Page last updated: 2024-08-22

hyaluronoglucosaminidase and Breast Cancer

hyaluronoglucosaminidase has been researched along with Breast Cancer in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (8.62)	18.7374
1990's	4 (6.90)	18.2507
2000's	14 (24.14)	29.6817
2010's	21 (36.21)	24.3611
2020's	14 (24.14)	2.80

Authors

Authors	Studies
Chennathukuzhi, VM; Cloud, AS; Ganeshkumar, S; Gunewardena, S; Jensen, RA; Kumaraswamy, E; Shimak, RM; Vargheese, AM	1
Carvalho, AM; Gomes, M; Novoa-Carballal, R; Pashkuleva, I; Reis, RL; Soares da Costa, D; Valcarcel, J; Vázquez, JA	1
Chen, M; Ge, X; Liu, J; Ma, Q; Tang, Y; Wen, Q; Zhang, L; Zhao, M; Zhu, L	1
Duco, MR; Murdock, JL; Reeves, DJ	1
Chen, W; He, J; Hsieh, IY; Li, F; Li, J; Liang, Z; Lin, B; Lu, B; Lu, G; Lv, W; Wang, L; Zhao, W	1
Chen, H; Cui, S; Du, J; Fan, X; Lan, H; Zhang, E; Zhang, S; Zhang, Z; Zhao, Y; Zhen, Y; Zhi, D	1
Chen, Y; Li, L; Zhang, J	1
Abukhdeir, AM; Amiri-Kordestani, L; Beaver, JA; Bhatnagar, V; Bloomquist, EW; Chiu, HJ; Gao, JJ; Ghosh, S; Gong, Y; Hou, S; Jiang, X; Kluetz, PG; Osgood, CL; Pazdur, R; Philip, R; Pierce, WF; Qiu, J; Rahman, NA; Ricks, TK; Rizvi, F; Seidman, J; Song, P; Wilson, W; Yu, J; Zhang, H	1
Badovinac Crnjevic, T; Colomer, R; De Laurentiis, M; Heeson, S; Hogea, A; Im, SA; Jackisch, C; Jung, KH; Kirschbrown, WP; Mattar, A; Nowecki, Z; Pierga, JY; Restuccia, E; Schem, C; Shivhare, M; Stroyakovskii, D; Tan, AR	1
Brundel, DH; Feeney, OM; Gracia, G; Kaminskas, LM; Kang, DW; McIntosh, MM; Nowell, CJ; Porter, CJ; Suys, EJ	1
Li, H; Rong, J; Yang, Y; Zhao, J; Zhou, F; Zhuang, S	1
Chen, H; Han, L; Ju, X; Miao, T; Ni, J	1
Baldovino, S; Radin, M; Roccatello, D; Sciascia, S	1
Du, J; Hua, Z; Jiao, M; Ju, C; Wang, Q; Xie, D; Xue, L; Zhang, C; Zhou, A	1
Gao, H; He, X; Liu, R; Qin, L; Xiao, W; Xie, R; Yang, X; Yang, Z; Yu, W	1
Bahou, WF; Cao, J; Dufour, A; Evensen, NA; Hu, YJ; Kadam, P; Kuscu, C; Nguyen, HL; Pulkoski-Gross, A; Zarrabi, K; Zucker, S	1
Ding, SJ; Dong, J; Fu, K; Geng, L; Hassan, H; Hou, J; Huang, X; Jami, MS; Li, Y; Liu, M; Peng, H; Singh, RK; Varney, ML; Wang, J; Yu, F	1
Bartram, CR; Brenner, H; Bugert, P; Burwinkel, B; Claus, R; Cuk, K; Engel, C; Hoth, M; Marme, F; Pfütze, K; Plass, C; Qu, B; Schmutzler, R; Schneeweiss, A; Schott, S; Sohn, C; Sutter, C; Wappenschmidt, B; Yang, R; Zucknick, M	1
