Page last updated: 2024-08-25

honokiol and Disease Models, Animal

honokiol has been researched along with Disease Models, Animal in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (13.95)29.6817
2010's29 (67.44)24.3611
2020's8 (18.60)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Singh, L; Singh, S1
Jin, J; Kang, KP; Kim, W; Park, SK; Park, W; Quan, Y1
Gao, H; Huan, Y; Lin, J; Peng, X; Zhan, L; Zhang, Y; Zhao, G; Zhu, Y1
Cheng, P; Liu, Y; Wu, AH1
Fang, Z; Lu, P; Sheng, J; Wang, Y; Wei, X1
Chang, HS; Duan, XH; Hu, KL; Li, LN; Li, Y; Liu, M; Yu, X; Zhang, B1
Huang, W; Li, Y; Liu, H; Mai, G1
Arbiser, J; Fang, YH; Gupta, MP; Kanwal, A; Pillai, VB; Samant, S; Sharp, WW1
Bu, P; Huang, C; Li, J; Li, N; Liu, H; Shan, X; Yan, X; Yang, Y; Zhang, C; Zhang, J; Zhang, P; Zhang, Y1
Li, Y; Ni, C; Song, G; Wang, M1
Arbiser, JL; Burd, EM; Chen, CW; Coopersmith, CM; Farris, AB; Ford, ML; Klingensmith, NJ; Liang, Z1
Hur, HJ; Hwang, JT; Jeon, EJ; Jeong, YH; Lee, AS; Lee, KW; Park, SJ; Sung, MJ1
Hou, T; Jia, J; Li, H; Tian, Y; Wang, W; Wang, X; Wei, Y; Wu, Q; Xu, L1
Chan, MH; Chang, PC; Chen, C; Chen, HH1
Hong, T; Hui, Z; Liang, XZ; Lixing, Y; Min, H; Yuejian, L1
Han, F; Lu, X; Xu, J1
Xiang, L; Zhang, T1
Çetin, A; Deveci, E1
Chen, A; He, S; Ling, Y; Liu, H; Song, X; Tan, Z; Wang, S; Wang, X; Yan, J; Yan, Y1
Guo, N; Hao, K; Liu, C; Liu, Z; Wang, J; Yan, Z1
Chang, HS; Hu, KL; Li, LN; Lu, Y; Wang, PP; Yu, X; Zhang, B1
Gao, CY; Guo, S; Han, JY; Wei, N; Xu, JJ; Xu, PS; Xue, R1
Fang, M; Li, L; Li, N; Lin, H; Wang, J; Xie, H; Yang, N1
Bu, Q; Liu, X; Liu, Y; Wang, Y; Zhu, Y1
Huo, G; Liao, Z; Shi, Q; Sun, X; Tang, X; Tang, Z; Wang, H; Xie, Y; Zhi, X1
Cho, IJ; Jang, EJ; Jegal, KH; Jung, JY; Kang, SH; Kim, SC; Kim, YW; Ku, SK; Lee, JH; Lee, JR; Moon, SY; Park, SJ; Zhao, RJ1
Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K1
Agacayak, E; Alabalik, U; Findik, FM; Gul, T; Icen, MS; Tunc, SY; Yuksel, H1
Chen, L; Cheng, X; Li, S; Pei, H; Qiu, N; Wang, W; Wang, X; Wen, J; Xie, C1
Fu, X; Gao, X; Guo, Y; Hu, X; Huo, B; Li, W; Liu, Y; Sun, J; Wang, Y1
Lee, Y; Pan, J; Wang, Y; You, M1
Gao, X; Guo, G; Hu, X; Liu, X; Liu, Y; Mao, Q; Wang, X; Xu, G; You, C; Yu, T; Zhou, L1
Chung, YS; Kim, YC; Lee, BH; Shin, YK; Yin, HQ1
Chilampalli, S; Dwivedi, C; Fahmy, H; Hildreth, MB; Kaushik, RS; Zeman, D; Zhang, X1
Chang-Mu, C; Jen-Kun, L; Shing-Hwa, L; Shoei-Yn, LS1
Bishop, GA; Businga, TR; Kline, JN; Munroe, ME1
Chen, BL; Liu, SH; Weng, TI; Wu, HY1
Chan, MH; Chen, HH; Ko, CH; Lin, YR2
Chiang, CK; Hung, KY; Liu, SH; Sheu, ML; Wu, KD1
Kong, LD; Li, JM; Li, YC; Pan, Y; Wang, CP; Wang, X; Xu, Q; Yi, LT1
Chen, L; Huang, C; Li, Z; Liu, Y; Pan, X; Wei, Y; Yin, R; Zhao, X1

