Page last updated: 2024-10-28

hycanthone and Lung Neoplasms

hycanthone has been researched along with Lung Neoplasms in 2 studies

Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Hycanthone was administered to Schistosoma mansoni-infected and non-infected Syrian golden hamsters and Swiss mice by intraperitoneal and intramuscular injection of amounts up to the maximum tolerated dose."1.26Carcinogenic potential of hycanthone in mice and hamsters. ( Bulay, O; Clayson, DB; Patil, K; Shubik, P; Urman, H, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, BM1
Watling, DC1
Bulay, O1
Urman, H1
Patil, K1
Clayson, DB1
Shubik, P1

Other Studies

2 other studies available for hycanthone and Lung Neoplasms

ArticleYear
Radiosensitization of pulmonary metastases-I. In vivo testing of hycanthone, insulin and razoxane.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:6

    Topics: Animals; Hycanthone; Insulin; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimenta

1979
Carcinogenic potential of hycanthone in mice and hamsters.
    International journal of cancer, 1979, Jan-15, Volume: 23, Issue:1

    Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Cricetinae; Female; Hycanthone; Hyperplasia; In

1979