hydralazine has been researched along with Adverse Drug Event in 26 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydralazine is a vasodilator used to treat hypertension, pre-eclampsia, and heart failure." | 5.22 | A review on the clinical pharmacokinetics of hydralazine. ( Alqahtani, F; Ashraf, W; Hussain, I; Imran, I; Khalid, S; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Shahzad Qamar, A; Zamir, A, 2022) |
| "Acrolein is a highly toxic aldehyde involved in a number of diseases as well as drug-induced toxicities." | 1.32 | Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity. ( Burcham, PC; Fontaine, FR; Kaminskas, LM; Petersen, DR; Pyke, SM, 2004) |
| "Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases." | 1.27 | [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (57.69) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Shahzad Qamar, A | 1 |
| Zamir, A | 1 |
| Khalid, S | 1 |
| Ashraf, W | 1 |
| Imran, I | 1 |
| Hussain, I | 1 |
| Rehman, AU | 1 |
| Saeed, H | 1 |
| Majeed, A | 1 |
| Alqahtani, F | 1 |
| Rasool, MF | 1 |
| Yee, J | 1 |
| Marzano, AV | 1 |
| Vezzoli, P | 1 |
| Crosti, C | 1 |
| KIRKENDALL, WM | 1 |
| PAGE, EB | 1 |
| EVANS, DA | 1 |
| PALSSON, V | 1 |
| Burcham, PC | 1 |
| Fontaine, FR | 1 |
| Kaminskas, LM | 1 |
| Petersen, DR | 1 |
| Pyke, SM | 1 |
| Laustsen, G | 1 |
| Gilbert, M | 1 |
| Wimett, L | 1 |
| Nonaka, Y | 1 |
| Takei, S | 1 |
| Thiele, KG | 1 |
| Muehrcke, RC | 1 |
| Berning, H | 1 |
| Clark, BG | 1 |
| Vestal, RE | 1 |
| DeSwarte, RD | 1 |
| Wollina, U | 1 |
| Tingle, MD | 1 |
| Park, BK | 1 |
| Amano, K | 1 |
| Takeuchi, T | 1 |
| Daniele, E | 1 |
| De Nardo, D | 1 |
| Schwarz, JA | 1 |
| Cohmen, G | 1 |
| Alarcón-Segovia, D | 1 |
| Kraus, A | 1 |
| Dorfmann, H | 1 |
| Kahn, MF | 1 |
| de Sèze, S | 1 |
| Harpey, JP | 1 |
| Twrdy, E | 1 |
| Tan, EM | 1 |
| Hart, FD | 1 |
8 reviews available for hydralazine and Adverse Drug Event
| Article | Year |
|---|---|
A review on the clinical pharmacokinetics of hydralazine.
Topics: Drug-Related Side Effects and Adverse Reactions; Female; Heart Failure; Humans; Hydralazine; Hyperte | 2022 |
Drug-induced lupus: an update on its dermatologic aspects.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoa | 2009 |
[Drug-induced lupus erythematosus].
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Hu | 2007 |
[Drug-induced lupus erythematosus].
Topics: Autoimmunity; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydr | 2000 |
[Report on the incidence and pathogenetic problems of drug-induced gastroduodenal lesions].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Drug-Related Side Effects and Adverse Reactions; Est | 1978 |
Drug-related lupus syndromes and their relationship to spontaneously occurring systemic lupus erythematosus.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; | 1991 |
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus].
Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and | 1972 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
18 other studies available for hydralazine and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
PGX: Pharmacogenomics During Generation X.
Topics: Anticoagulants; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Heart Failure; H | 2016 |
Polyneuritis occurring during hydralazine therapy; report of two cases and discussion of adverse reactions to hydralazine.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Neuritis | 1958 |
INDIVIDUAL VARIATIONS OF DRUG METABOLISM AS A FACTOR IN DRUG TOXICITY.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Drug-Related Side Effects and Adverse Reactions; Enzyme I | 1965 |
[Apresoline poisoning following prolonged treatment].
Topics: Drug-Related Side Effects and Adverse Reactions; Hydralazine | 1961 |
Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity.
Topics: Acrolein; Animals; Antihypertensive Agents; Cells, Cultured; Cytoprotection; Drug-Related Side Effec | 2004 |
A look back at the most influential drug approvals of 2005.
Topics: Amyloid; Analgesics; Anticonvulsants; Antiparkinson Agents; Diabetes Mellitus, Type 2; Diphtheria-Te | 2006 |
[Kidney diseases caused by drugs].
Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A | 1967 |
Adverse drug reactions in the elderly: case studies.
Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonid | 1984 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus | 1984 |
The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias.
Topics: Animals; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythrocyte Count; Hematologic Di | 1993 |
[Drug-induced disorders of lupus erythematosus type (author's transl)].
Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse | 1977 |
[Drug-induced lupus erythematosus-like syndromes].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adv | 1976 |
[Possible causes of drug induced side effects in elderly people].
Topics: Aged; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Geriatrics; Humans; Hy | 1973 |
Hypersensitivity reactions.
Topics: Autoimmune Diseases; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; | 1974 |
Drug-induced arthritis.
Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contrace | 1974 |