Reviews

1 review(s) available for honokiol and Disease Models, Animal

ArticleYear
Honokiol targets mitochondria to halt cancer progression and metastasis.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Line, Tumor; Disease Models, Animal; ErbB Receptors; Humans; Lignans; Magnolia; Mitochondria; Neoplasms; Plant Extracts; Polyphenols

2016

Other Studies

42 other study(ies) available for honokiol and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Neuroprotective potential of Honokiol in ICV-STZ induced neuroinflammation, Aβ
    Neuroscience letters, 2023, 03-16, Volume: 799

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Maze Learning; Models, Theoretical; Neuroinflammatory Diseases; Neuroprotective Agents; Neurotransmitter Agents; NF-kappa B; Oxidative Stress; Peptide Fragments; Rats; Rats, Wistar; Streptozocin

2023
Sirtuin 3 Activation by Honokiol Decreases Unilateral Ureteral Obstruction-Induced Renal Inflammation and Fibrosis via Regulation of Mitochondrial Dynamics and the Renal NF-κBTGF-β1/Smad Signaling Pathway.
    International journal of molecular sciences, 2020, Jan-08, Volume: 21, Issue:2

    Topics: Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Fibrosis; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Kidney Diseases; Lignans; Mice; Mitochondrial Dynamics; NF-kappa B; Signal Transduction; Sirtuin 3; Smad Proteins; Transforming Growth Factor beta1

2020
Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis.
    Investigative ophthalmology & visual science, 2020, 04-09, Volume: 61, Issue:4

    Topics: Animals; Anti-Infective Agents; Aspergillosis; Aspergillus fumigatus; Biphenyl Compounds; Blotting, Western; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Infections, Fungal; Female; Keratitis; Lignans; Mice; Mice, Inbred C57BL; Random Allocation; Real-Time Polymerase Chain Reaction; Toll-Like Receptor 2; Treatment Outcome

2020
Honokiol inhibits carotid artery atherosclerotic plaque formation by suppressing inflammation and oxidative stress.
    Aging, 2020, 05-04, Volume: 12, Issue:9

    Topics: Animals; Atherosclerosis; Biphenyl Compounds; Carotid Arteries; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Inflammation; Lignans; Male; Mice; Oxidative Stress; Plaque, Atherosclerotic; Signal Transduction

2020
Honokiol-mesoporous Silica Nanoparticles Inhibit Vascular Restenosis via the Suppression of TGF-β Signaling Pathway.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Biphenyl Compounds; Carotid Artery Injuries; Cell Line; Cell Proliferation; Coronary Restenosis; Disease Models, Animal; Drug Delivery Systems; Humans; Lignans; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nanoparticles; Percutaneous Coronary Intervention; Poloxamer; Rats, Sprague-Dawley; Silicon Dioxide

2020
Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression.
    Journal of integrative neuroscience, 2020, Sep-30, Volume: 19, Issue:3

    Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Corticosterone; Depression; Disease Models, Animal; Hippocampus; Lignans; Male; Mineralocorticoids; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger

2020
The Effects of Rhein and Honokiol on Metabolic Profiles in a Mouse Model of Acute Pancreatitis.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, Oct-23, Volume: 26

    Topics: Amylases; Animals; Anthraquinones; Biphenyl Compounds; Disease Models, Animal; Enzyme Inhibitors; Lignans; Male; Metabolome; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis

2020
Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Animals; Biphenyl Compounds; Cardiomyopathies; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Doxorubicin; Lignans; Mice; Mitochondria, Heart; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Sirtuin 3; Up-Regulation

