Page last updated: 2024-10-28

hydralazine and Atherosclerosis

hydralazine has been researched along with Atherosclerosis in 9 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"Aliskiren reduced the atherosclerotic plaque area and plaque neovessel density."1.40Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques. ( Cheng, XW; Hamrah, MS; Hao, CN; Hayashi, M; Hu, L; Kuzuya, M; Murohara, T; Shi, GP; Takeshita, K; Wu, H, 2014)
"Hydralazine pretreatment reversed DE-induced TF, tPA, TNF-α, and MMP-2 expression but not eNOS, RAGE, and HMGB-1."1.39Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention. ( Andrews, D; Bass, V; Gilmour, MI; King, C; Kodavanti, UP; Krantz, QT; Ledbetter, AD; Nyska, A; Richards, JE; Schladweiler, MC; Thomas, RF, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kodavanti, UP1
Thomas, RF1
Ledbetter, AD1
Schladweiler, MC1
Bass, V1
Krantz, QT1
King, C1
Nyska, A1
Richards, JE1
Andrews, D1
Gilmour, MI1
Wu, H1
Cheng, XW1
Hu, L1
Hao, CN1
Hayashi, M1
Takeshita, K1
Hamrah, MS1
Shi, GP1
Kuzuya, M1
Murohara, T1
Cassis, LA1
Gupte, M1
Thayer, S1
Zhang, X1
Charnigo, R1
Howatt, DA1
Rateri, DL1
Daugherty, A1
Bouguerne, B1
Belkheiri, N1
Bedos-Belval, F1
Vindis, C2
Uchida, K2
Duran, H1
Grazide, MH2
Baltas, M1
Salvayre, R2
Nègre-Salvayre, A2
Suganuma, E2
Zuo, Y2
Ayabe, N2
Ma, J1
Babaev, VR2
Linton, MF2
Fazio, S2
Ichikawa, I2
Fogo, AB2
Kon, V2
Escargueil-Blanc, I1
Elbaz, M1
Marcheix, B1
Motojima, M1
Ikeda, F1
Azuma, K1
Ogihara, T1
Toyofuku, Y1
Otsuka, A1
Mita, T1
Hirose, T1
Tanaka, Y1
Kawamori, R1
Watada, H1
Burcham, PC1
Kaminskas, LM1
Tan, D1
Pyke, SM1

Reviews

1 review available for hydralazine and Atherosclerosis

ArticleYear
Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury.
    Mini reviews in medicinal chemistry, 2008, Volume: 8, Issue:4

    Topics: Acrolein; Alzheimer Disease; Animals; Atherosclerosis; Cell Death; Free Radical Scavengers; Humans;

2008

Other Studies

8 other studies available for hydralazine and Atherosclerosis

ArticleYear
Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention.
    Toxicology and applied pharmacology, 2013, Apr-15, Volume: 268, Issue:2

    Topics: Albumins; Animals; Atherosclerosis; Cardiovascular Diseases; Hydralazine; Hypertension; Lung Disease

2013
Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques.
    Atherosclerosis, 2014, Volume: 237, Issue:2

    Topics: Amides; Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carrier

2014
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Ath

2009
Antiatherogenic effect of bisvanillyl-hydralazone, a new hydralazine derivative with antioxidant, carbonyl scavenger, and antiapoptotic properties.
    Antioxidants & redox signaling, 2011, Volume: 14, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chelating Agents;

2011
Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atherosclerosis; Choleste

2006
Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers.
    Circulation research, 2006, Mar-31, Volume: 98, Issue:6

    Topics: Aldehydes; Animals; Atherosclerosis; Cells, Cultured; DNA; Hydralazine; Hydrazines; Lipoproteins, LD

2006
Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:8

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aortic Di

2007
Angiotensin II type 1 receptor blocker reduces monocyte adhesion to endothelial cells in spontaneously hypertensive rats.
    Endocrine journal, 2007, Volume: 54, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen

2007