Page last updated: 2024-10-21

huperzine a and Inflammation

huperzine a has been researched along with Inflammation in 5 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Chronic pain is a major health issue and most patients suffer from spontaneous pain."5.42Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice. ( Feng, ZH; Li, XY; Liu, L; Mei, SH; Wang, M; Wang, Y; Wang, YJ; Zuo, ZX, 2015)
"Chronic pain is a major health issue and most patients suffer from spontaneous pain."1.42Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice. ( Feng, ZH; Li, XY; Liu, L; Mei, SH; Wang, M; Wang, Y; Wang, YJ; Zuo, ZX, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Guo, X1
Wu, Y1
Wang, Q1
Zhang, J1
Sheng, X1
Zheng, L1
Wang, Y2
Zuo, ZX1
Wang, YJ1
Liu, L1
Mei, SH1
Feng, ZH1
Wang, M1
Li, XY1
Wang, J1
Zhang, HY1
Tang, XC1
Ruan, Q1
Liu, F1
Gao, Z1
Kong, D1
Hu, X1
Shi, D1
Bao, Z1
Yu, Z1
Sivaprakasam, K1

Reviews

2 reviews available for huperzine a and Inflammation

ArticleYear
Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:7

    Topics: Acetylcholine; Alkaloids; Animals; Anti-Inflammatory Agents; Cholinergic Agents; Cholinesterase Inhi

2009
Towards a unifying hypothesis of Alzheimer's disease: cholinergic system linked to plaques, tangles and neuroinflammation.
    Current medicinal chemistry, 2006, Volume: 13, Issue:18

    Topics: Alkaloids; Alzheimer Disease; Amyloid; Cholinergic Fibers; Cholinesterase Inhibitors; Galantamine; I

2006

Other Studies

3 other studies available for huperzine a and Inflammation

ArticleYear
Huperzine A injection ameliorates motor and cognitive abnormalities via regulating multiple pathways in a murine model of Parkinson's disease.
    European journal of pharmacology, 2023, Oct-05, Volume: 956

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholinesterase; Animals; Cognition; Disease Mode

2023
Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice.
    Neural plasticity, 2015, Volume: 2015

    Topics: Acetylcholinesterase; Alkaloids; Ambenonium Chloride; Analgesics; Animals; Atropine; Behavior, Anima

2015
The anti-inflamm-aging and hepatoprotective effects of huperzine A in D-galactose-treated rats.
    Mechanisms of ageing and development, 2013, Volume: 134, Issue:3-4

    Topics: Aging; Alkaloids; Animals; Anti-Inflammatory Agents; Cellular Senescence; Cytokines; Galactose; Infl

2013