Page last updated: 2024-10-28

hycanthone and Nephrotic Syndrome

hycanthone has been researched along with Nephrotic Syndrome in 1 studies

Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Nephrotic syndrome was the most frequent clinical presentation in both groups."1.28Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy. ( Brito, E; Martinelli, R; Noblat, AC; Rocha, H, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martinelli, R1
Noblat, AC1
Brito, E1
Rocha, H1

Other Studies

1 other study available for hycanthone and Nephrotic Syndrome

ArticleYear
Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy.
    Kidney international, 1989, Volume: 35, Issue:5

    Topics: Adult; Antihypertensive Agents; Cyclophosphamide; Diet, Sodium-Restricted; Diuretics; Female; Follow

1989