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hycanthone and Leukemia P388

hycanthone has been researched along with Leukemia P388 in 3 studies

Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.

Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Archer, S2
Pica-Mattoccia, L1
Cioli, D1
Seyed-Mozaffari, A1
Zayed, AH2
Rej, R1
Rugino, TA1
Perni, RB1
Wentland, MP1
Huang, JI1
Powles, RG1
Aldous, S1
Klingbeil, KM1
Peverly, AD1
Robinson, RG1
Corbett, TH1
Jones, JL1
Mattes, KC1
Rake, JB1
Coughlin, SA1

Other Studies

3 other studies available for hycanthone and Leukemia P388

ArticleYear
Preparation and antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Antineoplastic Agents; Hycanthone; Indicators and Reagents; Leukemia P388; Leukemia, Experi

1988
Analogues of hycanthone and lucanthone as antitumor agents.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:9

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Hycanthone; Leukemia P388; Lucanthone

1983
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Journal of medicinal chemistry, 1998, Sep-10, Volume: 41, Issue:19

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enz

1998