humulene and Plant-Poisoning

Topics: Animals; Cannabis; Cassia; Cattle; Claviceps; Datura stramonium; Female; Plant Poisoning; Plants, Medicinal; Plants, Toxic; Pregnancy; Ricinus; Senecio; Sheep; Sheep Diseases; Solanaceous Alkaloids; Swine; Swine Diseases; Veratrum

Topics: Abnormalities, Drug-Induced; Alkaloids; Animals; Antithyroid Agents; Arsenic Poisoning; Cadmium Poisoning; Cannabis; Cattle; Cattle Diseases; Female; Food Contamination; Foodborne Diseases; Fusarium; Gossypol; Humans; Lead Poisoning; Manganese Poisoning; Mercury Poisoning; Metals; Mice; Mycotoxins; Neoplasms; Penicillium; Plant Poisoning; Pregnancy; Pyrrolizidine Alkaloids; Rats; Selenium

An increasing number of jurisdictions have legalized recreational cannabis for adult use. The subsequent availability and marketing of recreational cannabis has led to a parallel increase in rates and severity of pediatric cannabis intoxications. We explored predictors of severe outcomes in pediatric patients who presented to the emergency department with cannabis intoxication.. In this prospective cohort study, we collected data on all pediatric patients (<18 years) who presented with cannabis intoxication from August 2017 through June 2020 to participating sites in the Toxicology Investigators Consortium. In cases that involved polysubstance exposure, patients were included if cannabis was a significant contributing agent. The primary outcome was a composite severe outcome endpoint, defined as an intensive care unit admission or in-hospital death. Covariates included relevant sociodemographic and exposure characteristics.. One hundred and thirty-eight pediatric patients (54% males, median age 14.0 years, interquartile range 3.7-16.0) presented to a participating emergency department with cannabis intoxication. Fifty-two patients (38%) were admitted to an intensive care unit, including one patient who died. In the multivariable logistic regression analysis, polysubstance ingestion (adjusted odds ratio = 16.3; 95% confidence interval: 4.6-58.3;. Severe outcomes occurred for different reasons and were largely associated with the patient's age. Young children, all of whom were exposed to edibles, were at higher risk of severe outcomes. Teenagers with severe outcomes were frequently involved in polysubstance exposure, while psychosocial factors may have played a role.

Topics: Adolescent; Adult; Cannabis; Child; Child, Preschool; Emergency Service, Hospital; Female; Foodborne Diseases; Hallucinogens; Hospital Mortality; Humans; Male; Plant Poisoning; Prospective Studies; Psychotropic Drugs; Registries

Topics: Cannabis; Child, Preschool; Humans; Plant Poisoning; Seizures

Topics: Ataxia; Cannabis; Child, Preschool; Diagnosis, Differential; Female; Humans; Plant Poisoning; Seizures; Tremor

A young adult male of about 25 years of age consumed a glass (about 300 ml) of Bhang on the holy occasion of ShivRatri. The deceased died within 24 hours of consuming the Bhang. The deceased had suffered from rheumatic heart disease with multiple valvular involvements. He had also undergone open-heart surgery in the past. Fatality due to Bhang is extremely rare and therefore the case is presented. An attempt is made to review the literature. Bhang is one of the Indian preparations of Indian hemp (Cannabis sativa). It is prepared by the wet grinding of the leaves of the plant. The bolus is then consumed in various ways. Water is used as a vehicle. In the present case a bolus of about 1 to 2 gm was mixed in a glass of water. ShivRatri is a Hindu festival. On this day prayers are offered to Lord Shiva, who is the god of all evils and poisons. Bhang is a special article, which is offered to Lord Shiva on this auspicious day. Then, the devotees consume it as the God. Gujrat is a dry state (possession, consumption, sale, etc. of alcohol, Bhang, opium and other psychotropic substance, etc. is governed by particular laws), but on the holy occasion of ShivRati, for a day, the law is relaxed for the use of Bhang. In most other parts of the country, particularly, in northern India, it is a common practice to consume various preparations of Indian hemp like Bhang, Charas, Ganja, sweetmeat, etc. The bolus mentioned above is probably the minimum single dose.

Topics: Adult; Cannabinoids; Cannabis; Death, Sudden, Cardiac; Fatal Outcome; Hinduism; Humans; India; Male; Mitral Valve; Mitral Valve Stenosis; Plant Poisoning; Religion and Psychology; Rheumatic Heart Disease; Risk Factors

Topics: Animals; Cannabis; Cattle; Cattle Diseases; Plant Poisoning

Topics: Cannabinoids; Cannabis; Female; Humans; Infant; Plant Poisoning

Topics: Cannabis; Child, Preschool; Humans; Infant; Male; Plant Poisoning

Topics: Animals; Cannabis; Dog Diseases; Dogs; Plant Poisoning

Topics: Animals; Cannabis; Dog Diseases; Dogs; Male; Plant Poisoning

Topics: Animals; Cannabis; Dog Diseases; Dogs; Female; Plant Poisoning

Topics: Animals; Cannabis; Dog Diseases; Dogs; Male; Plant Poisoning

Topics: Blood Pressure; Cannabis; Datura stramonium; Hallucinations; Humans; Male; Middle Aged; Plant Poisoning; Plants, Medicinal; Plants, Toxic; Pulse; Pupil; Seeds; Singapore