Page last updated: 2024-08-22

hyaluronoglucosaminidase and Invasiveness, Neoplasm

hyaluronoglucosaminidase has been researched along with Invasiveness, Neoplasm in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.77)	18.7374
1990's	6 (11.32)	18.2507
2000's	16 (30.19)	29.6817
2010's	21 (39.62)	24.3611
2020's	8 (15.09)	2.80

Authors

Authors	Studies
Chen, Y; Jiang, WJ; Jiang, Y; Tian, Y; Wang, JF; Xia, BR; Zhou, H	1
Chennathukuzhi, VM; Cloud, AS; Ganeshkumar, S; Gunewardena, S; Jensen, RA; Kumaraswamy, E; Shimak, RM; Vargheese, AM	1
Hashimoto, Y; Hatakeyama, S; Ohyama, C; Suzuki, T; Tobisawa, Y; Yamamoto, H; Yoneyama, MS; Yoneyama, T	1
Cheng, X; Jiao, X; Wang, X; Ye, J; Yin, X; Zhang, G	1
Aoyama, T; Cho, H; Fujikawa, H; Hara, K; Hashimoto, I; Hiroshima, Y; Ito, H; Kano, K; Kimura, Y; Maezawa, Y; Masuda, M; Miyagi, Y; Morinaga, S; Ogata, T; Oneyama, M; Oshima, T; Oue, N; Rino, Y; Sakamoto, N; Shiozawa, M; Tamagawa, H; Yamada, T; Yamamoto, N; Yasui, W; Yoshikawa, T; Yukawa, N	1
Azih, I; Baskar, R; Dhir, N; Escudero, DO; Ghosh, S; Hasanali, SL; Hennig, MJP; Hoye, K; Hupe, MC; Jordan, AR; Kavuri, S; Klaassen, Z; Knapp, J; Lokeshwar, BL; Lokeshwar, SD; Lokeshwar, VB; Lopez, LE; Manoharan, M; Morera, DS; Racine, RR; Wang, J; Yates, TJ	1
Huang, G; Li, L; Liang, K; Luo, M; Mao, N; Mo, X; Pan, Y; Song, J; Teng, C; Wei, T; Yang, J	1
Chen, Y; Li, L; Zhang, J	1
Dou, D; Du, G; Fan, H; Jiang, Z; Jin, B; Ma, Y; Song, J; Wang, W; Xin, D; Yu, X; Zeng, Y; Zhai, X; Zhang, H; Zhang, X	1
Cox, TR	1
Feng, M; Feng, X; Feng, Y; Hu, Y; Ji, J; Ji, K; Jia, S; Jiang, W; Li, W; Li, Z; Ma, R; Qu, T; Wang, X; Yang, Y	1
Chen, B; Chen, Y; Hao, K; Jiang, L; Jiang, S; Miao, X; Wang, X; Wang, Z; Zhang, W	1
Huang, S; Jin, M; Lin, Z; Ma, H; Shen, Q; Wu, G; Zhang, D; Zhang, T; Zhao, L; Zhou, P	1
Ding, Y; Huang, J; Li, J; Nazar, M; Shen, Q; Tang, Z; Wang, Y; Zhang, C; Zhou, X	1
Du, Y; Gao, F; He, Y; Jin, Z; Liu, Y; Yang, C; Zhang, G	1
Gao, C; Lin, YS; Lu, J; Qi, F; Wang, XD	1
Fiorino, A; Haider, R; Jiricny, J; Marra, G; Menigatti, M; Okoniewski, MJ; Roschitzki, B; Schneider, M; Tiwari, A; Uzozie, A	1
Ding, SJ; Dong, J; Fu, K; Geng, L; Hassan, H; Hou, J; Huang, X; Jami, MS; Li, Y; Liu, M; Peng, H; Singh, RK; Varney, ML; Wang, J; Yu, F	1
Cao, M; Du, Y; Gao, F; He, Y; Liu, Y; Wang, W; Wu, M; Yang, C	1
Hu, Z; Huang, J; Liu, Y; Wang, D; Wang, X; Xu, J; Zhu, H	1
Huang, S; Jin, M; Lv, Q; Ma, H; Nie, X; Shen, Q; Wu, G; Zhang, D; Zhang, T; Zhao, L; Zheng, X; Zhou, P	1
Colombo, R	1
Duncan, RC; Garcia, A; Golshani, R; Hennenlotter, J; Jorda, M; Knapp, J; Kramer, MW; Kuczyk, MA; Lokeshwar, VB; Merseburger, AS; Soloway, MS; Stenzl, A	1
Delpech, B; Ren, GS; Tan, JX; Vasse, M; Wang, XY	1
Li, HY; Ran, L; Ren, GS; Su, XL; Tan, JX; Wang, L; Wang, XY; Zheng, K	1
Deivanayagam, C; Kumar, S; Lee, JH; Moore, LD; Ponnazhagan, S; Pritchard, DG	1
Bakkar, A; Benitez, A; Cerwinka, WH; Lokeshwar, VB; Lopez, LE; Yates, TJ	1
Li, HY; Ren, GS; Shi, Y; Su, XL; Tan, JX; Wang, L; Wang, XY	1
Álvarez, É; Blanco, G; Cordo Russo, RI; Ernst, G; Garcia, MG; Hajos, S; Lompardía, S	1
Farach-Carson, MC; Gurski, LA; Jia, X; Labrada, LN; Nguyen, NT; van Golen, KL; Xiao, L; Xu, X	1
Casey, RC; Grindle, SM; Oegema, TR; Pambuccian, SE; Skubitz, AP; Skubitz, KM	1
Heldin, P	1
Bourguignon, LY; Diedrich, F; Gilad, E; Singleton, PA; Stern, R	1
Toole, BP	1
Chauzy, C; David, L; Delpech, B; Dulong, V; Lamacz, M; Le Cerf, D; Norris, V; Vannier, JP	1
Cui, YH; Dong, W; Sun, H; Wu, T; Xu, HM	1
Cerwinka, WH; Lokeshwar, BL; Lokeshwar, VB	1
Brown, TJ; Brownlee, GR; Nilsson, SK; Udabage, L	1
Aboughalia, AH	1
Chang, NS; Hsu, LJ; Lai, FJ; Lin, YS; Sheu, HM	1
Brown, TJ; Heldin, P; Li, L; Li, Y	1
Bharadwaj, AG; Rector, K; Simpson, MA	1
Gosslar, U; Holzmann, B; Naor, D; Okon, E; Zahalka, MA	1
Diaconu, E; Guo, K; Haqqi, T; Liu, D; Markowitz, S; Mori, H; Pearlman, E; Sy, MS; Willson, J	1
Block, NL; Lokeshwar, VB; Soloway, MS	1
Csóka, AB; Csóka, TB; Frost, GI; Stern, R	1
Kaye, AH; Lepperdinger, G; Novak, U; Stylli, SS	1
Hawley, RG; Kodaka, M; Okada, T; Okuno, H	1
Ba, Y; Hamada, Ji; Hosokawa, M; Matsushita, K; Moriuchi, T; Nakata, D; Shibata, T	1
Barry, E; Box, G; Eccles, S; McKenzie, E; Page, MJ; Patel, S; Rohlff, CR; Stamps, A; Stubberfield, C; Terrett, J; Turner, PR; Tyson, K; Young, K	1
