huperzine a has been researched along with Neurodegenerative Diseases in 2 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Unfortunately, currently available treatments for neurodegenerative disorders can only relieve the symptoms but not modify the pathological processes." | 2.72 | Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget. ( Carlier, PR; Cui, W; Fu, H; Han, Y; Hu, S; Li, W; Luo, J; Mak, S; Pang, Y; Pi, R; Tsim, KW, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Villegas, C | 1 |
| Perez, R | 1 |
| Petiz, LL | 1 |
| Glaser, T | 1 |
| Ulrich, H | 1 |
| Paz, C | 1 |
| Mak, S | 1 |
| Li, W | 1 |
| Fu, H | 1 |
| Luo, J | 1 |
| Cui, W | 1 |
| Hu, S | 1 |
| Pang, Y | 1 |
| Carlier, PR | 1 |
| Tsim, KW | 1 |
| Pi, R | 1 |
| Han, Y | 1 |
2 reviews available for huperzine a and Neurodegenerative Diseases
| Article | Year |
|---|---|
Ginkgolides and Huperzine A for complementary treatment of Alzheimer's disease.
Topics: Activities of Daily Living; Alkaloids; Alzheimer Disease; Ginkgolides; Humans; Neurodegenerative Dis | 2022 |
Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget.
Topics: Acetylcholinesterase; Alkaloids; Animals; Cholinesterase Inhibitors; Drug Combinations; Drug Deliver | 2021 |