hycanthone has been researched along with Necrosis in 6 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mengistu, M | 1 |
| Gigase, PL | 1 |
| Mortelmans, J | 1 |
| Van Marck, EA | 1 |
| Buchanan, N | 2 |
| Thatcher, CJ | 1 |
| Cane, RD | 1 |
| Bartolomeo, B | 1 |
| Dennis, EW | 1 |
| Hatchuel, W | 1 |
6 other studies available for hycanthone and Necrosis
| Article | Year |
|---|---|
Fatal liver toxicity due to hycanthone (Etrenol) in a patient with pre-existing liver disease: a case report.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Hycanthone; Liver Diseases, Parasitic | 1982 |
[Fatal hepatic necrosis after administration of hycanthone].
Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Liver; Male; Necrosis; Schistosom | 1979 |
Hycanthone--a danger associated with its use.
Topics: Chemical and Drug Induced Liver Injury; Child; Humans; Hycanthone; Necrosis; Thioxanthenes | 1977 |
Fatal hepatic necrosis in association with the use of hycanthone. A case report.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Child; Humans; Hycanthone; Necrosis; Thioxant | 1978 |
Fatal hepatic necrosis in association with the use of hycanthone.
Topics: Chemical and Drug Induced Liver Injury; Hycanthone; Mortality; Necrosis; Schistosomiasis; Thioxanthe | 1978 |
Fatal hepatic necrosis in association with hycanthone.
Topics: Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Necrosis; Nitroquinolines; Oxamniquine; | 1978 |