hu-308 has been researched along with Amyotrophic-Lateral-Sclerosis* in 1 studies
1 other study(ies) available for hu-308 and Amyotrophic-Lateral-Sclerosis
Article | Year |
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Targeting glial cannabinoid CB
Cannabinoid CB. We treated TDP-43 (A315T) transgenic mice with the non-selective agonist WIN55,212-2, alone or combined with selective CB. WIN55,212-2 had modest beneficial effects in the rotarod test, Nissl staining of motor neurons, and GFAP and Iba-1 immunostainings in the spinal cord, which were mediated in part by CB. Our study shows an important role for glial CB Topics: Amyotrophic Lateral Sclerosis; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; DNA-Binding Proteins; Mice, Transgenic; Microglia; Morpholines; Motor Activity; Motor Neurons; Naphthalenes; Receptor, Cannabinoid, CB2; Rotarod Performance Test | 2019 |