humulene and Infertility

Reducing exposure to tobacco and marijuana during preconception and early pregnancy is a critical area of intervention for obstetricians, gynecologists, and other reproductive health care professionals. Beyond the deleterious personal health effects, both substances have been extensively associated with short-term and long-term detrimental effects to gametogenesis, fecundity, as well as tissue level effects in the reproductive tracts. When tobacco and marijuana do not impair the ability to achieve pregnancy, an increasing body of literature suggests either may be associated with increased risk of early pregnancy loss and reproductive wastage. In this review, we will discuss what is known about how tobacco and marijuana affect the male and female reproductive systems and highlight how these consequences may impair attempts at successful conception and pregnancy continuation beyond the first trimester.

Topics: Cannabis; Female; Fertility; Gynecology; Humans; Infertility; Male; Nicotiana; Pregnancy

There are numerous toxic factors in environment that can influence fecundity, without forgetting behaviour toxins as medicaments, tobacco, alcohol, cannabis. These mailmen will have an influence in the course of the Medical care in Procreation, some of them diminish the chances of success; it is necessary to spot risk factors and to act as a precautionary measure to ameliorate the fecundity of the couple and results in AMP.

Topics: Cannabis; Environmental Pollutants; Ethanol; Female; Humans; Infertility; Male; Reproductive Techniques, Assisted; Risk Factors; Smoking

Primary infertility may result from the use of various drugs. This phenomenon may be the result of an effect on the hypothalamic-pituitary-gonadal axis or a direct toxic effect on the gonads. Some of the drugs considered in this article demonstrate sex-related differences in their ability to cause infertility; there also may be age-related differences. The drugs described in this review, in regard to their association with the development of infertility, include various individual antineoplastic agents (cyclophosphamide, chlorambucil, busulphan, and methotrexate) and combinations of these chemotherapeutic drugs, glucocorticosteroids, hormonal steroids (diethylstilbestrol, medroxyprogesterone acetate, estrogen, and the constituents of oral contraceptives), antibiotics (sulfasalazine and co-trimoxazole), thyroid supplements, spironolactone, cimetidine, colchicine, marihuana, opiates, and neuroleptic agents.. Primary infertility may result from the use of various drugs. This phenomenon may be the result of an effect on the hypothalamic-pituitary-gonadal axis or a direct toxic effect on the gonads. Some of the drugs considered in this article demonstrate sex-related differences in their ability to cause infertility; there also may be age-related differences. The drugs described in this review, with regard to their association with the development of infertility, include various individual antineoplastic agents (cyclophosphamide, chlorambucil, busulphan, and methotrexate) and combinations of these chemotherapeutic drugs, glucocorticosteroids, hormonal steroids (diethylstilbestrol, medroxyprogesterone acetate, estrogen, and the constituents of oral contraceptives), antibiotics (sulfasalazine and cotrimoxazole), thyroid supplements, spironolactone, cimetidine, colchicine, marijuana, opiates, and neuroleptic agents.

Topics: Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Antipsychotic Agents; Cannabis; Child; Child, Preschool; Cimetidine; Colchicine; Contraceptives, Oral; Female; Humans; Infertility; Male; Middle Aged; Narcotics; Spironolactone; Steroids; Thyroid Hormones