Schmaus, A; Sleeman, JP	1
Cao, M; Du, Y; Gao, F; He, Y; Liu, Y; Wang, W; Wu, M; Yang, C	1
Bomba, HN; Gu, Z; Hu, Q; Isaacson, AJ; Jiang, T; Lu, Y; Sun, W; Ye, Y	1
Benhadjeba, S; Carmona, E; Edjekouane, L; Fleury, H; Gévry, N; Jangal, M; Tremblay, A	1
Hadrian, R; Palmes, D	1
Laakmann, E; Marx, AK; Matschke, J; Milde-Langosch, K; Müller, V; Oliveira-Ferrer, L; Prehm, P; Schmalfeldt, B; Schumacher, U; Stürken, C; Wikman, H; Witzel, I	1
Acharya, A; Chen, XB; Guo, K; Hou, XL; Li, CF; Lin, FH; Nie, Y; Qiao, SP; Shi, SL; Tian, WM; Yao, LF; Zhao, YF	1
Feng, L; Gao, R; Gopalakrishnakone, P	1
Delpech, B; Ren, GS; Tan, JX; Vasse, M; Wang, XY	1
Li, HY; Ran, L; Ren, GS; Su, XL; Tan, JX; Wang, L; Wang, XY; Zheng, K	1
Bao, JJ; Fang, CH; Wu, WD; Yang, ZX	1
Deivanayagam, C; Kumar, S; Lee, JH; Moore, LD; Ponnazhagan, S; Pritchard, DG	1
Bernaciak, M; Bryś, M; Forma, E; Krześlak, A; Romanowicz, H	1
Li, HY; Ren, GS; Shi, Y; Su, XL; Tan, JX; Wang, L; Wang, XY	1
Cao, J; Evensen, N; Hu, YJ; Kim, D; Kuscu, C; Zucker, S	1
Banerjee, SD; Kollapalli, SP; Mortha, KK; Srinivas, P; Thomas, A	1
LACASSAGNE, A; LOISELEUR, J; RUDALI, G	2
Bourguignon, LY; Diedrich, F; Gilad, E; Singleton, PA; Stern, R	1
Chen, JG; Ding, HY; Ning, HY; Underhill, CB; Wang, LP; Xu, XM; Yang, SM; Yu, JY; Zhang, LR	1
Brown, TJ; Brownlee, GR; Nilsson, SK; Udabage, L	1
Barrett, JC; Garcés, G; Horikawa, I; Michishita, E	1
Chen, J; Ding, I; Gao, F; Han, Z; Kim, S; Liu, W; Okunieff, P; Underhill, CB; Wang, L; Yang, S; Zhang, J; Zhang, L	1
Li, XT; Ran, L; Ren, GS; Tan, JX; Tu, G; Wang, XY	1
Brown, TJ; Heldin, P; Li, L; Li, Y	1
BITTNER, JJ; GLICK, D; GOOD, TA	1
Abraham, J; Bonney, G; Dewitty, RL; Lokeshwar, VB; Marshalleck, JJ; Poola, I; Yue, Q	1
Nishi, T; Saya, H; Tanabe, KK	1
Bertrand, P; Chauzy, C; d'Anjou, J; Delpech, B; Duval, C; Girard, N; Ménard, JF	1
Bormann, G; Fischer, M; Marsch, WC; Wohlrab, J	1
Bader, A; Egger, G; Glasner, A; Pfragner, R; Siegl, V; Steindorfer, P; Zatloukal, K	1
Barry, E; Box, G; Eccles, S; McKenzie, E; Page, MJ; Patel, S; Rohlff, CR; Stamps, A; Stubberfield, C; Terrett, J; Turner, PR; Tyson, K; Young, K	1
Beech, DJ; Deng, N; Madan, AK	1
Gao, F; Underhill, CB; Zhang, L	1
Azzopardi, JG; Gad, A	1
Koláŏvá, M	1
Bannke, S; Beckenlehner, K; Bernhardt, G; Schiess, W; Schönenberg, H; Spruss, T	1