Beech, DJ; Deng, N; Madan, AK	1
Cameron, E; Leibovitz, B; Pauling, L	1
Foucar, E; Weidner, N	1

Reviews

6 review(s) available for hyaluronoglucosaminidase and Invasiveness, Neoplasm

Article	Year
The role of CEMIP in tumors: An update based on cellular and molecular insights. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 146 Topics: Biomarkers, Tumor; Cell Movement; Cell Proliferation; ErbB Receptors; Humans; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Signal Transduction; Tumor Microenvironment; Wnt Proteins	2022
The matrix in cancer. Nature reviews. Cancer, 2021, Volume: 21, Issue:4 Topics: ADAM Proteins; ADAMTS Proteins; Bone Morphogenetic Protein 1; Cathepsins; Cell Movement; Collagen; Cystatins; Elastin; Extracellular Matrix; Extracellular Matrix Proteins; Fibrillins; Glucuronidase; Glycoproteins; Humans; Hyaluronoglucosaminidase; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Protein Processing, Post-Translational; Proteoglycans; Serpins; Tissue Inhibitor of Metalloproteinases; Tolloid-Like Metalloproteinases; Tumor Microenvironment	2021
Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:8 Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Progression; Extracellular Matrix; Growth Substances; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Tumor Cells, Cultured	2003
Hyaluronan: from extracellular glue to pericellular cue. Nature reviews. Cancer, 2004, Volume: 4, Issue:7 Topics: Adult; Animals; Cell Survival; Connective Tissue; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Embryonic and Fetal Development; Extracellular Matrix; Forecasting; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Inflammation; Joints; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Signal Transduction; Ultrasonography; Wound Healing; Xenograft Model Antitumor Assays	2004
Hyaluronidases in tissue invasion. Invasion & metastasis, 1997, Volume: 17, Issue:6 Topics: Animals; Bacterial Proteins; Bacteriophages; Eukaryota; Extracellular Matrix; Fungi; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Invertebrates; Leeches; Neoplasm Invasiveness; Substrate Specificity; Venoms; Viruses	1997
Ascorbic acid and cancer: a review. Cancer research, 1979, Volume: 39, Issue:3 Topics: Animals; Ascorbic Acid; Carcinogens; Collagen; Extracellular Space; History, 18th Century; History, 20th Century; Humans; Hyaluronoglucosaminidase; Immunity; Neoplasm Invasiveness; Neoplasms; Pituitary-Adrenal System; Scurvy	1979

Other Studies

47 other study(ies) available for hyaluronoglucosaminidase and Invasiveness, Neoplasm

Article	Year
Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression. BMC cancer, 2022, Feb-17, Volume: 22, Issue:1 Topics: Biomarkers, Tumor; Breast Neoplasms; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Loss of Function Mutation; Matrix Metalloproteinases, Membrane-Associated; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Processes; Phenotype; Prognosis; Repressor Proteins; RNA, Messenger; Signal Transduction; Up-Regulation	2022
TMEM2 expression is downregulated as bladder cancer invades the muscle layer. Biochemical and biophysical research communications, 2022, 07-12, Volume: 613 Topics: Cell Line, Tumor; Cell Membrane; Epithelial-Mesenchymal Transition; Humans; Hyaluronoglucosaminidase; Membrane Proteins; Muscles; Neoplasm Invasiveness; Urinary Bladder Neoplasms	2022
KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT). Medical science monitor : international medical journal of experimental and clinical research, 2019, Sep-10, Volume: 25 Topics: Animals; Base Sequence; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Male; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Thyroid Cancer, Papillary; Up-Regulation	2019
Clinical Significance of KIAA1199 as a Novel Target for Gastric Cancer Drug Therapy. Anticancer research, 2019, Volume: 39, Issue:12 Topics: Aged; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Digestive System Surgical Procedures; Drug Combinations; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Male; Middle Aged; Neoplasm Invasiveness; Oxonic Acid; Prognosis; Stomach Neoplasms; Survival Analysis; Tegafur; Up-Regulation	2019
