Page last updated: 2024-10-21

huperzine a and Sepsis Associated Delirium

huperzine a has been researched along with Sepsis Associated Delirium in 2 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"To explore whether the cholinergic anti-inflammatory pathway is involved in the neuroprotective effect of acetylcholinesterase inhibitor huperzine A (HupA) on sepsis-associated encephalopathy (SAE) by observing the effect of HupA on the expressions of choline acetyltransferase (CHAT) and cholinergic muscarinic receptor M1 (CHRM1) of sepsis rats."7.83[Cholinergic anti-inflammatory pathway involves in the neuroprotective effect of huperzine A on sepsis-associated encephalopathy]. ( Han, Q; Han, Y; Huang, L; Huang, W; Liu, X; Xie, D; Zeng, H; Zhu, S, 2016)
"To explore whether the cholinergic anti-inflammatory pathway is involved in the neuroprotective effect of acetylcholinesterase inhibitor huperzine A (HupA) on sepsis-associated encephalopathy (SAE) by observing the effect of HupA on the expressions of choline acetyltransferase (CHAT) and cholinergic muscarinic receptor M1 (CHRM1) of sepsis rats."3.83[Cholinergic anti-inflammatory pathway involves in the neuroprotective effect of huperzine A on sepsis-associated encephalopathy]. ( Han, Q; Han, Y; Huang, L; Huang, W; Liu, X; Xie, D; Zeng, H; Zhu, S, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, W1
Zhu, S1
Liu, X1
Huang, L1
Han, Y1
Han, Q1
Xie, D1
Zeng, H1
Zhu, SZ1
Huang, WP1
Huang, LQ1
Han, YL1
Han, QP1
Zhu, GF1
Wen, MY1
Deng, YY1
Zeng, HK1

Other Studies

2 other studies available for huperzine a and Sepsis Associated Delirium

ArticleYear
[Cholinergic anti-inflammatory pathway involves in the neuroprotective effect of huperzine A on sepsis-associated encephalopathy].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:5

    Topics: Acetylcholine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Choline O-Acetyltransferase;

2016
Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.
    Neuroscience letters, 2016, Sep-19, Volume: 631

    Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Cholin

2016