2017
SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension.
    Oncotarget, 2017, Jun-13, Volume: 8, Issue:24

    Topics: Acetylation; Angiotensin II; Animals; Biphenyl Compounds; Disease Models, Animal; Fibrosis; Gene Expression; Gene Expression Regulation; Hypertension, Renal; Kidney; Kruppel-Like Transcription Factors; Lignans; Mice; Mice, Knockout; Models, Biological; Nephritis; Nuclear Proteins; Podocytes; Protein Binding; Signal Transduction; Sirtuin 3

2017
Honokiol Attenuates Oligomeric Amyloid β1-42-Induced Alzheimer's Disease in Mice Through Attenuating Mitochondrial Apoptosis and Inhibiting the Nuclear Factor Kappa-B Signaling Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biphenyl Compounds; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hippocampus; Lignans; Male; Maze Learning; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; NF-kappa B; Peptide Fragments; Reactive Oxygen Species; Signal Transduction

2017
Honokiol Increases CD4+ T Cell Activation and Decreases TNF but Fails to Improve Survival Following Sepsis.
    Shock (Augusta, Ga.), 2018, Volume: 50, Issue:2

    Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Biphenyl Compounds; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Inflammation; Lectins, C-Type; Lignans; Lymphocyte Activation; Lymphocyte Count; Male; Mice; Random Allocation; Sepsis; Tumor Necrosis Factor-alpha

2018
Honokiol Improves Liver Steatosis in Ovariectomized Mice.
    Molecules (Basel, Switzerland), 2018, Jan-17, Volume: 23, Issue:1

    Topics: Adiposity; Animals; Biomarkers; Biphenyl Compounds; Body Weight; Cytokines; Disease Models, Animal; Fatty Liver; Gene Expression Profiling; Inflammation Mediators; Lignans; Lipid Metabolism; Liver; Mice; Non-alcoholic Fatty Liver Disease; Organ Size; Ovariectomy

2018
Honokiol Alleviates Cognitive Deficits of Alzheimer's Disease (PS1V97L) Transgenic Mice by Activating Mitochondrial SIRT3.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 64, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Biphenyl Compounds; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Female; Hippocampus; Lignans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neurons; Oligoribonucleotides; Oxidative Stress; Presenilin-1; Rats; Rats, Sprague-Dawley; Sirtuin 3

2018
Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson's disease.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Animals; Apomorphine; Biphenyl Compounds; Corpus Striatum; Disease Models, Animal; Lignans; Male; Mice; Microinjections; Motor Activity; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidopamine; Parkinson Disease, Secondary; Postural Balance; Substantia Nigra; Tyrosine 3-Monooxygenase

2018
Oral administration of honokiol attenuates airway inflammation in asthmatic mouse model.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:4

    Topics: Administration, Oral; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Lignans; Mice, Inbred BALB C; Respiratory System

2018
[Effects of honokiol on particulate matter 2.5-induced lung injury in asthmatic mice and its mechanisms].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Jul-28, Volume: 43, Issue:7

    Topics: Animals; Asthma; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Inflammation Mediators; Lignans; Lung; Lung Injury; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Particulate Matter; Random Allocation; Toll-Like Receptor 4

2018
Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway.
    Cellular & molecular biology letters, 2019, Volume: 24

    Topics: Acute Kidney Injury; Animals; Biphenyl Compounds; Disease Models, Animal; Heme Oxygenase-1; Kidney; Lignans; Male; Mice; MicroRNAs; Protective Agents; Sepsis; Signal Transduction

2019
Expression of vascular endothelial growth factor and glial fibrillary acidic protein in a rat model of traumatic brain injury treated with honokiol: a biochemical and immunohistochemical study.
    Folia morphologica, 2019, Volume: 78, Issue:4

    Topics: Animals; Biphenyl Compounds; Blood-Brain Barrier; Brain Injuries, Traumatic; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Immunohistochemistry; Lignans; Male; Malondialdehyde; Permeability; Peroxidase; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A

2019
Honokiol post-treatment ameliorates myocardial ischemia/reperfusion injury by enhancing autophagic flux and reducing intracellular ROS production.
    Chemico-biological interactions, 2019, Jul-01, Volume: 307

