hycanthone has been researched along with Experimental Hepatoma in 2 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hycanthone was administered to Schistosoma mansoni-infected and non-infected Syrian golden hamsters and Swiss mice by intraperitoneal and intramuscular injection of amounts up to the maximum tolerated dose." | 1.26 | Carcinogenic potential of hycanthone in mice and hamsters. ( Bulay, O; Clayson, DB; Patil, K; Shubik, P; Urman, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuda, H | 1 |
| Sarma, DS | 1 |
| Rajalakshmi, S | 1 |
| Zubroff, J | 1 |
| Farber, E | 1 |
| Batzinger, RP | 1 |
| Cha, YN | 1 |
| Bueding, E | 1 |
| Bulay, O | 1 |
| Urman, H | 1 |
| Patil, K | 1 |
| Clayson, DB | 1 |
| Shubik, P | 1 |
2 other studies available for hycanthone and Experimental Hepatoma
| Article | Year |
|---|---|
Induction of hepatic neoplastic lesions in mice with a single dose of hycanthone methanesulfonate after partial hepatectomy.
Topics: Animals; Hepatectomy; Hycanthone; Liver Neoplasms; Liver Neoplasms, Experimental; Liver Regeneration | 1979 |
Carcinogenic potential of hycanthone in mice and hamsters.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Cricetinae; Female; Hycanthone; Hyperplasia; In | 1979 |