Reviews

3 review(s) available for hyaluronoglucosaminidase and Breast Cancer

Article	Year
Trastuzumab/Hyaluronidase-oysk: A New Option for Patients With HER2-Positive Breast Cancer. The Annals of pharmacotherapy, 2020, Volume: 54, Issue:3 Topics: Adult; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease-Free Survival; Female; Humans; Hyaluronoglucosaminidase; Injections, Intravenous; Injections, Subcutaneous; Middle Aged; Receptor, ErbB-2; Trastuzumab	2020
In brief: Phesgo - a fixed-dose combination for HER-2 positive breast cancer. The Medical letter on drugs and therapeutics, 2021, 03-08, Volume: 63, Issue:1619 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Drug Combinations; Female; Humans; Hyaluronoglucosaminidase; Neoadjuvant Therapy; Receptor, ErbB-2; Trastuzumab	2021
Animal Models of Secondary Lymphedema: New Approaches in the Search for Therapeutic Options. Lymphatic research and biology, 2017, Volume: 15, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Cytokines; Disease Models, Animal; Female; Haplorhini; Humans; Hyaluronoglucosaminidase; Intercellular Signaling Peptides and Proteins; Lymphatic Vessels; Lymphedema; Lymphography; Lymphoscintigraphy; Molecular Targeted Therapy; Rabbits; Rodentia; Sheep; Stem Cells; Surgical Procedures, Operative; Swine; Vascular Endothelial Growth Factor C	2017

Trials

1 trial(s) available for hyaluronoglucosaminidase and Breast Cancer

Article	Year
Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiority, phase 3 study. The Lancet. Oncology, 2021, Volume: 22, Issue:1 Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Hyaluronoglucosaminidase; Injections, Subcutaneous; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Receptor, ErbB-2; Time Factors; Trastuzumab; Treatment Outcome	2021

Article

Year

Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiority, phase 3 study.

The Lancet. Oncology, 2021, Volume: 22, Issue:1

Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Hyaluronoglucosaminidase; Injections, Subcutaneous; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Receptor, ErbB-2; Time Factors; Trastuzumab; Treatment Outcome

