hydralazine has been researched along with Acute Disease in 33 studies
Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent.
hydralazine : The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 9.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "Patients with acute heart failure (HF) in Africa are rarely being treated with a hydralazine/nitrates combination." | 9.22 | Bi treatment with hydralazine/nitrates vs. placebo in Africans admitted with acute HEart Failure (BA-HEF). ( Ba, SA; Cotter, G; Damasceno, A; Davison, BA; Dzudie, A; Edwards, C; Kouam, CK; Mayosi, BM; Milo, O; Mondo, C; Ogah, O; Ogola, E; Ojji, D; Sani, MU; Sliwa, K; Yonga, G, 2016) |
| "We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol." | 9.15 | Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011) |
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 8.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| "The aim of this study was to evaluate the use of as-needed (PRN) labetalol and hydralazine [intravenous (IV) or oral] in hospitalized medicine patients for the treatment of severe asymptomatic hypertension and to examine the potential negative outcomes associated with their use." | 7.88 | Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients. ( Gaynor, MF; Vondracek, S; Wright, GC, 2018) |
| " To investigate the effects of a new ARB, olmesartan, on immune-mediated myocardial injury, the protective effects of olmesartan on the development of murine acute myocarditis caused by CVB3 (coxsackievirus B3) were analysed." | 7.73 | Effect of the angiotensin II receptor blocker olmesartan on the development of murine acute myocarditis caused by coxsackievirus B3. ( Seko, Y, 2006) |
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 5.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "Patients with acute heart failure (HF) in Africa are rarely being treated with a hydralazine/nitrates combination." | 5.22 | Bi treatment with hydralazine/nitrates vs. placebo in Africans admitted with acute HEart Failure (BA-HEF). ( Ba, SA; Cotter, G; Damasceno, A; Davison, BA; Dzudie, A; Edwards, C; Kouam, CK; Mayosi, BM; Milo, O; Mondo, C; Ogah, O; Ogola, E; Ojji, D; Sani, MU; Sliwa, K; Yonga, G, 2016) |
| "We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol." | 5.15 | Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial. ( Baggio, MR; Berezowski, AT; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Martins, WP, 2011) |
| "This is the second case report of hydralazine induced Sweet's syndrome and lupus erythematosus." | 4.78 | Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature. ( Franz, T; Medsger, TA; Ramsey-Goldman, R; Solano, FX, 1990) |
| "The aim of this study was to evaluate the use of as-needed (PRN) labetalol and hydralazine [intravenous (IV) or oral] in hospitalized medicine patients for the treatment of severe asymptomatic hypertension and to examine the potential negative outcomes associated with their use." | 3.88 | Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients. ( Gaynor, MF; Vondracek, S; Wright, GC, 2018) |
| " To investigate the effects of a new ARB, olmesartan, on immune-mediated myocardial injury, the protective effects of olmesartan on the development of murine acute myocarditis caused by CVB3 (coxsackievirus B3) were analysed." | 3.73 | Effect of the angiotensin II receptor blocker olmesartan on the development of murine acute myocarditis caused by coxsackievirus B3. ( Seko, Y, 2006) |
| "Hydralazine was stopped and the patient gradually became asymptomatic." | 1.29 | Effect of acute cytomegalovirus infection on drug-induced SLE. ( Geltner, D; Schattner, A; Sthoeger, Z, 1994) |
| "Hypertension is a frequent complication of a scorpion's sting in children, and specific antihypertensive therapy is indicated in severe cases." | 1.28 | Vasodilators and hypertensive encephalopathy following scorpion envenomation in children. ( Gueron, M; Sofer, S, 1990) |
| "Thus, in this canine model of acute pulmonary embolism: 1) VA/Q distributions were moderately impaired accounting for only slight hypoxemia, and 2) pulmonary hypertension was partially reversible by hydralazine and by nitroprusside without associated non-flow-dependent change in VA/Q distributions and arterial oxygenation." | 1.28 | Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension. ( Delcroix, M; Leeman, M; Lejeune, P; Mélot, C; Naeije, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (60.61) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 5 (15.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, C | 1 |
