hydralazine has been researched along with Angiogenesis, Pathologic in 10 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to investigate the effects of sodium valproate (VPA), a histone deacetylase inhibitor, in combination with hydralazine hydrochloride (Hy), a DNA methylation inhibitor, on the expression of VEGI and its related receptors in human osteosarcoma (OS) cell lines and human microvascular endothelial (HMVE) cells." | 7.91 | Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. ( Fujihara, Y; Futani, H; Kobayashi, K; Kumanishi, S; Nakasho, K; Nishiura, H; Yamanegi, K; Yoshiya, S, 2019) |
| " The aim of the present study was to investigate the effects of sodium valproate (VPA), a histone deacetylase inhibitor, in combination with hydralazine hydrochloride (Hy), a DNA methylation inhibitor, on the expression of VEGI and its related receptors in human osteosarcoma (OS) cell lines and human microvascular endothelial (HMVE) cells." | 3.91 | Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. ( Fujihara, Y; Futani, H; Kobayashi, K; Kumanishi, S; Nakasho, K; Nishiura, H; Yamanegi, K; Yoshiya, S, 2019) |
| "Aliskiren reduced the atherosclerotic plaque area and plaque neovessel density." | 1.40 | Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques. ( Cheng, XW; Hamrah, MS; Hao, CN; Hayashi, M; Hu, L; Kuzuya, M; Murohara, T; Shi, GP; Takeshita, K; Wu, H, 2014) |
| " Administration of 5 mg/kg of hydralazine following dosing with the PFOB emulsion reduced the 19F signal intensity from the murine tumors RIF-1 and KHT and from the human tumour HT29 with no or little reduction in the SCCVII/Ha murine and HX118 human tumours." | 1.29 | [Use of fluorine-19 nuclear resonance spectroscopy for the measurement of changes induced in blood perfusion volume in experimental tumors in vivo]. ( Adams, G; Counsell, C; Thomas, C; Wood, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Camaré, C | 1 |
| Vanucci-Bacqué, C | 1 |
| Augé, N | 1 |
| Pucelle, M | 1 |
| Bernis, C | 1 |
| Swiader, A | 1 |
| Baltas, M | 1 |
| Bedos-Belval, F | 1 |
| Salvayre, R | 1 |
| Nègre-Salvayre, A | 1 |
| Kumanishi, S | 1 |
| Yamanegi, K | 1 |
| Nishiura, H | 1 |
| Fujihara, Y | 1 |
| Kobayashi, K | 1 |
| Nakasho, K | 1 |
| Futani, H | 1 |
| Yoshiya, S | 1 |
| Wu, H | 1 |
| Cheng, XW | 1 |
| Hu, L | 1 |
| Hao, CN | 1 |
| Hayashi, M | 1 |
| Takeshita, K | 1 |
| Hamrah, MS | 1 |
| Shi, GP | 1 |
| Kuzuya, M | 1 |
| Murohara, T | 2 |
| Zhang, Q | 1 |
| Lin, Z | 1 |
| Yin, X | 1 |
| Tang, L | 1 |
| Luo, H | 1 |
| Li, H | 1 |
| Zhang, Y | 1 |
| Luo, W | 1 |
| Manley, E | 1 |
| Waxman, DJ | 1 |
| Thomas, C | 2 |
| Counsell, C | 2 |
| Wood, P | 2 |
| Adams, G | 2 |
| Katoh, M | 1 |
| Egashira, K | 1 |
| Mitsui, T | 1 |
| Chishima, S | 1 |
| Takeshita, A | 1 |
| Narita, H | 1 |
| Begg, AC | 1 |
| Hofland, I | 1 |
| Van Der Pavert, I | 1 |
| Van Der Schueren, B | 1 |
| Haustermans, K | 1 |
| Sasaki, K | 1 |
| Ikeda, H | 1 |
| Sugaya, T | 1 |
| Shimada, T | 1 |
| Shintani, S | 1 |
| Imaizumi, T | 1 |
| Sansom, J | 1 |
| Stratford, I | 1 |
10 other studies available for hydralazine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives.
Topics: Aldehydes; Cell Line; Endothelial Cells; Humans; Hydralazine; Neovascularization, Pathologic; Oxidat | 2017 |
Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells.
Topics: Bone Neoplasms; Cell Line; Cell Line, Tumor; Drug Synergism; Endothelial Cells; Enzyme Inhibitors; E | 2019 |
Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques.
Topics: Amides; Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carrier | 2014 |
In vitro and in vivo study of hydralazine, a potential anti-angiogenic agent.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Fibroblast Growth Factor 2; Gen | 2016 |
Impact of tumor blood flow modulation on tumor sensitivity to the bioreductive drug banoxantrone.
Topics: Angiogenesis Inhibitors; Animals; Anthraquinones; Antineoplastic Agents; Axitinib; Cell Hypoxia; Cel | 2013 |
[Use of fluorine-19 nuclear resonance spectroscopy for the measurement of changes induced in blood perfusion volume in experimental tumors in vivo].
Topics: Animals; Blood Volume; Fluorine Radioisotopes; Hydralazine; Magnetic Resonance Spectroscopy; Mice; N | 1993 |
Angiotensin-converting enzyme inhibitor prevents plasminogen activator inhibitor-1 expression in a rat model with cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Coronary Vessels; Enzyme I | 2000 |
Use of thymidine analogues to indicate vascular perfusion in tumours.
Topics: Animals; Blood Flow Velocity; Female; Flow Cytometry; Hydralazine; Idoxuridine; Image Processing, Co | 2000 |
Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis.
Topics: Angiotensin Receptor Antagonists; Animals; Blood Pressure; Capillaries; Chemokine CCL2; Endothelial | 2002 |
The perfluorocarbon emulsion PFOB: potential indicator of change in blood volume using fluorine-19 NMR spectroscopy.
Topics: Animals; Blood Volume; Carcinoma, Squamous Cell; Contrast Media; Fluorocarbons; Hydralazine; Hydroca | 1992 |