2021

Other Studies

54 other study(ies) available for hyaluronoglucosaminidase and Breast Cancer

Article	Year
Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression. BMC cancer, 2022, Feb-17, Volume: 22, Issue:1 Topics: Biomarkers, Tumor; Breast Neoplasms; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Hyaluronoglucosaminidase; Loss of Function Mutation; Matrix Metalloproteinases, Membrane-Associated; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Processes; Phenotype; Prognosis; Repressor Proteins; RNA, Messenger; Signal Transduction; Up-Regulation	2022
Hyaluronan Brush-like Copolymers Promote CD44 Declustering in Breast Cancer Cells. ACS applied materials & interfaces, 2022, Sep-21, Volume: 14, Issue:37 Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Methacrylates; Oximes; Polymers	2022
Hyaluronidase responsive second near-infrared fluorescent nanocomplex for combined HER2 blockade and chemotherapy of HER2+ breast cancer. Biomaterials advances, 2022, Volume: 141 Topics: Animals; Breast Neoplasms; Coloring Agents; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Mice; Neoplasm Recurrence, Local; Paclitaxel; Receptor, ErbB-2; Trastuzumab	2022
H3K27me3 loss plays a vital role in CEMIP mediated carcinogenesis and progression of breast cancer with poor prognosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 123 Topics: Animals; Benzazepines; Biomarkers, Tumor; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Histones; Humans; Hyaluronoglucosaminidase; Mice; Mice, Nude; Prognosis; Pyrimidines; RNA, Messenger	2020
Stimuli-Responsive Polysaccharide Enveloped Liposome for Targeting and Penetrating Delivery of survivin-shRNA into Breast Tumor. ACS applied materials & interfaces, 2020, May-13, Volume: 12, Issue:19 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chitosan; Gene Transfer Techniques; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Liposomes; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Polysaccharides; RNA, Small Interfering; Survivin; Xenograft Model Antitumor Assays	2020
Cell migration inducing hyaluronidase 1 (CEMIP) activates STAT3 pathway to facilitate cell proliferation and migration in breast cancer. Journal of receptor and signal transduction research, 2021, Volume: 41, Issue:2 Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Hyaluronoglucosaminidase; Neoplasm Invasiveness; Signal Transduction; STAT3 Transcription Factor	2021
Pertuzumab, Trastuzumab and Hyaluronidase-zzxf. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, Nov-16, Volume: 77, Issue:23 Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiomyopathies; Female; Fetal Diseases; Humans; Hyaluronoglucosaminidase; Lung Diseases; Pregnancy; Trastuzumab	2020
FDA Approval Summary: Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection for Subcutaneous Use in Patients with HER2-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 04-15, Volume: 27, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Approval; Female; Humans; Hyaluronoglucosaminidase; Injections, Subcutaneous; Middle Aged; Multicenter Studies as Topic; Neoadjuvant Therapy; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Trastuzumab; Treatment Outcome; United States; United States Food and Drug Administration	2021
Depolymerization of hyaluronan using PEGylated human recombinant hyaluronidase promotes nanoparticle tumor penetration. Nanomedicine (London, England), 2021, Volume: 16, Issue:4 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Mice; Nanoparticles; Polyethylene Glycols	2021
ATP/Hyals dually responsive core-shell hyaluronan/chitosan-based drug nanocarrier for potential application in breast cancer therapy. International journal of biological macromolecules, 2021, Jul-31, Volume: 183 Topics: Adenosine Triphosphate; Breast Neoplasms; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; MCF-7 Cells; Nanoparticles; Quaternary Ammonium Compounds	2021
Prodrug Delivery Using Dual-Targeting Nanoparticles To Treat Breast Cancer Brain Metastases. Molecular pharmaceutics, 2021, 07-05, Volume: 18, Issue:7 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Cell Proliferation; Doxorubicin; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polyesters; Prodrugs; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2021
PEGPH20 May Improve Standard-of-Care Therapy in Pancreatic Cancer. Cancer discovery, 2018, Volume: 8, Issue:2 Topics: Adenocarcinoma; Albumins; Breast Neoplasms; Deoxycytidine; Gemcitabine; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Paclitaxel; Pancreatic Neoplasms	2018
Facilitated subcutaneous immunoglobulin treatment in pemphigus vulgaris. BMJ case reports, 2018, May-30, Volume: 2018 Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Dermatologic Agents; Drug Administration Schedule; Drug Combinations; Female; Humans; Hyaluronoglucosaminidase; Immunoglobulins; Injections, Subcutaneous; Middle Aged; Mouth Diseases; Mouth Mucosa; Pemphigus; Treatment Outcome	2018
