Page last updated: 2024-10-21

huperzine a and Brain Injuries, Traumatic

huperzine a has been researched along with Brain Injuries, Traumatic in 2 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Brain Injuries, Traumatic: A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.

Research Excerpts

ExcerptRelevanceReference
"Huperzine A (HupA) is a naturally occurring acetylcholinesterase inhibitor with newly discovered potent GABA-mediated antiepileptic capacity, which is reliably detected by ppTMS."1.48Alterations in the Timing of Huperzine A Cerebral Pharmacodynamics in the Acute Traumatic Brain Injury Setting. ( Collins, S; Damar, U; Gersner, R; Johnstone, JT; Kapur, K; Rotenberg, A; Schachter, S, 2018)
"Huperzine A (HupA) is a potent acetylcholinesterase inhibitor (AChEI) that has been used treatment of Alzheimer's disease (AD)."1.46Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury. ( Mei, Z; Situ, B; Tan, X; Wang, Y; Zheng, P, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mei, Z1
Zheng, P1
Tan, X1
Wang, Y1
Situ, B1
Damar, U1
Gersner, R1
Johnstone, JT1
Kapur, K1
Collins, S1
Schachter, S1
Rotenberg, A1

Other Studies

2 other studies available for huperzine a and Brain Injuries, Traumatic

ArticleYear
Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.
    Metabolic brain disease, 2017, Volume: 32, Issue:6

    Topics: Alkaloids; Animals; Behavior, Animal; Brain Injuries, Traumatic; Cognition; Encephalitis; Learning;

2017
Alterations in the Timing of Huperzine A Cerebral Pharmacodynamics in the Acute Traumatic Brain Injury Setting.
    Journal of neurotrauma, 2018, 01-15, Volume: 35, Issue:2

    Topics: Alkaloids; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Cholinesterase Inhibitors; Male; Neu

2018