huperzine a has been researched along with Amnesia in 6 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, whether coadministration of huperzine A (HA) and ligustrazine phosphate (LP) could effectively improve the memory deficits in association with ameliorating cholinergic impairment and oxidative stress in the scopolamine-induced amnesia rats was assessed." | 7.76 | Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats. ( Liu, Q; Luo, G; Shi, J; Wang, Y, 2010) |
| "In the present study, whether coadministration of huperzine A (HA) and ligustrazine phosphate (LP) could effectively improve the memory deficits in association with ameliorating cholinergic impairment and oxidative stress in the scopolamine-induced amnesia rats was assessed." | 3.76 | Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats. ( Liu, Q; Luo, G; Shi, J; Wang, Y, 2010) |
| "harmala in learning and memory deficits of scopolamine-induced mice and elucidate the underlying mechanisms involved." | 1.51 | Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice. ( Cheng, X; Deng, G; Ding, W; Guan, H; Ju, Z; Li, S; Liu, W; Ma, C; Rong, X; Wang, C; Wang, Y; Wu, C, 2019) |
| " The improving effects of huperzine A exhibited a bell-shaped dose-response curve." | 1.31 | Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick. ( Gao, Y; Guan, LC; Kuang, PZ; Tang, XC, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, G | 1 |
| Wu, C | 1 |
| Rong, X | 1 |
| Li, S | 1 |
| Ju, Z | 1 |
| Wang, Y | 2 |
| Ma, C | 1 |
| Ding, W | 1 |
| Guan, H | 1 |
| Cheng, X | 1 |
| Liu, W | 1 |
| Wang, C | 1 |
| Patel, PA | 1 |
| Patil, SC | 1 |
| Kalaria, DR | 1 |
| Kalia, YN | 1 |
| Patravale, VB | 1 |
| Shi, J | 1 |
| Liu, Q | 1 |
| Luo, G | 1 |
| Cheng, DH | 1 |
| Ren, H | 1 |
| Tang, XC | 3 |
| Wang, T | 1 |
| Gao, Y | 1 |
| Guan, LC | 1 |
| Kuang, PZ | 1 |
6 other studies available for huperzine a and Amnesia
| Article | Year |
|---|---|
Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice.
Topics: Acetylcholine; Alkaloids; Amnesia; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Choline | 2019 |
Comparative in vitro and in vivo evaluation of lipid based nanocarriers of Huperzine A.
Topics: Administration, Cutaneous; Alkaloids; Amnesia; Animals; Cholinesterase Inhibitors; Drug Carriers; Dr | 2013 |
Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats.
Topics: Acetylcholinesterase; Alkaloids; Amnesia; Animals; Cerebral Cortex; Glutathione Peroxidase; Hippocam | 2010 |
Huperzine A, a novel promising acetylcholinesterase inhibitor.
Topics: Acetylcholinesterase; Alkaloids; Amnesia; Animals; Butyrylcholinesterase; Cerebral Cortex; Cholinerg | 1996 |
Reversal of scopolamine-induced deficits in radial maze performance by (-)-huperzine A: comparison with E2020 and tacrine.
Topics: Alkaloids; Amnesia; Animals; Cholinesterase Inhibitors; Donepezil; Indans; Male; Maze Learning; Musc | 1998 |
Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick.
Topics: Alkaloids; Amnesia; Animals; Avoidance Learning; Chickens; Cholinesterase Inhibitors; GABA Agonists; | 2000 |