Co-delivery of TRAIL and siHSP70 using hierarchically modular assembly formulations achieves enhanced TRAIL-resistant cancer therapy. Journal of controlled release : official journal of the Controlled Release Society, 2019, 06-28, Volume: 304 Topics: A549 Cells; Animals; Breast Neoplasms; Cell Line, Tumor; Female; HSP70 Heat-Shock Proteins; Humans; Hyaluronoglucosaminidase; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mice, Nude; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays	2019
Sequentially responsive biomimetic nanoparticles with optimal size in combination with checkpoint blockade for cascade synergetic treatment of breast cancer and lung metastasis. Biomaterials, 2019, Volume: 217 Topics: Animals; B7-H1 Antigen; Biomimetic Materials; Breast Neoplasms; Cations; Cell Death; Cell Line, Tumor; Endocytosis; Female; Gold; Humans; Hyaluronoglucosaminidase; Immunotherapy; Lung Neoplasms; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Paclitaxel; Particle Size; Peptides; RAW 264.7 Cells; Reactive Oxygen Species; Tissue Distribution	2019
Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration. Journal of the National Cancer Institute, 2013, Sep-18, Volume: 105, Issue:18 Topics: Animals; Blotting, Western; Breast Neoplasms; Calcium; Cell Movement; Disease Progression; Endoplasmic Reticulum; Epithelial-Mesenchymal Transition; Fluorescence Recovery After Photobleaching; Fluorescence Resonance Energy Transfer; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hyaluronoglucosaminidase; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Protein Kinase C-alpha; Proteins; Signal Transduction; Spectrometry, Fluorescence; Up-Regulation	2013
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness. BMC cancer, 2014, Mar-15, Volume: 14 Topics: Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hyaluronoglucosaminidase; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Proteins; Proteomics	2014
DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood. International journal of cancer, 2015, Apr-15, Volume: 136, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cell Adhesion Molecules; CpG Islands; DNA Methylation; Early Detection of Cancer; Female; Genetic Predisposition to Disease; GPI-Linked Proteins; Humans; Hyaluronoglucosaminidase; Middle Aged; Oligonucleotide Array Sequence Analysis; Young Adult	2015
Hyaluronidase-1 expression promotes lung metastasis in syngeneic mouse tumor models without affecting accumulation of small hyaluronan oligosaccharides in tumor interstitial fluid. Glycobiology, 2015, Volume: 25, Issue:3 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Extracellular Fluid; Hyaluronic Acid; Hyaluronoglucosaminidase; Lung Neoplasms; Mice	2015
A novel role of low molecular weight hyaluronan in breast cancer metastasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:4 Topics: Antigens, Neoplasm; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Extracellular Matrix; Female; Glucuronosyltransferase; GPI-Linked Proteins; Histone Acetyltransferases; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; MCF-7 Cells; Middle Aged; Molecular Weight; Neoplasm Invasiveness; Up-Regulation	2015
Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots. Nano letters, 2016, Feb-10, Volume: 16, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Drug Delivery Systems; Endosomes; Gene Transfer Techniques; Humans; Hyaluronoglucosaminidase; Mice; Snake Venoms; TNF-Related Apoptosis-Inducing Ligand; Tumor Microenvironment; Xenograft Model Antitumor Assays	2016
Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells. Oncotarget, 2016, 11-22, Volume: 7, Issue:47 Topics: Binding Sites; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Chromosomes, Human, Pair 3; Databases, Genetic; Down-Regulation; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Hyaluronoglucosaminidase; MCF-7 Cells; Multigene Family; Promoter Regions, Genetic; Sp1 Transcription Factor	2016
Role of HYAL1 expression in primary breast cancer in the formation of brain metastases. Breast cancer research and treatment, 2017, Volume: 162, Issue:3 Topics: Adult; Aged; Biomarkers; Brain Neoplasms; Breast Neoplasms; Cohort Studies; Female; Gene Expression; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Middle Aged; Neoplasm Grading; Neoplasm Staging; RNA, Messenger	2017
Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior. ACS applied materials & interfaces, 2017, Mar-22, Volume: 9, Issue:11 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Molecular Weight; Neoplasm Proteins; Tumor Microenvironment	2017
Isolation and characterization of a hyaluronidase from the venom of Chinese red scorpion Buthus martensi. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2008, Volume: 148, Issue:3 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Enzyme Stability; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Scorpion Venoms; Scorpions; Temperature	2008
Comparison of hyaluronidase expression, invasiveness and tubule formation promotion in ER (-) and ER (+) breast cancer cell lines in vitro. Chinese medical journal, 2009, Jun-05, Volume: 122, Issue:11 Topics: Breast Neoplasms; Cathepsin D; Cell Line, Tumor; Humans; Hyaluronoglucosaminidase; Immunohistochemistry; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Receptors, Estrogen; Vascular Endothelial Growth Factor A	2009
