hydralazine has been researched along with Aortic Incompetence in 29 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sudden withdrawal of oral therapy with hydralazine for reduction of afterload in a patient precipitated severe congestive heart failure." | 7.66 | Precipitation of heart failure following sudden withdrawal of hydralazine. ( Black, JR; Mehta, J, 1979) |
| "Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator." | 6.36 | Hydralazine in heart failure. ( Chatterjee, K, 1983) |
| "Sudden withdrawal of oral therapy with hydralazine for reduction of afterload in a patient precipitated severe congestive heart failure." | 3.66 | Precipitation of heart failure following sudden withdrawal of hydralazine. ( Black, JR; Mehta, J, 1979) |
| "Hydralazine-treated patients also had significant decreases in LV end-diastolic and end-systolic volume indexes, and a significant increase in ejection fraction." | 2.67 | Effects of long-term vasodilator therapy on electrocardiographic abnormalities in chronic aortic regurgitation. ( Bristow, JD; Cheitlin, M; Greenberg, B; Jacobson, N; Massie, B; Perlmutter, N; Siemienczuk, D; Szlachcic, J; Wilson, R, 1991) |
| "Hydralazine every 8 hr was associated with side effects in 25% to 86% of patients, but when the drug was given every 12 hr it was associated with side effects in only 5% to 19% of patients (p less than ." | 2.66 | Importance of internal controls, statistical methods, and side effects in short-term trials of vasodilators: a study of hydralazine kinetics in patients with aortic regurgitation. ( Chandraratna, PA; Elkayam, U; Kawanishi, DT; McKay, CR; Nana, M; Rahimtoola, SH; Weiss, JN, 1985) |
| "Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator." | 2.36 | Hydralazine in heart failure. ( Chatterjee, K, 1983) |
| "The effect on myocardial function and structure of long-term administration of quinapril (10-20 mg daily), an angiotensin-converting-enzyme (ACE) inhibitor, was investigated in 24 patients (18 men, 6 women; mean age 48 [20-65] years) with chronic isolated asymptomatic aortic or mitral regurgitation." | 1.29 | [Long-term treatment with quinapril in chronic aortic and mitral insufficiency]. ( Schömig, A; Schön, HR, 1995) |
| "Symptomatic patients with chronic aortic regurgitation should undergo aortic valve replacement." | 1.27 | When to intervene in chronic aortic regurgitation. ( Gaasch, WH; Hoshino, PK, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (72.41) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shah, RM | 1 |
| Singh, M | 1 |
| Bhuriya, R | 1 |
| Molnar, J | 1 |
| Arora, RR | 1 |
| Khosla, S | 1 |
| Chatterjee, K | 2 |
| Greenberg, BH | 5 |
| Rahimtoola, SH | 7 |
| Sterz, H | 1 |
| Elkayam, U | 2 |
| McKay, CR | 2 |
| Weber, L | 1 |
| Eisenberg, D | 1 |
| Cohn, JN | 1 |
| Rouleau, JL | 1 |
| Massie, BM | 1 |
| Lanas, F | 1 |
| Stokins, B | 1 |
| Saavedra, J | 1 |
| Opazo, JA | 1 |
| Salvatici, R | 1 |
| Schulthess, L | 1 |
| DeMots, H | 2 |
| Murphy, E | 2 |
| Rahimtoola, S | 1 |
| Schön, HR | 1 |
| Schömig, A | 1 |
| Lin, M | 1 |
| Chiang, HT | 1 |
| Lin, SL | 1 |
| Chang, MS | 1 |
| Chiang, BN | 1 |
| Kuo, HW | 1 |
| Cheitlin, MD | 1 |
| Hoffmann, U | 1 |
| Frank, H | 1 |
| Stefenelli, T | 1 |
| Kaiser, B | 1 |
