hycanthone has been researched along with Pregnancy in 7 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gross chromosomal aberrations were assessed in human leucocyte cultures and in bone marrow preparations from drug-treated mice." | 1.25 | A comparative study on the genetic effects of hycanthone and oxamniquine. ( Ellis, JH; Holden, HE; Hyneck, ML; Ray, VA, 1975) |
| "Hycanthone has been tested for embryotoxic activity in mice and rabbits." | 1.25 | Evaluation of the teratogenic activity of hycanthone in mice and rabbits. ( Adamson, RH; Sieber, SM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bishun, N | 1 |
| Smith, N | 1 |
| Williams, D | 1 |
| Ray, VA | 1 |
| Holden, HE | 1 |
| Ellis, JH | 1 |
| Hyneck, ML | 1 |
| Green, S | 1 |
| Springer, JA | 1 |
| Russell, WL | 1 |
| Sieber, SM | 1 |
| Adamson, RH | 1 |
| Farah, A | 1 |
| Berberian, DA | 1 |
| Davison, C | 1 |
| Dennis, EW | 1 |
| Donikian, MA | 1 |
| Drobeck, HP | 1 |
| Ferrari, RA | 1 |
| Yarinsky, A | 1 |
7 other studies available for hycanthone and Pregnancy
| Article | Year |
|---|---|
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
Mutations, chromosome aberrations and cancer.
Topics: Animals; Carcinogens, Environmental; Chemical Industry; Chromosome Aberrations; Cocarcinogenesis; Co | 1978 |
A comparative study on the genetic effects of hycanthone and oxamniquine.
Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; | 1975 |
Additional statistical evaluation and pharmacological considerations of hycanthone methanesulfonate-induced dominant lethality.
Topics: Analysis of Variance; Animals; Corpus Luteum; Embryo Implantation; Female; Genes, Dominant; Genes, L | 1975 |
Results of tests for possible transmitted genetic effects of hycanthone in mammals.
Topics: Animals; Female; Genes; Hycanthone; Male; Mice; Mutagens; Mutation; Pregnancy; Salmonella; Sex Chrom | 1975 |
Evaluation of the teratogenic activity of hycanthone in mice and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Embryo Implantation; Embryo, Mammalian; Female; Fetal Death; G | 1975 |
Hycanthone: a review of its experimental chemotherapy, pharmacology and toxicology.
Topics: Animals; Cats; Cricetinae; Dogs; Drug Tolerance; Female; Haplorhini; Humans; Hycanthone; Male; Mice; | 1974 |