Page last updated: 2024-10-21

huperzine a and Cocaine Abuse

huperzine a has been researched along with Cocaine Abuse in 1 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"Huperzine A was safe and well-tolerated and compared with placebo, treatment with huperzine A did not cause significant changes in any cocaine pharmacokinetic parameters (all P>."2.80Safety and Preliminary Efficacy of the Acetylcholinesterase Inhibitor Huperzine A as a Treatment for Cocaine Use Disorder. ( De La Garza, R; Mahoney, JJ; Newton, TF; Thompson-Lake, DG; Verrico, CD, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De La Garza, R1
Verrico, CD1
Newton, TF1
Mahoney, JJ1
Thompson-Lake, DG1

Trials

1 trial available for huperzine a and Cocaine Abuse

ArticleYear
Safety and Preliminary Efficacy of the Acetylcholinesterase Inhibitor Huperzine A as a Treatment for Cocaine Use Disorder.
    The international journal of neuropsychopharmacology, 2015, Sep-12, Volume: 19, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Adult; Alkaloids; Blood Pressure; Cholinesterase

2015