    Topics: Animals; Apoptosis; Autophagy; Biphenyl Compounds; Chloroquine; Disease Models, Animal; Lignans; Male; Mice; Mice, Inbred C57BL; Mitochondria; Myocardial Reperfusion Injury; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction

2019
Subinhibitory concentrations of Honokiol reduce α-Hemolysin (Hla) secretion by
    Emerging microbes & infections, 2019, Volume: 8, Issue:1

    Topics: A549 Cells; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Toxins; Biphenyl Compounds; Cell Survival; Disease Models, Animal; Hemolysin Proteins; Histocytochemistry; Humans; Inflammasomes; Lignans; Liver; Mice, Inbred C57BL; Molecular Docking Simulation; Protein Binding; Receptors, Cell Surface; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome

2019
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
    Molecules (Basel, Switzerland), 2019, May-28, Volume: 24, Issue:11

    Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Biphenyl Compounds; Brain; Calcium; Cytokines; Depression; Disease Models, Animal; Hindlimb Suspension; Immobilization; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Lignans; Lipopolysaccharides; Mice, Inbred ICR; NF-kappa B; RNA, Messenger; Swimming; Tryptophan

2019
Honokiol Attenuates the Memory Impairments, Oxidative Stress, Neuroinflammation, and GSK-3β Activation in Vascular Dementia Rats.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 71, Issue:1

    Topics: Animals; Biphenyl Compounds; Brain; Dementia, Vascular; Disease Models, Animal; Enzyme Activation; Glycogen Synthase Kinase 3 beta; Inflammation; Lignans; Maze Learning; Memory Disorders; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2019
Effects of honokiol on sepsis-induced acute kidney injury in an experimental model of sepsis in rats.
    Inflammation, 2014, Volume: 37, Issue:4

    Topics: Acute Kidney Injury; Animals; Antioxidants; Biphenyl Compounds; Cytokines; Disease Models, Animal; Inflammation; Kidney; Lignans; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis; Signal Transduction

2014
w007B protects brain against ischemia-reperfusion injury in rats through inhibiting inflammation, apoptosis and autophagy.
    Brain research, 2014, Apr-16, Volume: 1558

    Topics: Animals; Apoptosis; Autophagy; Biphenyl Compounds; Body Weight; Cerebrovascular Circulation; Disease Models, Animal; Female; Inflammation; Lignans; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sex Factors; Time Factors

2014
Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition.
    Neuropharmacology, 2014, Volume: 86

    Topics: Administration, Intravenous; Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Cell Cycle; Cell Survival; Cerebral Cortex; Cognition; Disease Models, Animal; Hippocampus; Lignans; Male; Motor Activity; Neurons; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Recovery of Function

2014
Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cell Line; Diet, High-Fat; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Fatty Liver; Hepatocytes; Humans; Lignans; Lipogenesis; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Signal Transduction; Sterol Regulatory Element Binding Protein 1

2015
Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice.
    European journal of pharmacology, 2014, Dec-05, Volume: 744

    Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Glutathione; Hippocampus; Inflammation; Interleukin-1beta; Interleukin-6; Lignans; Lipid Peroxidation; Lipopolysaccharides; Mice; Nitrites; Oxidative Stress; Prefrontal Cortex; Tumor Necrosis Factor-alpha

2014
Honokiol decreases intra-abdominal adhesion formation in a rat model.
    Gynecologic and obstetric investigation, 2015, Volume: 79, Issue:3

    Topics: Animals; Antioxidants; Biphenyl Compounds; Disease Models, Animal; Female; Lignans; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Uterus

2015
Anti-psoriatic effects of Honokiol through the inhibition of NF-κB and VEGFR-2 in animal model of K14-VEGF transgenic mouse.
    Journal of pharmacological sciences, 2015, Volume: 128, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; CD4-Positive T-Lymphocytes; Cells, Cultured; Disease Models, Animal; Down-Regulation; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Magnolia; Mice, Transgenic; Molecular Targeted Therapy; NF-kappa B; Phosphorylation; Phytotherapy; Psoriasis; Th1-Th2 Balance; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2015
Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Administration, Oral; Animals; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypoglycemic Agents; Injections, Intraperitoneal; Lignans; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Streptozocin; Structure-Activity Relationship

