hycanthone has been researched along with Glomerulonephritis, Membranoproliferative in 1 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Glomerulonephritis, Membranoproliferative: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nephrotic syndrome was the most frequent clinical presentation in both groups." | 1.28 | Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy. ( Brito, E; Martinelli, R; Noblat, AC; Rocha, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martinelli, R | 1 |
| Noblat, AC | 1 |
| Brito, E | 1 |
| Rocha, H | 1 |
1 other study available for hycanthone and Glomerulonephritis, Membranoproliferative
| Article | Year |
|---|---|
Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy.
Topics: Adult; Antihypertensive Agents; Cyclophosphamide; Diet, Sodium-Restricted; Diuretics; Female; Follow | 1989 |