hu-210 has been researched along with Disease-Models--Animal* in 1 studies
1 other study(ies) available for hu-210 and Disease-Models--Animal
Article | Year |
---|---|
Pyridine-3-carboxamides as novel CB(2) agonists for analgesia.
We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB(2) receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a which demonstrated efficacy in an in vivo model of inflammatory pain. Topics: Amides; Analgesia; Analgesics; Animals; Disease Models, Animal; Drug Discovery; Inflammation; Pain; Pyridines; Receptor, Cannabinoid, CB2; Structure-Activity Relationship | 2009 |