| Soni, A | 1 |
| Gupta, A | 1 |
| Verma, A | 1 |
| Verma, S | 1 |
| Gaynor, MF | 1 |
| Wright, GC | 1 |
| Vondracek, S | 1 |
| Sliwa, K | 1 |
| Damasceno, A | 1 |
| Davison, BA | 1 |
| Mayosi, BM | 1 |
| Sani, MU | 1 |
| Ogah, O | 1 |
| Mondo, C | 1 |
| Ojji, D | 1 |
| Dzudie, A | 1 |
| Kouam, CK | 1 |
| Yonga, G | 1 |
| Ba, SA | 1 |
| Ogola, E | 1 |
| Edwards, C | 1 |
| Milo, O | 1 |
| Cotter, G | 1 |
| Schrock, JW | 1 |
| Emerman, CL | 1 |
| Baggio, MR | 1 |
| Martins, WP | 1 |
| Calderon, AC | 1 |
| Berezowski, AT | 1 |
| Marcolin, AC | 1 |
| Duarte, G | 1 |
| Cavalli, RC | 1 |
| Odunukan, OW | 1 |
| Abudiab, MM | 1 |
| Sinak, LJ | 1 |
| FARIDAY, EE | 1 |
| DAVID, JK | 1 |
| Seko, Y | 1 |
| Gascho, JA | 1 |
| Martins, JB | 1 |
| Marcus, ML | 1 |
| Kerber, RE | 1 |
| Mason, DT | 2 |
| Awan, NA | 2 |
| Joye, JA | 1 |
| Lee, G | 1 |
| DeMaria, AN | 1 |
| Amsterdam, EA | 1 |
| Myers, JL | 1 |
| Augur, NA | 1 |
| Hod, M | 1 |
| Friedman, S | 1 |
| Theodor, E | 1 |
| Ovadia, J | 1 |
| Massie, BM | 1 |
| Kramer, B | 1 |
| Haughom, F | 1 |
| László, B | 1 |
| Kendrey, G | 1 |
| Clark, AJ | 1 |
| McMichael, HB | 1 |
| Schattner, A | 1 |
| Sthoeger, Z | 1 |
| Geltner, D | 1 |
| Gavaghan, BJ | 1 |
| Lapointe, JM | 1 |
| Thomas, WP | 1 |
| Abakumov, GZ | 1 |
| Lukienko, PI | 1 |
| Miller, RR | 1 |
| Bartoli, E | 1 |
| Massarelli, G | 1 |
| Solinas, A | 1 |
| Faedda, R | 1 |
| Chiandussi, L | 1 |
| Fleischmann, LE | 1 |
| Yamori, Y | 1 |
| Hamashima, Y | 1 |
| Horie, R | 1 |
| Handa, H | 1 |
| Sato, M | 1 |
| Ramsey-Goldman, R | 1 |
| Franz, T | 1 |
| Solano, FX | 1 |
| Medsger, TA | 1 |
| Sofer, S | 1 |
| Gueron, M | 1 |
| Delcroix, M | 1 |
| Mélot, C | 1 |
| Lejeune, P | 1 |
| Leeman, M | 1 |
| Naeije, R | 1 |
| Roschlau, G | 1 |
| Baumgarten, R | 1 |
| Fengler, JD | 1 |
| Reti, LL | 1 |
| Ross, A | 1 |
| Kloss, M | 1 |
| Paull, J | 1 |
| Markman, L | 1 |
| Spinnato, JA | 1 |
| Sibai, BM | 1 |
| Anderson, GD | 1 |
| Ghignone, M | 1 |
| Girling, L | 1 |
| Prewitt, RM | 1 |
| Hart, FD | 1 |
| Belman, AB | 1 |
| Lewy, PR | 1 |
| López, J | 1 |
| Vargas, R | 1 |
| Le Lorie, J | 1 |
| Pardo, EG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Placebo-controlled, Double-blind, Randomized Study to Compare Hydralazine-isosorbide-dinitrate(HYIS) Versus Placebo on Top of Std Care in African Patients With Acute Heart Failure (AHF) and Left Ventricular Dysfunction[NCT01822808] | Phase 3 | 500 participants (Anticipated) | Interventional | 2013-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydralazine and Acute Disease
| Article | Year |
|---|---|
Observation unit management of acute decompensated heart failure.
Topics: Acute Disease; Adrenergic beta-Antagonists; Antihypertensive Agents; Centers for Medicare and Medica | 2009 |
Afterload reduction in the management of congestive heart failure following acute myocardial infarction.
Topics: Acute Disease; Dopamine; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocardial Infarction; Ni | 1978 |
Hydralazine induced lupus and Sweet's syndrome. Report and review of the literature.
Topics: Acute Disease; Adult; Fever; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Neutrophils; | 1990 |
3 trials available for hydralazine and Acute Disease
| Article | Year |
|---|---|
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd | 2017 |
Bi treatment with hydralazine/nitrates vs. placebo in Africans admitted with acute HEart Failure (BA-HEF).
Topics: Acute Disease; Adult; Africa South of the Sahara; Aged; Black People; Double-Blind Method; Heart Fai | 2016 |
Changes in fetal and maternal Doppler parameters observed during acute severe hypertension treatment with hydralazine or labetalol: a randomized controlled trial.
Topics: Acute Disease; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; | 2011 |
27 other studies available for hydralazine and Acute Disease
| Article | Year |
|---|---|
Retrospective review of the use of as-needed hydralazine and labetalol for the treatment of acute hypertension in hospitalized medicine patients.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Adrenergic Antagonists; Adult; Age | 2018 |
48-year-old man with cough and leg swelling.
