Page last updated: 2024-08-25

honokiol and Lung Neoplasms

honokiol has been researched along with Lung Neoplasms in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (15.63)29.6817
2010's17 (53.13)24.3611
2020's10 (31.25)2.80

Authors

AuthorsStudies
Amin, S; Lin, JM; Prakasha Gowda, AS; Sharma, AK1
Chen, K; Chen, L; Fu, S; Li, D; Liu, Z; Peng, A; Tang, H; Tang, M; Wan, L; Xue, L; Ye, H; Zhang, Y1
Jiang, D; Liu, J; Liu, X; Pan, Y; Qiu, Y; Shi, Y; Wan, H; Wang, P; Ying, K; Zhu, Y1
Du, K; Jia, Y; Li, Y; Liu, Y; Luo, Y; Wang, B; Wang, Z; Yang, J; Yang, S; Zhu, B1
Chen, T; Cheng, X; Fan, L; Huang, Y; Qiao, Y; Shen, X; Wang, F; Wei, M; Yu, D1
Mu, HJ; Sun, YL; Wang, J; Wang, Y; Yuan, B1
Li, M; Mei, M; Tang, L; Xue, N; Zhou, H1
Cai, N; Jin, X; Yang, Q; Zhang, Z1
Arbiser, J; Fan, S; Owonikoko, TK; Qian, G; Ramalingam, SS; Sun, SY; Zang, H1
Chen, W; Jin, X; Li, F; Li, H; Li, Q; Liu, B1
Chen, CG; Jiang, Q; Li, J; Li, XQ; Long, WG; Ren, J; Su, JY; Wang, Y; Zhu, YM1
Chen, Y; Hu, X; Li, J; Li, Y; Qu, J; Wang, D; Wang, Z; Xia, M; Yuan, R; Zhang, H; Zhang, Y1
Krahn, MP; Kullmann, L1
Cheng, L; Fu, M; Ju, RJ; Li, XT; Liu, JJ; Wang, X; Xiao, Y; Xie, HJ1
Bao, Z; Cen, M; Cui, L; Fang, L; Lu, G; Yang, G; Yao, Y; Zhou, J1
Feng, J; Gao, W; Xu, S; Zhao, G; Zhu, J1
Deng, S; Ma, L; Yang, L; Zhang, C1
Ding, Z; Fu, R; Shen, W; Wan, Y; Zhang, J; Zhang, Y; Zhen, Y1
Chen, SZ; Li, Y; Shang, Y; Wang, WD1
Katiyar, SK; Singh, T1
Kalyanaraman, B; Komas, SM; Liu, Q; Lubet, RA; Pan, J; Wang, Y; You, M; Zhang, Q1
Anandharaj, A; Hong, KH; Kassie, F; Kim, JH; Kirtane, AR; Panyam, J; Song, JM; Upadhyaya, P1
Chen, SZ; Lv, XQ; Qiao, XR; Su, L1
Ahmad, A; Arora, S; Averett, C; Bhardwaj, A; Carter, JE; Khan, MA; Khushman, M; Singh, AP; Singh, S; Srivastava, SK1
Lee, Y; Pan, J; Wan, TC; Wang, Y; Xiong, D; You, M; Zhang, Q1
Acker, TM; Arbiser, JL; Chen, S; Khuri, FR; Lefkove, B; Raja, SM; Sun, SY; Yue, P1
Chen, LJ; Fan, LY; Guo, WH; Hou, WL; Jiang, QQ; Wei, YQ; Yang, GL1
Chen, L; Fu, S; Gong, C; Gou, M; Men, K; Qian, Z; Qiu, L; Shi, S; Wei, X; Zeng, S; Zheng, X1
Chen, LJ; Chen, PL; Chen, X; Hou, WL; Hu, J; Liu, L; Tang, MH; Wang, XH; Wei, YQ; Yang, G; Zhang, F; Zhao, X1
Gong, C; Guo, G; Luo, F; Mao, Y; Qian, Z; Wang, X; Wang, Y; Wei, X1
Arbiser, J; Arlt, MJ; Banke, IJ; Born, W; Fuchs, B; Langsam, B; Muff, R; Steinmann, P; Walters, DK; Ziegler, U1
Hsieh, MT; Hsu, SL; Tsai, TH; Yang, SE1

Reviews

2 review(s) available for honokiol and Lung Neoplasms

ArticleYear
Use of honokiol in lung cancer therapy: a mini review of its pharmacological mechanism.
    Journal of Asian natural products research, 2023, Volume: 25, Issue:11

    Topics: Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Lignans; Lung Neoplasms; Signal Transduction

