hycanthone has been researched along with Hyperplasia in 1 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hycanthone was administered to Schistosoma mansoni-infected and non-infected Syrian golden hamsters and Swiss mice by intraperitoneal and intramuscular injection of amounts up to the maximum tolerated dose." | 1.26 | Carcinogenic potential of hycanthone in mice and hamsters. ( Bulay, O; Clayson, DB; Patil, K; Shubik, P; Urman, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulay, O | 1 |
| Urman, H | 1 |
| Patil, K | 1 |
| Clayson, DB | 1 |
| Shubik, P | 1 |
1 other study available for hycanthone and Hyperplasia
| Article | Year |
|---|---|
Carcinogenic potential of hycanthone in mice and hamsters.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Cricetinae; Female; Hycanthone; Hyperplasia; In | 1979 |