huperzine a has been researched along with Hypoxia-Ischemia, Brain in 3 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huperzine A treatment (0." | 1.32 | [Huperzine A attenuates cognitive deficits and brain injury after hypoxia-ischemic brain damage in neonatal rats]. ( Shao, XM; Tang, XC; Wang, LS; Zhou, J, 2003) |
| "Huperzine A was administrated daily at the dose of 0." | 1.31 | Huperzine A attenuates cognitive deficits and brain injury in neonatal rats after hypoxia-ischemia. ( Shao, XM; Tang, XC; Wang, LS; Zhou, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, LS | 2 |
| Zhou, J | 3 |
| Shao, XM | 2 |
| Tang, XC | 3 |
| Fu, Y | 1 |
3 other studies available for huperzine a and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Huperzine A attenuates cognitive deficits and brain injury in neonatal rats after hypoxia-ischemia.
Topics: Alkaloids; Animals; Animals, Newborn; Brain Injuries; Carotid Arteries; Cerebral Cortex; Cholinester | 2002 |
[Huperzine A attenuates cognitive deficits and brain injury after hypoxia-ischemic brain damage in neonatal rats].
Topics: Acetylcholinesterase; Alkaloids; Animals; Animals, Newborn; Cerebral Cortex; Cognition Disorders; Co | 2003 |
Huperzine A and donepezil protect rat pheochromocytoma cells against oxygen-glucose deprivation.
Topics: Alkaloids; Alzheimer Disease; Animals; Cell Size; Cell Survival; Cholinesterase Inhibitors; Donepezi | 2001 |