2023
Controlling the master-upstream regulation of the tumor suppressor LKB1.
    Oncogene, 2018, Volume: 37, Issue:23

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Biphenyl Compounds; Calcium-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lignans; Lung Neoplasms; Lysosomes; Mutation; Peutz-Jeghers Syndrome; Phosphorylation; Protein Serine-Threonine Kinases; Sumoylation; Ubiquitination

2018

Other Studies

30 other study(ies) available for honokiol and Lung Neoplasms

ArticleYear
In vitro growth inhibition of human cancer cells by novel honokiol analogs.
    Bioorganic & medicinal chemistry, 2012, May-15, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Lignans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship

2012
Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Lung Neoplasms; Magnolia; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays

2018
A multidimensional biosensor system to guide LUAD individualized treatment.
    Journal of materials chemistry. B, 2021, 10-06, Volume: 9, Issue:38

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biosensing Techniques; Biphenyl Compounds; Cell Culture Techniques; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lignans; Lung Neoplasms; Male; Mice; Mice, Nude; Piperidines; Precision Medicine; Quinazolines; Tumor Cells, Cultured

2021
PCAT19 Regulates the Proliferation and Apoptosis of Lung Cancer Cells by Inhibiting miR-25-3p via Targeting the MAP2K4 Signal Axis.
    Disease markers, 2022, Volume: 2022

    Topics: Animals; Anisomycin; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lignans; Lung Neoplasms; MAP Kinase Kinase 4; Mice; Mice, Nude; MicroRNAs; RNA, Long Noncoding

2022
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway.
    Chemico-biological interactions, 2023, Jan-25, Volume: 370

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Human Umbilical Vein Endothelial Cells; Humans; Interleukins; Lung Neoplasms; Neovascularization, Pathologic; NF-kappa B; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2023
Honokiol prevents lung metastasis of triple-negative breast cancer by regulating polarization and recruitment of macrophages.
    European journal of pharmacology, 2023, Nov-15, Volume: 959

    Topics: Animals; Cell Line, Tumor; Humans; Lung Neoplasms; Macrophages; Mice; Signal Transduction; Triple Negative Breast Neoplasms; Tumor Microenvironment

2023
A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment.
    Nanomedicine (London, England), 2020, Volume: 15, Issue:1

    Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Biphenyl Compounds; Cell Proliferation; Cisplatin; Ginsenosides; Humans; Lignans; Liposomes; Lung Neoplasms; Mice; Neoplasm Invasiveness; Pentacyclic Triterpenes; Sesquiterpenes; Triterpenes; Xenograft Model Antitumor Assays

2020
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
    Molecular oncology, 2020, Volume: 14, Issue:4

    Topics: Acrylamides; Aniline Compounds; Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Humans; Lignans; Lung Neoplasms; Mice, Nude; Mutation; Protein Kinase Inhibitors

2020
Radiosensitization of NSCLC cells to X-rays and carbon ions by the CHK1/CHK2 inhibitor AZD7762, Honokiol and Tunicamycin.
    Radiation and environmental biophysics, 2020, Volume: 59, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Carbon; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Breaks, Double-Stranded; G2 Phase Cell Cycle Checkpoints; Humans; Ions; Lignans; Linear Energy Transfer; Lung Neoplasms; Protein Kinase Inhibitors; Radiation Tolerance; Radiation-Sensitizing Agents; Thiophenes; Tunicamycin; Urea; X-Rays

2020
Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:1

    Topics: Animals; Apoptosis; Biphenyl Compounds; Calcium; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Lignans; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Paclitaxel; Proteasome Endopeptidase Complex; Ubiquitin-Activating Enzymes; Vacuoles

2021
Augment the efficacy of eradicating metastatic lesions and tumor proliferation in breast cancer by honokiol-loaded pH-sensitive targeted lipid nanoparticles.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 207

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen-Ion Concentration; Lignans; Lipids; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles

2021
Functional paclitaxel plus honokiol micelles destroying tumour metastasis in treatment of non-small-cell lung cancer.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Cell Survival; Dequalinium; Drug Interactions; Drug Liberation; Humans; Lignans; Lung Neoplasms; Mice; Micelles; Neoplasm Metastasis; Paclitaxel; Temperature; Xenograft Model Antitumor Assays

2018
Honokiol induces apoptosis of lung squamous cell carcinoma by targeting FGF2-FGFR1 autocrine loop.
    Cancer medicine, 2018, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Fibroblast Growth Factor 2; Humans; Lignans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Receptor, Fibroblast Growth Factor, Type 1

