humulene and Peritonitis

The body packing represents an illegal drug trafficking practice across the borders of certain countries. It has experienced enormous growth in recent years. The medical literature is rich in publications interested in body packaging of cocaine or heroin with sometimes lethal consequences. However, reported cases of cannabis body packing appear to be rare, sometimes underestimated, despite the notoriety of cannabis in the illegal drug market and its wide consumption around the world. We report in this work a forensic case of a cannabis body packer deceased due toa stercoral peritonitis secondary to a double perforation of thesigmoid and rectal colon.

Topics: Body Packing; Cannabis; Colon, Sigmoid; Drug Trafficking; Foreign Bodies; Humans; Intestinal Perforation; Male; Middle Aged; Peritonitis; Rectum

Body weight, food and water intake, and feces weight of 20 albino rats were recorded daily for 70 days. On days 11 to 40, 12 rats received behaviorally effective doses of Delta-9-tetrahydrocannabinol, either orally or intraperitoneally. These rats ate significantly less than placebo-dosed controls during the treatment period, and gained significantly less weight. Food intake recovered in the 30-day posttreatment period, but the former drug group still weighed less than the controls on day 70. In addition, all rats who had received intraperitoneal injections of Delta-9-tetrahydrocannabinol showed evidence of chronic diffuse nonsuppurative peritonitis.

Topics: Animals; Appetite; Body Weight; Cannabis; Depression, Chemical; Dronabinol; Growth; Injections, Intraperitoneal; Male; Peritonitis; Placebos; Rats; Time Factors