| Klaar, U | 1 |
| Globits, S | 1 |
| Black, JR | 1 |
| Mehta, J | 1 |
| Nauman, D | 1 |
| Greenberg, B | 3 |
| Massie, B | 3 |
| Bristow, JD | 3 |
| Cheitlin, M | 3 |
| Wilson, R | 1 |
| Perlmutter, N | 1 |
| Jacobson, N | 1 |
| Siemienczuk, D | 2 |
| Szlachcic, J | 2 |
| Dumesnil, JG | 1 |
| Tran, K | 1 |
| Dagenais, GR | 1 |
| Crawford, MH | 1 |
| Wilson, RS | 1 |
| O'Rourke, RA | 1 |
| Vittitoe, JA | 1 |
| Topic, N | 1 |
| Wilson, RA | 1 |
| Thomas, D | 1 |
| Lavítola, Pde L | 1 |
| de Moraes, AV | 1 |
| Dallan, L | 1 |
| Grinberg, M | 1 |
| Sosa, EA | 1 |
| Higa, SS | 1 |
| Bessegato, L | 1 |
| Pileggi, F | 1 |
| Florenzano, F | 1 |
| Solé, C | 1 |
| Escobar, E | 2 |
| Morales, B | 1 |
| Kleaveland, JP | 1 |
| Reichek, N | 1 |
| McCarthy, DM | 1 |
| Chandler, T | 1 |
| Priest, C | 1 |
| Muhammed, A | 1 |
| Makler, PT | 1 |
| Hirshfeld, J | 1 |
| Jebavý, P | 1 |
| Koudelková, E | 1 |
| Jandová, R | 1 |
| Frídl, P | 1 |
| Nana, M | 1 |
| Kawanishi, DT | 1 |
| Chandraratna, PA | 1 |
| Weiss, JN | 1 |
| Jalil, J | 1 |
| Thumala, A | 1 |
| Domenech, R | 1 |
| Venegas, P | 1 |
| Hoshino, PK | 1 |
| Gaasch, WH | 1 |
4 reviews available for hydralazine and Aortic Incompetence
| Article | Year |
|---|---|
Favorable effects of vasodilators on left ventricular remodeling in asymptomatic patients with chronic moderate-severe aortic regurgitation and normal ejection fraction: a meta-analysis of clinical trials.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic Valve Insufficiency; Calci | 2012 |
Hydralazine in heart failure.
Topics: Animals; Aortic Valve Insufficiency; Cardiac Output; Cats; Coronary Circulation; Exercise Test; Hear | 1983 |
Vasodilator therapy of congestive heart failure.
Topics: Aortic Valve Insufficiency; Captopril; Dobutamine; Heart Failure; Humans; Hydralazine; Isosorbide Di | 1980 |
Vasodilator therapy in chronic severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Digitalis Glycosides; Echocardiography; Hemodynamics; H | 1990 |
7 trials available for hydralazine and Aortic Incompetence
| Article | Year |
|---|---|
Vasodilator therapy in chronic asymptomatic aortic regurgitation: enalapril versus hydralazine therapy.
Topics: Aged; Aortic Valve Insufficiency; Chronic Disease; Double-Blind Method; Echocardiography; Enalapril; | 1994 |
Effects of long-term vasodilator therapy on electrocardiographic abnormalities in chronic aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Cardiac Volume; Chronic Disease; Double-Blind Method; Electrocard | 1991 |
Effect of digoxin and vasodilators on left ventricular function in aortic regurgitation.
Topics: Adult; Analysis of Variance; Aortic Valve Insufficiency; Digoxin; Echocardiography; Exercise Test; H | 1989 |
Long-term vasodilator therapy of chronic aortic insufficiency. A randomized double-blinded, placebo-controlled clinical trial.
Topics: Administration, Oral; Adult; Aortic Valve Insufficiency; Blood Volume; Clinical Trials as Topic; Dia | 1988 |
[Comparative study of vasodilator drugs in heart valve diseases].
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Clinical Trials as Topic; Echocardiography; Female; H | 1987 |
Effects of six-month afterload reduction therapy with hydralazine in chronic aortic regurgitation.
