Page last updated: 2024-10-28

hycanthone and Necrosis

hycanthone has been researched along with Necrosis in 6 studies

Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mengistu, M1
Gigase, PL1
Mortelmans, J1
Van Marck, EA1
Buchanan, N2
Thatcher, CJ1
Cane, RD1
Bartolomeo, B1
Dennis, EW1
Hatchuel, W1

Other Studies

6 other studies available for hycanthone and Necrosis

ArticleYear
Fatal liver toxicity due to hycanthone (Etrenol) in a patient with pre-existing liver disease: a case report.
    Ethiopian medical journal, 1982, Volume: 20, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Hycanthone; Liver Diseases, Parasitic

1982
[Fatal hepatic necrosis after administration of hycanthone].
    Annales de la Societe belge de medecine tropicale, 1979, Volume: 59, Issue:4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Liver; Male; Necrosis; Schistosom

1979
Hycanthone--a danger associated with its use.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-12, Volume: 52, Issue:21

    Topics: Chemical and Drug Induced Liver Injury; Child; Humans; Hycanthone; Necrosis; Thioxanthenes

1977
Fatal hepatic necrosis in association with the use of hycanthone. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Feb-18, Volume: 53, Issue:7

    Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Child; Humans; Hycanthone; Necrosis; Thioxant

1978
Fatal hepatic necrosis in association with the use of hycanthone.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Jul-22, Volume: 54, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Hycanthone; Mortality; Necrosis; Schistosomiasis; Thioxanthe

1978
Fatal hepatic necrosis in association with hycanthone.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Nov-11, Volume: 54, Issue:20

    Topics: Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Necrosis; Nitroquinolines; Oxamniquine;

1978