Page last updated: 2024-10-21

huperzine a and Brain Inflammation

huperzine a has been researched along with Brain Inflammation in 3 studies

huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

Research Excerpts

ExcerptRelevanceReference
"Chronic administration of D-galactose (D-gal) results in oxidative stress and chronic inflammatory aging."3.80The neurovascular protective effects of huperzine A on D-galactose-induced inflammatory damage in the rat hippocampus. ( Ao, H; Bao, Z; Gao, Z; Hu, X; Kong, D; Liu, F; Ma, H; Ruan, Q; Yu, Z, 2014)
"Huperzine A (HupA) is a potent acetylcholinesterase inhibitor (AChEI) that has been used treatment of Alzheimer's disease (AD)."1.46Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury. ( Mei, Z; Situ, B; Tan, X; Wang, Y; Zheng, P, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mei, Z1
Zheng, P1
Tan, X1
Wang, Y1
Situ, B1
Ruan, Q1
Hu, X1
Ao, H1
Ma, H1
Gao, Z1
Liu, F1
Kong, D1
Bao, Z1
Yu, Z1
Zhu, SZ1
Huang, WP1
Huang, LQ1
Han, YL1
Han, QP1
Zhu, GF1
Wen, MY1
Deng, YY1
Zeng, HK1

Other Studies

3 other studies available for huperzine a and Brain Inflammation

ArticleYear
Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.
    Metabolic brain disease, 2017, Volume: 32, Issue:6

    Topics: Alkaloids; Animals; Behavior, Animal; Brain Injuries, Traumatic; Cognition; Encephalitis; Learning;

2017
The neurovascular protective effects of huperzine A on D-galactose-induced inflammatory damage in the rat hippocampus.
    Gerontology, 2014, Volume: 60, Issue:5

    Topics: Aging; Alkaloids; Animals; Apoptosis; Blood-Brain Barrier; Cholinesterase Inhibitors; Cytokines; Enc

2014
Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.
    Neuroscience letters, 2016, Sep-19, Volume: 631

    Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Cholin

2016