Page last updated: 2024-10-28

hydralazine and Acute Kidney Injury

hydralazine has been researched along with Acute Kidney Injury in 23 studies

Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Hydralazine has shown renoprotective effects in multiple kidney diseases and was shown to be a potent xanthine oxidase (XO) inhibitor."5.91Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease. ( Chang, TT; Chen, C; Chen, JW; Chiang, CH; Fang, SY; Lin, SC, 2023)
"Hydralazine has shown renoprotective effects in multiple kidney diseases and was shown to be a potent xanthine oxidase (XO) inhibitor."1.91Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease. ( Chang, TT; Chen, C; Chen, JW; Chiang, CH; Fang, SY; Lin, SC, 2023)
"We present a case of acute renal failure due to severe preeclampsia successfully treated with the infusion of a low dose of dopamine."1.29Low-dose dopamine in treating acute renal failure caused by preeclampsia. ( Anai, T; Miyakawa, I; Nasu, K; Yoshimatsu, J, 1996)
"Until recently acute renal failure in scleroderma has been uniformly fatal."1.26Medical treatment of hypertension and renal failure in scleroderma. ( Barnett, AJ, 1981)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's1 (4.35)18.2507
2000's2 (8.70)29.6817
2010's2 (8.70)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Leu, JG1
Su, WH1
Chen, YC1
Liang, YJ1
Chiang, CH1
Chen, C1
Fang, SY1
Lin, SC1
Chen, JW1
Chang, TT1
Tampe, B1
Steinle, U1
Tampe, D1
Carstens, JL1
Korsten, P1
Zeisberg, EM1
Müller, GA1
Kalluri, R1
Zeisberg, M1
Ogawa, Y1
Mukoyama, M1
Yokoi, H1
Kasahara, M1
Mori, K1
Kato, Y1
Kuwabara, T1
Imamaki, H1
Kawanishi, T1
Koga, K1
Ishii, A1
Tokudome, T1
Kishimoto, I1
Sugawara, A1
Nakao, K1
LICHTIG-DINULESCU, E1
BOROS, I1
MCQUIGGAN, MC1
OLIVER, WJ1
LITTLER, ER1
CERNY, JC1
Prasad, GV1
Vincent, L1
Hamilton, R1
Lim, K1
Schrier, RW1
Henderson, HS1
Tisher, CC1
Tannen, RL1
Thiele, KG1
Muehrcke, RC1
Berning, H1
Barnett, AJ1
Sinclair, AJ1
Warrington, SJ1
Nasu, K1
Yoshimatsu, J1
Anai, T1
Miyakawa, I1
Hassan, K1
Weissmam, I1
Osman, S1
Gery, R1
Oettinger, M1
Shasha, SM1
Kristal, B1
Moorthy, AV1
Wu, MJ1
Beirne, GJ1
Sundstrom, WS1
Mitnick, PD1
Feig, PU1
Lam, M1
Ricanati, ES1
Khan, MA1
Kushner, I1
Diethelm, AG1
Hartley, MW1
Aldrete, JS1
Sterling, WA1
Morgan, JM1
Fernandes, M1
Kim, KE1
Moyer, JH1
Acchiardo, SR1
Black, WD1
Britt, L1
McKeown, JW1
Johnson, JG1
Hatch, F1
Mattern, WD1
Sommers, SC1
Kassirer, JP1
Sevitt, LH1
Evans, DJ1
Wrong, OM1
Turkington, RW1
Delcher, HK1
Neelon, FA1
Gitelman, HJ1

Reviews

1 review available for hydralazine and Acute Kidney Injury

ArticleYear
Hypertensive emergencies.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume

1974

Other Studies

22 other studies available for hydralazine and Acute Kidney Injury

ArticleYear
Hydralazine attenuates renal inflammation in diabetic rats with ischemia/reperfusion acute kidney injury.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Acute Kidney Injury; Animals; Cells, Cultured; Coculture Techniques; Diabetes Mellitus, Experimental

2021
Xanthine oxidase/NADPH oxidase inhibition by hydralazine attenuates acute kidney injury and prevents the transition of acute kidney injury to chronic kidney disease.
    Life sciences, 2023, Aug-15, Volume: 327