A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Patients with Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 07-01, Volume: 26, Issue:13 Topics: Alternative Splicing; Animals; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Hyaluronoglucosaminidase; Immunohistochemistry; Mice; Neoplasm Invasiveness; Prognosis; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2020
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis. Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:10 Topics: Aged; Cell Line, Tumor; Cell Movement; Female; Fluorescent Antibody Technique; Humans; Hyaluronoglucosaminidase; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Proteome; Retrospective Studies; Signal Transduction; Small Cell Lung Carcinoma	2020
Cell migration inducing hyaluronidase 1 (CEMIP) activates STAT3 pathway to facilitate cell proliferation and migration in breast cancer. Journal of receptor and signal transduction research, 2021, Volume: 41, Issue:2 Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Signal Transduction; STAT3 Transcription Factor	2021
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma. Aging, 2020, 11-10, Volume: 12, Issue:23 Topics: Animals; Bile Duct Neoplasms; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholangiocarcinoma; Databases, Genetic; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Retrospective Studies; Signal Transduction; Tumor Burden	2020
KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer. PloS one, 2017, Volume: 12, Issue:4 Topics: Aged; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Isoenzymes; Male; Matrix Metalloproteinase 2; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proteins; RNA, Small Interfering; Stomach Neoplasms; Survival Analysis; Wnt Signaling Pathway	2017
miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3. Cellular and molecular biology (Noisy-le-Grand, France), 2018, May-15, Volume: 64, Issue:6 Topics: Cell Adhesion Molecules; Cell Division; Cell Line, Tumor; Cell Movement; Eye Neoplasms; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hyaluronoglucosaminidase; Immunoglobulins; MicroRNAs; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Proteins; Recombinant Proteins; Retinoblastoma; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Stem Cell Assay	2018
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway. Oncogene, 2019, Volume: 38, Issue:7 Topics: Animals; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Hyaluronoglucosaminidase; Mice; Mice, Inbred NOD; Mice, SCID; Microtubules; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Phosphatase 2; Proteins; Stathmin	2019
KIAA1199 promotes invasion and migration in non-small-cell lung cancer (NSCLC) via PI3K-Akt mediated EMT. Journal of molecular medicine (Berlin, Germany), 2019, Volume: 97, Issue:1 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Lung Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction	2019
The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer. Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:10 Topics: Aged; Cell Adhesion Molecules; Cell Movement; Colorectal Neoplasms; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; HCT116 Cells; Humans; Hyaluronoglucosaminidase; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Signal Transduction; Stress Fibers; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2	2019
Functional role of long non-coding RNA CASC19/miR-140-5p/CEMIP axis in colorectal cancer progression World journal of gastroenterology, 2019, Apr-14, Volume: 25, Issue:14 Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colon; Colorectal Neoplasms; Disease Progression; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Kaplan-Meier Estimate; Male; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Proteins; RNA, Long Noncoding; Up-Regulation	2019
Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors. PloS one, 2013, Volume: 8, Issue:7 Topics: Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Shape; Colorectal Neoplasms; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Protein Binding; Protein Transport; Proteins; RNA, Messenger; Wnt Signaling Pathway	2013
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness. BMC cancer, 2014, Mar-15, Volume: 14 Topics: Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hyaluronoglucosaminidase; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Proteins; Proteomics	2014
