadiazines; Diuretics; Humans; Hydralazine; Hypertension; Phytotherapy; Plants, | 1966 |
[Clinical trials of a new antihypertensive drug association in aged subjects. Behavior of the electrolyte pattern].
Topics: Aged; Carbamates; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Potassium Ch | 1966 |
Essential hypertension complicating pregnancy: Factors affecting the fetal mortality.
Topics: Adult; Female; Fetal Death; Humans; Hydralazine; Hypertension; Middle Aged; Pregnancy; Pregnancy Com | 1966 |
Renal pharmacodynamics of antihypertensive drugs: clinical applications.
Topics: Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hypertension; Kidney Diseases; Methyl | 1966 |
Studies on the control of hypertension. 8. Mortality, morbidity, and remissions during twelve years of intensive therapy.
Topics: Chlorisondamine; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Mecamylam | 1966 |
[The treatment of hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronar | 1966 |
[How can the difficulties in the antihypertensive therapy of prolonged pregnancy be prevented?].
Topics: Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Phytotherapy; Plants, Med | 1966 |
[The drug therapy of hypertension].
Topics: Antihypertensive Agents; Diet Therapy; Dihydroxyphenylalanine; Diuretics; Humans; Hydralazine; Hyper | 1966 |
[Value of the combination of a heterocyclic tertiary amine (pempidine) and a substituted hydralazine (hydracarbazine) in the ambulatory treatment of arterial hypertension].
Topics: Aged; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Pempidine | 1966 |