hycanthone has been researched along with Granuloma in 4 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Almeida, MA | 1 |
| Andrade, ZA | 2 |
| Azevedo de Brito, P | 1 |
| Reid, WA | 1 |
| Loizeaux, PS | 1 |
| Reardon, MJ | 1 |
| Schiltz, JR | 1 |
| Olds, GR | 1 |
| Kresina, TF | 1 |
| Mahmoud, AA | 1 |
4 other studies available for hycanthone and Granuloma
| Article | Year |
|---|---|
Effect of chemotherapy on experimental pulmonary schistosomiasis.
Topics: Animals; Granuloma; Hycanthone; Liver; Lung; Lung Diseases, Parasitic; Male; Mice; Nitroquinolines; | 1983 |
Curative chemotherapy and resistance to reinfection in murine schistosomiasis.
Topics: Animals; Eosinophils; Female; Granuloma; Hycanthone; Inflammation; Liver; Macrophages; Male; Mice; N | 1982 |
The activity of a benzothiopyranoindazole (IA-4 N-oxide) against Schistosoma mansoni infection in rhesus monkeys.
Topics: Animals; Colon; Granuloma; Haplorhini; Hycanthone; Indazoles; Liver; Macaca mulatta; Parasite Egg Co | 1977 |
Effect of chemotherapy on hepatic collagen and glycosaminoglycan metabolism in Schistosoma mansoni-infected mice.
Topics: Animals; Collagen; Dose-Response Relationship, Drug; Glycosaminoglycans; Granuloma; Hycanthone; Live | 1988 |