humulene and Heart-Diseases

humulene has been researched along with Heart-Diseases* in 7 studies

Reviews

1 review(s) available for humulene and Heart-Diseases

ArticleYear
The Protective Mechanism of Cannabidiol in Cardiac Injury: A Systematic Review of Non-Clinical Studies.
    Current pharmaceutical design, 2019, Volume: 25, Issue:22

    Cardiac disease is accounted as the leading cause of worldwide morbidity and mortality. The disease is characterized by the overproduction of reactive oxygen and/or nitrogen species (ROS/RNS), and induction of oxidative stress. Cannabidiol (CBD) is a non-psychoactive ingredient of marijuana that has been reported to be safe and well tolerated in patients. Due to its pleiotropic effect, CBD has been shown to exert cytoprotective effects. This study intended to clarify the mechanisms and the potential role of CBD regarding cardiac injuries treatment.. A systematic literature search was conducted, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, in the electronic databases including PubMed, Web of Science, Scopus, and Embase up to June 2019 using predefined search terms in the titles and abstracts. Accordingly, a set of pre-specified inclusion and exclusion criteria were considered and 8 articles were ultimately included in this study.. Our findings demonstrate that CBD has multi-functional protective assets to improve cardiac injuries; preliminary through scavenging of free radicals, and reduction of oxidative stress, apoptosis, and inflammation.. CBD can protect against cardiac injuries, mainly through its antioxidative and antiapoptotic effects on the basis of non-clinical studies. The cardioprotective effects of the CBD need to be further studied in welldesigned clinical trials.

    Topics: Apoptosis; Cannabidiol; Cannabis; Cardiotonic Agents; Free Radical Scavengers; Heart Diseases; Humans; Oxidative Stress; Reactive Oxygen Species

2019

Other Studies

6 other study(ies) available for humulene and Heart-Diseases

ArticleYear
Pediatric cannabis use and cardiac complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021, 11-15, Volume: 193, Issue:45

    Topics: Analgesics; Cannabis; Child; Hallucinogens; Heart Diseases; Humans

2021
Editorial commentary: Cardiovascular complications of cannabis use.
    Trends in cardiovascular medicine, 2019, Volume: 29, Issue:7

    Topics: Cannabis; Cardiovascular System; Heart Diseases; Humans

2019
Cannabis and Heart Disease: Forward Into the Great Unknown?
    Journal of the American College of Cardiology, 2018, 06-05, Volume: 71, Issue:22

    Topics: Cannabis; Cocaine; Heart Diseases; Humans; Marijuana Use; Myocardial Infarction; Young Adult

2018
A little "dab" will do ya' in: a case report of neuro-and cardiotoxicity following use of cannabis concentrates.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:9

    The use of marijuana and cannabis concentrates is increasing, especially following decriminalization in several states. Psychosis and cardiotoxicity have been reported following cannabis use; however, myocardial injury from "dabbing" has not yet been reported. We report a case of hyperthermia, tachycardia, hypertension, severe agitation, neuro-, and cardiotoxicity following the use of "dabs" where there is concomitant confirmatory biological and sample testing.. A 17-year-old athletic man developed agitation requiring sedation and intubation for safety, with peak systolic blood pressures in the 190s and hyperthermia (to 102 °F). He developed elevated serum troponins with persistent tachycardia despite sedation and no clear non-intoxicant etiology. It was discovered that the patient had recently been "dabbing"; an exhaustive search of his home found a sample of the "dabs" which was analyzed along with a comprehensive urine drug screen by tandem liquid mass spectroscopy (t-LCMS) for confirmation.. Tetrahydrocannabinol (THC) has been increasingly associated with agitation and cardiotoxicity, while cannabidiol (CBD) has been associated with neuroprotective, inhibitory states. We propose that increasing concentrations of THC as well as THC:CBD ratios seen in cannabis concentrates such as "dabs" may cause agitation and end-organ damage through sympathomimetic and serotonergic pathways.

    Topics: Administration, Inhalation; Adolescent; Cannabis; Cardiotoxicity; Heart Diseases; Humans; Male; Marijuana Abuse; Neurotoxicity Syndromes; Plant Extracts; Substance Abuse Detection; Tandem Mass Spectrometry; Urinalysis

2017
Can your heart handle the spice: A case of acute myocardial infarction and left ventricular apical thrombus.
    International journal of cardiology, 2016, Jul-15, Volume: 215

    Topics: Cannabinoids; Cannabis; Heart Diseases; Heart Ventricles; Humans; Illicit Drugs; Indoles; Male; Myocardial Infarction; Naphthalenes; Thrombosis; Young Adult

2016
[Addictions].
    Revue medicale suisse, 2006, Jan-04, Volume: 2, Issue:47

    This year reviews on the addictions emphasizes five aspects, on a bio-psycho-social perspective: (1) The relationship between methadone and cardiotoxicity. (2) The introduction of Eye Movement Desensibilization and Reprocessing (EMDR). (3) The apparition of a possible specific pharmacotherapy for excessive gambling. (4) A better knowledge of the relationship between cannabis and psychoses. (5) Resistance to treatment in the doctor-patient relationship.

    Topics: Cannabis; Eye Movements; Gambling; Heart Diseases; Methadone; Narcotics; Physician-Patient Relations; Psychotic Disorders; Substance-Related Disorders

2006
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