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer. International journal of cancer, 2011, Mar-15, Volume: 128, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Movement; Cell Proliferation; Disease Progression; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Umbilical Veins; Xenograft Model Antitumor Assays	2011
[Effects of SiRNA-EGFR on the expression of hyaluronidase gene EGFR in human breast cancer cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:6 Topics: Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female; Humans; Hyaluronoglucosaminidase; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection	2010
Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells. Cancer letters, 2010, Dec-08, Volume: 298, Issue:2 Topics: Animals; Bacteriophages; Breast Neoplasms; Cattle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Immunoblotting; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Neoplasm Invasiveness; Oligosaccharides; rhoA GTP-Binding Protein	2010
Gene expression of O-GlcNAc cycling enzymes in human breast cancers. Clinical and experimental medicine, 2012, Volume: 12, Issue:1 Topics: Acetylglucosamine; Adult; Aged; Antigens, Neoplasm; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Lymph Nodes; Middle Aged; N-Acetylglucosaminyltransferases; Neoplasm Grading; RNA, Messenger; Statistics, Nonparametric	2012
Upregulation of HYAL1 expression in breast cancer promoted tumor cell proliferation, migration, invasion and angiogenesis. PloS one, 2011, Volume: 6, Issue:7 Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Female; Flow Cytometry; Humans; Hyaluronoglucosaminidase; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; NIH 3T3 Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Umbilical Veins; Up-Regulation; Wound Healing	2011
Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer. PloS one, 2012, Volume: 7, Issue:9 Topics: Base Sequence; Breast Neoplasms; DNA; Epigenesis, Genetic; Female; Gene Silencing; Humans; Hyaluronoglucosaminidase; Molecular Sequence Data; Promoter Regions, Genetic; Proteins; Real-Time Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Transcription, Genetic	2012
Bioactive hyaluronan fragment (hexasaccharide) detects specific hexa-binding proteins in human breast and stomach cancer: possible role in tumorogenesis. Indian journal of biochemistry & biophysics, 2012, Volume: 49, Issue:4 Topics: Breast Neoplasms; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Oligosaccharides; Receptors, Cell Surface; Stomach Neoplasms; Substrate Specificity	2012
[Inverse effects of hyaluronidase and antihyaluronidase serum on the development of mammary carcinoma in the mouse]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1957, Mar-18, Volume: 244, Issue:12 Topics: Animals; Antibodies; Breast Neoplasms; Humans; Hyaluronoglucosaminidase; Immune Sera; Mice; Neoplasms, Experimental	1957
[Effect of spreading factors on the development of mouse mammary carcinoma]. Bulletin de l'Association francaise pour l'etude du cancer, 1957, Volume: 44, Issue:4 Topics: Animals; Breast; Breast Neoplasms; Humans; Hyaluronoglucosaminidase; Mice; Neoplasms, Experimental; Polysaccharide-Lyases; Venoms	1957
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26 Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Immunoglobulin G; Intracellular Signaling Peptides and Proteins; Lysosomes; Membrane Microdomains; Membrane Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers	2004
[Expression of PH20 in primary and metastatic breast cancer and its pathological significance]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 2004, Volume: 33, Issue:4 Topics: Adenocarcinoma, Mucinous; Adult; Animals; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Adhesion Molecules; Female; Humans; Hyaluronoglucosaminidase; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Rabbits; RNA, Messenger	2004
The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer. Experimental cell research, 2005, Oct-15, Volume: 310, Issue:1 Topics: Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Glucuronosyltransferase; Glycocalyx; GPI-Linked Proteins; Humans; Hyaluronan Receptors; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Isoenzymes; Molecular Weight; Neoplasm Invasiveness; RNA, Messenger; Up-Regulation	2005
Upregulation of the KIAA1199 gene is associated with cellular mortality. Cancer letters, 2006, Jul-28, Volume: 239, Issue:1 Topics: Breast Neoplasms; Carcinoma, Renal Cell; Cell Division; Cell Transformation, Neoplastic; Cellular Senescence; Chromosomes, Human, Pair 3; Female; Fibroblasts; Gene Expression Regulation; Humans; Hyaluronoglucosaminidase; Kidney Neoplasms; Male; Prostatic Neoplasms; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation	2006
Hypoxia-induced alterations in hyaluronan and hyaluronidase. Advances in experimental medicine and biology, 2005, Volume: 566 Topics: Acetylglucosaminidase; Animals; Antigens, Neoplasm; beta-N-Acetylhexosaminidases; Breast Neoplasms; Cell Line, Tumor; Female; Fibrosarcoma; Histone Acetyltransferases; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Hypoxia; Mice; Mice, Inbred C3H; Molecular Weight; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic	2005
