hycanthone has been researched along with Leukemia P388 in 3 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Archer, S | 2 |
| Pica-Mattoccia, L | 1 |
| Cioli, D | 1 |
| Seyed-Mozaffari, A | 1 |
| Zayed, AH | 2 |
| Rej, R | 1 |
| Rugino, TA | 1 |
| Perni, RB | 1 |
| Wentland, MP | 1 |
| Huang, JI | 1 |
| Powles, RG | 1 |
| Aldous, S | 1 |
| Klingbeil, KM | 1 |
| Peverly, AD | 1 |
| Robinson, RG | 1 |
| Corbett, TH | 1 |
| Jones, JL | 1 |
| Mattes, KC | 1 |
| Rake, JB | 1 |
| Coughlin, SA | 1 |
3 other studies available for hycanthone and Leukemia P388
| Article | Year |
|---|---|
Preparation and antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone.
Topics: Animals; Antineoplastic Agents; Hycanthone; Indicators and Reagents; Leukemia P388; Leukemia, Experi | 1988 |
Analogues of hycanthone and lucanthone as antitumor agents.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Hycanthone; Leukemia P388; Lucanthone | 1983 |
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enz | 1998 |