huperzine a has been researched along with Amentia in 7 studies
huperzine A: RN given refers to 5R-(5alpha,9beta,11E)-isomer; structure given in first source
huperzine A : A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An overview of systematic reviews (SRs) was conducted to summarize the findings of SRs and meta-analyses on the effectiveness of Huperzine A (Hup A) in dementia and mild cognitive impairment (MCI)." | 9.12 | The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews. ( Dehghani Ahmadabad, A; Ghassab-Abdollahi, N; Mirghafourvand, M; Mobasseri, K; Nadrian, H, 2021) |
| "Huperzine A is an alkaloid which was first isolated from Huperzia serrata (Thumb) Trev by Zhejiang Academy of Medical Sciences and Shanghai Institute of Materia Medica, Chinese Academy of Sciences." | 6.67 | [Drug evaluation of huperzine A in the treatment of senile memory disorders]. ( Han, YY; Ma, YX; Sang, GW; Tang, XC; Yang, RM; Zhang, CL; Zhang, RW; Zhang, YD, 1991) |
| " An overview of systematic reviews (SRs) was conducted to summarize the findings of SRs and meta-analyses on the effectiveness of Huperzine A (Hup A) in dementia and mild cognitive impairment (MCI)." | 5.12 | The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews. ( Dehghani Ahmadabad, A; Ghassab-Abdollahi, N; Mirghafourvand, M; Mobasseri, K; Nadrian, H, 2021) |
| "Huperzine A is an alkaloid which was first isolated from Huperzia serrata (Thumb) Trev by Zhejiang Academy of Medical Sciences and Shanghai Institute of Materia Medica, Chinese Academy of Sciences." | 2.67 | [Drug evaluation of huperzine A in the treatment of senile memory disorders]. ( Han, YY; Ma, YX; Sang, GW; Tang, XC; Yang, RM; Zhang, CL; Zhang, RW; Zhang, YD, 1991) |
| "Huperzine A (HupA) is a selective inhibitor of acetylcholinesterase (AChE) and has been shown to significantly reduce cognitive impairment in animal models of dementia." | 1.39 | Huperzine A, but not tacrine, stimulates S100B secretion in astrocyte cultures. ( Abib, R; Gonçalves, CA; Guerra, MC; Leite, MC; Lunardi, P; Nardin, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ghassab-Abdollahi, N | 1 |
| Mobasseri, K | 1 |
| Dehghani Ahmadabad, A | 1 |
| Nadrian, H | 1 |
| Mirghafourvand, M | 1 |
| Lunardi, P | 1 |
| Nardin, P | 1 |
| Guerra, MC | 1 |
| Abib, R | 1 |
| Leite, MC | 1 |
| Gonçalves, CA | 1 |
| Lyketsos, CG | 1 |
| Colenda, CC | 1 |
| Beck, C | 1 |
| Blank, K | 1 |
| Doraiswamy, MP | 1 |
| Kalunian, DA | 1 |
| Yaffe, K | 1 |
| Beier, MT | 1 |
| Fink, DM | 1 |
| Bores, GM | 1 |
| Effland, RC | 1 |
| Huger, FP | 1 |
| Kurys, BE | 1 |
| Rush, DK | 1 |
| Selk, DE | 1 |
| Chiu, HF | 1 |
| Zhang, M | 1 |
| Zhang, RW | 1 |
| Tang, XC | 1 |
| Han, YY | 1 |
| Sang, GW | 1 |
| Zhang, YD | 1 |
| Ma, YX | 1 |
| Zhang, CL | 1 |
| Yang, RM | 1 |
3 reviews available for huperzine a and Amentia
| Article | Year |
|---|---|
The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews.
Topics: Activities of Daily Living; Alkaloids; Alzheimer Disease; Cognitive Dysfunction; Dementia; Humans; Q | 2021 |
Harmless herbs? Think again: merits of a complete medication history.
Topics: Aged; Alkaloids; Cholinesterase Inhibitors; Dementia; Evidence-Based Medicine; Galantamine; Geriatri | 2006 |
Dementia research in China.
Topics: Alkaloids; Caregivers; China; Cross-Cultural Comparison; Dementia; Drug Evaluation; Epidemiologic St | 2000 |
1 trial available for huperzine a and Amentia
| Article | Year |
|---|---|
[Drug evaluation of huperzine A in the treatment of senile memory disorders].
Topics: Aged; Alkaloids; Case-Control Studies; Cholinesterase Inhibitors; Dementia; Dementia, Multi-Infarct; | 1991 |
3 other studies available for huperzine a and Amentia
| Article | Year |
|---|---|
Huperzine A, but not tacrine, stimulates S100B secretion in astrocyte cultures.
Topics: Alkaloids; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dementia; | 2013 |
Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease.
Topics: Aged; Alkaloids; Alzheimer Disease; Brain; Caregivers; Cholinesterase Inhibitors; Cognition Disorder | 2006 |
Synthesis and evaluation of 5-amino-5,6,7,8-tetrahydroquinolinones as potential agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Aminoquinolines; Animals; Cholinesterase Inhibit | 1995 |