huperzine a has been researched along with Amnesia-Memory Loss in 6 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, whether coadministration of huperzine A (HA) and ligustrazine phosphate (LP) could effectively improve the memory deficits in association with ameliorating cholinergic impairment and oxidative stress in the scopolamine-induced amnesia rats was assessed." | 7.76 | Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats. ( Liu, Q; Luo, G; Shi, J; Wang, Y, 2010) |
| "In the present study, whether coadministration of huperzine A (HA) and ligustrazine phosphate (LP) could effectively improve the memory deficits in association with ameliorating cholinergic impairment and oxidative stress in the scopolamine-induced amnesia rats was assessed." | 3.76 | Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats. ( Liu, Q; Luo, G; Shi, J; Wang, Y, 2010) |
| "harmala in learning and memory deficits of scopolamine-induced mice and elucidate the underlying mechanisms involved." | 1.51 | Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice. ( Cheng, X; Deng, G; Ding, W; Guan, H; Ju, Z; Li, S; Liu, W; Ma, C; Rong, X; Wang, C; Wang, Y; Wu, C, 2019) |
| " The improving effects of huperzine A exhibited a bell-shaped dose-response curve." | 1.31 | Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick. ( Gao, Y; Guan, LC; Kuang, PZ; Tang, XC, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, G | 1 |
| Wu, C | 1 |
| Rong, X | 1 |
| Li, S | 1 |
| Ju, Z | 1 |
| Wang, Y | 2 |
| Ma, C | 1 |
| Ding, W | 1 |
| Guan, H | 1 |
| Cheng, X | 1 |
| Liu, W | 1 |
| Wang, C | 1 |
| Patel, PA | 1 |
| Patil, SC | 1 |
| Kalaria, DR | 1 |
| Kalia, YN | 1 |
| Patravale, VB | 1 |
| Shi, J | 1 |
| Liu, Q | 1 |
| Luo, G | 1 |
| Cheng, DH | 1 |
| Ren, H | 1 |
| Tang, XC | 3 |
| Wang, T | 1 |
| Gao, Y | 1 |
| Guan, LC | 1 |
| Kuang, PZ | 1 |
6 other studies available for huperzine a and Amnesia-Memory Loss
| Article | Year |
|---|---|
Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice.
Topics: Acetylcholine; Alkaloids; Amnesia; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Choline | 2019 |
Comparative in vitro and in vivo evaluation of lipid based nanocarriers of Huperzine A.
Topics: Administration, Cutaneous; Alkaloids; Amnesia; Animals; Cholinesterase Inhibitors; Drug Carriers; Dr | 2013 |
Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats.
Topics: Acetylcholinesterase; Alkaloids; Amnesia; Animals; Cerebral Cortex; Glutathione Peroxidase; Hippocam | 2010 |
Huperzine A, a novel promising acetylcholinesterase inhibitor.
Topics: Acetylcholinesterase; Alkaloids; Amnesia; Animals; Butyrylcholinesterase; Cerebral Cortex; Cholinerg | 1996 |
Reversal of scopolamine-induced deficits in radial maze performance by (-)-huperzine A: comparison with E2020 and tacrine.
Topics: Alkaloids; Amnesia; Animals; Cholinesterase Inhibitors; Donepezil; Indans; Male; Maze Learning; Musc | 1998 |
Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick.
Topics: Alkaloids; Amnesia; Animals; Avoidance Learning; Chickens; Cholinesterase Inhibitors; GABA Agonists; | 2000 |