hycanthone has been researched along with Astrocytoma, Grade IV in 1 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naidu, MD | 1 |
| Agarwal, R | 1 |
| Pena, LA | 1 |
| Cunha, L | 1 |
| Mezei, M | 1 |
| Shen, M | 1 |
| Wilson, DM | 1 |
| Liu, Y | 1 |
| Sanchez, Z | 1 |
| Chaudhary, P | 1 |
| Wilson, SH | 1 |
| Waring, MJ | 1 |
1 other study available for hycanthone and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.
Topics: Cell Line, Tumor; Circular Dichroism; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glioblastoma; | 2011 |