Topics: Adult; Aged; Aortic Valve; Aortic Valve Insufficiency; Clinical Trials as Topic; Echocardiography; E | 1986 |
Importance of internal controls, statistical methods, and side effects in short-term trials of vasodilators: a study of hydralazine kinetics in patients with aortic regurgitation.
Topics: Adult; Aged; Aortic Valve Insufficiency; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 1985 |
18 other studies available for hydralazine and Aortic Incompetence
| Article | Year |
|---|---|
Long-term vasodilator therapy in aortic insufficiency. Evidence for regression of left ventricular dilatation and hypertrophy and improvement in systolic pump function.
Topics: Aortic Valve Insufficiency; Cardiac Catheterization; Cardiomegaly; Female; Humans; Hydralazine; Midd | 1980 |
[Causes of acute valve-conditioned left ventricular insufficiency-- attempt at a tabulated review].
Topics: Aortic Valve Insufficiency; Cardiac Glycosides; Dyspnea; Endocarditis, Bacterial; Humans; Hydralazin | 1984 |
Favorable effects of hydralazine on the hemodynamic response to isometric exercise in chronic severe aortic regurgitation.
Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; H | 1984 |
Usefulness of vasodilator therapy in acute and chronic valvular regurgitation.
Topics: Aortic Valve; Aortic Valve Insufficiency; Combined Modality Therapy; Digoxin; Drug Therapy, Combinat | 1984 |
Hydralazine in chronic CHF.
Topics: Administration, Oral; Aortic Valve Insufficiency; Cardiac Output; Chronic Disease; Drug Therapy, Com | 1981 |
[Hydralazine in patients with severe aortic insufficiency. Effect on ventricular pressure and volume].
Topics: Adult; Aortic Valve Insufficiency; Cardiac Volume; Echocardiography; Exercise Test; Heart Ventricles | 1982 |
Vasodilator therapy for valvular heart disease.
Topics: Aortic Valve Insufficiency; Cardiac Output, Low; Heart Valve Diseases; Hemodynamics; Humans; Hydrala | 1981 |
Beneficial effects of hydralazine on rest and exercise hemodynamics in patients with chronic severe aortic insufficiency.
Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Chronic Disease; Exercise Test; Female; Hea | 1980 |
Mechanism for improved cardiac performance with arteriolar dilators in aortic insufficiency.
Topics: Adult; Aged; Aortic Valve Insufficiency; Arterioles; Blood Pressure; Female; Heart Rate; Humans; Hyd | 1981 |
[Long-term treatment with quinapril in chronic aortic and mitral insufficiency].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease; | 1995 |
Afterload reduction in severe aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Feasibility Studies; Female; Hemodynamics; Humans; Hydralazine; M | 2001 |
Precipitation of heart failure following sudden withdrawal of hydralazine.
Topics: Administration, Oral; Aged; Aortic Valve Insufficiency; Digoxin; Furosemide; Heart Failure; Hemodyna | 1979 |
Effects of stopping long-term vasodilator therapy in patients with chronic aortic insufficiency.
Topics: Adult; Aortic Valve Insufficiency; Female; Follow-Up Studies; Humans; Hydralazine; Male; Radionuclid | 1992 |
Beneficial long-term effects of hydralazine in aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Echocardiography; Female; Follow-Up Studies; Humans; Hydralazine; | 1990 |
[Effect of hydralazine on the ventricular function in chronic aortic insufficiency].
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Cardiac Output; Exercise Test; Female; Heart Ventricl | 1987 |
[The effect of dihydralazine on aortic regurgitation].
Topics: Adult; Aortic Valve Insufficiency; Dihydralazine; Female; Hemodynamics; Humans; Hydralazine; Male; M | 1986 |
[Vasodilator agents in chronic asymptomatic aortic insufficiency: echocardiographic study].
Topics: Adult; Aged; Aortic Valve Insufficiency; Captopril; Chronic Disease; Echocardiography; Female; Hemod | 1985 |
When to intervene in chronic aortic regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Echocardiography; Heart Ventricles; Humans; Hydralazine | 1986 |