huperzine a has been researched along with Infarction, Middle Cerebral Artery in 1 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, which used a rat middle cerebral artery occlusion (MCAO) model, the protective effects of huperzine A (HupA) against mitochondrial dysfunction and brain damage were investigated." | 1.35 | Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats. ( Tang, XC; Zhang, HY; Zheng, CY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, CY | 1 |
| Zhang, HY | 1 |
| Tang, XC | 1 |
1 other study available for huperzine a and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats.
Topics: Alkaloids; Animals; Brain; Infarction, Middle Cerebral Artery; Male; Membrane Potential, Mitochondri | 2008 |