2018
Honokiol induces endoplasmic reticulum stress-mediated apoptosis in human lung cancer cells.
    Life sciences, 2019, Mar-15, Volume: 221

    Topics: A549 Cells; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Movement; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Lignans; Lung Neoplasms; RNA, Small Interfering; Signal Transduction; Transcription Factor CHOP

2019
Formylated honokiol analogs showed antitumor activity against lung carcinoma.
    Anti-cancer drugs, 2019, Volume: 30, Issue:8

    Topics: Adenocarcinoma of Lung; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Lewis Lung; Cell Proliferation; Female; Formates; Humans; Lignans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Cytological effects of honokiol treatment and its potential mechanism of action in non-small cell lung cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 117

    Topics: A549 Cells; Apoptosis; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lignans; Lung Neoplasms; MicroRNAs; Principal Component Analysis; RNA, Messenger

2019
Honokiol inhibits breast cancer cell metastasis by blocking EMT through modulation of Snail/Slug protein translation.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Humans; Lignans; Lung Neoplasms; Mice, Inbred BALB C; Snail Family Transcription Factors

2019
Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE₂-mediated activation of β-catenin signaling.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: beta Catenin; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drugs, Chinese Herbal; Gene Knockdown Techniques; Humans; Lignans; Lung Neoplasms; Neoplasm Invasiveness; RNA Interference; Signal Transduction; Sulfonamides; Transcription Factor RelA

2013
Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:11

    Topics: Adenosine Triphosphate; Animals; Anticarcinogenic Agents; Apoptosis; Biphenyl Compounds; Bronchi; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; Lignans; Lung Neoplasms; Mice; Mitochondria; Neoplasm Transplantation; Oxidation-Reduction; Reactive Oxygen Species

2014
Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors.
    Oncotarget, 2016, Sep-06, Volume: 7, Issue:36

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Assay; Biphenyl Compounds; Bronchi; Carcinogenesis; Cell Cycle; Cell Proliferation; Cell Survival; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Female; Lignans; Lung Neoplasms; Magnolia; Mice; Molecular Docking Simulation; Nitrosamines; Plant Extracts; RNA, Small Interfering

2016
Honokiol inhibits EMT-mediated motility and migration of human non-small cell lung cancer cells in vitro by targeting c-FLIP.
    Acta pharmacologica Sinica, 2016, Volume: 37, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Lignans; Lung Neoplasms

2016
Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.
    Carcinogenesis, 2016, 11-01, Volume: 37, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Communication; Cell Line, Tumor; Down-Regulation; Female; Gene Expression; Hedgehog Proteins; Humans; Lignans; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Pancreatic Neoplasms; Receptors, CXCR4; Tumor Microenvironment; Xenograft Model Antitumor Assays

2016
Honokiol Decreases Lung Cancer Metastasis through Inhibition of the STAT3 Signaling Pathway.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Lignans; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred NOD; Mice, SCID; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2017
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:7

    Topics: Apoptosis; Biphenyl Compounds; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Lignans; Lung Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Ubiquitin

2008
Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model.
    BMC cancer, 2008, Aug-16, Volume: 8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cisplatin; Humans; In Situ Nick-End Labeling; Lignans; Liposomes; Lung Neoplasms; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Plant Extracts; Platelet Endothelial Cell Adhesion Molecule-1

2008
Self-assembled honokiol-loaded micelles based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) copolymer.
    International journal of pharmaceutics, 2009, Mar-18, Volume: 369, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Lasers; Lignans; Lung Neoplasms; Micelles; Microscopy, Atomic Force; Particle Size; Polyesters; Polyethylene Glycols; Temperature

2009
Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity.
    Experimental & molecular medicine, 2008, Dec-31, Volume: 40, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biphenyl Compounds; Carcinoma, Lewis Lung; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; Humans; Lignans; Liposomes; Lung Neoplasms; Magnolia; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Radiation Tolerance; Transplantation, Heterologous

2008
Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization.
    Nanotechnology, 2010, May-28, Volume: 21, Issue:21

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drug Stability; Drugs, Chinese Herbal; Humans; Lignans; Lung Neoplasms; Mice; Micelles; Microscopy, Electron, Transmission; Particle Size; Polyesters; Polyethylene Glycols; Solubility; Sonication; X-Ray Diffraction

2010
Antimetastatic activity of honokiol in osteosarcoma.
    Cancer, 2012, Apr-15, Volume: 118, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Bone Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Lignans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred C3H; Osteosarcoma

2012
Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells.
    Biochemical pharmacology, 2002, May-01, Volume: 63, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Biphenyl Compounds; Caspases; Cytochrome c Group; Enzyme Activation; Humans; Lignans; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2002