2015
Enhancing the anti-glioma therapy of doxorubicin by honokiol with biodegradable self-assembling micelles through multiple evaluations.
    Scientific reports, 2017, 02-27, Volume: 7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Doxorubicin; Drug Carriers; Drug Liberation; Drug Synergism; Humans; Lignans; Micelles; Nanoparticles; Neovascularization, Pathologic; Polyesters; Polyethylene Glycols; X-Ray Diffraction; Xenograft Model Antitumor Assays; Zebrafish

2017
Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Biphenyl Compounds; Cell Line, Tumor; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; fas Receptor; Fatty Acids; Fatty Liver, Alcoholic; Genes, Reporter; Glutathione; Lignans; Lipogenesis; Liver; Male; Promoter Regions, Genetic; Protective Agents; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transfection; Triglycerides; Tumor Necrosis Factor-alpha

2009
Chemopreventive effects of honokiol on UVB-induced skin cancer development.
    Anticancer research, 2010, Volume: 30, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Caspases; Disease Models, Animal; Female; Lignans; Mice; Neoplasms, Radiation-Induced; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2010
Characterization of neurotoxic effects of NMDA and the novel neuroprotection by phytopolyphenols in mice.
    Behavioral neuroscience, 2010, Volume: 124, Issue:4

    Topics: Analysis of Variance; Animals; Biphenyl Compounds; Ca(2+) Mg(2+)-ATPase; Calcium; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Flavonoids; Lignans; Linear Models; Male; Membrane Potential, Mitochondrial; Mice; Motor Activity; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenols; Phytotherapy; Polyphenols; Psychomotor Performance; Reactive Oxygen Species; Rotarod Performance Test; Silver Staining; Sodium-Potassium-Exchanging ATPase; Synaptosomes

2010
Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Nov-01, Volume: 185, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Biphenyl Compounds; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eosinophilia; Female; Fluorescent Antibody Technique; Hypersensitivity; Lignans; Lung; Mice; Mice, Inbred C57BL; Th2 Cells

2010
Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:5

    Topics: Acinar Cells; Acute Disease; Acute Lung Injury; Amylases; Animals; Apoptosis; Biphenyl Compounds; Caspase 3; Disease Models, Animal; Endoplasmic Reticulum; Enzyme Inhibitors; HMGB1 Protein; Interleukin-1beta; Lignans; Lipase; Lung; Male; Mice; Mice, Inbred BALB C; Pancreas; Pancreatitis; Time Factors; Transcription Factor CHOP; Tumor Necrosis Factor-alpha

2012
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.
    Neuropharmacology, 2005, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Lignans; Mice; N-Methylaspartate; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Sodium

2005
Honokiol, a small molecular weight natural product, alleviates experimental mesangial proliferative glomerulonephritis.
    Kidney international, 2006, Volume: 70, Issue:4

    Topics: Animals; Apoptosis; Biphenyl Compounds; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Extracellular Matrix Proteins; Gastrointestinal Agents; Glomerulonephritis, Membranoproliferative; Intercellular Adhesion Molecule-1; Lignans; Male; Proliferating Cell Nuclear Antigen; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thy-1 Antigens

2006
Effects of honokiol and magnolol on acute and inflammatory pain models in mice.
    Life sciences, 2007, Sep-08, Volume: 81, Issue:13

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Central Nervous System Depressants; Disease Models, Animal; Drug Evaluation, Preclinical; Fixatives; Formaldehyde; Inflammation; Lignans; Lumbosacral Region; Magnolia; Memory; Mice; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos

2007
Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Apr-01, Volume: 32, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exploratory Behavior; Hindlimb Suspension; Hydroxyindoleacetic Acid; Lignans; Magnolia; Male; Mice; Mice, Inbred ICR; Phytotherapy; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Swimming

2008
Honokiol, a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells.
    European journal of obstetrics, gynecology, and reproductive biology, 2008, Volume: 140, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Lignans; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms

2008