[Effect of silencing of hyaluronidase gene HYAL1 by RNA interference on proliferation of human breast cancer cells]. Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:7 Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Genetic Therapy; Humans; Hyaluronoglucosaminidase; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection	2006
Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells. International journal of cancer, 2007, Jun-15, Volume: 120, Issue:12 Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Hyaluronoglucosaminidase; Isoenzymes; Neoplasm Invasiveness; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection	2007
Mucolytic enzyme systems; relationship of hyaluronidase inhibition by blood serum to incidence of mammary cancer in mice. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1948, Volume: 69, Issue:3 Topics: Animals; Breast Neoplasms; Expectorants; Hematologic Neoplasms; Humans; Hyaluronoglucosaminidase; Incidence; Mice; Neoplasms; Serum	1948
Molecular risk assessment for breast cancer development in patients with ductal hyperplasias. Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Feb-15, Volume: 14, Issue:4 Topics: Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Gene Expression; Humans; Hyaluronoglucosaminidase; Hyperplasia; Immunohistochemistry; Precancerous Conditions; Predictive Value of Tests; Retrospective Studies; Risk Assessment; ROC Curve	2008
Novel variants of CD44 arising from alternative splicing: changes in the CD44 alternative splicing pattern of MCF-7 breast carcinoma cells treated with hyaluronidase. Molecular carcinogenesis, 1993, Volume: 7, Issue:4 Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Blotting, Southern; Breast Neoplasms; Cloning, Molecular; DNA, Neoplasm; Female; Genetic Variation; Humans; Hyaluronoglucosaminidase; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, Lymphocyte Homing; Tumor Cells, Cultured	1993
Increased hyaluronidase levels in breast tumor metastases. International journal of cancer, 1997, Nov-04, Volume: 73, Issue:3 Topics: Breast Neoplasms; Female; Humans; Hyaluronoglucosaminidase; Lymphatic Metastasis; Neoplasm Proteins; Tumor Cells, Cultured	1997
[Radiation-induced morphea]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:7 Topics: Breast Neoplasms; Female; Humans; Hyaluronoglucosaminidase; Middle Aged; PUVA Therapy; Scleroderma, Localized; X-Rays	1999
The affinity of MCF7 breast cancer cells to hyaluronan substrates of different molecular weight and concentrations in an in vitro model. International journal of oncology, 2000, Volume: 17, Issue:5 Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Aggregation; Cells, Cultured; Female; Fibroblasts; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Microscopy, Electron, Scanning; Molecular Weight; Osmolar Concentration; Tumor Cells, Cultured	2000
Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer. International journal of cancer, 2002, Feb-01, Volume: 97, Issue:4 Topics: Adenocarcinoma; Animals; Breast; Breast Neoplasms; Enzyme Induction; Female; Gene Expression Profiling; Genes; Humans; Hyaluronoglucosaminidase; Male; Mice; Mice, Nude; Multigene Family; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Organ Specificity; Prostatic Neoplasms; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Subcellular Fractions; Testis; Transplantation, Heterologous; Tumor Cells, Cultured	2002
Expression of PH-20 in normal and neoplastic breast tissue. The Journal of surgical research, 2002, Volume: 103, Issue:2 Topics: Biomarkers, Tumor; Black People; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Adhesion Molecules; Female; Humans; Hyaluronoglucosaminidase; Lymphatic Metastasis; Neoplasm Invasiveness; Prognosis; Racial Groups; Reverse Transcriptase Polymerase Chain Reaction; RNA	2002
[Promotion of growth of human breast cancer cells MDA231 by human sperm membrane-bound hyaluronidase: an experimental study]. Zhonghua yi xue za zhi, 2002, Feb-10, Volume: 82, Issue:3 Topics: Animals; Aorta; Breast Neoplasms; Cattle; Cell Division; Chick Embryo; Disease Models, Animal; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Male; Membrane Proteins; Neoplasm Transplantation; Neovascularization, Pathologic; Spermatozoa; Transplantation, Heterologous; Tumor Cells, Cultured	2002
Lobular carcinoma of the breast: a special variant of mucin-secreting carcinoma. Journal of clinical pathology, 1975, Volume: 28, Issue:9 Topics: Adenocarcinoma, Mucinous; Breast Neoplasms; Carcinoma in Situ; Epithelial Cells; Female; Humans; Hyaluronoglucosaminidase; Mucins; Neuraminidase	1975
Host-tumor relationship. XXXIV. Hyaluronidase activity and hyaluronidase inhibitor in the serum of patients with malignant tumors. Neoplasma, 1977, Volume: 24, Issue:3 Topics: Breast Neoplasms; Chromatography, Gel; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Hyaluronoglucosaminidase; Lung Neoplasms; Melanoma; Neoplasms	1977
Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo. Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:8 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Doxorubicin; Drug Synergism; Female; Humans; Hyaluronoglucosaminidase; Mammary Neoplasms, Experimental; Mice	1992