Topics: Acute Disease; Antihypertensive Agents; Cerebrovascular Circulation; Cough; Dyspnea; Echocardiograph | 2012 |
ACUTE GLOMERULONEPHRITIS IN CHILDREN. A REVIEW OF THIRTY-EIGHT CASES.
Topics: Acute Disease; Child; Drug Therapy; Glomerulonephritis; Hydralazine; Infant; Reserpine; Urine | 1964 |
Effect of the angiotensin II receptor blocker olmesartan on the development of murine acute myocarditis caused by coxsackievirus B3.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Blood | 2006 |
Effects of volume expansion and vasodilators in acute pericardial tamponade.
Topics: Acute Disease; Animals; Cardiac Output; Cardiac Tamponade; Dextrans; Dogs; Hemodynamics; Hydralazine | 1981 |
Treatment of acute and chronic congestive heart failure by vasodilator-afterload reduction.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Cardiac Output; Chronic Disease; Diastole; H | 1980 |
Hydralazine-induced cholangitis.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cholangitis; Cholecystitis; Female; Humans; H | 1984 |
[Acute liver disease during treatment of severe preeclampsia].
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Liver Dis | 1983 |
Acute and long-term effects of vasodilator therapy on resting and exercise hemodynamics and exercise tolerance.
Topics: Acute Disease; Adult; Aged; Blood Pressure; Exercise Test; Heart Failure; Heart Rate; Hemodynamics; | 1981 |
[Acute liver damage in patients treated with a depressant (dihydralazine sulfate)].
Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Dihydralazine; Female; Humans; Hydralaz | 1981 |
Hydrallazine alone in acute left ventricular failure.
Topics: Acute Disease; Heart Failure; Humans; Hydralazine; Male; Middle Aged; Oxygen Inhalation Therapy | 1981 |
Effect of acute cytomegalovirus infection on drug-induced SLE.
Topics: Acute Disease; Autoimmune Diseases; Cytomegalovirus Infections; Disease Susceptibility; Female; Huma | 1994 |
Acute onset of pulmonary necrotising arteritis in a dog with a left-to-right patent ductus arteriosus.
Topics: Acute Disease; Animals; Antihypertensive Agents; Dog Diseases; Dogs; Ductus Arteriosus, Patent; Echo | 1998 |
[Effect of apressin, obsidan, diprazine and their combination on the concentration of NAD and NADH2 in the liver and brain of hypoxic rats].
Topics: Acute Disease; Animals; Brain Chemistry; Drug Combinations; Female; Hydralazine; Hypoxia; Liver; NAD | 1978 |
Acute hepatitis with bridging necrosis due to hydralazine intake. Report of a case.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Hydralazine; Liver; Middle Ag | 1979 |
Management of hypertensive crisis in children.
Topics: Acute Disease; Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Diazoxide; Humans; Hy | 1977 |
Pathogenesis of acute arterial fat deposition in spontaneously hypertensive rats.
Topics: Acute Disease; Animals; Arteries; Capillary Permeability; Cerebral Arteries; Cholesterol, Dietary; H | 1975 |
Vasodilators and hypertensive encephalopathy following scorpion envenomation in children.
Topics: Acute Disease; Animals; Brain Diseases; Child; Child, Preschool; Humans; Hydralazine; Hypertension; | 1990 |
Effects of vasodilators on gas exchange in acute canine embolic pulmonary hypertension.
Topics: Acute Disease; Alprostadil; Animals; Dogs; Hydralazine; Hypertension, Pulmonary; Nitroprusside; Pulm | 1990 |
[Dihydralazine hepatitis. Morphologic and clinical criteria for diagnosis].
Topics: Acute Disease; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Different | 1990 |
The management of severe preeclampsia with intravenous magnesium sulphate, hydralazine and central venous catheterization.
Topics: Acute Disease; Catheterization, Central Venous; Drug Therapy, Combination; Female; Humans; Hydralazi | 1987 |
Fetal distress after hydralazine therapy for severe pregnancy-induced hypertension.
Topics: Acute Disease; Cesarean Section; Eclampsia; Female; Fetal Distress; Gestational Age; Humans; Hydrala | 1986 |
Effects of vasodilators on canine cardiopulmonary function when a decrease in cardiac output complicates an increase in right ventricular afterload.
Topics: Acute Disease; Animals; Cardiac Output; Diastole; Dogs; Ferricyanides; Heart Ventricles; Hydralazine | 1985 |
Drug-induced arthritis.
Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contrace | 1974 |
Acute transient renin-mediated hypertension in children following urinary diversion.
Topics: Acute Disease; Adolescent; Blood Volume; Child; Creatinine; Dermatologic Surgical Procedures; Female | 1974 |
Emergency reduction of blood pressure.
Topics: Acute Disease; Antihypertensive Agents; Diazoxide; Ferricyanides; Humans; Hydralazine; Injections, I | 1971 |
[Recent progress in the knowledge of arterial hypertension. VII. Acute effects of antihypertensive drugs on kidney function].
Topics: Acute Disease; Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertensi | 1967 |