    Topics: Acute Kidney Injury; Animals; Enzyme Inhibitors; Fibrosis; Humans; Hydralazine; Inflammation; Kidney

2023
Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression.
    Kidney international, 2017, Volume: 91, Issue:1

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; CpG Islands; Dioxygenases; D

2017
Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:7

    Topics: Acute Kidney Injury; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured;

2012
[Acute renal insufficiency during hydrazinophthalazine therapy of chronic renal insufficiency].
    Medicina interna, 1957, Volume: 9, Issue:8

    Topics: Acute Kidney Injury; Humans; Hydralazine; Kidney Failure, Chronic; Renal Insufficiency, Chronic

1957
HEMOLYTIC UREMIC SYNDROME.
    JAMA, 1965, Mar-08, Volume: 191

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Child; Diagnosis; Dialysis; Diarrhea; Drug Therapy; Glomerul

1965
Minimal change disease in association with fire coral (Millepora species) exposure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Acute Kidney Injury; Animals; Anthozoa; Barbados; Bites and Stings; Combined Modality Therapy; Divin

2006
Nephropathy associated with heat stress and exercise.
    Annals of internal medicine, 1967, Volume: 67, Issue:2

    Topics: Acute Kidney Injury; Adult; Anuria; Aspartate Aminotransferases; Blood Urea Nitrogen; Heat Exhaustio

1967
[Kidney diseases caused by drugs].
    Deutsche medizinische Wochenschrift (1946), 1967, Sep-08, Volume: 92, Issue:36

    Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A

1967
Medical treatment of hypertension and renal failure in scleroderma.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:4

    Topics: Acute Kidney Injury; Adult; Female; Humans; Hydralazine; Hypertension; Minoxidil; Propranolol; Scler

1981
Severe renal failure in hydralazine-induced lupus.
    Human toxicology, 1981, Volume: 1, Issue:1

    Topics: Acute Kidney Injury; Aged; Female; Humans; Hydralazine; Lupus Vulgaris

1981
Low-dose dopamine in treating acute renal failure caused by preeclampsia.
    Gynecologic and obstetric investigation, 1996, Volume: 42, Issue:2

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Blood Urea Nitrogen; Cesarean Section; Creatini

1996
Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis.
    Nephron, 2001, Volume: 87, Issue:1

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Rena

2001
Control of hypertension with acute renal failure in scleroderma without nephrectomy.
    Lancet (London, England), 1978, Mar-11, Volume: 1, Issue:8063

    Topics: Acute Kidney Injury; Humans; Hydralazine; Hypertension, Malignant; Male; Middle Aged; Propranolol; R

1978
Control of hypertension and reversal of renal failure in scleroderma.
    The New England journal of medicine, 1978, Oct-19, Volume: 299, Issue:16

    Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Humans; Hydralazine; Hypertension, Malignant; M

1978
Reversal of severe renal failure in systemic sclerosis.
    Annals of internal medicine, 1978, Volume: 89, Issue:5 Pt 1

    Topics: Acute Kidney Injury; Biopsy; Female; Humans; Hydralazine; Hypertension, Renal; Kidney; Methyldopa; M

1978
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:2

    Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guan

1975
Results of treatment of hypertension.
    Lancet (London, England), 1971, Jan-30, Volume: 1, Issue:7692

    Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Hum

1971
Experience with hemodialysis and renal transplantation in patients with malignant hypertension.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Acute Kidney Injury; Adult; Brain Diseases; Diazoxide; Diet Therapy; Female; Follow-Up Studies; Furo

1974
Oliguric acute renal failure in malignant hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:2

    Topics: Acute Kidney Injury; Adult; Anuria; Blood Urea Nitrogen; Diagnosis, Differential; Female; Glomerulon

1972
Acute oliguric renal failure due to accelerated (malignant) hypertension.
    The Quarterly journal of medicine, 1971, Volume: 40, Issue:157

    Topics: Acute Kidney Injury; Adolescent; Adult; Antihypertensive Agents; Anuria; Blood Urea Nitrogen; Diazox

1971
Hypercalcemia following acute renal failure.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:8

    Topics: Acute Kidney Injury; Alkaline Phosphatase; Ampicillin; Blood Urea Nitrogen; Calcium; Convalescence;

1968