huperzine a has been researched along with Dementia, Vascular in 6 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabira, T | 1 |
| Kawamura, N | 1 |
| Zhang, HY | 2 |
| Zheng, CY | 1 |
| Yan, H | 2 |
| Wang, ZF | 1 |
| Tang, LL | 1 |
| Gao, X | 1 |
| Tang, XC | 3 |
| Hao, Z | 1 |
| Liu, M | 1 |
| Liu, Z | 1 |
| Lv, D | 1 |
| Wang, J | 1 |
| Xu, ZQ | 1 |
| Liang, XM | 1 |
| Zhang, YF | 1 |
| Zhu, CX | 1 |
| Jiang, XJ | 1 |
| Wang, R | 1 |
4 reviews available for huperzine a and Dementia, Vascular
| Article | Year |
|---|---|
Potential therapeutic targets of huperzine A for Alzheimer's disease and vascular dementia.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Dementia, Vascular; Humans; Sesquiterp | 2008 |
Huperzine A for vascular dementia.
Topics: Alkaloids; Dementia, Vascular; Drugs, Chinese Herbal; Humans; Neuroprotective Agents; Sesquiterpenes | 2009 |
Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment.
Topics: Acetylcholine; Alkaloids; Animals; Anti-Inflammatory Agents; Cholinergic Agents; Cholinesterase Inhi | 2009 |
Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine.
Topics: Alkaloids; Alzheimer Disease; Animals; Apoptosis; Brain; Cholinesterase Inhibitors; Cholinesterases; | 2006 |
1 trial available for huperzine a and Dementia, Vascular
| Article | Year |
|---|---|
Treatment with Huperzine A improves cognition in vascular dementia patients.
Topics: Activities of Daily Living; Aged; Alkaloids; Ascorbic Acid; Cognition; Dementia, Vascular; Double-Bl | 2012 |
1 other study available for huperzine a and Dementia, Vascular
| Article | Year |
|---|---|
A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals with Mild Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Alkaloids; Biosimilar Pharmaceuticals; Cognition Disorders; Curcumin; Demen | 2018 |