A novel role of low molecular weight hyaluronan in breast cancer metastasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:4 Topics: Antigens, Neoplasm; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Extracellular Matrix; Female; Glucuronosyltransferase; GPI-Linked Proteins; Histone Acetyltransferases; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; MCF-7 Cells; Middle Aged; Molecular Weight; Neoplasm Invasiveness; Up-Regulation	2015
Association between KIAA1199 overexpression and tumor invasion, TNM stage, and poor prognosis in colorectal cancer. International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Colorectal Neoplasms; Female; Humans; Hyaluronoglucosaminidase; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Prognosis; Proportional Hazards Models; Proteins; Real-Time Polymerase Chain Reaction; Up-Regulation; Young Adult	2015
Down-regulation of KIAA1199/CEMIP by miR-216a suppresses tumor invasion and metastasis in colorectal cancer. International journal of cancer, 2017, 05-15, Volume: 140, Issue:10 Topics: Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Liver Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Neoplastic Stem Cells; Prognosis; Proteins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
Editorial comment on: HYAL-1 hyaluronidase: a potential prognostic indicator for progression to muscle invasion and recurrence in bladder cancer. European urology, 2010, Volume: 57, Issue:1 Topics: Biomarkers, Tumor; Disease Progression; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Immunohistochemistry; Muscle, Smooth; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Risk Assessment; Risk Factors; Time Factors; Tissue Array Analysis; Treatment Outcome; Urinary Bladder Neoplasms	2010
HYAL-1 hyaluronidase: a potential prognostic indicator for progression to muscle invasion and recurrence in bladder cancer. European urology, 2010, Volume: 57, Issue:1 Topics: Aged; Biomarkers, Tumor; Disease Progression; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Immunohistochemistry; Kaplan-Meier Estimate; Logistic Models; Male; Muscle, Smooth; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Tissue Array Analysis; Treatment Outcome; Urinary Bladder Neoplasms	2010
Comparison of hyaluronidase expression, invasiveness and tubule formation promotion in ER (-) and ER (+) breast cancer cell lines in vitro. Chinese medical journal, 2009, Jun-05, Volume: 122, Issue:11 Topics: Breast Neoplasms; Cathepsin D; Cell Line, Tumor; Humans; Hyaluronoglucosaminidase; Immunohistochemistry; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Receptors, Estrogen; Vascular Endothelial Growth Factor A	2009
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer. International journal of cancer, 2011, Mar-15, Volume: 128, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Movement; Cell Proliferation; Disease Progression; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Umbilical Veins; Xenograft Model Antitumor Assays	2011
Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells. Cancer letters, 2010, Dec-08, Volume: 298, Issue:2 Topics: Animals; Bacteriophages; Breast Neoplasms; Cattle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Immunoblotting; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Neoplasm Invasiveness; Oligosaccharides; rhoA GTP-Binding Protein	2010
Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells. Cancer research, 2011, Jun-15, Volume: 71, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Male; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A	2011
Upregulation of HYAL1 expression in breast cancer promoted tumor cell proliferation, migration, invasion and angiogenesis. PloS one, 2011, Volume: 6, Issue:7 Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Female; Flow Cytometry; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; NIH 3T3 Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Umbilical Veins; Up-Regulation; Wound Healing	2011
Increased hyaluronan levels and decreased dendritic cell activation are associated with tumor invasion in murine lymphoma cell lines. Immunobiology, 2012, Volume: 217, Issue:9 Topics: Animals; Cell Line, Tumor; Dendritic Cells; Glucuronosyltransferase; Hyaluronic Acid; Hyaluronoglucosaminidase; Lymphoma; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness	2012
Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels. PloS one, 2012, Volume: 7, Issue:11 Topics: Biotinylation; Blotting, Western; Cell Migration Assays; Cell Surface Extensions; Extracellular Matrix Proteins; Gene Knockdown Techniques; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogels; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Rheology; Trypan Blue; Tumor Cells, Cultured	2012
Cell membrane glycosylation mediates the adhesion, migration, and invasion of ovarian carcinoma cells. Clinical & experimental metastasis, 2003, Volume: 20, Issue:2 Topics: Cell Adhesion; Cell Movement; Chondroitin ABC Lyase; Chondroitin Sulfates; Collagen Type IV; Extracellular Matrix; Female; Fibronectins; Gene Expression Profiling; Glycosylation; Humans; Hyaluronoglucosaminidase; Laminin; Membrane Glycoproteins; Neoplasm Invasiveness; Neuraminidase; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Proteoglycans; RNA, Messenger; Tumor Cells, Cultured	2003
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26 Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Immunoglobulin G; Intracellular Signaling Peptides and Proteins; Lysosomes; Membrane Microdomains; Membrane Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers	2004
Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D. Matrix biology : journal of the International Society for Matrix Biology, 2004, Volume: 23, Issue:3 Topics: Binding Sites; Biocompatible Materials; Cell Line, Tumor; Cell Movement; Heparin; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogel, Polyethylene Glycol Dimethacrylate; Neoplasm Invasiveness; Neoplasms; Neuraminidase	2004
[Inhibitory effect of hyaluronic acid, hyaluronidase and RGD on adhesion and invasion of human gastric cancer cell line SGC7901]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2004, Volume: 26, Issue:5 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Drug Synergism; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Integrin beta1; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; Oligopeptides; Stomach Neoplasms	2004
HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion. Cancer research, 2005, Mar-15, Volume: 65, Issue:6 Topics: Apoptosis; Carcinoma, Transitional Cell; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Extracellular Matrix; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Transfection; Transplantation, Heterologous; Urinary Bladder Neoplasms	2005
The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer. Experimental cell research, 2005, Oct-15, Volume: 310, Issue:1 Topics: Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Glucuronosyltransferase; Glycocalyx; GPI-Linked Proteins; Humans; Hyaluronan Receptors; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Isoenzymes; Molecular Weight; Neoplasm Invasiveness; RNA, Messenger; Up-Regulation	2005
Elevation of hyaluronidase-1 and soluble intercellular adhesion molecule-1 helps select bladder cancer patients at risk of invasion. Archives of medical research, 2006, Volume: 37, Issue:1 Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Humans; Hyaluronoglucosaminidase; Intercellular Adhesion Molecule-1; Male; Neoplasm Invasiveness; Predictive Value of Tests; Risk Factors; Urinary Bladder Neoplasms	2006
WW domain-containing oxidoreductase: a candidate tumor suppressor. Trends in molecular medicine, 2007, Volume: 13, Issue:1 Topics: Biomarkers; Cell Differentiation; DNA-Binding Proteins; Gene Components; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Hyaluronoglucosaminidase; Models, Biological; Neoplasm Invasiveness; Nuclear Proteins; Oxidoreductases; Phosphorylation; Protein Structure, Tertiary; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase	2007
Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells. International journal of cancer, 2007, Jun-15, Volume: 120, Issue:12 Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Isoenzymes; Neoplasm Invasiveness; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection	2007
Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis. The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28 Topics: Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Male; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Prostatic Neoplasms	2007
Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent. Journal of immunology (Baltimore, Md. : 1950), 1995, May-15, Volume: 154, Issue:10 Topics: Animals; Carrier Proteins; Female; Flow Cytometry; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Immunoglobulin Fab Fragments; Lymph Nodes; Lymphoma, T-Cell; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Receptors, Cell Surface; Receptors, Lymphocyte Homing; Splenic Neoplasms; Tumor Cells, Cultured	1995
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-23, Volume: 93, Issue:15 Topics: Animals; Base Sequence; Cell Division; Chamomile; Colonic Neoplasms; Cornea; DNA Primers; Enzyme Inhibitors; Female; Flavonoids; Glioblastoma; Glioma; Humans; Hyaluronoglucosaminidase; Melanoma; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Oils, Volatile; Plants, Medicinal; Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured	1996
Secretion of bladder tumor-derived hyaluronidase activity by invasive bladder tumor cells. Cancer letters, 1998, Sep-11, Volume: 131, Issue:1 Topics: Adult; Aged; Enzyme-Linked Immunosorbent Assay; Humans; Hyaluronoglucosaminidase; Middle Aged; Neoplasm Invasiveness; Tissue Extracts; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1998
Hyaluronidase-2 overexpression accelerates intracerebral but not subcutaneous tumor formation of murine astrocytoma cells. Cancer research, 1999, Dec-15, Volume: 59, Issue:24 Topics: Animals; Astrocytoma; Brain Neoplasms; Cell Division; Glioma; Hyaluronan Receptors; Hyaluronoglucosaminidase; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; RNA, Messenger; Skin Neoplasms	1999
Significance of VLA-4-VCAM-1 interaction and CD44 for transendothelial invasion in a bone marrow metastatic myeloma model. Clinical & experimental metastasis, 1999, Volume: 17, Issue:7 Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Cells; Cell Adhesion; Cell Line; Coculture Techniques; Endothelium; Female; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Integrin alpha4beta1; Integrins; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasm Invasiveness; Neoplasm Proteins; Receptors, Lymphocyte Homing; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	1999
Enhancement of tumorigenic, metastatic and in vitro invasive capacity of rat mammary tumor cells by transforming growth factor-beta. Cancer letters, 2002, Jan-10, Volume: 175, Issue:1 Topics: Animals; Antibodies; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chemotaxis; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Immediate-Early Proteins; Kinetics; Mammary Neoplasms, Experimental; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Trans-Activators; Transforming Growth Factor beta; Xenopus Proteins	2002
Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer. International journal of cancer, 2002, Feb-01, Volume: 97, Issue:4 Topics: Adenocarcinoma; Animals; Breast; Breast Neoplasms; Enzyme Induction; Female; Gene Expression Profiling; Genes; Humans; Hyaluronoglucosaminidase; Male; Mice; Mice, Nude; Multigene Family; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Organ Specificity; Prostatic Neoplasms; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Subcellular Fractions; Testis; Transplantation, Heterologous; Tumor Cells, Cultured	2002
Expression of PH-20 in normal and neoplastic breast tissue. The Journal of surgical research, 2002, Volume: 103, Issue:2 Topics: Biomarkers, Tumor; Black People; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Adhesion Molecules; Female; Humans; Hyaluronoglucosaminidase; Lymphatic Metastasis; Neoplasm Invasiveness; Prognosis; Racial Groups; Reverse Transcriptase Polymerase Chain Reaction; RNA	2002
Adenosquamous carcinoma of the skin. An aggressive mucin- and gland-forming squamous carcinoma. Archives of dermatology, 1985, Volume: 121, Issue:6 Topics: Adenocarcinoma; Carcinoembryonic Antigen; Carcinoma, Squamous Cell; Cell Differentiation; Face; Histocytochemistry; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Male; Middle Aged; Mucins; Neoplasm Invasiveness; Neuraminidase; Skin Neoplasms; Staining and Labeling	1985