huperzine a has been researched along with Amyloid Deposits in 3 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huperzine A (HupA) is a potent acetylcholinesterase inhibitor (AChEI) used in the treatment of Alzheimer's disease (AD)." | 1.38 | Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice. ( Tang, XC; Wang, Y; Zhang, HY, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, XT | 1 |
| Qian, ZM | 1 |
| He, X | 1 |
| Gong, Q | 1 |
| Wu, KC | 1 |
| Jiang, LR | 1 |
| Lu, LN | 1 |
| Zhu, ZJ | 1 |
| Zhang, HY | 2 |
| Yung, WH | 1 |
| Ke, Y | 1 |
| Wang, Y | 1 |
| Tang, XC | 1 |
| Sivaprakasam, K | 1 |
1 review available for huperzine a and Amyloid Deposits
| Article | Year |
|---|---|
Towards a unifying hypothesis of Alzheimer's disease: cholinergic system linked to plaques, tangles and neuroinflammation.
Topics: Alkaloids; Alzheimer Disease; Amyloid; Cholinergic Fibers; Cholinesterase Inhibitors; Galantamine; I | 2006 |
2 other studies available for huperzine a and Amyloid Deposits
| Article | Year |
|---|---|
Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease.
Topics: ADAM Proteins; ADAM10 Protein; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precurso | 2014 |
Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice.
Topics: Alkaloids; Amyloid beta-Protein Precursor; Animals; Dendritic Spines; HEK293 Cells; Humans; Mice; Mi | 2012 |